Quality by design optimization of microemulsions for topical delivery of Passiflora setacea seed oil

• Daniel T. Pereira,
• Douglas Dourado,
• Danielle T. Freire,
• Dayanne L. Porto,
• Cícero F. S. Aragão,
• Myla L. de Souza,
• Guilherme R. S. de Araujo,
• Ana Maria Costa,
• Wógenes N. Oliveira,
• Anne Sapin-Minet,
• Éverton N. Alencar and
• Eryvaldo Sócrates T. Egito

Beilstein J. Nanotechnol. 2025, 16, 2116–2131, doi:10.3762/bjnano.16.146

• . Subsequently, Liquid Germall® Plus (0.2% w/w) and sodium carboxymethylcellulose (1.5% w/w) were added under mechanical stirring to obtain the gelled topical microemulsion. Characterization of the emulsified systems Hydrodynamic diameter distribution The hydrodynamic diameter and polydispersity index of the

Rapid synthesis of highly monodisperse AgSbS₂ nanocrystals: unveiling multifaceted activities in cancer therapy, antibacterial strategies, and antioxidant defense

• Funda Ulusu,
• Adem Sarilmaz,
• Yakup Ulusu,
• Faruk Ozel and
• Mahmut Kus

Beilstein J. Nanotechnol. 2025, 16, 2105–2115, doi:10.3762/bjnano.16.145

• , Department of Mechanical Engineering, 53020, Rize, Turkey Department of Chemical Engineering, Konya Technical University, Konya, Turkey 10.3762/bjnano.16.145 Abstract Nanocrystals (NCs) of silver antimony sulfide (AgSbS2) in the cubic phase were successfully synthesized using the hot-injection method. This

Multifrequency AFM integrating PeakForce tapping and higher eigenmodes for heterogeneous surface characterization

• Yanping Wei,
• Jiafeng Shen,
• Yirong Yao,
• Xuke Li,
• Ming Li and
• Peiling Ke

Beilstein J. Nanotechnol. 2025, 16, 2077–2085, doi:10.3762/bjnano.16.142

• environments such as liquids [18][19]. As demonstrated by force–distance curve analyses [19], PFT enables direct extraction of quantitative mechanical properties (e.g., Young’s modulus and adhesion) for material discrimination. However, this capability is constrained by the requirement for precise probe

• overcome these challenges. This configuration harnesses the mechanical precision of quasi-static force control and the sensitivity of eigenmode signals to variations in surface properties and enables simultaneous topographical, mechanical, and compositional mapping. We apply this technique to

• withdraw with the sample surface periodically, forming a force curve. The peak force, identified within this curve, is utilized as a feedback parameter. By sustaining a constant peak force between the probe and the sample, the topography of the sample can be obtained. Quantitative mechanical properties of

Molecular and mechanical insights into gecko seta adhesion: multiscale simulations combining molecular dynamics and the finite element method

• Yash Jain,
• Saeed Norouzi,
• Tobias Materzok,
• Stanislav N. Gorb and
• Florian Müller-Plathe

Beilstein J. Nanotechnol. 2025, 16, 2055–2076, doi:10.3762/bjnano.16.141

• dynamics to capture molecular interactions at the spatula–substrate interface and finite element method to simulate the mechanical behavior of the larger setal shaft. This hybrid approach enables synchronized simulations that resolve both fine-scale interfacial dynamics and overall structural deformation

• continuum and particle domains exchange information through a handshake region using our coupling algorithm, which will be detailed in Section “Methods”. The simulations presented in this paper visualize the mechanical response of whole seta and the peeling of spatulae during pull-off from a dry, smooth

• structure similar to a fiber-reinforced elastomer, with a fibrillar nature that leads to anisotropic mechanical properties [40][41][42]. Rather than explicitly resolving individual fibers and the surrounding amorphous matrix, we represented the spatula with a coarse-grained bead network whose anisotropic

Beyond the shell: exploring polymer–lipid interfaces in core–shell nanofibers to carry hyaluronic acid and β-caryophyllene

• Aline Tavares da Silva Barreto,
• Francisco Alexandrino-Júnior,
• Bráulio Soares Arcanjo,
• Paulo Henrique de Souza Picciani and
• Kattya Gyselle de Holanda e Silva

Beilstein J. Nanotechnol. 2025, 16, 2015–2033, doi:10.3762/bjnano.16.139

• advancements in the controlled release of diverse bioactive compounds [5][6][7][8][9][10]. Among the various nanostructured platforms explored for these purposes, nanofibers have gained attention due to their high surface area, adjustable porosity, and robust mechanical properties, which set them apart from

