Design of a nanostructured mucoadhesive system containing curcumin for buccal application: from physicochemical to biological aspects

• Sabrina Barbosa de Souza Ferreira,
• Gustavo Braga,
• Évelin Lemos Oliveira,
• Jéssica Bassi da Silva,
• Hélen Cássia Rosseto,
• Lidiane Vizioli de Castro Hoshino,
• Mauro Luciano Baesso,
• Wilker Caetano,
• Craig Murdoch,
• Helen Elizabeth Colley and
• Marcos Luciano Bruschi

Beilstein J. Nanotechnol. 2019, 10, 2304–2328, doi:10.3762/bjnano.10.222

• . Thus, the most diluted system (0.3%, w/w) showed a significantly higher micelle size and PDI (p < 0.05), probably due to the presence of water, which can enable higher hydration of the polymeric chains. The presence of CUR significantly reduced the PDI (p < 0.05) for the system diluted at 0.3% (w/w

Ion mobility and material transport on KBr in air as a function of the relative humidity

• Dominik J. Kirpal,
• Korbinian Pürckhauer,
• Alfred J. Weymouth and
• Franz J. Giessibl

Beilstein J. Nanotechnol. 2019, 10, 2084–2093, doi:10.3762/bjnano.10.203

• additional layer forming by increasing RH to 60% and further growth of the water film up to 2.7 nm (ca. 10 monolayers) thickness at higher humidities [1]. On the atomic level, water and adsorbed molecules can arrange according to the surface structure and form ordered hydration layers that are also referred

• on the surface. This state is observed by the AFM technique as the surface topography. (2) In the second state the ions are dissolved in the hydration layer or in a physiosorbed or precursor state [30], which shows a high mobility and cannot be imaged. The material from the accumulation over time

Synthesis and potent cytotoxic activity of a novel diosgenin derivative and its phytosomes against lung cancer cells

• Liang Xu,
• Dekang Xu,
• Ziying Li,
• Yu Gao and
• Haijun Chen

Beilstein J. Nanotechnol. 2019, 10, 1933–1942, doi:10.3762/bjnano.10.189

• size distribution of phytosomes seems a little broad. We used the thin-film hydration method followed by sonication to prepare the phytosomes in this study. The mean size and size distribution are significantly influenced by the sonication conditions. Further optimization of the formulation and the

• . Preparation of phytosomes DiP and P2P were prepared with lecithin in the prescribed ratio (1:1, molar ratio) by the thin film hydration method. First, lecithin and Di/P2 were dissolved in chloroform at a molar ratio of 1:1. The organic solvent was evaporated using a rotary evaporator to produce a thin lipid

• film. Before hydration, the lipid film was dried in a vacuum drying chamber at 27 °C for 12 h. The hydrated multilamellar vesicles were sonicated by a sonicator for 20 min. Blank lipid nanoparticles (P) were also prepared with the same process without adding Di or P2. Characterization of phytosomes

Layered double hydroxide/sepiolite hybrid nanoarchitectures for the controlled release of herbicides

• Ediana Paula Rebitski,
• Margarita Darder and
• Pilar Aranda

Beilstein J. Nanotechnol. 2019, 10, 1679–1690, doi:10.3762/bjnano.10.163

• hydration or the presence of OH− species in the systems consolidated at lower temperature, which determines a different mechanism of attack of H+ to produce the degradation of the LDH and the subsequent release of entrapped MCPA. The fastest kinetics is observed with the lowest LDH content (Figure 7 and

Concurrent nanoscale surface etching and SnO₂ loading of carbon fibers for vanadium ion redox enhancement

• Jun Maruyama,
• Shohei Maruyama,
• Tomoko Fukuhara,
• Toru Nagaoka and
• Kei Hanafusa

