New trends in nanobiotechnology

• Pau-Loke Show,
• Kit Wayne Chew,
• Wee-Jun Ong,
• Sunita Varjani and
• Joon Ching Juan

Beilstein J. Nanotechnol. 2023, 14, 377–379, doi:10.3762/bjnano.14.32

• works on self-assembly have shown low synthesis cost, ease of modelling, and good biocompatibility of the generated biomolecules. The review discusses the introduction and case studies of different types of self-assembly, applying examples on the application of the method. Finally, the review summarizes

Biocatalytic synthesis and ordered self-assembly of silica nanoparticles via a silica-binding peptide

• Mustafa Gungormus

Beilstein J. Nanotechnol. 2023, 14, 280–290, doi:10.3762/bjnano.14.25

• methods for manufacturing ordered structures of nanoparticles is an ongoing challenge. Ordered structures of SiO2 nanoparticles have gained increased attention due to the great potential they offer in filtering, separation, drug delivery, optics, electronics, and catalysis. Biomolecules, such as peptides

• monodisperse nanoparticles and to modify the surface properties to fully exploit the advantages offered by self-assembly. Biomolecules, such as peptides and proteins, have been demonstrated to be useful in the synthesis and self-assembly of inorganic nanostructures [15][16]. Herein, we have investigated the

Antimicrobial and mechanical properties of functionalized textile by nanoarchitectured photoinduced Ag@polymer coating

• Jessica Plé,
• Marine Dabert,
• Helene Lecoq,
• Sophie Hellé,
• Lydie Ploux and
• Lavinia Balan

Beilstein J. Nanotechnol. 2023, 14, 95–109, doi:10.3762/bjnano.14.11

• , the same medium was chosen for both bacteria and fungus. M63G medium has been preferred since it does not reduce silver antimicrobial activity contrary to media containing components such as Cl− or other biomolecules, which interact with ionic silver [20]. In addition, it provides nutrient conditions

Combining physical vapor deposition structuration with dealloying for the creation of a highly efficient SERS platform

• Adrien Chauvin,
• Walter Puglisi,
• Damien Thiry,
• Cristina Satriano,
• Rony Snyders and
• Carla Bittencourt

Beilstein J. Nanotechnol. 2023, 14, 83–94, doi:10.3762/bjnano.14.10

• straightforward synthesis together with the easy operability of this platform make it very promising for practical applications such as detection of low concentrations of pollutants or biomolecules. Experimental Synthesis of Ag–Al thin films The synthesis approach of Ag–Al thin films and the dealloying procedure

Single-step extraction of small-diameter single-walled carbon nanotubes in the presence of riboflavin

• Polina M. Kalachikova,
• Anastasia E. Goldt,
• Eldar M. Khabushev,
• Timofei V. Eremin,
• Timofei S. Zatsepin,
• Elena D. Obraztsova,
• Konstantin V. Larionov,
• Liubov Yu. Antipina,
• Pavel B. Sorokin and
• Albert G. Nasibulin

Beilstein J. Nanotechnol. 2022, 13, 1564–1571, doi:10.3762/bjnano.13.130

• another class of biomolecules that can be potentially utilized as a surfactant for dispersing SWCNTs. Having relatively low solubility in water, flavins are generally innocuous for living cells. Riboflavin (also known as vitamin B2) is a precursor of such coenzymes as flavin mononucleotide phosphate and

Rapid and sensitive detection of box turtles using an electrochemical DNA biosensor based on a gold/graphene nanocomposite

• Abu Hashem,
• M. A. Motalib Hossain,
• Ab Rahman Marlinda,
• Mohammad Al Mamun,
• Khanom Simarani and
• Mohd Rafie Johan

Beilstein J. Nanotechnol. 2022, 13, 1458–1472, doi:10.3762/bjnano.13.120

• surface-to-volume ratio [37][38][43][44][45][46]. Biomolecules such as DNA may readily modify AuNPs by adding thiol and amine groups via Au–S or Au–N links without losing their activity [38][47]. In electrocatalytic applications, the combination of carbon-based materials with metal nanoparticles has been

Design of surface nanostructures for chirality sensing based on quartz crystal microbalance

• Yinglin Ma,
• Xiangyun Xiao and
• Qingmin Ji

Beilstein J. Nanotechnol. 2022, 13, 1201–1219, doi:10.3762/bjnano.13.100

• layers, composed of biomolecules, polymers, supramolecular assemblies, and functional organic hybrids have been successfully constructed on the surface of QCM electrodes. According to frequency shifts of QCM upon adsorption, detection efficiencies of various selectors for chiral analytes could be

