Serum heat inactivation diminishes ApoE-mediated uptake of D-Lin-MC3-DMA lipid nanoparticles

• Demian van Straten,
• Luuk van de Schepop,
• Rowan Frunt,
• Pieter Vader and
• Raymond M. Schiffelers

Beilstein J. Nanotechnol. 2025, 16, 740–748, doi:10.3762/bjnano.16.57

• delivery efficiency, it is becoming increasingly clear that the in vivo environment to which the nanoparticles will be exposed should be considered during LNP development. Nevertheless, the initial screening of nanoparticles in vitro is often restricted to experiments using tissue culture media

Synthesis of a multicomponent cellulose-based adsorbent for tetracycline removal from aquaculture water

• Uyen Bao Tran,
• Ngoc Thanh Vo-Tran,
• Khai The Truong,
• Dat Anh Nguyen,
• Quang Nhat Tran,
• Huu-Quang Nguyen,
• Jaebeom Lee and
• Hai Son Truong-Lam

Beilstein J. Nanotechnol. 2025, 16, 728–739, doi:10.3762/bjnano.16.56

• involves van der Waals forces, which primarily represent electrostatic interactions. Notably, TC is an aromatic organic compound with an amino group that can accept protons (H+) from the environment, acquiring a positive charge. The CMC network within PGC includes oxygen-containing functional groups (‒OH

Polyurethane/silk fibroin-based electrospun membranes for wound healing and skin substitute applications

• Iqra Zainab,
• Zohra Naseem,
• Syeda Rubab Batool,
• Muhammad Waqas,
• Ahsan Nazir and
• Muhammad Anwaar Nazeer

Beilstein J. Nanotechnol. 2025, 16, 591–612, doi:10.3762/bjnano.16.46

• reduce inflammation, control infection, maintain a moist environment, promote cell growth, deliver bioactive molecules, and reduce scar formation throughout the wound healing process as shown in Figure 2B [72]. Although various materials can be used as effective dermal substitutes, this study focuses on

• mechanical capabilities, while improving blood clotting as demonstrated by reduced whole blood coagulation time. This study also indicated a sustained release of CHD over 8 h, with a faster drug release rate in an acidic environment. These properties highlight the dressing’s potential for effective

Feasibility analysis of carbon nanofiber synthesis and morphology control using a LPG premixed flame

• Iftikhar Rahman Bishal,
• Muhammad Hilmi Ibrahim,
• Norikhwan Hamzah,
• Mohd Zamri Mohd Yusop,
• Faizuan Bin Abdullah,
• I Putu Tedy Indrayana and
• Mohd Fairus Mohd Yasin

Beilstein J. Nanotechnol. 2025, 16, 581–590, doi:10.3762/bjnano.16.45

• equivalence ratio of 1.80. As expected, there is large number of CNFs present in the sample, as shown in Figure 8. The fraction of amorphous carbon in this sample is much smaller than that in Figure 7. The flame at 1.80 equivalence ratio ensures a suitable environment for carbon deposition. At higher fuel

• higher-temperature environment, which accelerates the breakdown of hydrocarbon molecules into free carbon atoms. The carbon atoms, in the absence of efficient catalytic activity, aggregate to form amorphous carbon rather than ordered structures such as CNFs as shown in Figure 7a. In contrast, at an

• equivalence ratio of 1.80, despite a higher carbon supply rate, the lower temperature does not sufficiently drive the decomposition reaction, thus providing a more conducive environment for the growth of ordered carbon structures as shown in Figure 8a [30]. The Raman spectra in Figure 9 show the ID and IG

Nanomaterials in targeting amyloid-β oligomers: current advances and future directions for Alzheimer's disease diagnosis and therapy

• Shiwani Randhawa,
• Trilok Chand Saini,
• Manik Bathla,
• Rahul Bhardwaj,
• Rubina Dhiman and
• Amitabha Acharya

Beilstein J. Nanotechnol. 2025, 16, 561–580, doi:10.3762/bjnano.16.44

• specificity allow for efficient capture even at low concentrations, crucial in the complex biological environment of the brain. Recent advancements in immunoassay technology have led to the development of ultrasensitive methods for detecting Aβ-derived diffusible ligands (ADDLs) and AβOs. A novel immunoassay

Water in nanoporous hexagonal boron nitride nanosheets: a first-principles study

• Juliana A. Gonçalves,
• Ronaldo J. C. Batista and
• Marcia C. Barbosa

Beilstein J. Nanotechnol. 2025, 16, 510–519, doi:10.3762/bjnano.16.39

• environment) or μN (i.e., a N-rich environment). To determine the chemical potential of nitrogen in N-rich environments, we utilize either the N2 molecule (whereby and μB = μBN − μN) or the NH3 molecule (in this case, and μB = μBN − μN). In boron-rich environments, the BH3 molecule is employed to determine

