Nanomaterials for biomedical applications

• Iqra Zainab,
• Zohra Naseem,
• Syeda Rubab Batool,
• Filippo Pierini,
• Seda Kizilel and
• Muhammad Anwaar Nazeer

Beilstein J. Nanotechnol. 2025, 16, 1499–1503, doi:10.3762/bjnano.16.105

• used in the future for tissue recovery, which was previously thought to be beyond repair [31]. In addition to diagnosis and tissue regeneration, nanomaterials can create new treatment methods and enhance the design and performance of medical implants. An area that is getting a lot of attention is

Laser processing in liquids: insights into nanocolloid generation and thin film integration for energy, photonic, and sensing applications

• Akshana Parameswaran Sreekala,
• Pooja Raveendran Nair,
• Jithin Kundalam Kadavath,
• Bindu Krishnan,
• David Avellaneda Avellaneda,
• M. R. Anantharaman and
• Sadasivan Shaji

Beilstein J. Nanotechnol. 2025, 16, 1428–1498, doi:10.3762/bjnano.16.104

• medium characteristics (e.g., chemical composition and viscosity) influence the size, morphology, and surface properties of the Au NPs, which, in turn, determine their performance. The effect of solvents on morphology of generated NPs in laser ablation is shown in Figure 2. While PLAL offers a rich

• , suggesting that careful control of size reduction and surface properties is critical for optimizing photocatalyst performance, especially in water splitting applications. Further investigation is necessary to refine the process and mitigate the negative effects of fragmentation. LFL is a highly versatile

• has emerged as a powerful approach to fabricate advanced heterostructures and integrated electrode architectures, which are challenging to achieve through conventional synthesis methods in the development of high-performance energy storage and conversion devices [85][88][92][93][94][95][96]. The

Photochemical synthesis of silver nanoprisms via green LED irradiation and evaluation of SERS activity

• Tuan Anh Mai-Ngoc,
• Nhi Kieu Vo,
• Cong Danh Nguyen,
• Thi Kim Xuan Nguyen and
• Thanh Sinh Do

Beilstein J. Nanotechnol. 2025, 16, 1417–1427, doi:10.3762/bjnano.16.103

• ] SERS substrates by impregnating them with silver nanostructures. While many efforts have been devoted to the synthesis of AgNPrs and evaluation of their SERS activity, limited studies have focused on the SERS performance of photochemically synthesized AgNPrs, particularly in 4-mercaptobenzoic acid (4

• yield. The SERS performance of the synthesized AgNPrs, evaluated using 4-MBA as a probe molecule, demonstrated significantly enhanced Raman signals compared to the initial AgNPs seeds, highlighting their potential applicability in SERS-based sensors. Results and Discussion Synthesis of seeds The UV–vis

• confirm that AgNPrs exhibited superior SERS performance, consistent with prior studies investigating the direct SERS detection of 4-MBA [18][19]. Due to their anisotropic structure, AgNPrs concentrate surface electrons and form electromagnetic “hot spots” at the edges and tip of the nanoprisms [22][24][25

The role of biochar in combating microplastic pollution: a bibliometric analysis in environmental contexts

• Tuan Minh Truong Dang,
• Thao Thu Thi Huynh,
• Guo-Ping Chang-Chien and
• Ha Manh Bui

Beilstein J. Nanotechnol. 2025, 16, 1401–1416, doi:10.3762/bjnano.16.102

• removal in water and its ability to restore functionality in microplastic-contaminated soils. Biochar applications in restoring MP-contaminated soil Improving plant growth under MP stress MPs negatively impact crop performance by reducing biomass production, inhibiting stem and root development and

• example, 1% corn stalk biochar-based microbial consortia (e.g., Bacillus B28) applied to soil containing 10% rubber crumb significantly increased peanut production by 58.86% and yield by 81.41% [52]. Principal component analysis (PCA) in Figure 5b reveals a strong correlation between biomass performance