• concentration, surface tension, conductivity, and solvent volatility, alongside careful consideration of electrospinning conditions, such as temperature and humidity [18][19]. The polymer selection of nanofibers intended for biomedical applications must prioritize not only mechanical strength, controlled

• mechanical strength, assist in managing wound exudates, and maintain a moist wound bed. Its properties can also be tailored through blends with different forms of PLA or other biopolymers to achieve desired tensile strength, release profiles, or biodegradation characteristics [24][25]. The growing commercial

The cement of the tube-dwelling polychaete Sabellaria alveolata: a complex composite adhesive material

• Emilie Duthoo,
• Aurélie Lambert,
• Pierre Becker,
• Carla Pugliese,
• Jean-Marc Baele,
• Arnaud Delfairière,
• Matthew J. Harrington and
• Patrick Flammang

Beilstein J. Nanotechnol. 2025, 16, 1998–2014, doi:10.3762/bjnano.16.138

• cement spots treated with EDTA compared to untreated spots [39]. Moreover, EDTA treatment had a strong effect on the mechanical properties of the cement [39]. Proteins involved in the adhesive system In S. alveolata, the localization of the adhesive proteins Sa-1 and Sa-3 in cement cells with

Mechanical property measurements enabled by short-term Fourier-transform of atomic force microscopy thermal deflection analysis

• Thomas Mathias,
• Roland Bennewitz and
• Philip Egberts

Beilstein J. Nanotechnol. 2025, 16, 1952–1962, doi:10.3762/bjnano.16.136

• Thomas Mathias Roland Bennewitz Philip Egberts Department of Mechanical and Manufacturing Engineering, University of Calgary, 2500 University Drive NW, Calgary, AB, T2N 1Y6, Canada INM-Leibniz Institute for New Materials, Campus D2 2, 66123 Saarbrücken, Germany 10.3762/bjnano.16.136 Abstract

• ); mechanical property measurements; surface science; Introduction Atomic force microscopy (AFM) has become an indispensable tool for imaging the surface topography on a variety of surfaces [1]. Since the invention of the AFM [2], several other modes of AFM have been developed, including friction force

• bring physical values or interpretation to the data that is collected by the AFM, allowing operators of the technique to compare their measurements across fields [6]. CR-AFM is a technique that was established in 2008, allowing for the measurement of mechanical properties (elastic modulus and

Evaluating metal-organic precursors for focused ion beam-induced deposition through solid-layer decomposition analysis

• Benedykt R. Jany,
• Katarzyna Madajska,
• Aleksandra Butrymowicz-Kubiak,
• Franciszek Krok and
• Iwona B. Szymańska

Beilstein J. Nanotechnol. 2025, 16, 1942–1951, doi:10.3762/bjnano.16.135

• deposition, chemical mechanical polishing, and laser nanopatterning, enable the creation of nanostructures and nanoscale devices. However, a major limitation of these methods is their inability to effectively produce high-resolution three-dimensional nanostructures [1][2][3][4]. In contrast, focused electron

Targeting the vector of arboviruses Aedes aegypti with nanoemulsions based on essential oils: a review with focus on larvicidal and repellent properties

• Laryssa Ferreira do Nascimento Silva,
• Douglas Dourado,
• Thayse Silva Medeiros,
• Mariana Alice Gonzaga Gabú,
• Maria Cecilia Queiroga dos Santos,
• Daiane Rodrigues dos Santos,
• Mylena Lemos dos Santos,
• Gabriel Bezerra Faierstein,
• Rosângela Maria Rodrigues Barbosa and
• Fabio Rocha Formiga

Beilstein J. Nanotechnol. 2025, 16, 1894–1913, doi:10.3762/bjnano.16.132

• Bacillus thuringiensis israelensis (Bti); mechanical control, based on improving basic sanitation and infrastructure to eliminate breeding sites; and behavioral control, which promotes the adoption of practices such as the use of traps to capture mosquitoes at different life stages [9][10][11][12]. In this

• trichomes, which are the secretory tissues present in different vegetative parts of plants, such as leaves, flowers, roots, fruits, or stems [67]. These can be obtained by distillation with water or steam, microwave or ultrasound assisted extraction, or from the epicarp of fruits by a mechanical process, or

Low-temperature AFM with a microwave cavity optomechanical transducer

• Ermes Scarano,
• Elisabet K. Arvidsson,
• August K. Roos,
• Erik Holmgren,
• Riccardo Borgani,
• Mats O. Tholén and
• David B. Haviland