• evaluated. The recognition mechanisms may also be studied by combining QCM with other techniques. Sensing layers by chiral biomolecules As chiral recognitions are fundamental phenomena in biology, biomolecules of amino acids, proteins, and nucleic acids are ideal chiral selectors. They have been extensively

• affinity between proteins and chiral selectors. It was elucidated that stereoselective hydrophobic interactions are the major driving forces that govern protein adsorption on ʟ-Val-modified surfaces. Besides small biomolecules, biological macromolecules, such as proteins and enzymes, also show natural

Recent advances in green carbon dots (2015–2022): synthesis, metal ion sensing, and biological applications

• Aisha Kanwal,
• Naheed Bibi,
• Sajjad Hyder,
• Arif Muhammad,
• Hao Ren,
• Jiangtao Liu and
• Zhongli Lei

Beilstein J. Nanotechnol. 2022, 13, 1068–1107, doi:10.3762/bjnano.13.93

• manufacturing CDs from these plant components. Plant-based precursors that contain heteroatoms (nitrogen and sulfur) are preferred over carbon sources that demand supplementary heteroatoms for the synthesis of CDs [53]. Without surface-passivating agent: Plants are rich in biomolecules such as carbohydrates and

DNA aptamer selection and construction of an aptasensor based on graphene FETs for Zika virus NS1 protein detection

• Nathalie B. F. Almeida,
• Thiago A. S. L. Sousa,
• Viviane C. F. Santos,
• Camila M. S. Lacerda,
• Thais G. Silva,
• Rafaella F. Q. Grenfell,
• Flavio Plentz and
• Antero S. R. Andrade

Beilstein J. Nanotechnol. 2022, 13, 873–881, doi:10.3762/bjnano.13.78

• the human serum already contains a plethora of interfering biomolecules [25]. Figure S1b (Supporting Information File 1) exhibits a schematic illustration of the resulting ZIKV60-functionalized graphene devices and the experimental setup used in the electrical characterization for ZIKV NS1 protein

A nonenzymatic reduced graphene oxide-based nanosensor for parathion

• Sarani Sen,
• Anurag Roy,
• Ambarish Sanyal and
• Parukuttyamma Sujatha Devi

Beilstein J. Nanotechnol. 2022, 13, 730–744, doi:10.3762/bjnano.13.65

• after pesticide use. Due to its high nondegradability, pesticides can stay more often on the surface of fruits and vegetables; sometimes, it can also penetrate into the peel of vegetables and fruits [1]. Organophosphorus insecticides react with biomolecules either via deoxyribonucleic acid (DNA

• samples are i) the high cost of the enzyme, ii) low stability of biomolecules at room temperature, and iii) difficulties in using interference-free selective detection of a specific OP. However, nonenzymatic electrochemical nanosensors could easily be employed as rapid, cost-effective, easy-to-handle

Detection and imaging of Hg(II) in vivo using glutathione-functionalized gold nanoparticles

• Gufeng Li,
• Shaoqing Li,
• Rui Wang,
• Min Yang,
• Lizhu Zhang,
• Yanli Zhang,
• Wenrong Yang and
• Hongbin Wang

Beilstein J. Nanotechnol. 2022, 13, 549–559, doi:10.3762/bjnano.13.46

• (–NH2), and carboxyl (–COOH) groups [11][12][13][14]. The surface of GNPs can be easily modified with good stability. Thus, they can penetrate the cell membrane and selectively interact with target biomolecules in cells [15][16][17][18]. So far, a variety of functionalized GNPs, whose properties were

Impact of device design on the electronic and optoelectronic properties of integrated Ru-terpyridine complexes

• Max Mennicken,
• Sophia Katharina Peter,
• Corinna Kaulen,
• Ulrich Simon and
• Silvia Karthäuser

Beilstein J. Nanotechnol. 2022, 13, 219–229, doi:10.3762/bjnano.13.16

• growth, to include additional functionalities or to form bridges to biomolecules [4][5]. Common ligands, particularly suitable for the metallo-supramolecular wire growth and exhibiting high binding constants to a broad range of transition metal ions, are often based on 2,2′:6′,2″-terpyridine (TP) motives

Engineered titania nanomaterials in advanced clinical applications

• Padmavati Sahare,
• Paulina Govea Alvarez,
• Juan Manual Sanchez Yanez,
• Gabriel Luna-Bárcenas,
• Samik Chakraborty,
• Sujay Paul and
• Miriam Estevez