Beilstein J. Nanotechnol. 2019, 10, 985–992, doi:10.3762/bjnano.10.99

• with the high-purity water to prepare a 2 M H2SO4 solution. Oxovanadium sulfate hydrate, VOSO4·nH2O, was purchased from Sigma-Aldrich (purity > 99.99%) and Nacalai Tesque, which was dissolved in 2 M H2SO4 to prepare VOSO4 (1 M)/H2SO4 (2 M). The number of water of hydration, n, was provided by the

Towards rare-earth-free white light-emitting diode devices based on the combination of dicyanomethylene and pyranine as organic dyes supported on zinc single-layered hydroxide

• Jeff L. Nyalosaso,
• Rachod Boonsin,
• Pierre Vialat,
• Damien Boyer,
• Geneviève Chadeyron,
• Rachid Mahiou and
• Fabrice Leroux

Beilstein J. Nanotechnol. 2019, 10, 760–770, doi:10.3762/bjnano.10.75

• temperature is related to M(RT) = 5·ZnO/(1 − 0.39) leading to 667.29 g·mol−1 (per 5·Zn) and corresponding to a hydration rate of n = 4.79, much higher than the value of 2 that is usually reported. It may be explained by a sample largely hydrated with weakly bonded water molecules as can be inferred from the

Outstanding chain-extension effect and high UV resistance of polybutylene succinate containing amino-acid-modified layered double hydroxides

• Adam A. Marek,
• Vincent Verney,
• Christine Taviot-Gueho,
• Grazia Totaro,
• Laura Sisti,
• Annamaria Celli and
• Fabrice Leroux

Beilstein J. Nanotechnol. 2019, 10, 684–695, doi:10.3762/bjnano.10.68

• equal because of the difference in molecular weight of the guest organic species as well as the different hydration rate. The UV-absorbing properties of the LDH structure with amino acids are presented in Figure 5. The nitrate–inorganic derivative, which is used as a reference, presents a typical quite

Ultrasonication-assisted synthesis of CsPbBr₃ and Cs₄PbBr₆ perovskite nanocrystals and their reversible transformation

• Longshi Rao,
• Xinrui Ding,
• Xuewei Du,
• Guanwei Liang,
• Yong Tang,
• Kairui Tang and
• Jin Z. Zhang

Beilstein J. Nanotechnol. 2019, 10, 666–676, doi:10.3762/bjnano.10.66

• by [PbX6]4− octahedra in which the Cs+ ions reside in the periphery of this network [9][10]. These PNCs are prone to structural instabilities and phase transformations involving ion migration and interface hydration [11]. However, this phase and structure versatility has become the great advantage of

Biomimetic surface structures in steel fabricated with femtosecond laser pulses: influence of laser rescanning on morphology and wettability

• Camilo Florian Baron,
• Alexandros Mimidis,
• Daniel Puerto,
• Evangelos Skoulas,
• Emmanuel Stratakis,
• Javier Solis and
• Jan Siegel

Beilstein J. Nanotechnol. 2018, 9, 2802–2812, doi:10.3762/bjnano.9.262

• related to water transport, although in this case not for camouflage but hydration purposes, which is vital considering the natural habitat of this lizard is the desert. The humidity in the air or moisture at the surface of rocks on which the lizard is standing can condense at the skin tiles, flowing

Comparative biological effects of spherical noble metal nanoparticles (Rh, Pd, Ag, Pt, Au) with 4–8 nm diameter

• Alexander Rostek,
• Marina Breisch,
• Kevin Pappert,
• Kateryna Loza,
• Marc Heggen,
• Manfred Köller,
• Christina Sengstock and
• Matthias Epple

Beilstein J. Nanotechnol. 2018, 9, 2763–2774, doi:10.3762/bjnano.9.258

• of agglomeration – a prerequisite for meaningful cell culture studies [47][86]. Note that the hydrodynamic diameter determined by DCS is systematically underestimated because of the hydration shell [87]. The average diameter of all particles was in the range between 5 and 10 nm. These results agree

Enhanced antineoplastic/therapeutic efficacy using 5-fluorouracil-loaded calcium phosphate nanoparticles