• values, the transition from a B-rich to a N-rich environment has a small effect on the formation energy of the two most stable porous h-BN structures. These structures remain significantly more energetically stable than the other triangular porous h-BN monolayers. The adsorption energy, Eads, was

• typically observed at lower temperatures. The incorporation of B–H or B–OH moieties at the vertices of triangular pores results in a significant reduction in formation energies. The decrease in energy per atom ranges from −1.230 to −0.525 eV, depending on the chemical environment (B-rich or N-rich, defined

N₂⁺-implantation-induced tailoring of structural, morphological, optical, and electrical characteristics of sputtered molybdenum thin films

• Usha Rani,
• Kafi Devi,
• Divya Gupta and
• Sanjeev Aggarwal

Beilstein J. Nanotechnol. 2025, 16, 495–509, doi:10.3762/bjnano.16.38

• for various applications in photovoltaics, sensors, optoelectronics, and electronic devices. In the present work, Mo thin films with varying thickness of 150, 200, 250, and 300 nm were deposited on Si(100) substrates using radio frequency (RF) sputtering in an argon environment at ambient temperature

Performance optimization of a microwave-coupled plasma-based ultralow-energy ECR ion source for silicon nanostructuring

• Joy Mukherjee,
• Safiul Alam Mollick,
• Tanmoy Basu and
• Tapobrata Som

Beilstein J. Nanotechnol. 2025, 16, 484–494, doi:10.3762/bjnano.16.37

• exploring optimal parameters to achieve stable and intense beam currents. The cost-effectiveness and versatility of this ion source make it particularly noteworthy, offering a practical solution for generating reasonable beam currents. The ion source operates within an ultrahigh-vacuum environment

Effect of additives on the synthesis efficiency of nanoparticles by laser-induced reduction

• Rikuto Kuroda,
• Takahiro Nakamura,
• Hideki Ina and
• Shuhei Shibata

Beilstein J. Nanotechnol. 2025, 16, 464–472, doi:10.3762/bjnano.16.35

• practical use. In this study, we attempted to improve the synthesis efficiency of nanoparticles using LRL by controlling the reaction environment of the solution during laser irradiation. Results and Discussion Increasing the synthesis efficiency of nanoparticles via laser-induced reduction by adding

Synthetic-polymer-assisted antisense oligonucleotide delivery: targeted approaches for precision disease treatment

• Ana Cubillo Alvarez,
• Dylan Maguire and
• Ruairí P. Brannigan

Beilstein J. Nanotechnol. 2025, 16, 435–463, doi:10.3762/bjnano.16.34

• stability in the bloodstream and enabled the controlled release of MALAT1 ASO in the brain’s reductive environment. As a result, significant knockdown of targeted long non-coding RNA was observed in key brain regions, including the cerebral cortex and hippocampus, after a single intravenous administration

Quantification of lead through rod-shaped silver-doped zinc oxide nanoparticles using an electrochemical approach

• Ravinder Lamba,
• Gaurav Bhanjana,
• Neeraj Dilbaghi,
• Vivek Gupta and
• Sandeep Kumar

Beilstein J. Nanotechnol. 2025, 16, 422–434, doi:10.3762/bjnano.16.33

• ; Introduction According to the literature, a lot of work has been done to create durable and dependable smart sensors for the effective identification of analytes that are harmful but also crucial for the environment and technology [1]. Even at very low levels, heavy metals can permanently harm health, and

• their acute exposure leads to chronic disorders by affecting organ functions [2]. For example, lead poisoning in liquid effluents, is one of the worst environmental hazards which can affect human health and readily impact immune responses [3]. Due to the detrimental effects on the environment and human

Biomimetics and bioinspired surfaces: from nature to theory and applications

• Rhainer Guillermo Ferreira,
• Thies H. Büscher,
• Manuela Rebora,
• Poramate Manoonpong,
• Zhendong Dai and
• Stanislav N. Gorb

Beilstein J. Nanotechnol. 2025, 16, 418–421, doi:10.3762/bjnano.16.32

• environmental pressures. Such pressures involve intricate interactions between surface structures and the environment across different scales, including nano-, micro-, and macroscales. Biomimetics aims at making use of understanding how these adaptations and the particular material properties of these surfaces

Size control of nanoparticles synthesized by pulsed laser ablation in liquids using donut-shaped beams

• Abdel Rahman Altakroury,
• Oleksandr Gatsa,
• Farbod Riahi,
• Zongwen Fu,
• Miroslava Flimelová,
• Andrei Samokhvalov,
• Stephan Barcikowski,
• Carlos Doñate-Buendía,
• Alexander V. Bulgakov and
• Bilal Gökce