• and biochar concentration, underscoring biochar’s pivotal role in soil remediation and plant performance enhancement in MP-contaminated soils. Enhancement of soil physicochemical properties MPs exert significant impacts on soil physicochemical properties, altering its physical structure, chemical

Parylene-coated platinum nanowire electrodes for biomolecular sensing applications

• Chao Liu,
• Peker Milas,
• Michael G. Spencer and
• Birol Ozturk

Beilstein J. Nanotechnol. 2025, 16, 1392–1400, doi:10.3762/bjnano.16.101

• portable and reliable devices [6]. Contemporary nanoscale biosensors are engineered for diverse applications, employing a variety of materials and design architectures to optimize performance and functionality. For example, carbon nanotubes (CNTs) are categorized as either single-walled or multiwalled

• stability of metal nanoparticles limits their application in biological systems and decreases their performance [12]. Other materials like silicon quantum dots, ion-imprinted polymer, and hydrogels have unique biocompatibility and specificity advantages, but long-term stability and cost make them

• 0.3–10 mM (Figure 4c), and the LoD is 0.01 mM glucose (Figure 4d). With limited surface area, LoD and detection range of our nanowire electrodes are inherently constrained. However, surface modification has been shown to enhance electrode performance, as described in the Introduction section

Synthesis and antibacterial properties of nanosilver-modified cellulose triacetate membranes for seawater desalination

• Lei Wang,
• Shizhe Li,
• Kexin Xu,
• Wenjun Li,
• Ying Li and
• Gang Liu

Beilstein J. Nanotechnol. 2025, 16, 1380–1391, doi:10.3762/bjnano.16.100

• , indicating the potential for repeated use and long-term application [21]. Zhao and Park’s group incorporated in situ synthesized silver-loaded graphene oxide (GO-Ag) nanoparticles into polyvinyl alcohol/chitosan (PVA/CS) electrospun nanofiber membranes to boost desalination performance. The PVA/CS/GO-Ag

• membranes exhibited outstanding antibacterial performance against Escherichia coli and Staphylococcus aureus [22]. Mayyahi introduced TiO2 nanoparticles into the polyamide layer of traditional TFC membranes by interfacial polymerization with m-phenylenediamine to create a thin film nanocomposite (TFN

• for antibacterial purposes are diverse and include metallic silver, silver salts, and composites of Ag with other materials. The integration of nanotechnology with Ag, particularly when incorporated into polymer membranes, has demonstrated significant potential for enhancing membrane performance. CTA

Enhancing the therapeutical potential of metalloantibiotics using nano-based delivery systems

• Alejandro Llamedo,
• Marina Cano,
• Raquel G. Soengas and
• Francisco J. García-Alonso

Beilstein J. Nanotechnol. 2025, 16, 1350–1366, doi:10.3762/bjnano.16.98

• colleagues. Thus, the complex formed upon treatment of the flavonoid catechin (CAT, 17) (Figure 4) and a Zn(II) salt was encapsulated in β-CS-NPs, and the antibacterial performance against E. coli and L. innocua was subsequently investigated [123]. Nano-encapsulated systems exhibited low polydispersity and

• phospholipid conjugate 21 (Figure 5) in liposomes have been explored as an strategy to enhance antimicrobial performance while preserving host cell compatibility [141]. Liposomal formulations incorporating the Ir complex displayed superior photophysical properties compared to the free metallodrug, notably

Ferroptosis induction by engineered liposomes for enhanced tumor therapy

• Alireza Ghasempour,
• Mohammad Amin Tokallou,
• Mohammad Reza Naderi Allaf,
• Mohsen Moradi,
• Hamideh Dehghan,
• Mahsa Sedighi,
• Mohammad-Ali Shahbazi and
• Fahimeh Lavi Arab

Beilstein J. Nanotechnol. 2025, 16, 1325–1349, doi:10.3762/bjnano.16.97

• ][120]. 3.2 Characterization of liposomes Characterization of liposomes is important to ensure their quality and performance as drug delivery systems. Several techniques are commonly used to analyze the properties of liposomes, including size, lamellarity, surface charge, and EE [110][121]. Dynamic