• Shanid Mohiyuddin,
• Saba Naqvi and
• Gopinath Packirisamy

Beilstein J. Nanotechnol. 2018, 9, 2499–2515, doi:10.3762/bjnano.9.233

• shown in the Figure 3C. The spherical structure can be readily observed in the negatively stained grids. The mean diameter as obtained from TEM micrographs is smaller than the hydrodynamic diameter concluded from the DLS analysis (Figure 2A) due to the lack of hydration layer [35] (dry sample) in TEM

Nanoconjugates of a calixresorcinarene derivative with methoxy poly(ethylene glycol) fragments for drug encapsulation

• Alina M. Ermakova,
• Julia E. Morozova,
• Yana V. Shalaeva,
• Victor V. Syakaev,
• Aidar T. Gubaidullin,
• Alexandra D. Voloshina,
• Vladimir V. Zobov,
• Irek R. Nizameev,
• Olga B. Bazanova,
• Igor S. Antipin and
• Alexander I. Konovalov

Beilstein J. Nanotechnol. 2018, 9, 2057–2070, doi:10.3762/bjnano.9.195

• macrocycle, the hydrophobic effect with its alkyl substituents and hydrogen, and donor–acceptor bonds with its polyethyleneoxy groups. The encapsulation was performed through thin-film hydration (also called evaporation method) or through solubilisation. Thin-film hydration means that ethanol solutions of

• of 3 (370 nm) compared to the mPEG-550 solution (362 nm) means a more hydrophobic microenvironment of the substrate in the macrocycle micelles [35]. The encapsulation of these substrates through thin-film hydration showed that the encapsulation efficiency (EE) of more hydrophobic Orange OT is a

• carried out by using thin-film hydration. The particle size distribution of 3 significantly changes in the presence of Dox: The averaged size of small particles increases from 8 to 16 nm and large particles disappear, which leads to a decrease of the PDI value (Figure S11a, Table S1, Supporting

Quantitative comparison of wideband low-latency phase-locked loop circuit designs for high-speed frequency modulation atomic force microscopy

• Kazuki Miyata and
• Takeshi Fukuma

Beilstein J. Nanotechnol. 2018, 9, 1844–1855, doi:10.3762/bjnano.9.176

• subnanometer-scale imaging of biomolecules [15][16][17]. Moreover, three-dimensional (3D) imaging techniques have been developed based on FM-AFM and used to visualize 3D distributions of hydration structures as well as flexible surface structures at solid–liquid interfaces [18][19][20][21][22]. Although FM-AFM

A simple extension of the commonly used fitting equation for oscillatory structural forces in case of silica nanoparticle suspensions

• Sebastian Schön and
• Regine von Klitzing

Beilstein J. Nanotechnol. 2018, 9, 1095–1107, doi:10.3762/bjnano.9.101

• additional term of repulsive nature that only affects small separations. Inspired by the additional terms shown by Israelachvili [51] for hydration forces near to a hydrophilic surface, a simple decaying exponential function was chosen leading to the new extended Equation 2: A fit of the data with this

Biological and biomimetic materials and surfaces

• Stanislav Gorb and
• Thomas Speck

Beilstein J. Nanotechnol. 2017, 8, 403–407, doi:10.3762/bjnano.8.42

• dispersal. Kreitschitz et al. studied these tribological properties of the seed envelope under different hydration conditions and revealed the presence of cellulose fibrils in the mucilage in a microscopy study, which are presumably responsible for the uniform distribution of the mucilaginous layer on the

“Sticky invasion” – the physical properties of Plantago lanceolata L. seed mucilage

• Agnieszka Kreitschitz,
• Alexander Kovalev and
• Stanislav N. Gorb

Beilstein J. Nanotechnol. 2016, 7, 1918–1927, doi:10.3762/bjnano.7.183

• envelope that also influence the dispersal of seeds. To determine the physical properties of Plantago lanceolata seed mucilage we studied (1) composition, (2) desiccation, (3) adhesion, and (4) friction properties of the mucilage under different hydration conditions. We revealed the presence of cellulose