Beilstein J. Nanotechnol. 2025, 16, 407–417, doi:10.3762/bjnano.16.31

• different. The maximum size (and thereby the lifetime) of the bubble was significantly reduced for the donut-shaped beam compared to the tight focus, which was attributed to the altered bubble shape. The donut beam shape appears to influence the bubble dynamics, potentially creating a different environment

Engineered PEG–PCL nanoparticles enable sensitive and selective detection of sodium dodecyl sulfate: a qualitative and quantitative analysis

• Soni Prajapati and
• Ranjana Singh

Beilstein J. Nanotechnol. 2025, 16, 385–396, doi:10.3762/bjnano.16.29

• Soni Prajapati Ranjana Singh Department of Biochemistry, King George’s Medical University, Lucknow, India 10.3762/bjnano.16.29 Abstract Sodium dodecyl sulfate (SDS) is a widely used anionic surfactant in laboratory, household, and industrial applications, which ultimately enters the environment

• reagent). This interaction disrupts the local environment around the dye molecules, changing the optical properties of the PEG–PCL NPs–Bradford reagent complex. The ionic interactions cause the G-250 dye (from the Bradford reagent), which originally exhibits a brownish color, to change into a blue color

Development of a mucoadhesive drug delivery system and its interaction with gastric cells

• Ahmet Baki Sahin,
• Serdar Karakurt and
• Deniz Sezlev Bilecen

Beilstein J. Nanotechnol. 2025, 16, 371–384, doi:10.3762/bjnano.16.28

• site. In situ mucoadhesion studies The ability of nanoparticles to stick to mucus, known as mucoadhesion, is important for retention at mucus-bearing sites and, thus, prolonged drug release into the environment [52]. The mucus interaction of the EudAlg NPs was first studied by DLS measurements, where

Tailoring of physical properties of RF-sputtered ZnTe films: role of substrate temperature

• Kafi Devi,
• Usha Rani,
• Arun Kumar,
• Divya Gupta and
• Sanjeev Aggarwal

Beilstein J. Nanotechnol. 2025, 16, 333–348, doi:10.3762/bjnano.16.25

• sample. The peaks observed in the emission spectra are accredited to deep and shallow band transitions. The variation in the width of emission peaks may be due to the change in the lattice environment with substrate temperature. The photoluminescence intensity depends on the number of charge carriers

Graphene oxide–chloroquine conjugate induces DNA damage in A549 lung cancer cells through autophagy modulation

• Braham Dutt Arya,
• Sandeep Mittal,
• Prachi Joshi,
• Alok Kumar Pandey,
• Jaime E. Ramirez-Vick,
• Govind Gupta and
• Surinder P. Singh

Beilstein J. Nanotechnol. 2025, 16, 316–332, doi:10.3762/bjnano.16.24

• /IG ratio (0.882) is observed for the GO–Chl sample compared to that of GO (0.929). This indicates a possible conversion of the sp3 carbon to sp2 carbon due to the reducing environment imparted by the amino functionalities present on the Chl, which was also corroborated by FTIR data [47]. Furthermore

Enhancing mechanical properties of chitosan/PVA electrospun nanofibers: a comprehensive review

• Nur Areisman Mohd Salleh,
• Amalina Muhammad Afifi,
• Fathiah Mohamed Zuki and
• Hanna Sofia SalehHudin

Beilstein J. Nanotechnol. 2025, 16, 286–307, doi:10.3762/bjnano.16.22

• , and environment. For electrospinning, factors such as applied electric field, distance between the needle and collector, flow rate, and needle diameter affect the fabrication of the nanofibrous sample. Solution parameters include the types of solvent, polymer concentration, viscosity, and solution

• environment because it mitigates the long-term effects of PVA waste on ecosystems. Research on PVA biodegradation further supports its status as an environmentally friendly polymer [65]. The mechanical properties of PVA depend on several factors, such as molecular weight and retained moisture [66]. Dry, fully

• properties [170][171]. This technology is advantageous in terms of energy consumption, processing time, and solvent use, and it is also non-hazardous to the environment [161]. In a study on the surface modification of electrospun chitosan/PVA nanofibers, PVA was dissolved in distilled water and mixed with

Emerging strategies in the sustainable removal of antibiotics using semiconductor-based photocatalysts

• Yunus Ahmed,
• Keya Rani Dutta,
• Parul Akhtar,
• Md. Arif Hossen,
• Md. Jahangir Alam,
• Obaid A. Alharbi,
• Hamad AlMohamadi and
• Abdul Wahab Mohammad

Beilstein J. Nanotechnol. 2025, 16, 264–285, doi:10.3762/bjnano.16.21

• , Chittagong University of Engineering and Technology, Chattogram-4349, Bangladesh Department of Civil Engineering, Chittagong University of Engineering and Technology, Chattogram-4349, Bangladesh Water Management & Treatment Technologies Institute, Sustainability & Environment Sector, King Abdulaziz City for

