Five decades after the groundbreaking discovery of crown ethers, macrocyclic hosts remain vital to the field of supramolecular chemistry. The intrinsic cavity within these molecules renders them exceptional candidates for a wide array of supramolecular applications. These include catalysis, molecular and biomolecular recognition, chiral sensing, self-assembly, and the creation of complex interpenetrated architectures. Furthermore, their synthetic versatility positions macrocycles as invaluable building blocks in the self-assembly of supramolecular materials, which have demonstrated significant applications in environmental chemistry, catalysis, and sensing technologies.
This ongoing evolution in macrocycle chemistry is a testament to the ingenuity of scientists, who are constantly crafting innovative macrocyclic structures to enable increasingly sophisticated supramolecular functions and properties. There has been a surge in the discovery of new macrocycle classes, each finding diverse applications within the realm of supramolecular chemistry.
The aim of this Thematic Issue is to spotlight the most groundbreaking research on macrocyclic molecules and their supramolecular capabilities. Emphasis will be placed on the synthetic methodologies used to develop new hosts, alongside exploring the supramolecular properties and functions they support, such as catalysis, chiral sensing, the synthesis of mechanomolecules, and molecular and biomolecular recognition.
Submission deadline: March 31, 2025