Potential of a deep eutectic solvent in silver nanoparticle fabrication for antibiotic residue detection

• Le Hong Tho,
• Bui Xuan Khuyen,
• Ngoc Xuan Dat Mai and
• Nhu Hoa Thi Tran

Beilstein J. Nanotechnol. 2024, 15, 426–434, doi:10.3762/bjnano.15.38

• regarding the detection of NFT and SDZ, we demonstrate application aspects of our product, showing the great potential of DESs in sensing and biomedical applications. Results and Discussion Formation of Ag NPs-DES We have developed new and simple strategy to fabricate Ag NPs-DES in which ascorbic acid was

Vinorelbine-loaded multifunctional magnetic nanoparticles as anticancer drug delivery systems: synthesis, characterization, and in vitro release study

• Zeynep Özcan and
• Afife Binnaz Hazar Yoruç

Beilstein J. Nanotechnol. 2024, 15, 256–269, doi:10.3762/bjnano.15.24

• ’ magnetization cycle, as Bloch and Neel theorized [11][13]. Superparamagnetic iron oxide nanoparticles for drug delivery, diagnosis, and cancer therapy have gained wider acceptance in biomedical applications [14]. They have received notable attention in clinical applications such as early disease diagnosis (e.g

Berberine-loaded polylactic acid nanofiber scaffold as a drug delivery system: The relationship between chemical characteristics, drug-release behavior, and antibacterial efficiency

• Le Thi Le,
• Hue Thi Nguyen,
• Liem Thanh Nguyen,
• Huy Quang Tran and
• Thuy Thi Thu Nguyen

Beilstein J. Nanotechnol. 2024, 15, 71–82, doi:10.3762/bjnano.15.7

• cytotoxicity test revealed that the BBR NPs/PLA nanofiber scaffold did not induce any changes in morphology and proliferation of MA-104 cell monolayers. It suggests that the BBR/PLA and BBR NPs/PLA nanofiber scaffolds can be used in different biomedical applications, such as wound dressing, drug delivery

• cytotoxic activity against MA-104 cells. Therefore, it is proposed that the BBR NPs/PLA nanofiber scaffold can be a potential candidate for broad biomedical applications, such as wound dressing, drug delivery, and tissue engineering. Conclusion PLA nanofiber scaffolds loaded with BBR powder and BBR NPs were

Influence of conductive carbon and MnCo₂O₄ on morphological and electrical properties of hydrogels for electrochemical energy conversion

• Sylwia Pawłowska,
• Karolina Cysewska,
• Yasamin Ziai,
• Jakub Karczewski,
• Piotr Jasiński and
• Sebastian Molin

Beilstein J. Nanotechnol. 2024, 15, 57–70, doi:10.3762/bjnano.15.6

• were tested for biomedical applications. Nevertheless, they show that the impedance trend that we obtained is similar to that of other hydrogel materials presented in the literature. Additionally, experimental EIS data was modelled with simple electrical equivalent circuit (insert in Figure 4a), where

Fluorescent bioinspired albumin/polydopamine nanoparticles and their interactions with Escherichia coli cells

• Eloïse Equy,
• Jordana Hirtzel,
• Sophie Hellé,
• Béatrice Heurtault,
• Eric Mathieu,
• Morgane Rabineau,
• Vincent Ball and
• Lydie Ploux

Beilstein J. Nanotechnol. 2023, 14, 1208–1224, doi:10.3762/bjnano.14.100

• bacteria. Inspired by the eumelanin aggregates in human skin, polydopamine nanoaggregates (here referred to as nanoparticles, i.e., PDA NPs) have emerged as promising nanovectors for biomedical applications [11][12], especially because of their biocompatibility [13][14] and photothermic properties [15][16

• , France UMR 7199, CNRS/University of Strasbourg, 74 route du Rhin, 67401 Illkirch, France CNRS, 23 rue du Loess, 67200 Strasbourg, France 10.3762/bjnano.14.100 Abstract Inspired by the eumelanin aggregates in human skin, polydopamine nanoparticles (PDA NPs) are promising nanovectors for biomedical

• applications, especially because of their biocompatibility. We synthesized and characterized fluorescent PDA NPs of 10–25 nm diameter based on a protein containing a lysine–glutamate diad (bovine serum albumin, BSA) and determined whether they can penetrate and accumulate in bacterial cells to serve as a

Curcumin-loaded albumin submicron particles with potential as a cancer therapy: an in vitro study

• Nittiya Suwannasom,
• Netsai Sriaksorn,
• Chutamas Thepmalee,
• Krissana Khoothiam,
• Ausanai Prapan,
• Hans Bäumler and
• Chonthida Thephinlap

