In situ optical sub-wavelength thickness control of porous anodic aluminum oxide

• Aleksandrs Dutovs,
• Raimonds Popļausks,
• Oskars Putāns,
• Vladislavs Perkanuks,
• Aušrinė Jurkevičiūtė,
• Tomas Tamulevičius,
• Uldis Malinovskis,
• Iryna Olyshevets,
• Donats Erts and
• Juris Prikulis

Beilstein J. Nanotechnol. 2024, 15, 126–133, doi:10.3762/bjnano.15.12

• zinc oxide nanorods embedded within the PAAO template [13]. Recently, it was demonstrated that the PAAO thickness tuning can increase the signal intensity and refractometric sensitivity of localized surface plasmon resonance (LSPR) sensors constructed using gold nanoparticles, which are deposited on

• the pore openings of the PAAO [16]. An influence of PAAO thickness variation in the range from 500 nm to 5 μm on biosensor performance using gold-capped PAAO has been reported [17]. Usually, the PAAO thickness is determined by the anodization time and growth rate. Although the thickness accuracy can

New application of bimetallic Ag/Pt nanoplates in a colorimetric biosensor for specific detection of E. coli in water

• Azam Bagheri Pebdeni,
• Mohammad N. AL-Baiati and
• Morteza Hosseini

Beilstein J. Nanotechnol. 2024, 15, 95–103, doi:10.3762/bjnano.15.9

• illness cases worldwide each year [1][2]. Water quality testing is based on the presence of E. coli, which is still regarded as the best indication of fecal contamination [3][4]. There are several methods for detecting bacteria (e.g., ELISA and PCR) with colony counting serving as the gold standard

• was measured using UV–vis spectroscopy at a wavelength of 600 nm (OD600). The gold standard method of plate counting was used to estimate the number of bacterial cells. Detection of E. coli for bacterial assays Following the optimization of the experimental settings, various concentrations of E. coli

Berberine-loaded polylactic acid nanofiber scaffold as a drug delivery system: The relationship between chemical characteristics, drug-release behavior, and antibacterial efficiency

• Le Thi Le,
• Hue Thi Nguyen,
• Liem Thanh Nguyen,
• Huy Quang Tran and
• Thuy Thi Thu Nguyen

Beilstein J. Nanotechnol. 2024, 15, 71–82, doi:10.3762/bjnano.15.7

• been employed to produce nanoformulations of drugs for endowing a better therapeutic effect. The nanoformulations for drug delivery can be designed using nanocarrier systems, including organic materials (liposomes, nanoemulsions, nanomicelles, and nanofibers) and inorganic nanoparticles (gold, silver

Influence of conductive carbon and MnCo₂O₄ on morphological and electrical properties of hydrogels for electrochemical energy conversion

• Sylwia Pawłowska,
• Karolina Cysewska,
• Yasamin Ziai,
• Jakub Karczewski,
• Piotr Jasiński and
• Sebastian Molin

Beilstein J. Nanotechnol. 2024, 15, 57–70, doi:10.3762/bjnano.15.6

• appropriate electrical conductivity [22]. Suspension of conductive fillers in the hydrogel structure, such as metallic particles (gold nanoparticles, silver nanoparticles) [23][24][25], carbon-based materials (GO graphene oxide, CNT carbon nanotubes) [26][27][28], and conductive polymers (polyaniline

• surface for the sample Hgel-MCO-cCB 1:3 showed the presence of MCO and cCB particles in the hydrogel scaffold, confirming their entrapment in the polymer matrix (Figure 1b and Figure 1e). A similar composite structure with gold nanorods suspended in the PNIPAAm matrix was observed by Nakielski et al. [47

• an accelerating voltage of 10 kV. Before imaging, the hydrogel samples were freeze-dried and coated with a 10 nm gold layer. The chemical composition of the hydrogel was analysed with a Thermo Fisher Scientific silicon drift detector energy-dispersive X-ray spectroscope. For characterisation of the