• systems. The EE of liposomes, which determines the amount of drug loaded into the vesicles, can be evaluated by various analytical methods. High-performance liquid chromatography (HPLC) and capillary electrophoresis (CE) are widely used methods to quantify the encapsulated drug [110][125]. HPLC separates

Deep-learning recognition and tracking of individual nanotubes in low-contrast microscopy videos

• Vladimir Pimonov,
• Said Tahir and
• Vincent Jourdain

Beilstein J. Nanotechnol. 2025, 16, 1316–1324, doi:10.3762/bjnano.16.96

• the number of data points shown in Figure 4 arises from the exclusion of videos manually analyzed during model training from the AI-based analysis, in order to avoid bias and ensure an independent performance assessment. The AI-extracted data in Figure 4 represents a small fraction of all data

• the performance comparable to the current state-of-the-art models [28]. Expanding the dataset to include more diverse video quality and nanotube localization can lead to more stable models [29]. Moreover, replacing computationally demanding models like Mask-RCNN with smaller models could enhance

• overall performance, although potentially reducing recognition accuracy. Automating recognition and tracking is essential for high-throughput video analysis, which is critical for understanding and modeling complex nanoscale phenomena. The differential video treatment approach, combined with the deep

Enhancing the photoelectrochemical performance of BiOI-derived BiVO₄ films by controlled-intensity current electrodeposition

• Huu Phuc Dang,
• Khanh Quang Nguyen,
• Nguyen Thi Mai Tho and
• Tran Le

Beilstein J. Nanotechnol. 2025, 16, 1289–1301, doi:10.3762/bjnano.16.94

• Abstract This study investigates the fabrication of BiVO4 photoanodes using a controlled-intensity current electrodeposition method to improve their photoelectrochemical (PEC) performance. The impact of varying the deposition current density and VO(acac)2 concentration was systematically analyzed to

• charge carriers, which severely restrict its PEC performance [10][11][12]. Various strategies have been explored to overcome these challenges and optimize the structural, electronic, and surface properties of BiVO4 [13][14]. Hydrothermal synthesis has been used to produce highly crystalline BiVO4 films

• produce BiVO4 thin films at high deposition rates; however, this method resulted in irregular grain structures and significant material defects, limiting the PEC performance improvements. Electrodeposition has emerged as a promising low-cost and scalable technique for BiVO4 film fabrication, offering

Better together: biomimetic nanomedicines for high performance tumor therapy

• Imran Shair Mohammad,
• Gizem Kursunluoglu,
• Anup Kumar Patel,
• Hafiz Muhammad Ishaq,
• Cansu Umran Tunc,
• Dilek Kanarya,
• Mubashar Rehman,
• Omer Aydin and
• Yin Lifang

Beilstein J. Nanotechnol. 2025, 16, 1246–1276, doi:10.3762/bjnano.16.92

• and MHT performance in vitro. Furthermore, RAW267.4-loaded with Fe@Fe3O4-DHCA demonstrated efficiency in vivo. Thus, Fe@Fe3O4-DHCA nanoparticles showed great application potential for tumor diagnosis and therapy [34]. 1.1.3 Neutrophils. Neutrophils are among the most abundant and frontline phagocytes

Functional bio-packaging enhanced with nanocellulose from rice straw and cinnamon essential oil Pickering emulsion for fruit preservation

• Tuyen B. Ly,
• Duong D. T. Nguyen,
• Hieu D. Nguyen,
• Yen T. H. Nguyen,
• Bup T. A. Bui,
• Kien A. Le and
• Phung K. Le

Beilstein J. Nanotechnol. 2025, 16, 1234–1245, doi:10.3762/bjnano.16.91

• dispersibility of essential oils in biopolymer matrices but also enhances the overall compatibility and performance of the biopackaging material [22]. Our previous research has demonstrated that nanocellulose can effectively encapsulate CEO into a PE with small particle sizes (<700 nm), high stability, and

