Biomimetic nanocarriers: integrating natural functions for advanced therapeutic applications

• Hugo Felix Perini,
• Beatriz Sodré Matos,
• Carlo José Freire de Oliveira and
• Marcos Vinicius da Silva

Beilstein J. Nanotechnol. 2024, 15, 1619–1626, doi:10.3762/bjnano.15.127

• advancements nanocarriers have brought to medical sciences, particularly in cancer treatment, several challenges remain for their widespread application. Issues such as cytotoxicity, difficulties in management, encapsulation, and in vivo release pose barriers to the application of nanocarriers [16][17]. In

Natural nanofibers embedded in the seed mucilage envelope: composite hydrogels with specific adhesive and frictional properties

• Agnieszka Kreitschitz and
• Stanislav N. Gorb

Beilstein J. Nanotechnol. 2024, 15, 1603–1618, doi:10.3762/bjnano.15.126

• encapsulation of medical substances. A very important advantage of diaspore mucilages are their antimicrobial properties [105][106][110][111]. Phenolic compounds are secondary plant metabolites, which demonstrate a wide range of structures, from simple molecules to polymeric compounds. They can be produced in

• production of biofilms, encapsulation, or lubricants with medical application [106][110][111][116][117]. Our findings may also help to design pathogen-resistant lubricating biomaterials with low friction, which can be achieved in rather simply way by adding phenolic substances to the medical hydrogels [98

• medical waste“, © Pöllö, published via Wikimedia Commons, distributed under the terms of the Creative Commons Attribution 3.0 Generic License, https://creativecommons.org/licenses/by/3.0/). Salvia hispanica dry seed. (a) The whole seed is covered with mucilaginous cells. (b) The mucilaginous cells (mc

Liver-targeting iron oxide nanoparticles and their complexes with plant extracts for biocompatibility

• Shushanik A. Kazaryan,
• Seda A. Oganian,
• Gayane S. Vardanyan,
• Anatolie S. Sidorenko and
• Ashkhen A. Hovhannisyan

Beilstein J. Nanotechnol. 2024, 15, 1593–1602, doi:10.3762/bjnano.15.125

• Shushanik A. Kazaryan Seda A. Oganian Gayane S. Vardanyan Anatolie S. Sidorenko Ashkhen A. Hovhannisyan Department of Medical Biochemistry and Biotechnology, Russian-Armenian (Slavonic) University, Hovsep Emin St 123, Yerevan, Armenia Yerevan State Medical University After M. Heraci, Department of

• , biochemistry, biophysics, and other disciplines within biology and medicine [1][2][3][4][5]. The development of nanotechnology has provided resources for various applications in the medical field, leading to significant advances in diagnosis, biological detection, therapy, and drug delivery [6][7][8][9]. An

• in most biological and chemical reactions involved in the production of medical materials [10][11][12][13]. Magnetic nanoparticles (MNPs), such as iron oxides, not only exhibit superparamagnetism and high magnetic susceptibility, they also possess unique physical properties, biocompatibility

Green synthesis of silver nanoparticles derived from algae and their larvicidal properties to control Aedes aegypti

• Matheus Alves Siqueira de Assunção,
• Douglas Dourado,
• Daiane Rodrigues dos Santos,
• Gabriel Bezerra Faierstein,
• Mara Elga Medeiros Braga,
• Severino Alves Junior,
• Rosângela Maria Rodrigues Barbosa,
• Herminio José Cipriano de Sousa and
• Fábio Rocha Formiga

Beilstein J. Nanotechnol. 2024, 15, 1566–1575, doi:10.3762/bjnano.15.123

• , PE, Brazil Faculty of Medical Sciences, University of Pernambuco (UPE), 52171-011, Recife, PE, Brazil 10.3762/bjnano.15.123 Abstract Mosquito vectors such as Aedes spp. are responsible for the transmission of arboviruses that have a major impact on public health. Therefore, it is necessary to search

Polymer lipid hybrid nanoparticles for phytochemical delivery: challenges, progress, and future prospects

