The systemic effect of PEG-nGO-induced oxidative stress in vivo in a rodent model

• Qura Tul Ain,
• Samina Hyder Haq,
• Abeer Alshammari,
• Moudhi Abdullah Al-Mutlaq and
• Muhammad Naeem Anjum

Beilstein J. Nanotechnol. 2019, 10, 901–911, doi:10.3762/bjnano.10.91

• activity of GO [17]. Moreover, GO-based sensors have been used for the detection of neonicotinoids [18], tyrosine [19], ascorbic acid, dopamine, uric acid [20], 4-nitrophenol [21], and glucose [22]. Among all biocompatible polymers, PEG has been extensively used as a GO cover. Feng et al. used PEG and PEI

Polydopamine-coated Au nanorods for targeted fluorescent cell imaging and photothermal therapy

• Boris N. Khlebtsov,
• Andrey M. Burov,
• Timofey E. Pylaev and
• Nikolai G. Khlebtsov

Beilstein J. Nanotechnol. 2019, 10, 794–803, doi:10.3762/bjnano.10.79

• , 25% water solution), L-ascorbic acid (AA, >99.9%), hydrochloric acid (HCl, 37 wt % in water), folic acid (99.9%), thiolated polyethylene glycol (mPEG-SH, 99%), rhodamine 123 (BioReagent, for fluorescence, ≥85%) and sodium borohydride (NaBH4, 99%) were purchased from Sigma-Aldrich. Hydrogen

Self-assembly and wetting properties of gold nanorod–CTAB molecules on HOPG

• Imtiaz Ahmad,
• Floor Derkink,
• Tim Boulogne,
• Pantelis Bampoulis,
• Harold J. W. Zandvliet,
• Hidayat Ullah Khan,
• Rahim Jan and
• E. Stefan Kooij

Beilstein J. Nanotechnol. 2019, 10, 696–705, doi:10.3762/bjnano.10.69

• conceptual framework used in this work are similar to our work presented elsewhere [9][51]. Materials Hydrogen tetrachloroaurate (HAuCl4·3H2O, 99.999%, Aldrich), silver nitrate (AgNO3, 99%, Acros), ascorbic acid (AA, 99%, Merck), cetyltrimethylammonium bromide (CTAB, Aldrich, 98%), sodium borohydrate (NaBH4

Outstanding chain-extension effect and high UV resistance of polybutylene succinate containing amino-acid-modified layered double hydroxides

• Adam A. Marek,
• Vincent Verney,
• Christine Taviot-Gueho,
• Grazia Totaro,
• Laura Sisti,
• Annamaria Celli and
• Fabrice Leroux

Beilstein J. Nanotechnol. 2019, 10, 684–695, doi:10.3762/bjnano.10.68

• PBS nanocomposites. Nano-hybrid fillers (based on Mg2Al or Zn2Al LDH cations and with different anions from carboxylic and dicarboxylic acids, ascorbic acid and amino acids) were incorporated to PBS polymer by both methods: in situ polymerization and melt extrusion. Depending on the type of organic

Surface plasmon resonance enhancement of photoluminescence intensity and bioimaging application of gold nanorod@CdSe/ZnS quantum dots

• Siyi Hu,
• Yu Ren,
• Yue Wang,
• Jinhua Li,
• Junle Qu,
• Liwei Liu,
• Hanbin Ma and
• Yuguo Tang

Beilstein J. Nanotechnol. 2019, 10, 22–31, doi:10.3762/bjnano.10.3

• and biophotonics applications. Experimental Materials and instrumentation Hexadecyltrimethylammonium bromide (CTAB, >98.0%), L-ascorbic acid (BioUltra, ≥99.5%), silver nitrate (AgNO3, >99%), gold(III) chloride trihydrate (HAuCl4·3H2O, 99%), 3-mercaptopropionic acid (MPA, ≥99%), N-ethyl-N'-(3

• solution was prepared by mixing 800 μL of 25 mM HAuCl4 and 20 mL of HPLC water. Following this, 400 μL of 4.0 mM AgNO3 solution was added to the HAuCl4 solution, and then 20 mL of 0.2 M CTAB and 800 μL of 0.08 M ascorbic acid were added. This solution was kept in a water bath at 37 °C, and the solution

Fabrication of photothermally active poly(vinyl alcohol) films with gold nanostars for antibacterial applications