Beilstein J. Nanotechnol. 2025, 16, 1873–1882, doi:10.3762/bjnano.16.130

• causing significant wideband mechanical vibrations, which can propagate through the cold stages down to the measurement apparatus. However, force sensors with integrated position detectors, as the one presented in this work, do not require free-space optical alignment with a long optical path length. They

• features in a 1 µm scan field, but has not been tested to atomic resolution. Results and Discussion Force sensitivity and imaging The microcantilever in dynamic AFM operates as a resonant force transducer. Each individual eigenmode is described by a mechanical susceptibility χ, expressing cantilever

• -independent added noise of the detection SVV [V2/Hz], which is converted to an equivalent deflection noise via the detector responsivity α [V/m]: Neglecting back action, the noise-equivalent force for a given measurement bandwidth Δf is given by This quantity is minimized at the mechanical resonance

Self-assembly and adhesive properties of Pollicipes pollicipes barnacle cement protein cp19k: influence of pH and ionic strength

• Shrutika Sawant,
• Anne Marie Power and
• J. Gerard Wall

Beilstein J. Nanotechnol. 2025, 16, 1863–1872, doi:10.3762/bjnano.16.129

• bond formation, metal chelation, and covalent interactions [6]. The byssal threads display a mechanical gradient, with regions proximal to the animal more elastic and distal regions stiffer and tougher [7]. This design allows for effective dissipation of hydrodynamic forces and maintains attachment of

• (basic pH with high salt concentration) or proposed gland-like (acidic pH with low salt concentration) conditions [28][29][30][31], however, with much still unknown about their structural properties or mechanical function under varied environmental conditions. Among P. pollicipes cement proteins, cp19k

On the road to sustainability – application of metallic nanoparticles obtained by green synthesis in dentistry: a scoping review

• Lorena Pinheiro Vasconcelos Silva,
• Joice Catiane Soares Martins,
• Israel Luís Carvalho Diniz,
• Júlio Abreu Miranda,
• Danilo Rodrigues de Souza,
• Éverton do Nascimento Alencar,
• Moan Jéfter Fernandes Costa and
• Pedro Henrique Sette-de-Souza

Beilstein J. Nanotechnol. 2025, 16, 1851–1862, doi:10.3762/bjnano.16.128

• containing biogenic AgNPs are being investigated as adjunctive therapies to improve oral hygiene in patients with fixed orthodontic appliances [8][37][44]. These strategies aim to balance microbial control while preserving the mechanical performance of orthodontic devices. Green-synthesized nanoparticles

Further insights into the thermodynamics of linear carbon chains for temperatures ranging from 13 to 300 K

• Alexandre Rocha Paschoal,
• Thiago Alves de Moura,
• Juan S. Rodríguez-Hernández,
• Carlos William de Araujo Paschoal,
• Yoong Ahm Kim,
• Morinobu Endo and
• Paulo T. Araujo

Beilstein J. Nanotechnol. 2025, 16, 1818–1825, doi:10.3762/bjnano.16.125

• gradients), and mechanical (e.g., pressure variations) stimuli [1][2][3][4][5][6][7][8][9][10][11][12][13][14][15][16][17][18][19][20][21][22][23]. These responses are directly connected with electronic and transport properties, which in turn depend on the equilibrium between emission and absorption of

• materials as well as the understanding of how such phonons relate to thermal and mechanical properties of the materials become of fundamental importance [1][2][3][4][5][6][7][8][9][10][11][12][13][14][15][16][17][18][19][20][21][22][23][24][25][26][27][28][29][30]. One important point to keep in mind is

• allows thermal and mechanical properties of materials to be described by semi-classical theories (such as the Debye’s theory that describes the behavior of materials with T), and their phonon frequencies might be directly connected with relevant parameters such as the Young’s modulus, the Grüneisen

Piezoelectricity of layered double hydroxides: perspectives regarding piezocatalysis and nanogenerators

• Evgeniy S. Seliverstov,
• Evgeniya A. Tarasenko and
• Olga E. Lebedeva

Beilstein J. Nanotechnol. 2025, 16, 1812–1817, doi:10.3762/bjnano.16.124

• environmental sources is a priority. Piezoelectric materials have the ability to convert mechanical energy into electrical energy due to the arrangement of dipoles in their structure, thus providing sustainable electrical energy for low-power-consuming and self-powered devices [1]. The most common piezoelectric

• current output. The piezoelectric potential generated in the ZnO nanosheets functions as an applied voltage, facilitating charge storage within the LDH layers, which act as capacitors. This mechanism leads to enhanced voltage and current pulses under mechanical stimulation. LDHs can also enhance the

• emerging area of catalysis utilizes the ability of piezoelectric materials to convert mechanical energy into electrical energy for subsequent electrochemical reactions [13]. Liu et al. suggested that ultrathin Ni/Fe-LDH modified with polyethylene glycol (PEG) for better water solubility and

