Search results

Search for "drug delivery" in Full Text gives 329 result(s) in Beilstein Journal of Nanotechnology. Showing first 200.

Liver-targeting iron oxide nanoparticles and their complexes with plant extracts for biocompatibility

  • Shushanik A. Kazaryan,
  • Seda A. Oganian,
  • Gayane S. Vardanyan,
  • Anatolie S. Sidorenko and
  • Ashkhen A. Hovhannisyan

Beilstein J. Nanotechnol. 2024, 15, 1593–1602, doi:10.3762/bjnano.15.125

Graphical Abstract
  • (Fe3O4 NPs) are widely used in many biomedical applications (e.g., bioimaging, drug delivery, biosensors, diagnostics, and theranostics). However, the use of NPs does not preclude the possibility of selective toxicity and undesirable effects, including accumulation in tissues and direct interaction with
  • , biochemistry, biophysics, and other disciplines within biology and medicine [1][2][3][4][5]. The development of nanotechnology has provided resources for various applications in the medical field, leading to significant advances in diagnosis, biological detection, therapy, and drug delivery [6][7][8][9]. An
PDF
Album
Full Research Paper
Published 11 Dec 2024

The round-robin approach applied to nanoinformatics: consensus prediction of nanomaterials zeta potential

  • Dimitra-Danai Varsou,
  • Arkaprava Banerjee,
  • Joyita Roy,
  • Kunal Roy,
  • Giannis Savvas,
  • Haralambos Sarimveis,
  • Ewelina Wyrzykowska,
  • Mateusz Balicki,
  • Tomasz Puzyn,
  • Georgia Melagraki,
  • Iseult Lynch and
  • Antreas Afantitis

Beilstein J. Nanotechnol. 2024, 15, 1536–1553, doi:10.3762/bjnano.15.121

Graphical Abstract
  • ; read-across; QSPR; round-robin test; zeta potential; Introduction Nanotechnology, defined as the ability to manipulate matter at the nanoscale, has opened an array of possibilities for multiple applications that take advantage of the unique properties of nanomaterials (NMs). From targeted drug
  • delivery to environmental sensing, the versatility of NMs makes them ideal candidates for a broad range of innovative applications [1]. However, the complexity and unique properties of these materials also present significant challenges, especially when it comes to the assessment of their potential adverse
PDF
Album
Supp Info
Full Research Paper
Published 29 Nov 2024

Polymer lipid hybrid nanoparticles for phytochemical delivery: challenges, progress, and future prospects

  • Iqra Rahat,
  • Pooja Yadav,
  • Aditi Singhal,
  • Mohammad Fareed,
  • Jaganathan Raja Purushothaman,
  • Mohammed Aslam,
  • Raju Balaji,
  • Sonali Patil-Shinde and
  • Md. Rizwanullah

Beilstein J. Nanotechnol. 2024, 15, 1473–1497, doi:10.3762/bjnano.15.118

Graphical Abstract
  • core with a stable outer lipoidal shell makes these PLHNPs an excellent nanocarrier for therapeutic drug delivery and the treatment of various diseases. The amphiphilicity of biodegradable polymers and lipids promotes the encapsulation of both lipophilic as well as hydrophilic chemotherapeutic drugs
  • yields a natural vehicle for drug delivery, and these nanocarriers can easily escape the uptake by macrophages. In this system, the drugs are encapsulated in the lipophilic polymeric core, and the lipids in the outer natural membrane enhance the sustained release of drugs. With the development of these
  • hybrid nanocarriers, the biological barriers in therapeutic drug delivery can be easily overcome. These hybrid nanocarriers show prolonged half-life and stability in biological systems, thereby enhancing therapeutic efficacy [58][59]. Surface modification of PLHNPs Surface modification of PLHNPs involves
PDF
Album
Review
Published 22 Nov 2024

Nanotechnological approaches for efficient N2B delivery: from small-molecule drugs to biopharmaceuticals