Beilstein J. Nanotechnol. 2022, 13, 201–218, doi:10.3762/bjnano.13.15

• excretion [33]. When a TiO2 nanomaterial circulates through the body, certain biomolecules (such as proteins, phospholipids, or DNA contained in biological fluids or present in living cells) get adsorbed onto the surface of it very quickly, which is termed as “protein corona (PC)” formation. This protein

Sputtering onto liquids: a critical review

• Anastasiya Sergievskaya,
• Adrien Chauvin and
• Stephanos Konstantinidis

Beilstein J. Nanotechnol. 2022, 13, 10–53, doi:10.3762/bjnano.13.2

• presence of undesired contaminants, such as fragments of biological materials, which require complicated, expensive, and time-consuming purification procedures. Bio-assisted methods can be divided into three categories according to the system used: (i) microorganisms, (ii) biomolecules, and (iii) plant

Alteration of nanomechanical properties of pancreatic cancer cells through anticancer drug treatment revealed by atomic force microscopy

• Xiaoteng Liang,
• Shuai Liu,
• Xiuchao Wang,
• Dan Xia and
• Qiang Li

Beilstein J. Nanotechnol. 2021, 12, 1372–1379, doi:10.3762/bjnano.12.101

• caused by the more complex distribution of biomolecules, such as proteins and sugars, existing on the normal cell membrane surface than that on the cancer cell surface [28][29][30]. The statistics of the Young's modulus values of the four kinds of cells are illustrated in Figure 4a. The Young’s modulus

Self-assembly of amino acids toward functional biomaterials

• Huan Ren,
• Lifang Wu,
• Lina Tan,
• Yanni Bao,
• Yuchen Ma,
• Yong Jin and
• Qianli Zou

Beilstein J. Nanotechnol. 2021, 12, 1140–1150, doi:10.3762/bjnano.12.85

• Huan Ren Lifang Wu Lina Tan Yanni Bao Yuchen Ma Yong Jin Qianli Zou School of Pharmacy, Anhui Medical University, Hefei 230032, China 10.3762/bjnano.12.85 Abstract Biomolecules, such as proteins and peptides, can be self-assembled. They are widely distributed, easy to obtain, and biocompatible

• -ordered structures from a complex mixture via noncovalent interactions, including van der Waals forces, electrostatic forces, hydrogen bonds, and stacking interactions [12][13]. Importantly, biomolecules, such as proteins, peptides, or biologically derived molecules, including de novo designed peptides or

• biomolecules, such as proteins, peptides, and DNA have received extensive attention in recent years [86]. Liu et al. [87] used electrostatic force to adsorb tetrakis(4-sulfonatophenyl)porphine (TPPS) molecules on the surface of 9-fluorenylmethoxycarbonyl-ʟ-lysine (Fmoc-ʟ-Lys) self-assembled nanofibers such

Use of nanosystems to improve the anticancer effects of curcumin

• Andrea M. Araya-Sibaja,
• Norma J. Salazar-López,
• Krissia Wilhelm Romero,
• José R. Vega-Baudrit,
• J. Abraham Domínguez-Avila,
• Carlos A. Velázquez Contreras,
• Ramón E. Robles-Zepeda,
• Mirtha Navarro-Hoyos and
• Gustavo A. González-Aguilar

Beilstein J. Nanotechnol. 2021, 12, 1047–1062, doi:10.3762/bjnano.12.78

• subcellular anticancer therapies which carry the drug and better focus it on the intended target. They are also able to contain molecules that respond to endogenous (tumor microenvironment, including redox potential, pH, enzymes, ions, or biomolecules) and/or exogenous stimuli (light, electromagnetic fields

Modification of a SERS-active Ag surface to promote adsorption of charged analytes: effect of Cu²⁺ ions

• Bahdan V. Ranishenka,
• Andrei Yu. Panarin,
• Irina A. Chelnokova,
• Sergei N. Terekhov,
• Peter Mojzes and
• Vadim V. Shmanai

Beilstein J. Nanotechnol. 2021, 12, 902–912, doi:10.3762/bjnano.12.67

• remaining polymer molecules are not able to generate a strong positive charge at the surface but they improve the adsorption of the analyte molecules due to hydrogen bonding and donor–acceptor and lipophilic interactions. SERS analysis of dye-labeled oligonucleotides Biomolecules such as nucleotides and

• nucleic acids are of great interest for practical SERS applications. Oligonucleotides are the most suitable biomolecules for electrostatic interaction studies because of their strong negative charge. Recently, we showed the crucial role of electrostatic interactions of oligonucleotides with NP surfaces

