Rapid synthesis of highly monodisperse AgSbS₂ nanocrystals: unveiling multifaceted activities in cancer therapy, antibacterial strategies, and antioxidant defense

• Funda Ulusu,
• Adem Sarilmaz,
• Yakup Ulusu,
• Faruk Ozel and
• Mahmut Kus

Beilstein J. Nanotechnol. 2025, 16, 2105–2115, doi:10.3762/bjnano.16.145

• . [26]. Bacterial suspensions (S. aureus, B. subtilis, and E. coli) were prepared in Mueller–Hinton broth (MHB; Merck, Germany) at a density equivalent to 0.5 McFarland and adjusted to 105–106 CFU/mL. Sample stock solutions (10 mg/mL in 1% DMSO) were serially diluted in 96-well plates to final

• ]. NCs were dissolved in DMSO (10 mg/mL) stock and the DMSO concentration in the cell culture medium was not more than 0.1%. Cells were seeded in 96-well plates at a density of 2 × 104 cells/well, and the plates were incubated in a humidified incubator (95% air and 5% CO2) at 37 °C for 24 h. Triplicate

Toward clinical translation of carbon nanomaterials in anticancer drug delivery: the need for standardisation

• Michał Bartkowski,
• Francesco Calzaferri and
• Silvia Giordani

Beilstein J. Nanotechnol. 2025, 16, 2092–2104, doi:10.3762/bjnano.16.144

• to maintain the desired therapeutic and safety profiles. Assessing this aspect includes quantifying the density and distribution of attached ligands or therapeutic agents. In addition to evaluating the NMs themselves, the manufacturing process must be carefully monitored. Reproducibility, scalability

• peroxidase, or UV-assisted photo-Fenton processes. Notably, oxidised CNOs degrade more readily than their pristine counterparts, due to their higher defect density and greater abundance of oxygen-containing functional groups [42]. These findings highlight that the biodegradability of CNMs strongly depends on

• requires systematic assessment, quantification, and reporting of CNM properties, including size, shape, stability, surface charge and functionalisation, as well as payload density and distribution. Once production and characterisation procedures are standardised, the preclinical evaluation of carbon-based

Multifrequency AFM integrating PeakForce tapping and higher eigenmodes for heterogeneous surface characterization

• Yanping Wei,
• Jiafeng Shen,
• Yirong Yao,
• Xuke Li,
• Ming Li and
• Peiling Ke

Beilstein J. Nanotechnol. 2025, 16, 2077–2085, doi:10.3762/bjnano.16.142

• record its thermal vibration power spectral density. A fit to the fundamental resonance peak, based on the equipartition theorem, yielded the spring constant. Characterization of higher eigenmodes The resonant frequencies of the higher eigenmodes were characterized by performing a frequency sweep using

Molecular and mechanical insights into gecko seta adhesion: multiscale simulations combining molecular dynamics and the finite element method

• Yash Jain,
• Saeed Norouzi,
• Tobias Materzok,
• Stanislav N. Gorb and
• Florian Müller-Plathe

Beilstein J. Nanotechnol. 2025, 16, 2055–2076, doi:10.3762/bjnano.16.141

• surface, and a 13 nm thick amorphous bulk below, which matched the same bead density as our previous random-substrate model. All substrate beads had identical interactions with the spatula, and both layers were held fixed in space. Since the regular top monolayer differed from the fully random arrangement

Beyond the shell: exploring polymer–lipid interfaces in core–shell nanofibers to carry hyaluronic acid and β-caryophyllene

• Aline Tavares da Silva Barreto,
• Francisco Alexandrino-Júnior,
• Bráulio Soares Arcanjo,
• Paulo Henrique de Souza Picciani and
• Kattya Gyselle de Holanda e Silva

Beilstein J. Nanotechnol. 2025, 16, 2015–2033, doi:10.3762/bjnano.16.139

• achieved when the relative humidity was below 45% [47]. Regarding the NE-βCp concentration, it was evident that values above 2% (Figure 2B) led to the formation of more heterogeneous fibers with a higher density of beads, likely because the increased droplet content hindered proper flow and elongation of