Curcumin-loaded nanostructured systems for treatment of leishmaniasis: a review

• Douglas Dourado,
• Thayse Silva Medeiros,
• Éverton do Nascimento Alencar,
• Edijane Matos Sales and
• Fábio Rocha Formiga

Beilstein J. Nanotechnol. 2024, 15, 37–50, doi:10.3762/bjnano.15.4

• , assembly, and optical properties [113]. These nanoformulations can be synthesized through chemical, physical, or biological processes and are solely generated from metal precursors such as silver and gold [114][115]. In addition, MNPs have been widely used in therapy, drug delivery, targeting, and imaging

• [116][117]. Current studies have directed the use of metallic nanoparticles such as silver and gold nanoparticles against Leishmania sp. [118]. As silver and gold nanoparticles can produce reactive oxygen species (ROS) and Leishmania is known to be extremely sensitive to these compounds, these have

• curc-coated gold nanoparticles (curc-AuNPs) against L. major [125]. The NPs showed spherical morphology, particle size of 22 nm, and adequate polydispersity. Curc-AuNPs revealed IC50 values against L. major promastigotes of 64.79 μg/mL and 29.89 μg/mL in 24 h and 48 h, respectively. Additionally, they

Nanotechnological approaches in the treatment of schistosomiasis: an overview

• Lucas Carvalho,
• Michelle Sarcinelli and
• Beatriz Patrício

Beilstein J. Nanotechnol. 2024, 15, 13–25, doi:10.3762/bjnano.15.2

• established criteria were identified. Inorganic and polymeric nanoparticles were the most prevalent nanosystems used. Gold was the primary material used to produce inorganic nanoparticles, while poly(lactic-co-glycolic acid) and chitosan were commonly used to produce polymeric nanoparticles. None of these

• ) are derived from metals or silica [25]. The most common metal used in the production of IN found in this work was gold, even though it was also possible to observe a great amount of works using silver and zinc (Figure 5). While silica-derived nanoparticles are used in the treatment against

• ]. Therefore, metallic nanoparticles also have a curative role against schistosomiasis. A possible explanation for this action was suggested by Dkhil et al. in their work with gold nanoparticles [27]. They suggested that their curative effects are due to antioxidant properties which confer the ability to

A combined gas-phase dissociative ionization, dissociative electron attachment and deposition study on the potential FEBID precursor [Au(CH₃)₂Cl]₂

• Elif Bilgilisoy,
• Ali Kamali,
• Thomas Xaver Gentner,
• Gerd Ballmann,
• Sjoerd Harder,
• Hans-Peter Steinrück,
• Hubertus Marbach and
• Oddur Ingólfsson

Beilstein J. Nanotechnol. 2023, 14, 1178–1199, doi:10.3762/bjnano.14.98

• fabrication of functional gold nanostructures for application in plasmonic and detector technology, we conducted a comprehensive study on [Au(CH3)2Cl]2 as a potential precursor for such depositions. Fundamental electron-induced dissociation processes were studied under single collision conditions, and the

• yielded deposits with high gold content, ranging from 45 to 61 atom % depending on the beam current and on the cleanliness of the substrates surface. Keywords: dissociative electron attachment; dissociative ionization; focused-electron-beam-induced deposition (FEBID); gold deposit; low-energy electrons

• ; quantum chemical calculation; ultrahigh vacuum; Introduction In recent years, gold nanostructures have received much attention owing to their dielectric properties [1], their biocompatibility [2], and their electrical properties [3][4], which enable a multitude of exciting applications in the field of

Spatial variations of conductivity of self-assembled monolayers of dodecanethiol on Au/mica and Au/Si substrates

• Julian Skolaut,
• Jędrzej Tepper,
• Federica Galli,
• Wulf Wulfhekel and
• Jan M. van Ruitenbeek

Beilstein J. Nanotechnol. 2023, 14, 1169–1177, doi:10.3762/bjnano.14.97

• electronics. A common test bed for fundamental investigations on how to acquire this conductivity are alkanethiol layers on gold substrates. A widely used approach in measuring the conductivity of a molecular layer is conductive atomic force microscopy. Using this method, we investigate the influence of a