• Iqra Rahat,
• Pooja Yadav,
• Aditi Singhal,
• Mohammad Fareed,
• Jaganathan Raja Purushothaman,
• Mohammed Aslam,
• Raju Balaji,
• Sonali Patil-Shinde and
• Md. Rizwanullah

Beilstein J. Nanotechnol. 2024, 15, 1473–1497, doi:10.3762/bjnano.15.118

• Iqra Rahat Pooja Yadav Aditi Singhal Mohammad Fareed Jaganathan Raja Purushothaman Mohammed Aslam Raju Balaji Sonali Patil-Shinde Md. Rizwanullah Department of Pharmaceutical Technology, Meerut Institute of Engineering and Technology, Meerut-250005, Uttar Pradesh, India Department of Basic Medical

• Sciences, College of Medicine, AlMaarefa University, P.O. Box 71666, Riyadh 11597, Saudi Arabia Department of Orthopaedics, Saveetha Medical College and Hospital, Saveetha Institute of Medical and Technical Sciences (SIMATS), Saveetha University, Chennai-602105, Tamil Nadu, India Pharmacy Department, Tishk

• International University, Erbil 44001, Kurdistan Region, Iraq Center for Global Health Research, Saveetha Medical College and Hospital, Saveetha Institute of Medical and Technical Sciences (SIMATS), Saveetha University, Chennai-602105, Tamil Nadu, India Department of Pharmaceutical Chemistry, Dr. D.Y Patil

Hymenoptera and biomimetic surfaces: insights and innovations

• Vinicius Marques Lopez,
• Carlo Polidori and
• Rhainer Guillermo Ferreira

Beilstein J. Nanotechnol. 2024, 15, 1333–1352, doi:10.3762/bjnano.15.107

• materials and devices that replicate the efficiency and functionality of insect body structures, driving progress in medical technology, robotics, environmental monitoring, and beyond. Keywords: arthropods; bio-inspired surfaces; bioengineering; cuticle; nanoscale structures; Introduction The body

• of particles [19]. Similarly, in the medical field, these coatings can be used on surgical instruments and prosthetics to minimize friction against biological tissues, reducing discomfort and improving the functionality of medical devices. Furthermore, in the field of electronics, low-friction

• [62][63]. Recently, the mandibles of leafcutter ants have inspired the design of a biomimetic stubble-cutting device, showcasing excellent performance and potential applications in agriculture [64]. Ant mandibles offer valuable inspiration for the enhancement of medical tools and devices. For instance

Dual-functionalized architecture enables stable and tumor cell-specific SiO₂NPs in complex biological fluids

• Iris Renata Sousa Ribeiro,
• Raquel Frenedoso da Silva,
• Romênia Ramos Domingues,
• Adriana Franco Paes Leme and
• Mateus Borba Cardoso

Beilstein J. Nanotechnol. 2024, 15, 1238–1252, doi:10.3762/bjnano.15.100

• exhibit heightened efficacy and reduced toxicity for medical purposes. Keywords: colloidal stability; complex media; functionalized nanoparticles; hemolysis; targeting tumor; Introduction In recent years, there has been a growing search for developing high-efficiency nanomedicines for cancer treatment

• of pivotal relevance for obtaining more reliable results and open possibilities for developing NPs that are increasingly efficient and suitable for medical applications. Ensuring that a platform efficiently functions for in vitro assays is a crucial step in predicting in vivo effects. Our system

A low-kiloelectronvolt focused ion beam strategy for processing low-thermal-conductance materials with nanoampere currents

• Annalena Wolff,
• Nico Klingner,
• William Thompson,
• Yinghong Zhou,
• Jinying Lin and
• Yin Xiao

Beilstein J. Nanotechnol. 2024, 15, 1197–1207, doi:10.3762/bjnano.15.97

• Xiamen Medical College, Fujian, China School of Medicine and Dentistry, Griffith University, Gold Coast QLD 4222, Australia 10.3762/bjnano.15.97 Abstract Ion beam-induced heat damage in thermally low conductive specimens such as biological samples is gaining increased interest within the scientific