  • Selin Akpinar Adscheid,
  • Akif E. Türeli,
  • Nazende Günday-Türeli and
  • Marc Schneider

Beilstein J. Nanotechnol. 2024, 15, 1400–1414, doi:10.3762/bjnano.15.113

Graphical Abstract
  • drugs can be encapsulated into various drug delivery systems to enhance physicochemical characteristics and targeting success. Many preclinical data show that this strategy can effectively deliver biopharmaceuticals to the brain. Therefore, this review focuses on N2B delivery while giving examples of
  • different drug delivery systems suitable for the applications. In addition, we emphasize the importance of the effective delivery of monoclonal antibodies and RNA and stress the recent literature tackling this challenge. While giving examples of nanotechnological approaches for the effective delivery of
  • small or large molecules from the current literature, we highlight the preclinical studies and their results to prove the strategies’ success and limitations. Keywords: antibody delivery; biopharmaceutical delivery; blood–brain barrier (BBB); CNS diseases; drug delivery; hybrid nanoparticles
PDF
Album
Review
Published 12 Nov 2024

Hymenoptera and biomimetic surfaces: insights and innovations

  • Vinicius Marques Lopez,
  • Carlo Polidori and
  • Rhainer Guillermo Ferreira

Beilstein J. Nanotechnol. 2024, 15, 1333–1352, doi:10.3762/bjnano.15.107

Graphical Abstract
  • biodiversity, and assessing environmental impacts, providing researchers with valuable data while preserving natural habitats. Delivery systems: Strength and efficiency of the ovipositor also offer insights into creating advanced drug delivery systems [169]. These systems can deliver medications directly to
  • delivery system (Figure 7C,D). The venom delivery systems of Hymenoptera are precise and efficient, inspiring the design of microinjection systems and targeted drug delivery methods that minimize collateral damage to surrounding tissues [170]. Drawing inspiration from the precision and efficiency of
  • could greatly benefit from innovations inspired by these stridulation mechanisms. Ultrasound technology has demonstrated significant potential in diagnostic imaging and ultrasound-responsive drug delivery [181][182]. Ultrasound technology is particularly promising for cancer treatment and disease
PDF
Album
Review
Published 05 Nov 2024

Enhanced catalytic reduction through in situ synthesized gold nanoparticles embedded in glucosamine/alginate nanocomposites

  • Chi-Hien Dang,
  • Le-Kim-Thuy Nguyen,
  • Minh-Trong Tran,
  • Van-Dung Le,
  • Nguyen Minh Ty,
  • T. Ngoc Han Pham,
  • Hieu Vu-Quang,
  • Tran Thi Kim Chi,
  • Tran Thi Huong Giang,
  • Nguyen Thi Thanh Tu and
  • Thanh-Danh Nguyen

Beilstein J. Nanotechnol. 2024, 15, 1227–1237, doi:10.3762/bjnano.15.99

Graphical Abstract
  • ) and the cross-linker [17]. These materials find wide applications in drug delivery [18] and the encapsulation of nanometals [19][20]. Reduction of metallic ions can be achieved using various agents, including plant extracts [21]. This reduction typically involves two steps, namely, the loading of
PDF
Album
Full Research Paper
Published 04 Oct 2024

Realizing active targeting in cancer nanomedicine with ultrasmall nanoparticles

  • André F. Lima,
  • Giselle Z. Justo and
  • Alioscka A. Sousa

Beilstein J. Nanotechnol. 2024, 15, 1208–1226, doi:10.3762/bjnano.15.98

Graphical Abstract
  • ) designed to transport therapeutic agents with precise delivery to tumor sites. This approach aims to mitigate toxic effects associated with off-target drug delivery and optimize therapeutic efficacy. For decades, the enhanced permeability and retention (EPR) effect has stood as the central mechanism for
  • imaging [20][40], and positron emission tomography [45][46]. In therapeutic applications, usNPs have been used for drug delivery as well as served as phototherapeutic agents and radiosensitizers [47][48][49][50][51]. A distinguishing feature of usNPs is their transient, short-lived interactions with
  • targeting can also promote usNP transport to the cell interior, potentially leading to more effective drug delivery and chemotherapy. It must be noted that the success of these strategies relies on efficient passive targeting in the first place [83][84]. Nevertheless, cumulative evidence suggests that
PDF
Album
Review
Published 30 Sep 2024