• rougher and a flatter gold substrate on the lateral variation of the conductivity. We find that the roughness of the substrate crucially defines this variation. We conclude that it is paramount to adequately choose a gold substrate for investigations on molecular layer conductivity. Keywords: Au/mica; Au

• the Au surface. They are produced in the process of SAM formation by sulfur–gold bonds, which result in removing Au atoms from the top layer. This leaves the surface with Au atom vacancies that arrange into small islands of a few nanometers in size. This size matches the darker areas observed in the

Hierarchically patterned polyurethane microgrooves featuring nanopillars or nanoholes for neurite elongation and alignment

• Lester Uy Vinzons,
• Guo-Chung Dong and
• Shu-Ping Lin

Beilstein J. Nanotechnol. 2023, 14, 1157–1168, doi:10.3762/bjnano.14.96

• holes. The enhancement of PC12 neurite elongation observed here is similar to that previously reported on SU-8 nanoholes (around 250 nm in diameter and 50 nm in spacing) [6] and different from that on gold nanopillars (around 230 nm in diameter and 70 nm in spacing) and nanopores (around 200 nm in

A multi-resistance wide-range calibration sample for conductive probe atomic force microscopy measurements

• François Piquemal,
• Khaled Kaja,
• Pascal Chrétien,
• José Morán-Meza,
• Frédéric Houzé,
• Christian Ulysse and
• Abdelmounaim Harouri

Beilstein J. Nanotechnol. 2023, 14, 1141–1148, doi:10.3762/bjnano.14.94

• -AFM imaging and I–V curves measurement to define the conditions for calibrated measurements. Calibration sample design and fabrication The sample developed in this work consisted of a square fused silica substrate (11 mm wide, 2 mm thick), on which gold connection lines and pads were fabricated by

• standard photolithography, using a mask aligner (MA6, Karl Suss, Germany), and conventional deposition techniques. Following a resist (about 1 µm thick) development process, a 2 inch diameter wafer was placed in a vacuum chamber for electron beam deposition of a 200 nm thick titanium/gold layer

• . Subsequently, a lift-off process in acetone was employed to reveal the gold pattern. Finally, square samples were cut to match the dimensions of the measurement setup. We hand-soldered thick-film surface-mounted-device (SMD) resistors onto the connection gold pads on the surface using small soldering paste

Curcumin-loaded albumin submicron particles with potential as a cancer therapy: an in vitro study

• Nittiya Suwannasom,
• Netsai Sriaksorn,
• Chutamas Thepmalee,
• Krissana Khoothiam,
• Ausanai Prapan,
• Hans Bäumler and
• Chonthida Thephinlap

Beilstein J. Nanotechnol. 2023, 14, 1127–1140, doi:10.3762/bjnano.14.93

• . Moreover, after 48 h, both free CUR and CUR-HSA-MPs exhibit stronger toxic effects against Huh-7 than against MCF-7 cells. In line with earlier studies on CUR-loaded gold/chitosan nanogels, a higher concentration-dependent cell viability reduction is induced in Huh-7 cells than in MCF-7 cancerous cells [44

• morphology of the particles was examined in a JSM-5910 SEM (JEOL USA, Peabody, MA, USA). The microparticle samples were diluted in distilled water, and a drop of the particle suspension was applied on copper tape and then allowed to dry at RT overnight. The dried samples were then sputter-coated with gold

Density functional theory study of Au-fcc/Ge and Au-hcp/Ge interfaces

• Olga Sikora,
• Małgorzata Sternik,
• Benedykt R. Jany,
• Franciszek Krok,
• Przemysław Piekarz and
• Andrzej M. Oleś

Beilstein J. Nanotechnol. 2023, 14, 1093–1105, doi:10.3762/bjnano.14.90

• , Poland 10.3762/bjnano.14.90 Abstract In recent years, nanostructures with hexagonal polytypes of gold have been synthesised, opening new possibilities in nanoscience and nanotechnology. As bulk gold crystallizes in the fcc phase, surface effects can play an important role in stabilizing hexagonal gold