Introducing third-generation periodic table descriptors for nano-qRASTR modeling of zebrafish toxicity of metal oxide nanoparticles

• Supratik Kar and
• Siyun Yang

Beilstein J. Nanotechnol. 2024, 15, 1142–1152, doi:10.3762/bjnano.15.93

• strong antibacterial, antifungal, antidiabetic, antioxidant, anticancer, and photocatalytic activities [7][8][9]. Besides the medical field, they are also commonly used in commercial products such as fuel cells and plastics, and environmental applications such as analysis, sensing, remediation, and

• findings of this study have significant implications for the use of MONPs in medical applications. Nanoparticles are increasingly explored regarding drug delivery, imaging, and therapeutic purposes. Understanding the toxicity mechanisms and predicting potential adverse effects of MONPs can guide the design

Recent updates in applications of nanomedicine for the treatment of hepatic fibrosis

• Damai Ria Setyawati,
• Fransiska Christydira Sekaringtyas,
• Riyona Desvy Pratiwi,
• A’liyatur Rosyidah,
• Rohimmahtunnissa Azhar,
• Nunik Gustini,
• Gita Syahputra,
• Idah Rosidah,
• Etik Mardliyati,
• Tarwadi and
• Sjaikhurrizal El Muttaqien

Beilstein J. Nanotechnol. 2024, 15, 1105–1116, doi:10.3762/bjnano.15.89

• fact that there are over 50 nanotechnology-based medical products approved by regulatory bodies worldwide for various medical purposes, including AmBisome® (liposomal amphotericin B) for fungal infections, Visudyn® (liposomal vertepor) for macular degeneration, and Onpattro® (lipid nanoparticles with

Unveiling the potential of alginate-based nanomaterials in sensing technology and smart delivery applications

• Shakhzodjon Uzokboev,
• Khojimukhammad Akhmadbekov,
• Ra’no Nuritdinova,
• Salah M. Tawfik and
• Yong-Ill Lee

Beilstein J. Nanotechnol. 2024, 15, 1077–1104, doi:10.3762/bjnano.15.88

• potential risks or complications [42]. Recently, researchers and medical organizations have begun using low-cost biosensors to monitor food and water toxins, human biological processes, accurate health diagnostics, and for other applications [43]. Biosensor-based technologies are essential to assess samples

• precisely in modern medical equipment [44]. Biosensors are now transitioning from laboratory-based systems to distributed health care. Traditional scientific diagnosis involves taking a sample from the patient and sending it to an analytical laboratory. In these point-of-care tests, the patient has to wait

Interface properties of nanostructured carbon-coated biological implants: an overview

• Mattia Bartoli,
• Francesca Cardano,
• Erik Piatti,
• Stefania Lettieri,
• Andrea Fin and
• Alberto Tagliaferro

Beilstein J. Nanotechnol. 2024, 15, 1041–1053, doi:10.3762/bjnano.15.85

• between medical implants and living tissues are of great complexity because of the simultaneous occurrence of a wide variety of phenomena. The engineering of implant surfaces represents a crucial challenge in material science, but the further improvement of implant properties remains a critical task. It

• nanostructured carbon coatings (nanodiamonds, carbon nanotubes, and graphene-related materials) for the improvement of the overall properties of medical implants. We are focusing on biological interactions, improved corrosion resistance, and overall mechanical properties, trying to provide a complete overview

• to describe the study of materials at the nanoscale [2]. Afterwards, nanosized and nanostructured carbon species have attracted great interest thanks to their intrinsic properties and easy functionalization [3]. The utilization of nanocarbon species has been widely deployed in advanced medical

Recent progress on field-effect transistor-based biosensors: device perspective

• Billel Smaani,
• Fares Nafa,
• Mohamed Salah Benlatrech,
• Ismahan Mahdi,
• Hamza Akroum,
• Mohamed walid Azizi,
• Khaled Harrar and
• Sayan Kanungo