Electrical, photocatalytic, and sensory properties of graphene oxide and polyimide implanted with low- and medium-energy silver ions

• Josef Novák,
• Eva Štěpanovská,
• Petr Malinský,
• Vlastimil Mazánek,
• Jan Luxa,
• Ulrich Kentsch and
• Zdeněk Sofer

Beilstein J. Nanotechnol. 2025, 16, 1794–1811, doi:10.3762/bjnano.16.123

• analysis. The surface morphology and roughness of the non-implanted and implanted samples were measured using AFM (Dimension ICON, Bruker) in quantitative nanoscale mechanical (QNM) mode under ambient conditions. A SCANASYST-AIR tip made of nitride with an elastic constant of 0.4 N·m−1 was utilized for the

Exploring the potential of polymers: advancements in oral nanocarrier technology

• Rousilândia de Araujo Silva,
• Igor Eduardo Silva Arruda,
• Luise Lopes Chaves,
• Mônica Felts de La Roca Soares and
• Jose Lamartine Soares Sobrinho

Beilstein J. Nanotechnol. 2025, 16, 1751–1793, doi:10.3762/bjnano.16.122

• unique spatial attributes, with monomeric structures and functional groups, hydrophobic or hydrophilic, that determine its properties [60]. The nature of monomers correlates with polymer crystallinity, which, in turn, defines mechanical strength, swelling, hydrolysis, and biodegradation rates

• transfer throughout the entire polymer matrix. However, in NPs, a balance between amorphous and crystalline states is necessary to optimize mechanical strength and drug release rates. The glass transition temperature reflects the polymer chain’s permeability and mobility, influencing its susceptibility to

Beyond the bilayer: multilayered hygroscopic actuation in pine cone scales

• Kim Ulrich,
• Max David Mylo,
• Tom Masselter,
• Fabian Scheckenbach,
• Sophia Fischerbauer,
• Martin Nopens,
• Silja Flenner,
• Imke Greving,
• Linnea Hesse and
• Thomas Speck

Beilstein J. Nanotechnol. 2025, 16, 1695–1710, doi:10.3762/bjnano.16.119

• properties and tissue arrangements for predicting pine cone scale bending in silico. By contributing to a deeper understanding of pine cone scale biomechanics, these results also support the development of bioinspired technical applications. Future studies should refine tissue mechanical properties and

• in the following. To analyze the influence of the mechanical properties, in another simulation of the bilayer, the value of the Young's modulus of the sclerenchyma fibers was adjusted to that of the brown tissue (from 500 to 50 MPa). To analyze the influence of the Young's modulus of the brown tissue

• opening angle than those from the basal part. This may be attributed to variations in tissue composition or mechanical and hygroscopic properties along the cone. In the case of basal scales, our measured opening angle is underestimated due to the chosen method of angle calculation and the strong curvature

Nanotechnology-based approaches for the removal of microplastics from wastewater: a comprehensive review

• Nayanathara O Sanjeev,
• Manjunath Singanodi Vallabha and
• Rebekah Rubidha Lisha Rabi

Beilstein J. Nanotechnol. 2025, 16, 1607–1632, doi:10.3762/bjnano.16.114

• associated modules. The efficiency of a membrane system is primarily governed by the material used in its construction. Enhancing membranes with functional nanomaterials provides a promising path to boost permeability, reduce fouling, and increase both mechanical and thermal durability, while also enabling

• from aquatic systems. MXenes have emerged as promising materials for antibacterial applications and have shown strong potential for the use in water purification membranes due to their excellent film-forming ability and enhanced mechanical strength. These properties also support their application in

• nanomaterials present several benefits for removing MPs from water. Their exceptionally large surface area and distinct structural features contribute to effective microplastic capture. Materials like CNTs also offer excellent mechanical strength and can be engineered for durability under extreme conditions

Bioinspired polypropylene-based functionally graded materials and metamaterials modeling the mistletoe–host interface

• Lina M. Rojas González,
• Naeim Ghavidelnia,
• Christoph Eberl and
• Max D. Mylo

Beilstein J. Nanotechnol. 2025, 16, 1592–1606, doi:10.3762/bjnano.16.113

• striking example is the hemiparasitic European mistletoe (Viscum album), which forms a lifelong (over 20 years) connection with its host tree, providing physiological supply and mechanical anchorage. The V-shaped interface between mistletoe and host is characterized by a lignification and cell wall

• gradient that bridges the mechanical differences between the adjacent tissues. These characteristics of the mistletoe–host interface can be transferred to functionally graded polymeric materials. Using extrusion molding and hot pressing, we developed a material system that combines pure and glass-fiber