• nanostructures. Here, we investigate several heterostructures with Ge substrates, including the fcc and hcp phases of gold that have been observed experimentally. We determine and discuss their interfacial energies and optimized atomic arrangements, comparing the theory results with available experimental data

• structure; hexagonal gold; interface energy; Introduction Heterophase interfaces are responsible for unique properties of many advanced devices designed for electronics and other applications [1]. Understanding the formation and energetics of interfaces is highly important for the nucleation of new

Properties of tin oxide films grown by atomic layer deposition from tin tetraiodide and ozone

• Kristjan Kalam,
• Peeter Ritslaid,
• Tanel Käämbre,
• Aile Tamm and
• Kaupo Kukli

Beilstein J. Nanotechnol. 2023, 14, 1085–1092, doi:10.3762/bjnano.14.89

• photocurrent and normalising the signal to a reference photocurrent signal from a clean gold mesh located behind the last optical element of the beamline. Results and Discussion To establish the evaporator temperature that provides the maximum coverage of substrate surface with precursor molecules and

Exploring internal structures and properties of terpolymer fibers via real-space characterizations

• Michael R. Roenbeck and
• Kenneth E. Strawhecker

Beilstein J. Nanotechnol. 2023, 14, 1004–1017, doi:10.3762/bjnano.14.83

• extracted from a 65 decitex yarn. Fibers were mounted onto cardstock specimen holders, fixed with adhesive at two points approximately 15 mm apart from one another, and conductively coated with a gold–palladium mixture to mitigate sample drift, for example, due to sample charging effects inside the FIB

Nanoarchitectonics of photothermal materials to enhance the sensitivity of lateral flow assays

• Elangovan Sarathkumar,
• Rajasekharan S. Anjana and
• Ramapurath S. Jayasree

Beilstein J. Nanotechnol. 2023, 14, 988–1003, doi:10.3762/bjnano.14.82

• assays (LFAs) are currently the most widely used point-of-care testing technique with remarkable advantages such as simple operation, rapid analysis, portability, and low cost. Traditionally, gold nanoparticles are employed as tracer element in LFAs due to their strong localised surface plasmon resonance

• different parts, namely sample pad, conjugate pad, nitrocellulose membrane, and adsorbent pad, maintaining a smooth flow of reagents through the LFA membrane. In the presence of a sample, the analyte initially reacts with affinity molecules, commonly antibodies linked with tracers such as gold nanoparticles

• , before being captured by immobilized biomolecules on a test line in the nitrocellulose membrane [6][7]. In conventional LFAs, most commonly gold nanoparticles and coloured cellulose nanobeads have been used as tracer elements because of strong light absorption and surface plasmon resonance, which yield

Antibody-conjugated nanoparticles for target-specific drug delivery of chemotherapeutics

• Mamta Kumari,
• Amitabha Acharya and
• Praveen Thaggikuppe Krishnamurthy

Beilstein J. Nanotechnol. 2023, 14, 912–926, doi:10.3762/bjnano.14.75

• Herceptin® to improve cellular uptake and cytotoxicity in breast cancer cells [41]. Similarly, Rayavarapu et al. conjugated HER2 antibodies on the surface of gold nanoparticles using a noncovalent conjugation method in order to increase intracellular uptake into cancer cells [42]. The adsorption results

• enhanced humoral immune response. The protein corona formation on Ab-conjugated NPs mediates a more specific and sensitive antibody–antigen interaction [83]. The group of de Puig evaluated the effect of a protein corona on anti-NS1 Ab-conjugated star-shaped gold NPs. They found that the protein corona

N-Heterocyclic carbene-based gold etchants

• Robert B. Chevalier,
• Justin Pantano,
• Matthew K. Kiesewetter and
• Jason R. Dwyer

Beilstein J. Nanotechnol. 2023, 14, 865–871, doi:10.3762/bjnano.14.71

• self-assembled monolayers (SAMs) on gold. We examined several different species that have been used to produce NHC-based monolayers on gold, namely 1,3-diisopropyl-5-nitrobenzimidazolium iodide, 1,3-diisopropyl-5-nitrobenzimidazolium hydrogen carbonate, bis(1,3-diisopropyl-5-nitrobenzimidazolium)gold(I