Beilstein J. Nanotechnol. 2023, 14, 1127–1140, doi:10.3762/bjnano.14.93

• addition, the removal of sericin, which requires a degumming process, is a prerequisite for using silk cocoons in biomedical applications to reduce the risk of an inflammatory response [18]. However, this degumming process can lead to damage to the silk structure, increase the polydispersity of the silk

Nanoarchitectonics of photothermal materials to enhance the sensitivity of lateral flow assays

• Elangovan Sarathkumar,
• Rajasekharan S. Anjana and
• Ramapurath S. Jayasree

Beilstein J. Nanotechnol. 2023, 14, 988–1003, doi:10.3762/bjnano.14.82

• to control the nanoscale architecture makes them a great choice for biomedical applications [49][50]. Gold nanostructures such as spheres, rods, stars, shells, and cages are often used as photothermal agents [51][52]. The surface plasmon resonance frequency of gold nanomaterials can be easily

Biomimetics on the micro- and nanoscale – The 25th anniversary of the lotus effect

• Matthias Mail,
• Kerstin Koch,
• Thomas Speck,
• William M. Megill and
• Stanislav N. Gorb

Beilstein J. Nanotechnol. 2023, 14, 850–856, doi:10.3762/bjnano.14.69

• paper “Bioselectivity of silk protein-based materials and their bio-inspired applications” the importance of tailoring bioselective, biologically active, and multifunctional materials for biomedical applications in biomaterial research. The review was focused on two major topics, the first one being

Carboxylic acids and light interact to affect nanoceria stability and dissolution in acidic aqueous environments

• Matthew L. Hancock,
• Eric A. Grulke and
• Robert A. Yokel

Beilstein J. Nanotechnol. 2023, 14, 762–780, doi:10.3762/bjnano.14.63

• ; environmentally mediated dissolution; nanoceria; Introduction Background Ceria nanomaterials have many applications, including acting as redox catalysts/metal supports [1], sunscreens [2], heat-resistant coatings [3], and much more [4]. Biomedical applications of ceria-based compounds as therapeutics have the

Metal-organic framework-based nanomaterials as opto-electrochemical sensors for the detection of antibiotics and hormones: A review

• Akeem Adeyemi Oladipo,
• Saba Derakhshan Oskouei and
• Mustafa Gazi

Beilstein J. Nanotechnol. 2023, 14, 631–673, doi:10.3762/bjnano.14.52

Microneedle patches – the future of drug delivery and vaccination?

• Zahra Faraji Rad,
• Philip D. Prewett and
• Graham J. Davies

Beilstein J. Nanotechnol. 2023, 14, 494–495, doi:10.3762/bjnano.14.40

• availability of regulatory-approved MN patches for a wide range of clinical and biomedical applications. We are grateful to the authors for their excellent contributions to this thematic issue; we are very aware of the demands on their time. We also thank the Beilstein-Institut editorial team for their highly

Plasmonic nanotechnology for photothermal applications – an evaluation

• A. R. Indhu,
• L. Keerthana and
• Gnanaprakash Dharmalingam

Beilstein J. Nanotechnol. 2023, 14, 380–419, doi:10.3762/bjnano.14.33

• tunability of optothermal properties and enhanced stability, these nanostructures show a wide range of applications in optical sensors, steam generation, water desalination, thermal energy storage, and biomedical applications such as photothermal (PT) therapy. The PT effect, that is, the conversion of

Polymer nanoparticles from low-energy nanoemulsions for biomedical applications

• Santiago Grijalvo and
• Carlos Rodriguez-Abreu

Beilstein J. Nanotechnol. 2023, 14, 339–350, doi:10.3762/bjnano.14.29

• , particularly by the phase inversion composition method, and the use of these nanoemulsions as templates for the preparation of polymer nanoparticles for biomedical applications are reviewed. The methods of preparation, nature of the components in the formulation, and their impact on the physicochemical

• research on the fabrication of polymer nanoparticles from low-energy nanoemulsions, focusing on phase inversion composition. We particularly emphasize their biomedical applications as drug carriers. 2 Nanoemulsions Nanoemulsions are constituted by nanoscale droplets (20–200 nm) dispersed in a continuous

• surfactant/water/oil systems through the use of phase diagrams is usually needed. For biomedical applications, this is further complicated by the fact that the list of available components is restricted by regulations. The most straightforward strategy to obtain polymer nanoparticles from nanoemulsions is to

Overview of mechanism and consequences of endothelial leakiness caused by metal and polymeric nanoparticles

• Magdalena Lasak and
• Karol Ciepluch

Beilstein J. Nanotechnol. 2023, 14, 329–338, doi:10.3762/bjnano.14.28

• form one of the most selective permeability barriers [33] (Figure 4). Studies on NanoEL are a valuable source of information with respect to the potential future of biomedical applications. Designing NPs with optimal physicochemical properties could enable predicted and controlled leakiness, thus