• failure locations can be introduced, which should have little or no effect on the overall mechanical properties in the regular product environment. A class of materials characterized by a high degree of flexibility and distribution of material properties, which enables locally adapted behavior and, thus

Transient electronics for sustainability: Emerging technologies and future directions

• Jae-Young Bae,
• Myung-Kyun Choi and
• Seung-Kyun Kang

Beilstein J. Nanotechnol. 2025, 16, 1545–1556, doi:10.3762/bjnano.16.109

• transient systems must be optimized to balance electrical performance, biodegradation kinetics, and mechanical integrity. Moreover, to transcend basic sensing and stimulation functions, and to enable capabilities such as computation, memory, and autonomous decision-making, the development of high

• bioresorption in vivo [14]. Zinc has been proposed for use in bioabsorbable vascular stents, demonstrating ideal degradation behavior and mechanical integrity in animal models [51]. AZ31B, along with molybdenum and tungsten, have been investigated as a substrate and conductive layer in transient electronics due

• but also of electrical and mechanical performance. For instance, Mg-3Zn, which suffers from phase separation in bulk form, can be synthesized as a uniform alloy in thin films, offering improved corrosion resistance [61]. Moreover, bioresorbable amorphous metal (metallic glass) films have demonstrated

Influence of laser beam profile on morphology and optical properties of silicon nanoparticles formed by laser ablation in liquid

• Natalie Tarasenka,
• Vladislav Kornev,
• Alena Nevar and
• Nikolai Tarasenko

Beilstein J. Nanotechnol. 2025, 16, 1533–1544, doi:10.3762/bjnano.16.108

• number of benefits from the mechanical and chemical stability of the carbon cloth material, which, together with its low cost and large surface area, make it especially promising for the flexible devices. The results of these experiments are the subject of upcoming works. Conclusion In summary, laser

Dendrimer-modified carbon nanotubes for the removal and recovery of heavy metal ions from water

• Thao Quynh Ngan Tran,
• Huu Trung Nguyen,
• Subodh Kumar and
• Xuan Thang Cao

Beilstein J. Nanotechnol. 2025, 16, 1522–1532, doi:10.3762/bjnano.16.107

• dendrimers on a solid support can also improve the dispersibility, accessibility of binding sites, chemical recyclability, and mechanical stability [16][17]. In fact, dendrimers have been supported by various nanomaterials such as silica, graphene oxide, and carbon nanotubes (CNTs), broadening their

• application in numerous fields [18][19][20][21][22][23]. CNTs are particularly attractive as support materials due to their high specific surface area, mechanical strength, and excellent electrical and thermal conductivity [24][25][26][27]. CNTs themselves have been utilized as adsorbents for removing heavy

Laser processing in liquids: insights into nanocolloid generation and thin film integration for energy, photonic, and sensing applications

• Akshana Parameswaran Sreekala,
• Pooja Raveendran Nair,
• Jithin Kundalam Kadavath,
• Bindu Krishnan,
• David Avellaneda Avellaneda,
• M. R. Anantharaman and
• Sadasivan Shaji

Beilstein J. Nanotechnol. 2025, 16, 1428–1498, doi:10.3762/bjnano.16.104

• obtained. These mechanisms play a crucial role in determining the characteristics of the final products, whether they be spherical NPs, QDs, or other nanostructures, depending on the specific goals of the synthesis. NPs exhibit distinct mechanical and physicochemical properties that are influenced by

Parylene-coated platinum nanowire electrodes for biomolecular sensing applications

• Chao Liu,
• Peker Milas,
• Michael G. Spencer and
• Birol Ozturk

Beilstein J. Nanotechnol. 2025, 16, 1392–1400, doi:10.3762/bjnano.16.101

• -C monomer, where an Edwards E2M1.5 mechanical vacuum pump was used to maintain the vacuum in the 0.133 to 1.33 Pa range during the process. A CPS VG200 vacuum gauge was used for monitoring the pressure. Usually, 4–6 DENA-grown platinum nanowires on the tips of tungsten rods were placed 45° (from

Ferroptosis induction by engineered liposomes for enhanced tumor therapy

• Alireza Ghasempour,
• Mohammad Amin Tokallou,
• Mohammad Reza Naderi Allaf,
• Mohsen Moradi,
• Hamideh Dehghan,
• Mahsa Sedighi,
• Mohammad-Ali Shahbazi and
• Fahimeh Lavi Arab

Beilstein J. Nanotechnol. 2025, 16, 1325–1349, doi:10.3762/bjnano.16.97