Synthesis, characterization and anticancer effect of doxorubicin-loaded dual stimuli-responsive smart nanopolymers

  • Ömür Acet,
  • Pavel Kirsanov,
  • Burcu Önal Acet,
  • Inessa Halets-Bui,
  • Dzmitry Shcharbin,
  • Şeyda Ceylan Cömert and
  • Mehmet Odabaşı

Beilstein J. Nanotechnol. 2024, 15, 1189–1196, doi:10.3762/bjnano.15.96

Graphical Abstract
  • extremely useful for drug delivery and release. We analyzed the possibility to include the known antitumor drug doxorubicin (DOX), which has antimitotic and antiproliferative effects, in a nanopolymer complex. Thus, doxorubicin-loaded temperature- and pH-sensitive smart nanopolymers (DOX-SNPs) were produced
  • that observed for the commercial liposomal formulation of doxorubicin Doxil. The obtained results demonstrated that smart nanopolymers can be efficiently used to create new types of doxorubicin-based drugs. Keywords: cancer cell line HeLa; cytotoxicity; doxorubicin; drug delivery; smart nanopolymers
  • , high stability, low toxicity, modifiable hydrophilicity/hydrophobicity, and the possibility of surface functionalization for targeted localization. Polymeric nanoparticles are a versatile approach to drug delivery (DD) with the potential to circumvent barriers associated with negative impacts on
PDF
Album
Full Research Paper
Published 26 Sep 2024

AI-assisted models to predict chemotherapy drugs modified with C60 fullerene derivatives

  • Jonathan-Siu-Loong Robles-Hernández,
  • Dora Iliana Medina,
  • Katerin Aguirre-Hurtado,
  • Marlene Bosquez,
  • Roberto Salcedo and
  • Alan Miralrio

Beilstein J. Nanotechnol. 2024, 15, 1170–1188, doi:10.3762/bjnano.15.95

Graphical Abstract
  • , central nervous system and cardiac disorders, and autoimmune diseases [16]. In recent years, nanomaterials have attracted the attention of different scientific communities by providing them with new solutions for drug delivery [19][20]. These nanotechnological applications have made it possible to obtain
  • treatments that release substances at specific sites of interest, reducing the required drug amount and side effects. Nanostructures to form these drug delivery systems can be divided into organic and inorganic [19][20], with the latter one being the less extensively studied. One option currently considered
PDF
Album
Supp Info
Full Research Paper
Published 19 Sep 2024

Introducing third-generation periodic table descriptors for nano-qRASTR modeling of zebrafish toxicity of metal oxide nanoparticles

  • Supratik Kar and
  • Siyun Yang

Beilstein J. Nanotechnol. 2024, 15, 1142–1152, doi:10.3762/bjnano.15.93

Graphical Abstract
  • development of nanotechnology, more and more MONPs including zinc, iron, titanium, and copper are being explored in therapeutic applications such as drug delivery, bioimaging, biosensing, bioelectronics, and tissue engineering applications [4][5][6]. Simultaneously, many of these particles also presented
  • findings of this study have significant implications for the use of MONPs in medical applications. Nanoparticles are increasingly explored regarding drug delivery, imaging, and therapeutic purposes. Understanding the toxicity mechanisms and predicting potential adverse effects of MONPs can guide the design
PDF
Album
Supp Info
Full Research Paper
Published 10 Sep 2024

Recent updates in applications of nanomedicine for the treatment of hepatic fibrosis