• Mykola Borzenkov,
• Maria Moros,
• Claudia Tortiglione,
• Serena Bertoldi,
• Nicola Contessi,
• Silvia Faré,
• Angelo Taglietti,
• Agnese D’Agostino,
• Piersandro Pallavicini,
• Maddalena Collini and
• Giuseppe Chirico

Beilstein J. Nanotechnol. 2018, 9, 2040–2048, doi:10.3762/bjnano.9.193

• ) were commercially available from Fluka. Poly(ethylene glycol) thiols ( = 5000 g/mol; SH-PEG5000–OCH3 and SH-PEG5000–COOH), polyethylene glycol tert-octylphenyl ether (Triton X-100), chloroauric acid, ascorbic acid, silver nitrate, and sodium borohydride were purchased from Sigma-Aldrich and used as

• order to 5 mL of an aqueous solution of Triton X-100 (0.2 M). Then, a 140–400 µL of an aqueous solution of ascorbic acid (0.0788 M) were added. The solution, after gentle mixing, became colorless. Soon after, 12 µL of the seed solution were added. The samples were allowed to equilibrate for 1 h at room

Facile phase transfer of gold nanorods and nanospheres stabilized with block copolymers

• Yaroslav I. Derikov,
• Georgiy A. Shandryuk,
• Raisa V. Talroze,
• Alexander A. Ezhov and
• Yaroslav V. Kudryavtsev

Beilstein J. Nanotechnol. 2018, 9, 616–627, doi:10.3762/bjnano.9.58

• solutions were mixed with 14.4 mL of a 0.2 М CTAB solution, followed by adding 0.15 mL of a 0.08 М ascorbic acid solution, with thorough stirring until the medium turned colorless. At this point, 78 μL of the seed solution was introduced and, upon short-term mixing, the growth solution was left for 3 h at

Sugarcane juice derived carbon dot–graphitic carbon nitride composites for bisphenol A degradation under sunlight irradiation

• Lan Ching Sim,
• Jing Lin Wong,
• Chen Hong Hak,
• Jun Yan Tai,
• Kah Hon Leong and
• Pichiah Saravanan

Beilstein J. Nanotechnol. 2018, 9, 353–363, doi:10.3762/bjnano.9.35

• recombination of electron–hole pairs [35]. A facile hydrothermal approach was adopted to synthesize CD/g-C3N4 using ascorbic acid as precursor to prepare CDs, showing higher hydrogen (H2) production than pure g-C3N4 under UV light irradiation [36]. A similar composite was also reported using 6-aminohexanoic

The role of ligands in coinage-metal nanoparticles for electronics

• Ioannis Kanelidis and
• Tobias Kraus

Beilstein J. Nanotechnol. 2017, 8, 2625–2639, doi:10.3762/bjnano.8.263

• combination with ascorbic acid and spherical silver seeds yielded rod-like structures in water by reduction of AgNO3. Jana, Gearheart, and Murphy suggested that CTAB forms micellar templates for the anisotropic growth of nanostructures [65]. Recent studies modified this picture and indicated that CTAB

• irregular shapes (coin-like or rounded nanoplates) [71]. Wang et al. modified gold nanoparticle seeds (20 nm in diameter) with different bifunctional ligands and used them to initiate gold shell growth in a solution of HAuCl4, cetyltrimethylammonium chloride, and ascorbic acid. The morphologies of the

Synthesis of metal-fluoride nanoparticles supported on thermally reduced graphite oxide

• Alexa Schmitz,
• Kai Schütte,
• Vesko Ilievski,
• Juri Barthel,
• Laura Burk,
• Rolf Mülhaupt,
• Junpei Yue,
• Bernd Smarsly and
• Christoph Janiak

Beilstein J. Nanotechnol. 2017, 8, 2474–2483, doi:10.3762/bjnano.8.247

• [BMIm][FeCl4] as carbon and iron source [68]. CuCl nanoplatelets were obtained from mixtures of a Cu-containing ionic liquid crystal and 6-O-palmitoyl ascorbic acid [69]. Analysis of the MFx@TRGO nanocomposite materials by (high-resolution) transmission electron microscopy ((HR-)TEM) (Figure 1, Figures

Methionine-mediated synthesis of magnetic nanoparticles and functionalization with gold quantum dots for theranostic applications