Comprehensive review on ultrasound-responsive theranostic nanomaterials: mechanisms, structures and medical applications

• Sepand Tehrani Fateh,
• Lida Moradi,
• Elmira Kohan,
• Michael R. Hamblin and
• Amin Shiralizadeh Dezfuli

Beilstein J. Nanotechnol. 2021, 12, 808–862, doi:10.3762/bjnano.12.64

Recent progress in magnetic applications for micro- and nanorobots

• Ke Xu,
• Shuang Xu and
• Fanan Wei

Beilstein J. Nanotechnol. 2021, 12, 744–755, doi:10.3762/bjnano.12.58

• in the fluid under the influence of the rotating magnetic field. Higher viscosity fluids made the helix-like shaped MNRs swim faster. In order to further promote the functionalization of biomolecules, a layer of titanium was deposited on the outside, which not only served as a protective layer, but

Fate and transformation of silver nanoparticles in different biological conditions

• Barbara Pem,
• Marija Ćurlin,
• Darija Domazet Jurašin,
• Valerije Vrček,
• Rinea Barbir,
• Vedran Micek,
• Raluca M. Fratila,
• Jesus M. de la Fuente and
• Ivana Vinković Vrček

Beilstein J. Nanotechnol. 2021, 12, 665–679, doi:10.3762/bjnano.12.53

• will not be retained in biological media [9][10][11][12][13][14]. In biological media, AgNPs may be transformed into different forms by aggregation, agglomeration, dissolution, interaction with biomolecules, or generation of reactive oxygen species (ROS) that may lead to the coexistence of

• association of Ag with sulphur and the formation of Ag2S granules from ion exchange or Ag–thiol complexes is known as sulphidation [28][29]. However, many other scenarios should be considered during an in vivo journey of AgNPs and Ag+ ions, especially their interactions with biomolecules, such as lipids

• and BP media. We tried to quantify the release of Ag+ from the surface of different AgNPs incubated in WB or tissue homogenates. However, all the attempts to extract free Ag+ ions from such media by ultracentrifuge filtration failed. Probably, free Ag+ ions were either bound to biomolecules or

A review of defect engineering, ion implantation, and nanofabrication using the helium ion microscope

• Frances I. Allen

Beilstein J. Nanotechnol. 2021, 12, 633–664, doi:10.3762/bjnano.12.52

• biomolecules by optical means, as opposed to having to rely on the conventional ionic current method. Nanopore fabrication using the HIM is discussed in more detail in Section 5. The HIM has also been used to tune the optical properties of quantum well structures [61]. In this work, epitaxially grown InGaAs

On the stability of microwave-fabricated SERS substrates – chemical and morphological considerations

• Limin Wang,
• Aisha Adebola Womiloju,
• Christiane Höppener,
• Ulrich S. Schubert and
• Stephanie Hoeppener

Beilstein J. Nanotechnol. 2021, 12, 541–551, doi:10.3762/bjnano.12.44

• choice of a suitable media is of utmost importance for many biological investigations as it can alter the structure of biomolecules (e.g., proteins) [33]. We tested five commonly used buffer systems which include phosphate-buffered saline (PBS), HEPES-buffered glucose solution (HBG), tris-borate-EDTA

Surface-enhanced Raman scattering of water in aqueous dispersions of silver nanoparticles

• Paulina Filipczak,
• Krzysztof Hałagan,
• Jacek Ulański and
• Marcin Kozanecki

Beilstein J. Nanotechnol. 2021, 12, 497–506, doi:10.3762/bjnano.12.40

• discovery of the SERS effect in 1974 [27], most of the research is focused on biomolecules and medical applications [28][29]. The SERS effect of water has been studied since 1980. There are reports on the SERS effect of water in aqueous solutions of electrolytes placed between metal electrodes (Ag, Au, Cu

A review on nanostructured silver as a basic ingredient in medicine: physicochemical parameters and characterization

• Gabriel M. Misirli,
• Kishore Sridharan and
• Shirley M. P. Abrantes

Beilstein J. Nanotechnol. 2021, 12, 440–461, doi:10.3762/bjnano.12.36

• effective in inhibiting SARS-CoV-2 by using AgNPs to coat facial masks [77][120]. These results are suggestive of the development of new measures in which AgNPs can be used to prevent SARS-CoV-2 infection. Biological interactions of AgNPs When in contact with human plasma, AgNPs adsorb biomolecules such as