• mucilage against loss from the seed surface. Keywords: adhesion; cellulose mucilage; desiccation; friction; Plantago lanceolata; Introduction The ability of seeds and fruits (diaspores) to form mucilage after hydration is known as myxospermy [1][2]. The mucilaginous diaspores are particularly

• wall that is rich in pectins form elastic, gel-like mucilage envelope after hydration [14][17]. Other components of the mucilage envelope such as cellulose fibrils also influence its properties and consequently its function. Seed mucilage possesses a clearly defined nanostructure. Cellulose is a linear

Influence of hydrothermal synthesis parameters on the properties of hydroxyapatite nanoparticles

• Sylwia Kuśnieruk,
• Jacek Wojnarowicz,
• Agnieszka Chodara,
• Tadeusz Chudoba,
• Stanislaw Gierlotka and
• Witold Lojkowski

Beilstein J. Nanotechnol. 2016, 7, 1586–1601, doi:10.3762/bjnano.7.153

• –600 °C [62]. Even if this simplification is imprecise, it is sufficient to indicate trends in apatite hydration. Therefore, the total water content in our samples decreases in the following order: Type 1 HAp > Type 2 HAp > Type 3 HAp > Type 4 HAp > Type 5 HAp > Type 6 HAp (Figure 12

Influence of ambient humidity on the attachment ability of ladybird beetles (Coccinella septempunctata)

• Lars Heepe,
• Jonas O. Wolff and
• Stanislav N. Gorb

Beilstein J. Nanotechnol. 2016, 7, 1322–1329, doi:10.3762/bjnano.7.123

• high amounts of water [47]. Peisker et al. [46] showed a 6000-fold increase in the Young’s modulus of the setal tips after drying. Consequently, the degree of hydration should also significantly affect the mechanical properties of the setae of the beetles in the present study and may also explain our

On the pathway of cellular uptake: new insight into the interaction between the cell membrane and very small nanoparticles

• Claudia Messerschmidt,
• Daniel Hofmann,
• Anja Kroeger,
• Katharina Landfester,
• Volker Mailänder and
• Ingo Lieberwirth

Beilstein J. Nanotechnol. 2016, 7, 1296–1311, doi:10.3762/bjnano.7.121

• determined. However, systematic errors of TEM micrograph processing together with a broad size distribution may be causal for this discrepancy. Since DLS measurements of nanoparticle size distribuitons are carried out in solution, the hydration shell of the nanoparticles additionally contributes to the

• particle radius value. On the other hand, TEM measurements require dried samples and hence no additional hydration shell contributes. Accordingly, DLS will systematically yield a slightly larger average particle size than the TEM measurement. Furthermore, DLS measurement integrates, as every scattering

Functional diversity of resilin in Arthropoda

• Jan Michels,
• Esther Appel and
• Stanislav N. Gorb

Beilstein J. Nanotechnol. 2016, 7, 1241–1259, doi:10.3762/bjnano.7.115

• and trityrosine, which were identified to form the cross-links between the polypeptide chains [9]. The mechanical properties of resilin strongly depend on the degree of hydration because resilin is plasticised by water [5]. When resilin is completely hydrated, it behaves close to a perfect rubber [3

• the relationship between the material properties and the hydration status of resilin mentioned above. Besides the differences in the Young’s modulus, the mechanical behaviour of the respective materials shows the pronounced differences in the material composition between the tips and the bases of

• contribution of the large resilin proportions in the setal tips to the attachment performance of the adhesive pads on a high level, the hydration of the resilin must be maintained. It is imaginable that this is achieved by slowly evaporating tarsal liquids covering the setae and thereby keeping the resilin in