Beilstein J. Nanotechnol. 2024, 15, 977–994, doi:10.3762/bjnano.15.80

• 10.3762/bjnano.15.80 Abstract Over the last few decades, field-effect transistor (FET)-based biosensors have demonstrated great potential across various industries, including medical, food, agriculture, environmental, and military sectors. These biosensors leverage the electrical properties of transistors

• devices have gained significant importance across various domains, including the medical field, environmental monitoring, and the agricultural sector (Figure 1) [1][2]. In this context, biosensors have found widespread application in industries, particularly for food quality control and safety [3]. They

• , biosensors have been extensively utilized in the field of medical sciences and clinical diagnostics [14]. They have been employed in cancer diagnosis [15], cardiovascular studies [16], and diabetes monitoring [17]. The application of biosensors in cancer diagnosis and therapy is very important due to the

When nanomedicines meet tropical diseases

• Eder Lilia Romero,
• Katrien Van Bocxlaer and
• Fabio Rocha Formiga

Beilstein J. Nanotechnol. 2024, 15, 830–832, doi:10.3762/bjnano.15.69

• Eder Lilia Romero Katrien Van Bocxlaer Fabio Rocha Formiga Nanomedicine Research and Development Centre (NARD), Science and Technology Department, National University of Quilmes, Roque Saenz Peña 352, B1876 Bernal, Provincia de Buenos Aires, Argentina Skin Research Centre, Hull York Medical School

• , York Biomedical Research Institute, University of York, York YO10 5DD, UK Aggeu Magalhães Institute, Oswaldo Cruz Foundation (FIOCRUZ), 50670-420, Recife, PE, Brazil Faculty of Medical Sciences, University of Pernambuco (UPE), 52171-011, Recife, PE, Brazil 10.3762/bjnano.15.69 Keywords: Aedes aegypti

Intermixing of MoS₂ and WS₂ photocatalysts toward methylene blue photodegradation

• Maryam Al Qaydi,
• Nitul S. Rajput,
• Michael Lejeune,
• Abdellatif Bouchalkha,
• Mimoun El Marssi,
• Steevy Cordette,
• Chaouki Kasmi and
• Mustapha Jouiad

Beilstein J. Nanotechnol. 2024, 15, 817–829, doi:10.3762/bjnano.15.68

• removal, or synthetic dye degradation [4][5][6]. For instance, methylene blue (MB), which is considered one of the most used synthetic organic dyes in various industrial and medical applications, poses serious risks as a pollutant to water resources [7]. Indeed, MB is a potential carcinogen and mutagen

Electrospun polysuccinimide scaffolds containing different salts as potential wound dressing material

• Veronika Pálos,
• Krisztina S. Nagy,
• Rita Pázmány,
• Krisztina Juriga-Tóth,
• Bálint Budavári,
• Judit Domokos,
• Dóra Szabó,
• Ákos Zsembery and
• Angela Jedlovszky-Hajdu

Beilstein J. Nanotechnol. 2024, 15, 781–796, doi:10.3762/bjnano.15.65

• of Medical Microbiology, Semmelweis University, Nagyvárad tér 4, 1089, Budapest, Hungary Department of Oral Biology, Semmelweis University, Nagyvárad tér 4, 1089, Budapest, Hungary 10.3762/bjnano.15.65 Abstract In this research, we applied electrospinning to create a two-component biodegradable

• Polymer mixtures contain at least one component besides the polymer, such as nanoparticles, inorganic salts, or other polymers. These types of polymer mixtures are used for medical purposes; for example, metronidazole/poly(ε-caprolactone) (PCL)/alginate for dental implants or poly(lactic acid

• , including strength and elasticity of the fibrous scaffold, are crucial parameters. Medical gauze has a storage modulus of 1 MPa to 1 GPa [58], while the Young’s modulus of the skin is between 0.1 and 10 kPa, depending on the body parts, layer, and skin age [59]. In our research, we aimed to investigate the