• antibiotics has raised public concern, especially because they are environmental contaminants originating from human and animal waste [5]. These antibiotics can persist without change or as active metabolites in the environment, posing significant toxicity risks to aquatic and human life [6][7][8]. The

• mechanisms of how these materials or processes degrade antibiotics. They do not address the entry of antibiotics into the environment, their adverse impact on human health and the environment, or the effects of each treatment process in relation to established industrial applications. As a result, there is a

Radiosensitizing properties of dual-functionalized carbon nanostructures loaded with temozolomide

• Radmila Milenkovska,
• Nikola Geskovski,
• Dushko Shalabalija,
• Ljubica Mihailova,
• Petre Makreski,
• Dushko Lukarski,
• Igor Stojkovski,
• Maja Simonoska Crcarevska and
• Kristina Mladenovska

Beilstein J. Nanotechnol. 2025, 16, 229–251, doi:10.3762/bjnano.16.18

• effect of PEG on cell growth and its biocompatibility by inducing metabolism modulations and survival autophagy through creating an intracellular hypoxic environment. Although there is no consensus on whether the role of folate in cancer cells is protective or harmful, a cytotoxic effect was also

Synthesis and the impact of hydroxyapatite nanoparticles on the viability and activity of rhizobacteria

• Bedah Rupaedah,
• Indrika Novella,
• Atiek Rostika Noviyanti,
• Diana Rakhmawaty Eddy,
• Anna Safarrida,
• Abdul Hapid,
• Zhafira Amila Haqqa,
• Suryana Suryana,
• Irwan Kurnia and
• Fathiyah Inayatirrahmi

Beilstein J. Nanotechnol. 2025, 16, 216–228, doi:10.3762/bjnano.16.17

• to the nHA carrier material is not fully understood. However, the structure of nHA, characterized by its voids and crevices, provides an environment conducive to the growth and survival of rhizobacteria, a phenomenon known as biological fixation [33]. Figure 6, along with Table 3 and Table 4, shows

Recent advances in photothermal nanomaterials for ophthalmic applications

• Jiayuan Zhuang,
• Linhui Jia,
• Chenghao Li,
• Rui Yang,
• Jiapeng Wang,
• Wen-an Wang,
• Heng Zhou and
• Xiangxia Luo

Beilstein J. Nanotechnol. 2025, 16, 195–215, doi:10.3762/bjnano.16.16

• the dielectric environment present during their synthesis (see below in Figure 2b) [48][49]. Because of the direct occurrence of photothermal conversion on the surfaces of LSPR metals and its rapid nature, combined with the metals’ inherent high thermal conductivity and strong hydrophilicity, LSPR

• for clinical ILM staining, is better suited for generating VNBs on the ILM, and the high NIR absorbance of ICG is beneficial in the in vivo environment. Karen Peynshaert’s team [169] demonstrated that ICG can bind to the ILM and generate VNBs upon pulsed laser irradiation, thereby disrupting the

TiO₂ immobilized on 2D mordenite: effect of hydrolysis conditions on structural, textural, and optical characteristics of the nanocomposites

• Marina G. Shelyapina,
• Rosario Isidro Yocupicio-Gaxiola,
• Gleb A. Valkovsky and
• Vitalii Petranovskii

Beilstein J. Nanotechnol. 2025, 16, 128–140, doi:10.3762/bjnano.16.12

• nanoparticles of about 4 nm in size. It was found that the textural properties of the resulting materials are sensitive to the environment in which TEOT hydrolysis takes place. Alkoxides are, generally, not stable in protic solvents such as water. However, because of this property they are widely used as

Comparison of organic and inorganic hole transport layers in double perovskite material-based solar cell

• Deepika K and
• Arjun Singh

Beilstein J. Nanotechnol. 2025, 16, 119–127, doi:10.3762/bjnano.16.11

• , as well as geothermal, tidal, and solar energy. Renewable energy sources are unlimited and can be constantly replenished. In the coming years, renewable energy sources will contribute to decarbonizing energy systems. Solar energy safeguards both human health and a healthy environment [1]. Akmam and

Nanocarriers and macrophage interaction: from a potential hurdle to an alternative therapeutic strategy

• Naths Grazia Sukubo,
• Paolo Bigini and
• Annalisa Morelli

Beilstein J. Nanotechnol. 2025, 16, 97–118, doi:10.3762/bjnano.16.10

• standard treatment regimen for AIH. 6.2 Targeting lung diseases The immune system plays an essential role in the lungs, representing the largest surface exposed to the external environment. Pathogens can enter through the inhaled air via the epithelial layer or through the bloodstream via the endothelium