Electrochemical synthesis of cyclic biaryl λ³-bromanes from 2,2’-dibromobiphenyls

• Andrejs Savkins and
• Igors Sokolovs

Beilstein J. Org. Chem. 2025, 21, 451–457, doi:10.3762/bjoc.21.32

• ; electrochemistry; hypervalent bromine; Introduction Chemistry of hypervalent bromine(III) species has experienced rapid advancements during the recent years [1][2]. The remarkable nucleofugality of aryl bromides in hypervalent bromine(III) compounds has been exploited in the generation of arynes from cyclic

Predicting bond dissociation energies of cyclic hypervalent halogen reagents using DFT calculations and graph attention network model

• Yingbo Shao,
• Zhiyuan Ren,
• Zhihui Han,
• Li Chen,
• Yao Li and
• Xiao-Song Xue

Beilstein J. Org. Chem. 2024, 20, 1444–1452, doi:10.3762/bjoc.20.127

• become staples in organic chemistry, the exploration of their isoelectronic counterparts, namely hypervalent bromine(III) and chlorine(III) reagents, has been relatively limited, partly due to challenges in synthesizing and stabilizing these compounds. In this study, we conduct a thorough examination of

• results of this study could aid in estimating the chemical stability and functional group transfer capabilities of hypervalent bromine(III) and chlorine(III) reagents, thereby facilitating their development. Keywords: BDE; cyclic hypervalent halogen reagents; DFT calculation; graph attention network

• ][22], unsaturated alkane addition [23][24], and cyclization [25][26]. Despite the rapid development of hypervalent iodine(III) reagents, the exploration of isoelectronic hypervalent bromine(III) and chlorine(III) reagents has been comparatively limited despite their demonstrated potential for unique

Substitution of fluorine in M[C₆F₅BF₃] with organolithium compounds: distinctions between O- and N-nucleophiles

• Anton Yu. Shabalin,
• Nicolay Yu. Adonin and
• Vadim V. Bardin

Beilstein J. Org. Chem. 2017, 13, 703–713, doi:10.3762/bjoc.13.69

• Organoborates M[RBX3] (X = OAlk, F) are widely used in various fields of chemistry [1][2][3][4][5][6][7][8][9][10][11][12]. Their polyfluorinated analogues M[RFBX3] have been used as starting reagents in the synthesis of compounds of hypervalent bromine [13], iodine [14][15][16] and xenon [17][18][19][20][21