• to 0.75% HA showed a higher density of beads, suggesting insufficient polymer chain entanglement, which may have impaired fiber stretching during the electrospinning process. Among the tested concentrations, 1.00% HA yielded the most uniform fibers. This effect may result from a more favorable

• density of hydrophilic (carboxyl –COOH and hydroxyl –OH) and catalytic (carboxyl –COOH) end groups in the amorphous regions between crystalline domains. These terminal groups reduce chain packing in the amorphous regions between crystallites, making them less densely packed than amorphous polymers and

The cement of the tube-dwelling polychaete Sabellaria alveolata: a complex composite adhesive material

• Emilie Duthoo,
• Aurélie Lambert,
• Pierre Becker,
• Carla Pugliese,
• Jean-Marc Baele,
• Arnaud Delfairière,
• Matthew J. Harrington and
• Patrick Flammang

Beilstein J. Nanotechnol. 2025, 16, 1998–2014, doi:10.3762/bjnano.16.138

• TEM (Figure 2F,G). The cement matrix is homogeneous and of medium electron density. It encloses hollow spheroids of various sizes, as well as small electron-dense granules and small lacunae (Figure 2F). The exception is the periphery of the cement spot, which is made up entirely of the matrix, giving

• secretory granules, that is, cells with homogeneous granules and cells with heterogeneous granules (Figure 3G,H, Figure 4A,B). Both types of granules have a size between 2.5 and 4.0 μm in diameter. Homogeneous granules have a uniform electron density with no internal structure (Figure 4A,C). In contrast

Laser ablation in liquids for shape-tailored synthesis of nanomaterials: status and challenges

• Natalie Tarasenka

Beilstein J. Nanotechnol. 2025, 16, 1963–1997, doi:10.3762/bjnano.16.137

• mechanism occurs from nano- or microsized droplets or solid fragments directly ejected from the target. The dominating mechanism of NP formation depends on the laser parameters, mainly laser pulse duration and laser fluence. For the nanosecond laser pulse of high energy density (in the range 108–1010 W·cm−2

• ), the thermal evaporation is preferential [1], while for picosecond and femtosecond laser pulses of lower power density, the explosive ejection mechanism typically prevails resulting in NP formation at earlier stages from the ejected droplets or fragments. 1.3 Nanoparticle nucleation and growth After

• is induced due to the difference of charge density at the sharper end of the structure. As a result, the assembly of the droplet-like shapes form organized dendritic structures instead of loose aggregates due to a stronger repulsion by the sharp ends of the nanodroplets as compared to that of the

Quantum circuits with SINIS structures

• Mikhail Tarasov,
• Mikhail Fominskii,
• Aleksandra Gunbina,
• Artem Krasilnikov,
• Maria Mansfeld,
• Dmitrii Kukushkin,
• Andrei Maruhno,
• Valeria Ievleva,
• Mikhail Strelkov,
• Daniil Zhogov,
• Konstantin Arutyunov,
• Vyacheslav Vdovin,
• Vladislav Stolyarov and
• Valerian Edelman

Beilstein J. Nanotechnol. 2025, 16, 1931–1941, doi:10.3762/bjnano.16.134

• current occurs when eV > Δ. In the case when T ≠ 0 the I–V curve will be smeared [22]. The current–voltage characteristic of a tunnel NIS junction is determined by the following formula [23]: where Rn is the asymptotic resistance of the tunnel junction, NS(E) is the density of states in the superconductor

• the charge transfer by electrons during tunneling through the tunnel SIN junction and the thermal noise of these same electrons as heat carriers: δIω2 is the power spectral density (PSD) of current fluctuations due to shot noise, δPω2 is the PSD of thermal fluctuations, and ⟨δPωδIω⟩ is the correlation

• flux density is S = I × Ω = 1677 Jy = 1.677 × 10−23 W·m−2·Hz−1. For 172.6 K at 100 GHz, we have a blackbody intensity I = 5.23 × 10−16 W·m−2·Hz−1·sr−1. The power density collected by a telescope with an effective aperture of 22.6 m2 is P = 3.79 × 10−22 W·Hz−1. The total power in the 10% band recorded

PEGylated lipids in lipid nanoparticle delivery dynamics and therapeutic innovation