• radicals [47]. The antioxidative performance of the films aligns with previous studies on essential oil-infused biopolymer matrices, confirming their potential to enhance food packaging stability by preventing oxidative degradation [48]. With increasing CEO concentration, transmittance decreased

Hydrogels and nanogels: effectiveness in dermal applications

• Jéssica da Cruz Ludwig,
• Diana Fortkamp Grigoletto,
• Daniele Fernanda Renzi,
• Wolf-Rainer Abraham,
• Daniel de Paula and
• Najeh Maissar Khalil

Beilstein J. Nanotechnol. 2025, 16, 1216–1233, doi:10.3762/bjnano.16.90

• of methodologies designed to obtain them. In addition to optimizing the physicochemical methods used to prepare nanogels and hydrogels, the application of precision engineering principles has proven essential to enhance the therapeutic performance of these formulations [63][64]. In developing

Investigation of the solubility of protoporphyrin IX in aqueous and hydroalcoholic solvent systems

• Michelly de Sá Matsuoka,
• Giovanna Carla Cadini Ruiz,
• Marcos Luciano Bruschi and
• Jéssica Bassi da Silva

Beilstein J. Nanotechnol. 2025, 16, 1209–1215, doi:10.3762/bjnano.16.89

• observed in these samples, whereas samples shown in Figure 1C and Figure 1D appear clear. The sample displayed in Figure 1D was the most soluble and transparent, demonstrating the improved system performance in the presence of P407. Although Franco [5] reported high solubility of PpIX in aqueous systems

Chitosan nanocomposite containing rotenoids: an alternative bioinsecticidal approach for the management of Aedes aegypti

• Maria A. A. Bertonceli,
• Vitor D. C. Cristo,
• Ivo J. Vieira,
• Francisco J. A. Lemos,
• Arnoldo R. Façanha,
• Raimundo Braz-Filho,
• Gustavo V. T. Batista,
• Luis G. M. Basso,
• Sérgio H. Seabra,
• Thalya S. R. Nogueira,
• Felipe F. Moreira,
• Arícia L. E. M. Assis,
• Antônia E. A. Oliveira and
• Kátia V. S. Fernandes

Beilstein J. Nanotechnol. 2025, 16, 1197–1208, doi:10.3762/bjnano.16.88

• encapsulation efficiency is estimated to be ≥99% within the detection limits of high-performance liquid chromatography (HPLC) and thin-layer chromatography (TLC) methods applied, indicating a highly effective incorporation of the rotenoids into the nanochitosan matrix. In addition to the high encapsulation

• of 1 cm−1 and an accumulation of 35 scans per spectrum. A compressive force of 15 N was applied to the samples during measurement to ensure proper contact with the ATR crystal surface. Quantification of rotenoids by high-performance liquid chromatography The quantification of rotenoids was performed

Electronic and optical properties of chloropicrin adsorbed ZnS nanotubes: first principle analysis

• Prakash Yadav,
• Boddepalli SanthiBhushan and
• Anurag Srivastava

Beilstein J. Nanotechnol. 2025, 16, 1184–1196, doi:10.3762/bjnano.16.87

• composites with other materials, such as carbon nanotubes, to optimize performance [26]. Furthermore, the flexible synthesis of ZnS NTs with controlled morphology and size allows for tailoring their sensing capabilities. External stimuli combined with machine learning can further enhance their sensitivity

• humidity sensing performance compared to that of ZnO/ZnS nanorod arrays and ZnO nanorod arrays, with enhanced response, faster recovery, good linearity, and reliable reproducibility across a wide range of relative humidity conditions at room temperature. Giri et al. [48] demonstrated that phase-selective

• ZnO@ZnS heterostructures and ZnS NTs exhibited superior amperometric cholesterol sensing performance, with ZnS NTs achieving the highest sensitivity (598 mA/m2) and low detection limits among the configurations studied. Despite these advances, the use of ZnS NT for detecting chloropicrin (CP), a