• therapeutic effectiveness, regulated pharmacokinetics, known biodistribution, and minimal side effects are being sought. The mechanism of NanoEL shows great potential for future biomedical applications, but a more thorough investigation is still required [5]. Conclusion Effective transport of NPs to the

Recent progress in cancer cell membrane-based nanoparticles for biomedical applications

• Qixiong Lin,
• Yueyou Peng,
• Yanyan Wen,
• Xiaoqiong Li,
• Donglian Du,
• Weibin Dai,
• Wei Tian and
• Yanfeng Meng

Beilstein J. Nanotechnol. 2023, 14, 262–279, doi:10.3762/bjnano.14.24

Concentration-dependent photothermal conversion efficiency of gold nanoparticles under near-infrared laser and broadband irradiation

• Vikas,
• Raj Kumar and
• Sanjeev Soni

Beilstein J. Nanotechnol. 2023, 14, 205–217, doi:10.3762/bjnano.14.20

• Vikas Raj Kumar Sanjeev Soni Academy of Scientific and Innovative Research (AcSIR), Ghaziabad-201002, India Biomedical Applications Group, CSIR ­ Central Scientific Instruments Organisation, Sector-30C, Chandigarh-160030, India Micro and Nano Optics Centre, CSIR ­ Central Scientific Instruments

• , and the characteristics of irradiation source [12][13][14][15][16][17]. For biomedical applications, to achieve maximum light penetration, a light source of spectral output within 700–900 nm (NIR-I range, termed therapeutic window) is required [18][19][20]. Here, the photothermal conversion efficiency

Structural, optical, and bioimaging characterization of carbon quantum dots solvothermally synthesized from o-phenylenediamine

• Zoran M. Marković,
• Milica D. Budimir,
• Martin Danko,
• Dušan D. Milivojević,
• Pavel Kubat,
• Danica Z. Zmejkoski,
• Vladimir B. Pavlović,
• Marija M. Mojsin,
• Milena J. Stevanović and
• Biljana M. Todorović Marković

Beilstein J. Nanotechnol. 2023, 14, 165–174, doi:10.3762/bjnano.14.17

• o-phenylenediamine did not disrupt the cytoplasmic membrane. Cytotoxicity testing Low cytotoxicity is one of the mandatory requirements for biomedical applications. In this paper, we performed cell viability tests by applying the MTT assay toward MRC5 human lung fibroblast cells. Lung fibroblasts

Two-step single-reactor synthesis of oleic acid- or undecylenic acid-stabilized magnetic nanoparticles by thermal decomposition

• Mykhailo Nahorniak,
• Pamela Pasetto,
• Jean-Marc Greneche,
• Volodymyr Samaryk,
• Sandy Auguste,
• Anthony Rousseau,
• Nataliya Nosova and
• Serhii Varvarenko

Beilstein J. Nanotechnol. 2023, 14, 11–22, doi:10.3762/bjnano.14.2

• , wüstite), particularly nanosized particles, show distinct effects on living organisms. Thus, it is of primary importance for their biomedical applications that the morphology and phase-structural state of these materials are investigated. The aim of this work was to obtain magnetic nanoparticles in a

• chemical and physical properties. One such area is biomedicine [1]. Especially iron oxide-based nanoparticles, due to their biodegradation, low toxicity, and enhanced oxidative resistance compared to metallic nanoparticles, show high potential in biomedical applications [2][3][4]. Up to now, iron oxide

• , studying the morphology and phase composition of iron-oxide-based nanoparticles is a critical issue. Nevertheless, magnetite and maghemite particles remain the most commonly used nanoparticles in biomedical applications. However, it must be noted that magnetite nanoparticles undergo rapid oxidation in air

Single-step extraction of small-diameter single-walled carbon nanotubes in the presence of riboflavin

• Polina M. Kalachikova,
• Anastasia E. Goldt,
• Eldar M. Khabushev,
• Timofei V. Eremin,
• Timofei S. Zatsepin,
• Elena D. Obraztsova,
• Konstantin V. Larionov,
• Liubov Yu. Antipina,
• Pavel B. Sorokin and
• Albert G. Nasibulin

Beilstein J. Nanotechnol. 2022, 13, 1564–1571, doi:10.3762/bjnano.13.130

• . Biomedical applications apply an additional constraint on the diameter of nanotubes. Small-diameter SWCNTs display intrinsic photoluminescence in the spectral range of 900–1100 nm within the biological transparency window, making them ideal candidates for single-molecule biosensors or biomedical imaging

• biocompatibility of nucleic acids can support biomedical applications of such dispersions. Unfortunately, an extensive ultrasonic treatment required to obtain a dispersion of individual nanotubes might destroy fragile nucleic acid molecules so that their applications are somewhat inhibited. Flavin compounds are