• Peiyang Gao

Beilstein J. Nanotechnol. 2025, 16, 1914–1930, doi:10.3762/bjnano.16.133

• chains arrange on the nanoparticle surface and the potential impacts on LNPs’ physicochemical properties by varying surface PEG density or PEG chemistry. Subsequently, PEG conformations are discussed in terms of their modulation of protein corona formation, cellular uptake, and immunogenic responses

• review first reveals the localization and conformation of PEG lipids on the LNP surface, which is fundamental for understanding how PEG lipids contribute to nanoparticle stability and surface interactions. It then demonstrates how PEG density and chemical structure may influence the physicochemical

• lipid surface density and structure on LNP physicochemical properties Understanding the spatial organization of lipid components within LNPs is critical for optimizing their physicochemical characterization and stability. In particular, the localization of PEG lipids plays a significant role in

Programmable soliton dynamics in all-Josephson-junction logic cells and networks

• Vsevolod I. Ruzhickiy,
• Anastasia A. Maksimovskaya,
• Sergey V. Bakurskiy,
• Andrey E. Schegolev,
• Maxim V. Tereshonok,
• Mikhail Yu. Kupriyanov,
• Nikolay V. Klenov and
• Igor I. Soloviev

Beilstein J. Nanotechnol. 2025, 16, 1883–1893, doi:10.3762/bjnano.16.131

• JJ-based architectures face fundamental density constraints imposed by magnetic flux manipulation requirements and complex mutual inductive crosstalks. Circuits composed entirely of Josephson junctions (all-JJ circuits) [10][11][12][13][14][15][16] represent a promising platform for energy-efficient

• compact design and new (diode) functionality of various superconducting computing modules and makes possible further increase of integration density compared to well-known RSFQ technology. (a) An equivalent scheme for the “kinetic inductance controllable key” (KICK) as a part of an all-Josephson

Electrical, photocatalytic, and sensory properties of graphene oxide and polyimide implanted with low- and medium-energy silver ions

• Josef Novák,
• Eva Štěpanovská,
• Petr Malinský,
• Vlastimil Mazánek,
• Jan Luxa,
• Ulrich Kentsch and
• Zdeněk Sofer

Beilstein J. Nanotechnol. 2025, 16, 1794–1811, doi:10.3762/bjnano.16.123

• can further enhance the electrical conductivity of the non-conductive material [11]. These islands can act as conductive bridges between graphitic regions, and, at sufficient density, form a percolating network that significantly reduces resistance. The resulting hybrid system consisting of a

• bandgap and an increased density of states near the Fermi level, promotes absorption in the visible region and facilitates the generation of electron–hole (e−–h+) pairs upon light irradiation. The silver clusters also exhibit plasmonic resonances, which amplify the local electromagnetic field and promote

• calculation was performed through a complex Monte Carlo simulation. The initial GO composition for SRIM simulation was determined by RBS analysis of the pristine sample, while the composition and density of the PI polymer were obtained from the SRIM database. The results of the SRIM simulation are shown in

Exploring the potential of polymers: advancements in oral nanocarrier technology

• Rousilândia de Araujo Silva,
• Igor Eduardo Silva Arruda,
• Luise Lopes Chaves,
• Mônica Felts de La Roca Soares and
• Jose Lamartine Soares Sobrinho

Beilstein J. Nanotechnol. 2025, 16, 1751–1793, doi:10.3762/bjnano.16.122

• -mucoadhesive particles can penetrate the mucus of the small and large intestine, spreading across nearly the entire tissue surface and facilitating drug delivery for systemic applications. This behavior occurs because surface properties influence polymer–mucus interactions, altering the entanglement density of

• the charge properties and the interaction between chitosan and sodium tripolyphosphate (TPP) molecules. At low pH, the amino groups become protonated, causing the molecule to adopt an extended conformation due to charge repulsion. The TPP molecule is also protonated, generating a lower charge density

• . At pH 4, both TPP and chitosan undergo deprotonation, with the protonation of chitosan being less affected, leading to a strong TPP–chitosan interaction that prevents rifampicin release. Conversely, at basic pH, the increased TPP charge neutralizes the charge density in chitosan, causing the collapse

Multifunctional anionic nanoemulsion with linseed oil and lecithin: a preliminary approach for dry eye disease