Hydration of magnesia cubes: a helium ion microscopy study

• Ruth Schwaiger,
• Johannes Schneider,
• Gilles R. Bourret and
• Oliver Diwald

Beilstein J. Nanotechnol. 2016, 7, 302–309, doi:10.3762/bjnano.7.28

• H2O depending on their size and distribution at the sample surface. Comparison between (a) and (b) points to the volume expansion during hydration and hydroxylation, while (c) and (d) show a probable dissolution/precipitation mechanism. (HIM SE images recorded at 30 kV acceleration voltage and (a,c

3D solid supported inter-polyelectrolyte complexes obtained by the alternate deposition of poly(diallyldimethylammonium chloride) and poly(sodium 4-styrenesulfonate)

• Eduardo Guzmán,
• Armando Maestro,
• Sara Llamas,
• Jesús Álvarez-Rodríguez,
• Francisco Ortega,
• Ángel Maroto-Valiente and
• Ramón G. Rubio

Beilstein J. Nanotechnol. 2016, 7, 197–208, doi:10.3762/bjnano.7.18

• -dimensional solid-supported inter-polyelectrolyte films. The growth mechanism of the multilayers, followed using a quartz crystal microbalance, evidences two different growth trends, which show a dependency on the ionic strength due to its influence onto the polymer conformation. The hydration state does not

• the polyelectrolyte multilayers. Keywords: charge compensation; hydration; polyelectrolyte multilayers; stratification; swelling; Introduction The new requirements of science and technology have created an increasing interest for the fabrication of materials with reduced dimensionality for their

• interactions occurring in the system and the polymer conformation, without effects due to the hydration/swelling phenomena associated with the uptake/release of water. Even though the N dependence of the adsorbed mass is not changed by the drying process, other aspects are strongly modified by the film drying

Capillary and van der Waals interactions on CaF₂ crystals from amplitude modulation AFM force reconstruction profiles under ambient conditions

• Annalisa Calò,
• Oriol Vidal Robles,
• Sergio Santos and
• Albert Verdaguer

Beilstein J. Nanotechnol. 2015, 6, 809–819, doi:10.3762/bjnano.6.84

• ]. This is particularly true when working in air under ambient conditions, where the presence of thin layers of water is ubiquitous even on highly hydrophobic surfaces [8][9][10] and specific interactions (hydration, capillary forces) [11] need to be accounted for, which can be effective at relatively

Overview about the localization of nanoparticles in tissue and cellular context by different imaging techniques

• Anja Ostrowski,
• Daniel Nordmeyer,
• Alexander Boreham,
• Cornelia Holzhausen,
• Lars Mundhenk,
• Christina Graf,
• Martina C. Meinke,
• Annika Vogt,
• Sabrina Hadam,
• Jürgen Lademann,
• Eckart Rühl,
• Ulrike Alexiev and
• Achim D. Gruber

Beilstein J. Nanotechnol. 2015, 6, 263–280, doi:10.3762/bjnano.6.25

• , dehydration effects may deleteriously affect the ultrastructure of tissues [162]. Therefore, cryogenic approaches in which chemical fixation is avoided and the normal hydration state is maintained may be advantageous for a more life-like preservation of biological samples [163]. Cryo-TEM has been used to

Materials and characterization techniques for high-temperature polymer electrolyte membrane fuel cells

• Roswitha Zeis

Beilstein J. Nanotechnol. 2015, 6, 68–83, doi:10.3762/bjnano.6.8

• exhibit high proton conductivity in low-hydration and even anhydrous states. Of special concern for phosphoric-acid-doped PBI-type membranes is the acid loss and management during operation. The slow oxygen reduction reaction in HT-PEMFCs remains a challenge. Phosphoric acid tends to adsorb onto the

• further increase in current density to 300 mA/cm2 and 500 mA/cm2 did not lead to a significant additional swelling of the membrane. After returning to zero current, the membrane thickness was restored to the original value before the load cycle. The swelling of the membrane can be explained by hydration