Exfoliation of titanium nitride using a non-thermal plasma process

• Priscila Jussiane Zambiazi,
• Dolores Ribeiro Ricci Lazar,
• Larissa Otubo,
• Rodrigo Fernando Brambilla de Souza,
• Almir Oliveira Neto and
• Cecilia Chaves Guedes-Silva

Beilstein J. Nanotechnol. 2024, 15, 631–637, doi:10.3762/bjnano.15.53

• conductivity [10][11][12]. On the nanoscale, TiN finds applications as additive in titanium alloys, as catalyst support material, as supercapacitor component, and as nanocoating for medical implants [13][14][15][16]. Furthermore, ultra-small TiN nanodots have been successfully obtained through liquid

Radiofrequency enhances drug release from responsive nanoflowers for hepatocellular carcinoma therapy

• Yanyan Wen,
• Ningning Song,
• Yueyou Peng,
• Weiwei Wu,
• Qixiong Lin,
• Minjie Cui,
• Rongrong Li,
• Qiufeng Yu,
• Sixue Wu,
• Yongkang Liang,
• Wei Tian and
• Yanfeng Meng

Beilstein J. Nanotechnol. 2024, 15, 569–579, doi:10.3762/bjnano.15.49

• Yanyan Wen Ningning Song Yueyou Peng Weiwei Wu Qixiong Lin Minjie Cui Rongrong Li Qiufeng Yu Sixue Wu Yongkang Liang Wei Tian Yanfeng Meng School of Public Health, Shanxi Medical University, Taiyuan, Shanxi 030001, China College of Medical Imaging, Shanxi Medical University, Taiyuan, Shanxi

• , 030001, China Department of Radiology, Taiyuan Central Hospital of Shanxi Medical University, Taiyuan, Shanxi 030009, China The Ninth Clinical Medical School of Shanxi Medical University, Taiyuan, Shanxi 030009, China Department of Medical Imaging, Changzhi Medical College, Changzhi, Shanxi, 046000

• , China Academy of Medical Sciences, Shanxi Medical University, Taiyuan, Shanxi 030001, China Department of General Surgery, Shanxi Cardiovascular Hospital, Taiyuan, Shanxi 030024, China 10.3762/bjnano.15.49 Abstract Hepatocellular carcinoma (HCC) is the sixth most common malignant tumor and the third

Heat-induced morphological changes in silver nanowires deposited on a patterned silicon substrate

• Elyad Damerchi,
• Sven Oras,
• Edgars Butanovs,
• Allar Liivlaid,
• Mikk Antsov,
• Boris Polyakov,
• Annamarija Trausa,
• Veronika Zadin,
• Andreas Kyritsakis,
• Loïc Vidal,
• Karine Mougin,
• Siim Pikker and
• Sergei Vlassov

Beilstein J. Nanotechnol. 2024, 15, 435–446, doi:10.3762/bjnano.15.39

• ; silver nanowires; Introduction Metal nanowires (NWs) are promising key elements in a wide range of applications, including solar cells [1], smart windows [2], flexible sensors [3], touch screens [4], biocompatible polymer binders [5], temperature sensing [6], medical materials [7], and key elements of

Potential of a deep eutectic solvent in silver nanoparticle fabrication for antibiotic residue detection

• Le Hong Tho,
• Bui Xuan Khuyen,
• Ngoc Xuan Dat Mai and
• Nhu Hoa Thi Tran

Beilstein J. Nanotechnol. 2024, 15, 426–434, doi:10.3762/bjnano.15.38

• ], and other analytical measurements regarding food, medical, and environmental issues [12][13][14]. Undeniably, SERS is the future for sensor design. So far, most achievements regarding SERS rely on the development of plasmonic materials. Noble metals (e.g., Au, Ag, and Cu) are the most important group

Exploring the relationships between physiochemical properties of nanoparticles and cell damage to combat cancer growth using simple periodic table-based descriptors