• ) iodide, and 1,3-diisopropyl-5-nitrobenzimidazole-2-ylidene. Contrary to expectation, solutions containing the first two species in tetrahydrofuran and dichloromethane caused visible loss of gold from thin-film-coated glass slides. The use of toluene solutions of all species resulted in no apparent

• dissolution of gold. We present scanning electron micrographs and elemental imaging analyses by energy dispersive X-ray spectroscopy to examine the effect of solutions of each species on the gold film. This work highlights the risk of unwanted etching during some routes to NHC-based surface functionalization

Silver nanoparticles loaded on lactose/alginate: in situ synthesis, catalytic degradation, and pH-dependent antibacterial activity

• Nguyen Thi Thanh Tu,
• T. Lan-Anh Vo,
• T. Thu-Trang Ho,
• Kim-Phuong T. Dang,
• Van-Dung Le,
• Phan Nhat Minh,
• Chi-Hien Dang,
• Vinh-Thien Tran,
• Van-Su Dang,
• Tran Thi Kim Chi,
• Hieu Vu-Quang,
• Radek Fajgar,
• Thi-Lan-Huong Nguyen,
• Van-Dat Doan and
• Thanh-Danh Nguyen

Beilstein J. Nanotechnol. 2023, 14, 781–792, doi:10.3762/bjnano.14.64

• 73.9 ± 19.2 nm and 80.2 ± 24.1 nm for AgNPs@Lac/Alg-0.3 and AgNPs@Lac/Alg-0.7, respectively. These findings are consistent with a previous study on the synthesis of gold nanoparticles using this nanocomposite [37]. Figure 4 presents the FTIR spectra of the AgNPs@Lac/Alg nanocomposites. Both spectra

Metal-organic framework-based nanomaterials as opto-electrochemical sensors for the detection of antibiotics and hormones: A review

• Akeem Adeyemi Oladipo,
• Saba Derakhshan Oskouei and
• Mustafa Gazi

Beilstein J. Nanotechnol. 2023, 14, 631–673, doi:10.3762/bjnano.14.52

• the sensor. A novel electrochemical aptasensor based on Fe MOFs was reported by Song and co-workers [70]. In order to increase the sensor’s sensitivity to the detection of antibiotics, the MOF was further modified using carbon nanofibres and gold nanoparticles using a variety of techniques. In the

• signals are obtained, the likelihood of inaccurate results is reduced. For example, Rani et al. [50] synthesised a gold nanoparticle-decorated amine-functionalized Zr-MOF through a solvothermal synthesis process in order to detect nitrofurazone antibiotics via dual-mode (opto-electrochemical) sensing

SERS performance of GaN/Ag substrates fabricated by Ag coating of GaN platforms

• Magdalena A. Zając,
• Bogusław Budner,
• Malwina Liszewska,
• Bartosz Bartosewicz,
• Łukasz Gutowski,
• Jan L. Weyher and
• Bartłomiej J. Jankiewicz

Beilstein J. Nanotechnol. 2023, 14, 552–564, doi:10.3762/bjnano.14.46

• reliable SERS substrates, which often must be tailored toward specific applications [15][17][18]. The SERS substrates described in the literature include nanoparticles, core–shell nanoparticles, semicontinuous metal films, and many other nanostructures most commonly made of gold or silver [18][19][20][21

The origin of black and white coloration of the Asian tiger mosquito Aedes albopictus (Diptera: Culicidae)

• Manuela Rebora,
• Gianandrea Salerno,
• Silvana Piersanti,
• Alexander Kovalev and
• Stanislav N. Gorb

Beilstein J. Nanotechnol. 2023, 14, 496–508, doi:10.3762/bjnano.14.41

• (Hitachi High-Technologies Corp., Tokyo, Japan) at 3 kV acceleration voltage. Specimens were sputter-coated with gold/palladium (10 nm layer thickness). In a similar manner to a procedure from [33], for cryo-SEM, insect samples were either glued with Tissue-Tek® O.C.T.TM Compound (Sakura® Finetek Europe