• Niédja Fittipaldi Vasconcelos,
• Almerinda Agrelli,
• Rayane Cristine Santos da Silva,
• Carina Lucena Mendes-Marques,
• Isabel Renata de Souza Arruda,
• Priscilla Stela Santana de Oliveira,
• Mércia Liane de Oliveira and
• Giovanna Machado

Beilstein J. Nanotechnol. 2025, 16, 1711–1733, doi:10.3762/bjnano.16.120

• and density The viscosity and density of LO were measured using an SVM 3000/G2 kinematic viscometer (Anton Paar, USA). The measurements were performed at two temperatures: 25 °C (by ASTM D7042-21 standard) and 75 °C, with each measurement repeated in triplicate to determine the mean ± standard

• health [65][66]. PUFAs are well-known for their therapeutic potential, particularly their anti-inflammatory and antioxidant properties [30], showing promising results in systemic and topical treatment [33][67][68], including for dry eye disease [35][36][69]. The viscosity, density, and AV of LO at both

• room temperature (25 °C) and elevated temperature (75 °C) are summarized in Table 2. Visually, heating LO to 75 °C did not result in any noticeable changes in color or turbidity; the oil maintained its original yellowish hue and translucent appearance, as shown in Figure 1a. The observed density of LO

Ambient pressure XPS at MAX IV

• Mattia Scardamaglia,
• Ulrike Küst,
• Alexander Klyushin,
• Rosemary Jones,
• Jan Knudsen,
• Robert Temperton,
• Andrey Shavorskiy and
• Esko Kokkonen

Beilstein J. Nanotechnol. 2025, 16, 1677–1694, doi:10.3762/bjnano.16.118

• precious metals such as Rh, Pd, and Pt [14][15]. Their atom-level dispersion maximizes surface exposure and minimizes metal consumption, which is critical for both economic and environmental sustainability. However, their inherently low site density and metastability under reaction conditions present

Energy spectrum and quantum phase transition of the coupled single spin and an infinitely coordinated Ising chain

• Seidali Seidov,
• Natalia Pugach and
• Anatolie Sidorenko

Beilstein J. Nanotechnol. 2025, 16, 1668–1676, doi:10.3762/bjnano.16.117

• the single-spin density matrix. One might choose to make or not to make the Markov approximation, obtaining different types of master equations. Given that the exact solution is known, different master equation solutions can be compared against it. This allows to study the limits of applicability of

Prospects of nanotechnology and natural products for cancer and immunotherapy

• Jan Filipe Andrade Santos,
• Marcela Bernardes Brasileiro,
• Pamela Danielle Cavalcante Barreto,
• Ligiane Aranha Rocha and
• José Adão Carvalho Nascimento Júnior

Beilstein J. Nanotechnol. 2025, 16, 1644–1667, doi:10.3762/bjnano.16.116

• polymeric membranes, non-ionic surfactants, macromolecules, and phospholipids [176][177]. The properties of the pharmaceutical form are governed by size, shape, core structure, and ligands, which can alter factors such as solubility, charge density, hydrophobicity, stability, and binding affinity [178]. The

Venom-loaded cationic-functionalized poly(lactic acid) nanoparticles for serum production against Tityus serrulatus scorpion

• Philippe de Castro Mesquita,
• Karla Samara Rocha Soares,
• Manoela Torres-Rêgo,
• Emanuell dos Santos-Silva,
• Mariana Farias Alves-Silva,
• Alianda Maira Cornélio,
• Matheus de Freitas Fernandes-Pedrosa and
• Arnóbio Antônio da Silva-Júnior

Beilstein J. Nanotechnol. 2025, 16, 1633–1643, doi:10.3762/bjnano.16.115

• cationic nanoparticles prepared by ionic gelation with 100% encapsulation efficiency [1][2]. Additionally, PEI with high branching density has been shown to enhance complexation and transfection efficiency [23]. The morphology obtained by AFM and FEGSEM showed particles with a smooth surface, spherical

Nanotechnology-based approaches for the removal of microplastics from wastewater: a comprehensive review

• Nayanathara O Sanjeev,
• Manjunath Singanodi Vallabha and
• Rebekah Rubidha Lisha Rabi