• Joyita Roy and
• Kunal Roy

Beilstein J. Nanotechnol. 2024, 15, 297–309, doi:10.3762/bjnano.15.27

• biocompatibility on NP toxicity. These properties of NPs determine their toxicity and interaction with the cell membrane damaging human health and the environment [12]. The toxic effect of NPs can be used as a medical treatment for diseases at the cellular level, that is, targeting and destroying cancerous cells

• graphs for both cell damage and zeta potential data. Supporting Information File 33: Additional experimental data. Supporting Information File 34: Additional figures. Funding JR thankfully acknowledges Indian Council of Medical Research (ICMR), New Delhi for supporting financially to the work in the

Ultrasensitive and ultrastretchable metal crack strain sensor based on helical polydimethylsiloxane

• Shangbi Chen,
• Dewen Liu,
• Weiwei Chen,
• Huajiang Chen,
• Jiawei Li and
• Jinfang Wang

Beilstein J. Nanotechnol. 2024, 15, 270–278, doi:10.3762/bjnano.15.25

• ], monitoring human health [6][7][8], medical treatment [9][10], soft robotics [11][12], and human–computer interaction [13][14][15]. Numerous flexible strain sensors employing various mechanisms such as piezoresistivity [16][17], capacitance [18][19], and piezoelectricity have been developed to fulfill the

• from the taobao shopping platform. The medical rubber gloves and injection syringes were procured from a local hospital (Shanghai, China). The titanium (Ti) target (99.99%) utilized for the adhesion layer was purchased from Deyang Ona New Materials Co., Ltd. The gold (Au) target (99.999%) employed for

Multiscale modelling of biomolecular corona formation on metallic surfaces

• Parinaz Mosaddeghi Amini,
• Ian Rouse,
• Julia Subbotina and
• Vladimir Lobaskin

Beilstein J. Nanotechnol. 2024, 15, 215–229, doi:10.3762/bjnano.15.21

• shown that ripened cheese and cheese spreads acquire a higher aluminum content as compared to other milk products [6]. Aside from wrapping and container packaging, aluminum has found a wide popularity in other applications, such as manufacturing of kitchen utensils, cosmetics, and components for medical

• corona content and optimize the processes in food and chemical industry. The presented methodology can be easily extended to other molecules, materials, and contexts involving the bionano interface such as environmental safety, health, medical devices, or toxicology. Schematic representation of the life

New application of bimetallic Ag/Pt nanoplates in a colorimetric biosensor for specific detection of E. coli in water

• Azam Bagheri Pebdeni,
• Mohammad N. AL-Baiati and
• Morteza Hosseini

Beilstein J. Nanotechnol. 2024, 15, 95–103, doi:10.3762/bjnano.15.9

• Department of Pharmaceutical Biomaterials and Medicinal Biomaterials Research Center,Faculty of Pharmacy, Tehran University of Medical Sciences, Tehran, Iran 10.3762/bjnano.15.9 Abstract A fast and sensitive aptasensor was developed using nanoplates with peroxidase activity as a novel approach. E. coli

• . However, these procedures need a significant amount of time, skilled operators, and costly equipment. As a result, for effective medical treatment with minimal detection time, a selective and sensitive detection strategy is required [5][6]. New nanoparticles for fast bacterial detection can be fabricated

• study was supported by the research Council of the University of Tehran and Tehran University of Medical Sciences. The authors are thankful for the financial support.

Berberine-loaded polylactic acid nanofiber scaffold as a drug delivery system: The relationship between chemical characteristics, drug-release behavior, and antibacterial efficiency

• Le Thi Le,
• Hue Thi Nguyen,
• Liem Thanh Nguyen,
• Huy Quang Tran and
• Thuy Thi Thu Nguyen

Beilstein J. Nanotechnol. 2024, 15, 71–82, doi:10.3762/bjnano.15.7

• , nanofiber scaffolds can act as a multifunctional tool in medical treatments, combining drug release for disease therapy, cell proliferation, wound healing, and antimicrobial effect [21][22][23][24][25]. Nanofibers of PLA functionalized with laponite (LAP)/amoxicillin (AMX) prolonged the drug release up to