  • Damai Ria Setyawati,
  • Fransiska Christydira Sekaringtyas,
  • Riyona Desvy Pratiwi,
  • A’liyatur Rosyidah,
  • Rohimmahtunnissa Azhar,
  • Nunik Gustini,
  • Gita Syahputra,
  • Idah Rosidah,
  • Etik Mardliyati,
  • Tarwadi and
  • Sjaikhurrizal El Muttaqien

Beilstein J. Nanotechnol. 2024, 15, 1105–1116, doi:10.3762/bjnano.15.89

Graphical Abstract
  • played an important role in the enhancement of therapeutic outcomes compared to those of conventional therapy. At the same time, nanoparticle drug delivery systems offer a significant reduction in side effects of treatments by lowering the off-target biodistribution of the active pharmaceutical
  • fibrosis. We first emphasize the challenges of conventional drugs for penetrating the biological barriers of the liver. After that, we highlight design principles of nanocarriers for achieving improved drug delivery of antifibrosis drugs through passive and active targeting strategies. Keywords: active
  • application of nanoscale systems with unique physicochemical properties, including small size, large specific surface area, high reactivity, and quantum effects of the nanoparticles (NPs) [1][2]. Nanomedicine is specifically designated for therapeutics (drug delivery), diagnostics, and imaging, as well as for
PDF
Album
Review
Published 23 Aug 2024

Unveiling the potential of alginate-based nanomaterials in sensing technology and smart delivery applications

  • Shakhzodjon Uzokboev,
  • Khojimukhammad Akhmadbekov,
  • Ra’no Nuritdinova,
  • Salah M. Tawfik and
  • Yong-Ill Lee

Beilstein J. Nanotechnol. 2024, 15, 1077–1104, doi:10.3762/bjnano.15.88

Graphical Abstract
  • and pharmaceutical fields. Many review papers describe applications of alginate in the drug delivery field. The current study covers the structural and physicochemical properties of alginate-based nanoparticles. The prospective applications of alginate-based nanomaterials in various domains are
  • discussed, including drug delivery and environmental sensing applications for humidity, heavy metals, and hydrogen peroxide. Moreover, biomedical sensing applications of alginate-based nanoparticles regarding various analytes such as glucose, cancer cells, pharmaceutical drugs, and human motion will also be
  • reviewed in this paper. Future research scopes highlight existing challenges and solutions. Keywords: alginate; biomedical sensing; polymer nanoparticle; smart drug delivery; Review Introduction Sensors have received a lot of attention in a variety of applications, including health, pharmacy, the
PDF
Album
Review
Published 22 Aug 2024

Interface properties of nanostructured carbon-coated biological implants: an overview

  • Mattia Bartoli,
  • Francesca Cardano,
  • Erik Piatti,
  • Stefania Lettieri,
  • Andrea Fin and
  • Alberto Tagliaferro

Beilstein J. Nanotechnol. 2024, 15, 1041–1053, doi:10.3762/bjnano.15.85

Graphical Abstract
  • applications [4] as active species or as drug delivery platforms using tailored carbon nanotubes (CNTs) [5][6], fullerenes [7][8], carbon dots (CDs) [9][10], and graphene-related materials (i.e., graphene oxide (GO) [11], reduced graphene oxide (rGO) [12], and nanographite (nG) [13]). Furthermore, the
PDF
Album
Review
Published 16 Aug 2024

Entry of nanoparticles into cells and tissues: status and challenges

  • Kirsten Sandvig,
  • Tore Geir Iversen and
  • Tore Skotland

Beilstein J. Nanotechnol. 2024, 15, 1017–1029, doi:10.3762/bjnano.15.83

Graphical Abstract
  • , exposure to various types of NPs (Au, Ag, SiO2, and Fe3O4) was found to change the content of EV-containing miRNAs [72]. It is important to understand the mechanisms involved to analyze exosome markers with and without incubation with NPs. Nanoparticles under development for drug delivery are made from
  • -based products for drug delivery into the cytosol is whether sufficient drug is delivered when not benefitting from the cytosolic amplification as in the case of mRNA. Another issue that needs attention regarding the use of such lipid-based NPs for drug delivery is whether ionizable synthetic lipids
PDF
Album
Perspective
Published 12 Aug 2024