• Arūnas Jagminas,
• Agnė Mikalauskaitė,
• Vitalijus Karabanovas and
• Jūrate Vaičiūnienė

Beilstein J. Nanotechnol. 2017, 8, 1734–1741, doi:10.3762/bjnano.8.174

• magnetization value of the magnetic core. To eliminate this drawback, several methods for the deposition of the gold directly onto the surface of magnetic NPs have been proposed that are based on the reduction of Au(III) species by the typical reducing agents such as borohydride, ascorbic acid and citric acid

Selective detection of Mg²⁺ ions via enhanced fluorescence emission using Au–DNA nanocomposites

• Tanushree Basu,
• Khyati Rana,
• Niranjan Das and
• Bonamali Pal

Beilstein J. Nanotechnol. 2017, 8, 762–771, doi:10.3762/bjnano.8.79

• bromide (CTAB) and DL-dithiothreitol solution (DTT) were purchased from Sigma Aldrich. Sodium borohydride (NaBH4) and silver nitrate (AgNO3) were purchased from Rankem and Fisher Scientific, respectively. Chloroauric acid (HAuCl4·H2O), ascorbic acid, mercaptopropionic acid (MPA) and magnesium acetate (Mg

• growth solution (Solution B) was prepared by mixing 40 mL (100 mM CTAB), 1.7 mL (10 mM HAuCl4·H2O), 250 μL of 10 mM AgNO3 and 270 μL (100 mM) ascorbic acid. 460 μL of Solution A was then added to Solution B to initiate the growth of nanospheres and left undisturbed for 1 h. These AuNSs served as a

• solution into the aqueous mixture (40 mL) containing CTAB (100 mM), HAuCl4·H2O (1.7 mL, 10 mM), AgNO3 (250 µL, 10 mM) and ascorbic acid (270 µL, 100 mM) and pH adjusted to 1–2 with 1 M HCl [36]. The synthesized AuNRs were washed three times with deionized water by centrifugation at 8500 rpm for 15 min each

Synthesis of graphene–transition metal oxide hybrid nanoparticles and their application in various fields

• Arpita Jana,
• Elke Scheer and
• Sebastian Polarz

Beilstein J. Nanotechnol. 2017, 8, 688–714, doi:10.3762/bjnano.8.74

• agent of GO. NaBH4 is more effective at reducing the C=O group, while it has moderate efficiency in the reduction of epoxide and carboxylic acid [55]. Other reductants used for the chemical transformation of GO to graphene are hydroquinone [56], gaseous H2 [57], alkaline solution [58][59], and ascorbic

• acid [60]. Despite the chemical reagent reduction, other reduction processes are used for the conversion of GO to graphene, e.g., microwave irradiation [61][62], electrochemical reduction [63][64], thermal annealing [46][65], photocatalytic reduction [66], solvothermal reduction [67][68], thermal

α-((4-Cyanobenzoyl)oxy)-ω-methyl poly(ethylene glycol): a new stabilizer for silver nanoparticles

• Jana Lutze,
• Miguel A. Bañares,
• Marcos Pita,
• Andrea Haase,
• Andreas Luch and
• Andreas Taubert

Beilstein J. Nanotechnol. 2017, 8, 627–635, doi:10.3762/bjnano.8.67

• -ascorbic acid (≥99%, Roth), N,N’-dicyclohexylcarbodiimide (99%, Aldrich), poly(ethylene glycol) methyl ether (Mn = 4830 g·mol−1, Aldrich), silver nitrate (≥99%, Sigma-Aldrich), sodium hydroxide (>99%, Roth), and trisodium citrate dihydrate (99.7%, Merck) were used as received. Water with a resistivity of

• . Silver nanoparticle synthesis Citrate-coated SNPs were synthesized according to a procedure of Qin et al. [46] 4 mL of a 1.2·10−3 M aqueous ascorbic acid solution (4.8 µmol) and 4 mL of a 6·10−3 M aqueous trisodium citrate dihydrate solution (24 µmol) were combined and the pH was adjusted to 10.5 with a

• microscopy (TEM). TEM images of citrate@SNP and CBAmPEG@SNP (Figure 2) show spherical to ellipsoidal particles with diameters in the range of 10 to 40 nm with a broad size distribution. Some samples (Figure 2B) show a fair amount of rod-like particles, typical of the synthesis using ascorbic acid. After