Crystalline and amorphous structure selectivity of ignoble high-entropy alloy nanoparticles during laser ablation in organic liquids is set by pulse duration

• Robert Stuckert,
• Felix Pohl,
• Oleg Prymak,
• Ulrich Schürmann,
• Christoph Rehbock,
• Lorenz Kienle and
• Stephan Barcikowski

Beilstein J. Nanotechnol. 2025, 16, 1141–1159, doi:10.3762/bjnano.16.84

• to be the catalytically active species [108] while in HEA NP electrocatalysis, such oxides are formed under anodic potential [19]. Also, the presence of surface manganese oxide still provides good catalytic activity with sharp performance profiles allowing for derivation of composition–activity

Deep learning for enhancement of low-resolution and noisy scanning probe microscopy images

• Samuel Gelman,
• Irit Rosenhek-Goldian,
• Nir Kampf,
• Marek Patočka,
• Maricarmen Rios,
• Marcos Penedo,
• Georg Fantner,
• Amir Beker,
• Sidney R. Cohen and
• Ido Azuri

Beilstein J. Nanotechnol. 2025, 16, 1129–1140, doi:10.3762/bjnano.16.83

• the generated image. For this reason, it is always important to combine metrics from both domains, to first assess the fidelity of the reconstructed image with respect to a reference image and then its quality when attempting to quantify the performance of the upscaling methods and models. An

• models and quantified their validity and performance by fidelity and quality metrics that were further supported by a survey taken by AFM experts. We found that, overall, the pre-trained SR deep learning models accurately retain the information from the low-resolution images when compared to the GT while

• compared to the GT. There was no statistically significant difference between the performance of deep learning models compared to the traditional methods, as shown by the p-value Tukey’s range test matrix comparisons in Figure 3 (all p-values are bigger than 0.98, except for that of the bilinear method

Single-layer graphene oxide film grown on α-Al₂O₃(0001) for use as an adsorbent

• Shiro Entani,
• Mitsunori Honda,
• Masaru Takizawa and
• Makoto Kohda

Beilstein J. Nanotechnol. 2025, 16, 1082–1087, doi:10.3762/bjnano.16.79

• of radioactive Cs contaminants from rocks and soils [21]. The resulting solution is a substantial quantity of low-level radioactive treated water. Therefore, the adsorbent needs to possesses high-adsorption performance, a rapid reaction rate, and cost-effectiveness in production. Romanchuk et al

Piezoelectricity of hexagonal boron nitrides improves bone tissue generation as tested on osteoblasts

• Sevin Adiguzel,
• Nilay Cicek,
• Zehra Cobandede,
• Feray B. Misirlioglu,
• Hulya Yilmaz and
• Mustafa Culha

Beilstein J. Nanotechnol. 2025, 16, 1068–1081, doi:10.3762/bjnano.16.78

• for cellular processes that are essential for bone repair and regeneration, which could explain the superior performance of hBNs in promoting osteoblast migration compared to that of BaTiO3 under US exposure. This suggests that the combination of hBNs and US may provide a more favorable environment

Soft materials nanoarchitectonics: liquid crystals, polymers, gels, biomaterials, and others

• Katsuhiko Ariga

Beilstein J. Nanotechnol. 2025, 16, 1025–1067, doi:10.3762/bjnano.16.77

• heterocoronene discotic liquid phase molecules can also serve as an excellent case study for intermolecular interactions in bulky molecular systems. Based on molecular nanoarchitectonics, this will facilitate the establishment of design rules for optimal performance in device applications. Extended π-conjugated

• output performance of the bulk photovoltaic effect. Observations were made in liquid crystal cells containing both compounds, revealing that the compounds within the chiral ordered smectic phase, in a polarized state, demonstrated the ferroelectric bulk photovoltaic effect, which resulted in a

• photocurrent with no applied bias. The reported outcomes can be beneficial for enhancing the performance of the ferroelectric bulk photovoltaic effect in organic ferroelectric π-conjugated compounds, thereby potentially accelerating the creation of next-generation organic thin-film sensors and photovoltaics