Beilstein J. Nanotechnol. 2025, 16, 1607–1632, doi:10.3762/bjnano.16.114

• wear, and microbial activity [3]. Common types of MPs found in ecosystems, particularly in freshwater and drinking water sources, include materials such as high-density polyethylene, polystyrene, polyvinyl chloride, and polypropylene [4]. Among the various contributors to MPs, residential households

• hydrocarbons, heavy metals, and other toxic contaminants, increasing their potential risks to living ecosystems and organisms [9][10]. MPs have low density, variable sizes, high persistence, and non-biodegradable nature. These characteristics make their removal difficult, especially in aquatic environments [11

• low density are present initially in the suspended form. However, as time passes, they interact with suspended clay particles, and an accumulation of biofilm occurs, resulting in an increase in density. This will result in gradual settlement of the MPs in the sediment [19]. The concentration of MPs in

Bioinspired polypropylene-based functionally graded materials and metamaterials modeling the mistletoe–host interface

• Lina M. Rojas González,
• Naeim Ghavidelnia,
• Christoph Eberl and
• Max D. Mylo

Beilstein J. Nanotechnol. 2025, 16, 1592–1606, doi:10.3762/bjnano.16.113

•  4A shows representative cross-sectional μCT images for each scan. The relatively small difference in brightness between the PP matrix (dark grey) and the surrounding air (black) compared to the very bright appearing glass fibers can be explained by the large difference in density between the polymer

• number of burnt glass fiber particles at the edges. In the sections with the highest glass fiber density, a volume fraction of between 25% and 30% was obtained, which is in good agreement with the 25% specified by the manufacturer (Figure 4D), demonstrating the validity of the fiber content analysis

• locations. For example, DIC showed a wider strain distribution for the specimens with a V-shaped interface, but all specimens failed in the area with the highest glass fiber density. This makes it possible to introduce predetermined failure points into material systems and program the stiffness and local

Few-photon microwave fields for superconducting transmon-based qudit control

• Irina A. Solovykh,
• Andrey V. Pashchenko,
• Natalya A. Maleeva,
• Nikolay V. Klenov,
• Olga V. Tikhonova and
• Igor I. Soloviev

Beilstein J. Nanotechnol. 2025, 16, 1580–1591, doi:10.3762/bjnano.16.112

• application of the rotating wave approximation, which makes it possible to use the relation in Equation 5, are Δω ≪ ω0 and g ≪ ω0 [44]. Here, the efficiency of the interaction between two subsystems is determined by the average photon density ⟨N⟩/Vres, which is large enough to allow field-induced transitions

• regulated by the interferometric arm asymmetry, and the values of EJ determine the magnitude of the critical current and the area of each JJ: Ic1 ≈ 39.44 nA, S1 = 200 × 197 nm2, Ic2 ≈ 22.21 nA, and S2 = 149 × 149 nm2, with the usual critical current density of j = 1 μA·μm−2. The frequency of the resonator

Modeling magnetic properties of cobalt nanofilms used as a component of spin hybrid superconductor–ferromagnetic structures

• Aleksey Fedotov,
• Olesya Severyukhina,
• Anastasia Salomatina and
• Anatolie Sidorenko

Beilstein J. Nanotechnol. 2025, 16, 1557–1566, doi:10.3762/bjnano.16.110

• particle; and Tl and Ts are values of the thermodynamic and spin temperatures, respectively [26][27]. The potential of the modified embedded atom method [28][29] was based on the electron density functional theory. The magnitude of the potential UMEAM depends on the set of atomic positions, which makes the

• density. When describing the electron density, different types of electron clouds of the atoms under consideration are taken into account, and a sufficiently large set of potential parameters is involved, which makes MEAM sufficiently accurate and allows it to be used in solving a wide range of atomistic

• -monolayers, the number of nearest neighbors for cobalt atoms sharply decreases. This weakens the exchange interaction that stabilizes the ferromagnetic order. Disruption of lattice periodicity and a high density of defects exacerbate this problem. For these reasons, such studies are not included in this

Transient electronics for sustainability: Emerging technologies and future directions