Therapeutic effect of F127-folate@PLGA/CHL/IR780 nanoparticles on folate receptor-expressing cancer cells

  • Thi Ngoc Han Pham,
  • Phuong-Thao Dang-Luong,
  • Hong-Phuc Nguyen,
  • Loc Le-Tuan,
  • Xuan Thang Cao,
  • Thanh-Danh Nguyen,
  • Vy Tran Anh and
  • Hieu Vu_Quang

Beilstein J. Nanotechnol. 2024, 15, 954–964, doi:10.3762/bjnano.15.78

Graphical Abstract
  • ). Previous research has demonstrated that the presence of folate on the particles increases the internalization of the nanoparticles into the cell [12][14][36][37]. Many studies have used F127 as a drug delivery agent because it is an FDA-approved material for use in the living body and assists the entry of
PDF
Album
Supp Info
Full Research Paper
Published 31 Jul 2024

Electrospun nanofibers: building blocks for the repair of bone tissue

  • Tuğrul Mert Serim,
  • Gülin Amasya,
  • Tuğba Eren-Böncü,
  • Ceyda Tuba Şengel-Türk and
  • Ayşe Nurten Özdemir

Beilstein J. Nanotechnol. 2024, 15, 941–953, doi:10.3762/bjnano.15.77

Graphical Abstract
  • regeneration and give an insight about bone regeneration, production techniques of the electrospun nanofibers, and varying formulation parameters in order to reach different drug delivery goals. This review also provides an extensive market research of electrospun nanofibers and an overview on scientific
  • research and patents in the field. Keywords: bone regeneration; controlled release; drug delivery; electrospinning; nanofibers; Introduction The nanofiber technology is a recent technology developed for producing implantable systems that can be used for structural support to the bones as well as drug
  • , antibiotics, anticancer agents, proteins, DNA, RNA, and growth factors for tissue regeneration [6][7][8]. In addition, nanofibers as drug delivery systems provide rapid or delayed and controlled release of pharmaceuticals. Apart from being implantable drug delivery systems, nanofiber scaffolds can contribute
PDF
Album
Review
Published 25 Jul 2024

When nanomedicines meet tropical diseases

  • Eder Lilia Romero,
  • Katrien Van Bocxlaer and
  • Fabio Rocha Formiga

Beilstein J. Nanotechnol. 2024, 15, 830–832, doi:10.3762/bjnano.15.69

Graphical Abstract
  • ]. Potentially beneficial properties of nanomedicines include enhanced drug solubility, improved bioavailability, targeted drug delivery, longer half-life, and reduced toxicity. This thematic issue covers pre-clinical research employing chemotherapeutic or prophylactic nanomedicines against NTDs in a concise
PDF
Editorial
Published 08 Jul 2024

Synthesis of silver–palladium Janus nanoparticles using co-sputtering of independent sources: experimental and theorical study

  • Maria J. Martínez-Carreón,
  • Francisco Solís-Pomar,
  • Abel Fundora,
  • Claudio D. Gutiérrez-Lazos,
  • Sergio Mejía-Rosales,
  • Hector N. Fernández-Escamilla,
  • Jonathan Guerrero-Sánchez,
  • Manuel F. Meléndrez and
  • Eduardo Pérez-Tijerina

Beilstein J. Nanotechnol. 2024, 15, 808–816, doi:10.3762/bjnano.15.67

Graphical Abstract
  • not have. For instance, the distinct sides of Janus nanoparticles can be functionalized with different surface chemistries, allowing for controlled interactions with different molecules, surfaces, or biological entities; this feature may be particularly useful in applications as diverse as drug
  • delivery, catalysis, and sensors. The methodologies, developed for the first time in 1999 [1], for the production of bimetallic nanoparticles in the gas phase can be roughly classified as either simultaneous or sequential. In the first category, the materials that will be used to make the nanoparticles are
PDF
Album
Full Research Paper
Published 04 Jul 2024