Comparison of four methods for the biofunctionalization of gold nanorods by the introduction of sulfhydryl groups to antibodies

• Xuefeng Wang,
• Zhong Mei,
• Yanyan Wang and
• Liang Tang

Beilstein J. Nanotechnol. 2017, 8, 372–380, doi:10.3762/bjnano.8.39

• trihydrate (HAuCl4·3H2O; 99%), cetyltrimethylammonium bromide (CTAB), sodium borohydride (NaBH4; 99%), silver nitrate (AgNO3; 99%), L-ascorbic acid (AA), 1-ethyl-3-(3-dimethylaminopropyl)carbodiimidehydrochloride (EDC), sodium oleate (NaOL; >97%), hydrochloric acid (HCl, 37%), (3-mercaptopropyl

Voltammetric determination of polyphenolic content in pomegranate juice using a poly(gallic acid)/multiwalled carbon nanotube modified electrode

• Refat Abdel-Hamid and
• Emad F. Newair

Beilstein J. Nanotechnol. 2016, 7, 1104–1112, doi:10.3762/bjnano.7.103

• pomegranate juice without interference of ascorbic acid, fructose, potassium nitrate and barbituric acid. The obtained data were compared with the standard Folin–Ciocalteu spectrophotometric results. Keywords: electrochemical sensor; gallic acid; multiwalled carbon nanotubes; pomegranate juice; total

• determination is always a consideration in electroanalytical techniques. Therefore, the response of the SWAdSV method for GA on PGA/MWCNT/GCE in 0.2 M H3PO4 with some possible interfering compounds was studied. It is known that ascorbic acid (AA) is one of the main components present in natural samples. A fixed

Direct formation of gold nanorods on surfaces using polymer-immobilised gold seeds

• Majid K. Abyaneh,
• Pietro Parisse and
• Loredana Casalis

Beilstein J. Nanotechnol. 2016, 7, 809–816, doi:10.3762/bjnano.7.72

• of 0.2 M cetyltrimethylammonium bromide (CTAB), 250 μL of 0.01 M AuCl4−, 50 μL of 0.1 M ascorbic acid and 20 μL of 0.1 M HNO3 and kept undisturbed overnight at room temperature (ca. 24 °C). This step leads to the growth of protruded gold seeds into GNRs via seed-mediated growth. Atomic force

Unraveling the neurotoxicity of titanium dioxide nanoparticles: focusing on molecular mechanisms

• Bin Song,
• Yanli Zhang,
• Jia Liu,
• Xiaoli Feng,
• Ting Zhou and
• Longquan Shao

Beilstein J. Nanotechnol. 2016, 7, 645–654, doi:10.3762/bjnano.7.57

• , as well as through reduced ratios of ascorbic acid (AsA) to oxidized AsA (DAsA) and glutathione (GSH) to oxidized glutathione (GSSG). These changes implied that OS, induced by TiO2 NPs, mainly contributed to neurotoxicity. In addition, maternal exposure to TiO2 NPs was also shown to affect the OS

Surface coating affects behavior of metallic nanoparticles in a biological environment

• Darija Domazet Jurašin,
• Marija Ćurlin,
• Ivona Capjak,
• Tea Crnković,
• Marija Lovrić,
• Michal Babič,
• Daniel Horák,
• Ivana Vinković Vrček and
• Srećko Gajović

Beilstein J. Nanotechnol. 2016, 7, 246–262, doi:10.3762/bjnano.7.23

• pale yellow. After 30 min, the colloid darkened to a deep-yellow color indicating the formation of AgNPs. CITAgNPs were synthesized via the following protocol: 200 μL of the aqueous solution of ascorbic acid (AsA) with a concentration of 0.1 mM was added into 190 mL of boiling water, followed by

Synthesis and applications of carbon nanomaterials for energy generation and storage

• Marco Notarianni,
• Jinzhang Liu,
• Kristy Vernon and
• Nunzio Motta

Beilstein J. Nanotechnol. 2016, 7, 149–196, doi:10.3762/bjnano.7.17

• to obtain a C/O ratio of 8.6 and a conductivity of about 16.6 S/cm. Unfortunately, these values are still low when compared to the rGO obtained from the hydrazine derivative compounds. Other reducing agents such as ascorbic acid (C6H8O6) and hydroiodic (HI) acid have been recently proposed because of