• Jae-Young Bae,
• Myung-Kyun Choi and
• Seung-Kyun Kang

Beilstein J. Nanotechnol. 2025, 16, 1545–1556, doi:10.3762/bjnano.16.109

• stimulators, and drug delivery vehicles, as well as environmentally benign electronics for soil or aquatic disposal. Despite their potential, key challenges remain in expanding the material set for diverse functionalities, achieving high-density integration for advanced operations, and enabling precise

• identifies three central areas that warrant focused development. First, the expansion of the available materials palette is essential to support diverse electronic functionalities. Second, advancements in high-density integration techniques are required to realize sophisticated, multifunctional devices

• plugs, ~100 nm). The fabricated single unit of n-channel MOSFETs exhibits on/off current ratios exceeding 107 and field-effect mobilities up to 680 cm2·V−1·s−1 [80]. This approach is considered key for realizing the high-density integration and mass production of bioresorbable systems. Looking beyond

Influence of laser beam profile on morphology and optical properties of silicon nanoparticles formed by laser ablation in liquid

• Natalie Tarasenka,
• Vladislav Kornev,
• Alena Nevar and
• Nikolai Tarasenko

Beilstein J. Nanotechnol. 2025, 16, 1533–1544, doi:10.3762/bjnano.16.108

• ablation synthesis of nanomaterials in liquids are still very rare. A typical PLAL experiment uses a Gaussian beam profile, which is known to have a tight focus along both transverse and propagation axes and the highest power density in the beam center. Non-Gaussian beam profiles are characterized by a non

• potential wells and can result in confinement of plasma and CB propagation, CB oscillations, and the reflection of shockwaves [29]. The confinement and reflection effects are known to result in a plasma compression and, consequently, plasma temperature and electron density increase [35][36][37]. A reflected

• shockwave also causes perturbations in the medium, thus, influencing the electron density distribution in the plasma. Furthermore, the confinement of the plasma plume slows down thermalization and cooling of the plasma, changing the conditions for the nucleation and growth of the nanoparticles [37]. The

Cross-reactivities in conjugation reactions involving iron oxide nanoparticles

• Shoronia N. Cross,
• Katalin V. Korpany,
• Hanine Zakaria and
• Amy Szuchmacher Blum

Beilstein J. Nanotechnol. 2025, 16, 1504–1521, doi:10.3762/bjnano.16.106

• steric hindrance, as well as to deactivation of the amine through withdrawal of electron density. We suspect that the latter is the most important factor affecting the poor reactivity of these dyes, as attempts to perform the EDC/NHS coupling in DMF, DMSO, and EtOH, wherein the dyes are much more soluble

• lineshape for the IONP-CySS/DTT, which suggests the presence of multiple binding sites, resulting in an increased Cy3 packing density, thereby enabling H-aggregate formation. This observation provides evidence that there is successful cleavage of the disulfide bonds, when treated with DTT, resulting in Cy3

• -exposed to bind Cy3-maleimide. We reason that, while the DTT molecule can reach the IONP surface and bind through one of its thiols, the density of DHBA ligands is such that it is not likely that the DTT molecule will fold over and bind to surface Fe through the remaining SH group at the opposite end of

Laser processing in liquids: insights into nanocolloid generation and thin film integration for energy, photonic, and sensing applications

• Akshana Parameswaran Sreekala,
• Pooja Raveendran Nair,
• Jithin Kundalam Kadavath,
• Bindu Krishnan,
• David Avellaneda Avellaneda,
• M. R. Anantharaman and
• Sadasivan Shaji

Beilstein J. Nanotechnol. 2025, 16, 1428–1498, doi:10.3762/bjnano.16.104

• characteristics, are influenced by the NP size and crystalline quality (Figure 3b,c). LFL also plays a crucial role in tuning the optical properties of NPs. Laser processing affects the defect density and optical bandgap of the particles, as demonstrated by changes in the optical transmission spectra before and

• parameters, researchers have been able to selectively create and stabilize the desired type and distribution of defects within the electrode materials, leading to improvements in energy density, power density, and cycling stability of electrochemical energy storage devices [88][89][90][91]. Furthermore, LDL

• experimental setup for LDL typically involves a tightly focused laser beam interacting with a liquid precursor or solution. This precise control over the laser parameters, including wavelength, pulse duration, and energy density, allows researchers to carefully tailor the nature and distribution of the