Multifunctional properties of bio-poly(butylene succinate) reinforced with multiwalled carbon nanotubes

• Volodymyr Krasinskyi,
• Krzysztof Bajer,
• Ludmila Dulebova,
• Nickolas Polychronopoulos,
• Oksana Krasinska and
• Daniel Kaczor

Beilstein J. Nanotechnol. 2025, 16, 1014–1024, doi:10.3762/bjnano.16.76

• of MWCNTs to tailor the properties of BioPBS for specific applications, such as in the packaging, automotive, and biomedical industries, where both biodegradability and enhanced material performance are desirable. Keywords: melt compounding; multiwalled carbon nanotubes; poly(butylene succinate

• strength, thermal stability, and biodegradability. However, to broaden its range of applications, certain properties require enhancement, including mechanical performance, thermal and electrical conductivity, biodegradation rate, and barrier properties [1][2][3][4][5]. The limited biodegradability of PBS

• performance with processability and cost-effectiveness. Increasing the CNT concentration beyond this level resulted in a marked rise in melt viscosity and the formation of agglomerates within the polymer matrix, which adversely affected both the processing behavior and the final properties of the composite

Shape, membrane morphology, and morphodynamic response of metabolically active human mitochondria revealed by scanning ion conductance microscopy

• Eric Lieberwirth,
• Anja Schaeper,
• Regina Lange,
• Ingo Barke,
• Simone Baltrusch and
• Sylvia Speller

Beilstein J. Nanotechnol. 2025, 16, 951–967, doi:10.3762/bjnano.16.73

• ), regardless of the isolation method. After storing the mitochondrial fractions at −80 °C for four days to three months, oxygen consumption was only slightly reduced to 182.8 ± 16.88 μmol·L−1 per 10 min. Thus, freezing and thawing have little effect on mitochondrial performance. Because the additives are not

• their metabolic performance. These fast adaptive behaviours are referred to as morphodynamic effects, or morphodynamics for short [6]. In the context of SICM, morphodynamic changes in mitochondrial shape can be directly observed. Because of the comparatively long measurement time in relation to other

Synthesis of biowaste-derived carbon-dot-mediated silver nanoparticles and the evaluation of electrochemical properties for supercapacitor electrodes

• Navya Kumari Tenkayala,
• Chandan Kumar Maity,
• Md Moniruzzaman and
• Subramani Devaraju

Beilstein J. Nanotechnol. 2025, 16, 933–943, doi:10.3762/bjnano.16.71

• ]. Lokhande et al. reached a specific capacitance (SC) of 424 F/g for the Kimchi cabbage extract mediated AgNPs [16]. The enhanced performance was credited to the fact that the AgNPs were smaller, which meant that there was a bigger surface area for operative conducting pathways. Nevertheless, chemical

• water stability. The combination of EDLC-type CDs with pseudocapacitive AgNPs affords superior capacitive performance and stability, which are important for supercapacitor electrodes. The overall methodology along with the optical and electrochemical charge-storing performance have been schematically

• -storing EDLC-type mechanism. Given the low charge density of K+ ions, which facilitates its access to the electrode during the electrochemical reaction, it may be concluded that this occurrence may have an impact on the performance of the electrochemical reaction. The deintercalation and intercalation of

Structural and magnetic properties of microwave-synthesized reduced graphene oxide/VO₂/Fe₂O₃ nanocomposite

• Sumanta Sahoo,
• Ankur Sood and
• Sung Soo Han

Beilstein J. Nanotechnol. 2025, 16, 921–932, doi:10.3762/bjnano.16.70

• NC displayed good electrochemical performance as the SC electrode [13]. In another work, Kumar et al. reported the MW-assisted synthesis of Fe3O4/rGO NC using FeCl3 aqueous salt as the precursor [14]. Ferrocene, an Fe-based organometallic compound, was also utilized as the precursor for developing