Electrospun polysuccinimide scaffolds containing different salts as potential wound dressing material

  • Veronika Pálos,
  • Krisztina S. Nagy,
  • Rita Pázmány,
  • Krisztina Juriga-Tóth,
  • Bálint Budavári,
  • Judit Domokos,
  • Dóra Szabó,
  • Ákos Zsembery and
  • Angela Jedlovszky-Hajdu

Beilstein J. Nanotechnol. 2024, 15, 781–796, doi:10.3762/bjnano.15.65

Graphical Abstract
  • )/hydroxyapatite in orthopedics [1][2]. Biocompatible polymers are widely used in biomedical fields, such as stents, drug delivery systems in cancer therapy, bone repair, dentistry, joint prostheses, and tissue engineering [2][3][4][5][6]. Polymers have several advantageous properties for these applications as
  • created and used in numerous biomedical applications, such as tissue engineering, wound dressing, and drug delivery [11][12]. Electrospinning has many advantages: it is a simple technique, cost-effective, reproducible, scalable, and reliable. In addition, various polymers can be used as starting material
PDF
Album
Supp Info
Full Research Paper
Published 02 Jul 2024

Green synthesis of biomass-derived carbon quantum dots for photocatalytic degradation of methylene blue

  • Dalia Chávez-García,
  • Mario Guzman,
  • Viridiana Sanchez and
  • Rubén D. Cadena-Nava

Beilstein J. Nanotechnol. 2024, 15, 755–766, doi:10.3762/bjnano.15.63

Graphical Abstract
  • of CQDs range from sensing and cell imaging to drug delivery, photocatalysis, and energy conversion [26][27][28][29]. In this study, biomass from watermelon shell and grape pomace waste is used as the carbon source. The hydrothermal method employing urea, nitric acid, and water is utilized. Samples
  • properties for advanced photocatalytic applications. Furthermore, the assessment of luminescence activity unveiled the potential of CQDs for biomedical imaging, particularly with upconversion luminescence. This presents opportunities for targeted cell identification and drug delivery. This study underscores
PDF
Album
Full Research Paper
Published 25 Jun 2024

On the additive artificial intelligence-based discovery of nanoparticle neurodegenerative disease drug delivery systems

  • Shan He,
  • Julen Segura Abarrategi,
  • Harbil Bediaga,
  • Sonia Arrasate and
  • Humberto González-Díaz

Beilstein J. Nanotechnol. 2024, 15, 535–555, doi:10.3762/bjnano.15.47

Graphical Abstract
  • drugs (NDDs) requires immediate attention. Nanoparticle (NP) systems are of increasing interest for transporting NDDs to the central nervous system. However, discovering effective nanoparticle neuronal disease drug delivery systems (N2D3Ss) is challenging because of the vast number of combinations of NP
  • serve as valuable tools in the design of drug delivery systems for neurosciences. Keywords: artificial neural network (ANN); linear discriminant analysis (LDA); machine learning; nanoparticle; neurodegenerative diseases; Introduction Over time, there has been a significant shift in global dietary
  • possible nanomedicine strategies for NDD transport to the central nervous system (CNS) [9][10]. For simplicity, we are going to call them nanoparticle neuronal diseases drug delivery systems (N2D3Ss). N2D3Ss have the ability to protect NDDs from chemical and enzymatic degradation, direct the active
PDF
Album
Supp Info
Full Research Paper
Published 15 May 2024

Cholesterol nanoarchaeosomes for alendronate targeted delivery as an anti-endothelial dysfunction agent

  • Horacio Emanuel Jerez,
  • Yamila Roxana Simioni,
  • Kajal Ghosal,
  • Maria Jose Morilla and
  • Eder Lilia Romero