• . Such optimization of the extraction procedure promotes biomedical applications of (6,5)-SWCNTs since final dispersions do not contain surfactants or organic solvents incompatible with living systems. Experimental Materials CoMoCat (SG65i, ≥95% semiconducting SWCNTs) and Tuball (≥80% SWCNTs) SWCNTs were

Facile preparation of Au- and BODIPY-grafted lipid nanoparticles for synergized photothermal therapy

• Yuran Wang,
• Xudong Li,
• Haijun Chen and
• Yu Gao

Beilstein J. Nanotechnol. 2022, 13, 1432–1444, doi:10.3762/bjnano.13.118

• development of Au- and BODIPY-grafted LNPs using a very simple and convenient method. PTT-induced direct anti-tumor effects through photothermal ablation or hyperthermia have been widely studied [28]. AuNPs are one of the most attractive PTAs for biomedical applications because of their biocompatibility and

Role of titanium and organic precursors in molecular layer deposition of “titanicone” hybrid materials

• Arbresha Muriqi and
• Michael Nolan

Beilstein J. Nanotechnol. 2022, 13, 1240–1255, doi:10.3762/bjnano.13.103

• organic–inorganic hybrid films for applications in several technological application areas, including packaging/encapsulation, electronics, batteries and biomedical applications [1][2][3][4]. MLD is very similar to the widely used atomic layer deposition (ALD) technique, which involves the fabrication of

Recent advances in green carbon dots (2015–2022): synthesis, metal ion sensing, and biological applications

• Aisha Kanwal,
• Naheed Bibi,
• Sajjad Hyder,
• Arif Muhammad,
• Hao Ren,
• Jiangtao Liu and
• Zhongli Lei

Beilstein J. Nanotechnol. 2022, 13, 1068–1107, doi:10.3762/bjnano.13.93

• properties of CDs. By introducing electrons into CDs and altering the internal electronic states, nitrogen atoms significantly enhance the fluorescence characteristics of these molecules. The N-CDs produced perform exceptionally well in biomedical applications, including bioimaging and biosensing. A huge

Biomimetic chitosan with biocomposite nanomaterials for bone tissue repair and regeneration

• Se-Kwon Kim,
• Sesha Subramanian Murugan,
• Pandurang Appana Dalavi,
• Sebanti Gupta,
• Sukumaran Anil,
• Gi Hun Seong and
• Jayachandran Venkatesan

Beilstein J. Nanotechnol. 2022, 13, 1051–1067, doi:10.3762/bjnano.13.92

• demonstrated the best biocompatible behaviour which is suitable for bone tissue engineering applications [80]. Chitosan–graphene oxide nanocomposites Graphene oxide is gaining much attention in biomedical applications including drug delivery, tissue engineering, and bioimaging applications due to its large

• , graphene oxide, and biosilica nanocomposites has bioconductive and osteoinductive behaviour with suitable mechanical strength. The chitosan–graphene oxide composite is gaining much attention in biomedical applications including drug delivery, tissue engineering, and bioimaging, due to its large surface

Bioselectivity of silk protein-based materials and their bio-inspired applications

• Hendrik Bargel,
• Vanessa T. Trossmann,
• Christoph Sommer and
• Thomas Scheibel

Beilstein J. Nanotechnol. 2022, 13, 902–921, doi:10.3762/bjnano.13.81

• tissue formation. Conversely, the adhesion and presence of microbes interferes with important multicellular processes of tissue development. Therefore, tailoring bioselective, biologically active, and multifunctional materials for biomedical applications is a modern focus of biomaterial research

• , slow biodegradation, low immunogenicity, and non-toxicity, making them ideally suited for tissue engineering and biomedical applications. Furthermore, recombinant production technologies allow for application-specific modification to develop adjustable, bioactive materials. The present review focusses

• while simultaneously preventing microbial infestation and biofouling would exhibit a best-of-both-worlds approach for a number of biomedical applications. For instance, it has been shown that the surface modification of glass substrates with the cell-binding motif RGD of fibronectin and collagen

Recent advances in nanoarchitectures of monocrystalline coordination polymers through confined assembly

• Lingling Xia,
• Qinyue Wang and
• Ming Hu

Beilstein J. Nanotechnol. 2022, 13, 763–777, doi:10.3762/bjnano.13.67

• discuss the properties of the coordination polymer single crystals as well as their performance in energy, environmental, and biomedical applications. Keywords: applications; assembly; coordination polymer; metal-organic frameworks; nanoarchitectonics; Introduction Coordination polymers are hybrid

• +molecules’@crystal, and micro–meso–macroporous crystals. The physiochemical properties of the nanoarchitectures were changed significantly compared with pure coordination polymers, making the coordination polymer suitable for applications such as batteries, sensors, biomedical applications. When the