• knife in the cryo-stage preparation chamber, were sputter-coated with gold/palladium (6 nm thickness) and examined under freeze conditions (−120 °C) in the SEM Hitachi S-4800 at 3 kV acceleration voltage. Sputter-coated samples were also used to demonstrate the modulation of the light reflection

Plasmonic nanotechnology for photothermal applications – an evaluation

• A. R. Indhu,
• L. Keerthana and
• Gnanaprakash Dharmalingam

Beilstein J. Nanotechnol. 2023, 14, 380–419, doi:10.3762/bjnano.14.33

• of electrons and holes for Al, Ag, Au, and Cu. This distribution takes the characteristic of a symmetric/continuous distribution of electrons and holes in aluminium, a bimodal distribution in silver, and an antisymmetric hole-dominant distribution in copper and gold. Also, decreasing the thickness of

• elements, nanospheres of gold, silver, platinum, cobalt, zinc, nickel, titanium, copper, aluminium, molybdenum, vanadium, and palladium have been analysed [98]. Although there were assumptions of homogeneity, sphericity, and no interaction between particles, the Mie theory-based scattering cross sections

Quercetin- and caffeic acid-functionalized chitosan-capped colloidal silver nanoparticles: one-pot synthesis, characterization, and anticancer and antibacterial activities

• Akif Hakan Kurt,
• Elif Berna Olutas,
• Fatma Avcioglu,
• Hamza Karakuş,
• Mehmet Ali Sungur,
• Cansu Kara Oztabag and
• Muhammet Yıldırım

Beilstein J. Nanotechnol. 2023, 14, 362–376, doi:10.3762/bjnano.14.31

• , caffeic acid has also been reported to have antiviral, anticoagulant, anti-inflammatory, antibacterial, and anticancer activities [31][32][33][34]. Silver nanoparticles are an important example of different types of nanomaterials (copper, zinc, titanium, magnesium, gold, and alginate) that have been

Nanotechnology – a robust tool for fighting the challenges of drug resistance in non-small cell lung cancer

• Filip Gorachinov,
• Fatima Mraiche,
• Diala Alhaj Moustafa,
• Ola Hishari,
• Yomna Ismail,
• Jensa Joseph,
• Maja Simonoska Crcarevska,
• Marija Glavas Dodov,
• Nikola Geskovski and
• Katerina Goracinova

Beilstein J. Nanotechnol. 2023, 14, 240–261, doi:10.3762/bjnano.14.23

• , gold nanoshells, and microbots) and imaging contrast nanoparticles (quantum dots and iron oxide), after homing into the tumor environment [113]. Xu et al. described an injectable nanoparticle generator (iNPG) showing substantial natural tumor tropism designed as aminopropyltriethoxysilane (APTES

Concentration-dependent photothermal conversion efficiency of gold nanoparticles under near-infrared laser and broadband irradiation

• Vikas,
• Raj Kumar and
• Sanjeev Soni

Beilstein J. Nanotechnol. 2023, 14, 205–217, doi:10.3762/bjnano.14.20

• Organisation, Sector-30C, Chandigarh-160030, India 10.3762/bjnano.14.20 Abstract The photothermal conversion efficiency of gold different nanoparticles (GNPs) in different concentrations (1.25–20 µg/mL) and at different irradiation intensities of near-infrared (NIR) broadband and NIR laser irradiation is

• evaluated. Results show that for a concentration of 20.0 µg/mL, 40 nm gold nanospheres, 25 × 47 nm gold nanorods (GNRs), and 10 × 41 nm GNRs show a 4–110% higher photothermal conversion efficiency under NIR broadband irradiation than under NIR laser irradiation. Broadband irradiation seems suitable to

• applications. Keywords: broadband irradiation; gold nanoparticles; laser; near-infrared; photothermal conversion efficiency; plasmonics; Introduction Plasmonic photothermal properties of gold nanoparticles (GNPs) are useful for a variety of applications including those in biomedicine, such as drug delivery