Beilstein J. Nanotechnol. 2024, 15, 517–534, doi:10.3762/bjnano.15.46

Graphical Abstract
  • interest in the drug delivery field [27][28]. Nanoarchaeosomes (nanoARC) prepared with lipids extracted from H. tebenquichense, for example, are naturally targeted to scavenger receptor A I/II (SRAI/II) expressed by phagocytic cells and certain endothelial cells and outperform liposomes in structural
PDF
Album
Supp Info
Full Research Paper
Published 13 May 2024

Aero-ZnS prepared by physical vapor transport on three-dimensional networks of sacrificial ZnO microtetrapods

  • Veaceslav Ursaki,
  • Tudor Braniste,
  • Victor Zalamai,
  • Emil Rusu,
  • Vladimir Ciobanu,
  • Vadim Morari,
  • Daniel Podgornii,
  • Pier Carlo Ricci,
  • Rainer Adelung and
  • Ion Tiginyanu

Beilstein J. Nanotechnol. 2024, 15, 490–499, doi:10.3762/bjnano.15.44

Graphical Abstract
  • pollutants from the atmosphere and from water, in other catalytic processes, including photocatalytic water splitting, in energy production and storage, in microfluidic systems, in drug delivery and other biomedical applications, in sensing, in electronic, photoelectronic, optoelectronic and nanophotonic
PDF
Album
Full Research Paper
Published 02 May 2024

Fabrication of nanocrystal forms of ᴅ-cycloserine and their application for transdermal and enteric drug delivery systems

  • Hsuan-Ang Tsai,
  • Tsai-Miao Shih,
  • Theodore Tsai,
  • Jhe-Wei Hu,
  • Yi-An Lai,
  • Jui-Fu Hsiao and
  • Guochuan Emil Tsai

Beilstein J. Nanotechnol. 2024, 15, 465–474, doi:10.3762/bjnano.15.42

Graphical Abstract
  • showed good performance in the Franz diffusion test and rodent pharmacokinetic studies due to the nanoparticle size and faster dissolution as compared with the commercial DCS powder. These DCS nanocrystal formulations could offer a new approach for the development of an advanced drug delivery system for
  • the treatment of CNS disorders. Keywords: ᴅ-cycloserine; drug delivery system; enteric capsules; N-methyl-ᴅ-aspartate; nanocrystals; NMDA receptor agonist; transdermal reservoir; Introduction Tuberculosis (TB) is a prevalent respiratory disease caused by Mycobacterium tuberculosis. According to the
  • ]. Nanocrystals can improve many physicochemical properties of drugs such as solubility, size effect, dissolution rate, and adhesiveness to surface membranes [23]. The limitations of conventional medication delivery can be overcome by advanced drug delivery methodologies, such as transdermal drug delivery (TDD
PDF
Album
Full Research Paper
Published 25 Apr 2024

Classification and application of metal-based nanoantioxidants in medicine and healthcare

  • Nguyen Nhat Nam,
  • Nguyen Khoi Song Tran,
  • Tan Tai Nguyen,
  • Nguyen Ngoc Trai,
  • Nguyen Phuong Thuy,
  • Hoang Dang Khoa Do,
  • Nhu Hoa Thi Tran and
  • Kieu The Loan Trinh

Beilstein J. Nanotechnol. 2024, 15, 396–415, doi:10.3762/bjnano.15.36

Graphical Abstract
  • atherosclerotic plaques [171]. One promising avenue involves the development of metal-based NPs for targeted drug delivery to atherosclerotic lesions. These NPs, often composed of biocompatible metals such as gold, silver, or iron, offer unique properties that enable precise drug delivery to affected areas while
  • et al. demonstrated that biodegradable Mg scaffolds have shown promise in promoting vascular regeneration [188]. In brief, the use of metal-based nanomaterials in CVD treatment encompasses a range of innovative approaches from targeted drug delivery using NPs to the development of advanced metallic
PDF
Album
Review
Published 12 Apr 2024
Other Beilstein-Institut Open Science Activities