• their potential to obtain higher quality rGO as compared with the product obtained from hydrazine derivative compounds. Fernández-Merino et al. [128] were able to obtain rGO with a C/O ratio of 12.5 and a conductivity of 77 S/cm with ascorbic acid while Moon et al. [130] obtained rGO with a C/O ratio of

Green and energy-efficient methods for the production of metallic nanoparticles

• Mitra Naghdi,
• Mehrdad Taheran,
• Satinder K. Brar,
• M. Verma,
• R. Y. Surampalli and
• J. R. Valero

Beilstein J. Nanotechnol. 2015, 6, 2354–2376, doi:10.3762/bjnano.6.243

Optimized design of a nanostructured SPCE-based multipurpose biosensing platform formed by ferrocene-tethered electrochemically-deposited cauliflower-shaped gold nanoparticles

• Wicem Argoubi,
• Maroua Saadaoui,
• Sami Ben Aoun and
• Noureddine Raouafi

Beilstein J. Nanotechnol. 2015, 6, 1840–1852, doi:10.3762/bjnano.6.187

• peroxide at low working potentials comparatively to the direct reduction of H2O2 (ca. 1.50 V/SCE). Moreover, the biosensor selectivity was examined using up to the tenfold amount of ascorbic acid and dopamine as interfering agents. From Figure 6d, one can see that the presence of these redox compounds did

• , produced in goat), bovine serum albumin (98%), ascorbic acid, dopamine, H2O2, silica gel 60 mesh and F254 nm fluorescent silica-coated aluminum TLC plates were purchased from Sigma-Aldrich (Germany) and used as received without further purification. All solvents used were of analytical grade and were used

• the enzymatic response in a PBS solution at an applied potential of 290 mV upon successive addition of 10 µM of H2O2 with 100 µM of dopamine (DA) and ascorbic acid (AA). Faradaic amount of charge (Q) resulting from gold reduction, percent variation of the amount of charge, charge transfer resistance

Mechanical properties of MDCK II cells exposed to gold nanorods

• Anna Pietuch,
• Bastian Rouven Brückner,
• David Schneider,
• Marco Tarantola,
• Christina Rosman,
• Carsten Sönnichsen and
• Andreas Janshoff

Beilstein J. Nanotechnol. 2015, 6, 223–231, doi:10.3762/bjnano.6.21

• mL of 0.1 M CTAB, 7 μL of 0.04 M silver nitrate (AgNO3), and 105 μL of 0.08 M ascorbic acid. Nanoparticle size was controlled by transmission electron microscopy (TEM). We determined a length of 38 ± 6.5 nm and a width of 17 ± 3 nm for nanorod and a diameter of 43 nm for spheres [25]. Concentrations

The distribution and degradation of radiolabeled superparamagnetic iron oxide nanoparticles and quantum dots in mice

• Denise Bargheer,
• Artur Giemsa,
• Barbara Freund,
• Markus Heine,
• Christian Waurisch,
• Gordon M. Stachowski,
• Stephen G. Hickey,
• Alexander Eychmüller,
• Jörg Heeren and
• Peter Nielsen

Beilstein J. Nanotechnol. 2015, 6, 111–123, doi:10.3762/bjnano.6.11

• rate of 0.5 mL/min. Particle detection was achieved via UV absorption at 280 nm. For iron detection, 200 µL of each fraction was treated with 50 µL of 5 M hydrochloric acid at 70 °C for 30 min. Afterwards, 150 µL of a 2 M acetate buffer (pH 4.8) containing 10% ascorbic acid was added to 50 µL of each

The fate of a designed protein corona on nanoparticles in vitro and in vivo

• Denise Bargheer,
• Julius Nielsen,
• Gabriella Gébel,
• Markus Heine,
• Sunhild C. Salmen,
• Roland Stauber,
• Horst Weller,
• Joerg Heeren and
• Peter Nielsen

Beilstein J. Nanotechnol. 2015, 6, 36–46, doi:10.3762/bjnano.6.5

• 150 µL of a 2 M acetate buffer (pH 4.8) containing 10% ascorbic acid was added to 50 µL of each fraction, followed by 100 µL of a solution of 50 mg bathophenanthroline in 50 mL water. After 15 min, the absorption was measured at 540 nm. Radioactivity measurements 59Fe in organs or living mice was