TEM sample preparation of lithographically patterned permalloy nanostructures on silicon nitride membranes

• Joshua Williams,
• Michael I. Faley,
• Joseph Vimal Vas,
• Peng-Han Lu and
• Rafal E. Dunin-Borkowski

Beilstein J. Nanotechnol. 2024, 15, 1–12, doi:10.3762/bjnano.15.1

• Abstract We have prepared ferromagnetic nanostructures intended for the investigation of high-frequency magnetization dynamics in permalloy (Py) nanodisks using Lorentz transmission electron microscopy (LTEM) and electron holography. Py nanodisks were fabricated on thin silicon nitride (SiN) membranes

• submicrometer apertures were milled on SiN membranes using a focused ion beam. Furthermore, we have developed a new TEM sample preparation method, where we fabricated Py nanostructures on a bulk substrate with a SiN buffer layer and etched the substrate to create a thin SiN membrane under the Py nanostructure

• information down to the nanometer/atomic scale. However, the corresponding samples need to be prepared on electron-beam-transparent membranes, which are very fragile and can easily break during standard lithography procedures. Although a lift-off approach has been demonstrated [20], alternative methods may be

Elasticity, an often-overseen parameter in the development of nanoscale drug delivery systems

• Agnes-Valencia Weiss and
• Marc Schneider

Beilstein J. Nanotechnol. 2023, 14, 1149–1156, doi:10.3762/bjnano.14.95

• barriers besides cellular membranes need to be addressed. A few examples of these barriers are penetration in or permeation through mucus, skin penetration, overcoming the blood brain barrier, or extravasation from blood vessels. Another challenge is the accumulation of particulate drug delivery systems in

Sulfur nanocomposites with insecticidal effect for the control of Bactericera cockerelli

• Lany S. Araujo-Yépez,
• Juan O. Tigrero-Salas,
• Vicente A. Delgado-Rodríguez,
• Vladimir A. Aguirre-Yela and
• Josué N. Villota-Méndez

Beilstein J. Nanotechnol. 2023, 14, 1106–1115, doi:10.3762/bjnano.14.91

• formulations, and reduce the amount of insecticide required for pest control [22]. Nanoparticles are known for their insecticidal properties; they interact with the cell membranes of the insects, causing the denaturation of organelles and enzymes, oxidative stress, and cell death [23][24]. Essential oils are

Spatial mapping of photovoltage and light-induced displacement of on-chip coupled piezo/photodiodes by Kelvin probe force microscopy under modulated illumination

• Zeinab Eftekhari,
• Nasim Rezaei,
• Hidde Stokkel,
• Jian-Yao Zheng,
• Andrea Cerreta,
• Ilka Hermes,
• Minh Nguyen,
• Guus Rijnders and
• Rebecca Saive

Beilstein J. Nanotechnol. 2023, 14, 1059–1067, doi:10.3762/bjnano.14.87

• spatially map voltage-induced oscillation of various sizes of piezoelectric membranes without the photodiode to investigate their position- and size-dependent displacement. Keywords: Kelvin probe force microscopy (KPFM); light-driven micro/nano systems; piezoelectric membrane; surface photovoltage (SPV

• each function of the components on the overall motion behavior. A variety of characterization techniques, such as white light interferometry, laser Doppler vibrometry (LDV), and double-beam laser interferometry (DBLI) have been used to determine the displacement of piezoelectric membranes [9][10

• previously been developed and reported by our group [32]. In further investigations, we used time-dependent AFM to determine the voltage-induced displacement of solely piezoelectric membranes without the photodiode. This experiment was performed to probe the local electromechanical properties of the

Green SPIONs as a novel highly selective treatment for leishmaniasis: an in vitro study against Leishmania amazonensis intracellular amastigotes

• Brunno R. F. Verçoza,
• Robson R. Bernardo,
• Luiz Augusto S. de Oliveira and
• Juliany C. F. Rodrigues

Beilstein J. Nanotechnol. 2023, 14, 893–903, doi:10.3762/bjnano.14.73

• different sizes. Furthermore, at high magnification, it is possible to observe that the SPIONS are frequently surrounded by membranes (Figure 3B, arrows). In addition, SPIONs were also observed inside the flagellar pocket (Figure 3C, arrowheads) and closely associated with the membrane. The uptake of SPIONs

Nanoarchitectonics for advanced applications in energy, environment and biology: Method for everything in materials science

• Katsuhiko Ariga

Beilstein J. Nanotechnol. 2023, 14, 738–740, doi:10.3762/bjnano.14.60

• also discuss coordination-assembled myricetin nanoarchitectonics [32], nanoarchitectonics for membranes with enhanced gas separation capabilities [33], nanoarchitectonics of the cathode of Li–O2 batteries [34], nanoarchitectonics in moist-electric generation [35], nanoarchitectonics for drug delivery

Suspension feeding in Copepoda (Crustacea) – a numerical model of setae acting in concert

• Alexander E. Filippov,
• Wencke Krings and
• Stanislav N. Gorb

Beilstein J. Nanotechnol. 2023, 14, 603–615, doi:10.3762/bjnano.14.50

• a basis to unravel the interplay between the feeding structures of suspension feeders, the preferred food, and the gathering performance. Additionally, it could open new avenues in the development of new filtration technologies (e.g., mucus-like filter media or bioinspired membranes) that use

On the use of Raman spectroscopy to characterize mass-produced graphene nanoplatelets

• Keith R. Paton,
• Konstantinos Despotelis,
• Naresh Kumar,
• Piers Turner and
• Andrew J. Pollard

Beilstein J. Nanotechnol. 2023, 14, 509–521, doi:10.3762/bjnano.14.42

• was then vacuum-filtered through alumina membranes (20 nm pore size), rinsed with IPA to remove residual NMP, and dried in a vacuum oven at 60 °C overnight. For samples 2 to 7, 3 mL of the dispersion was filtered, while for sample 1, ca. 30 mL was used to ensure adequate coverage of the membrane

Conjugated photothermal materials and structure design for solar steam generation

• Chia-Yang Lin and
• Tsuyoshi Michinobu

Beilstein J. Nanotechnol. 2023, 14, 454–466, doi:10.3762/bjnano.14.36

• on conjugated organic materials. Conjugated organic materials are processed into fibers, membranes, and porous structures. Therefore, nanostructure design based on the concept of nanoarchitectonics is crucial to achieve high SSG efficiency. We discuss the considerations for designing SSG absorbers

• ratio, high porosity, and high mass transport. Therefore, they are often applied to SSG absorbers along with other macrostructures such as membranes and foams [29][52][53][54][55]. One noticeable example is the study of nanofiber-based light-trapping coatings [29]. Ma et al. proposed an ultrasonic spray

• applied on top of the PS insulator without the need for an additional water transport layer. Membranes Janus structural membranes with hydrophilic and hydrophobic surfaces are key structures for highly efficient SSGs. Such Janus membranes can be easily produced by filtering or coating hydrophilic

Plasmonic nanotechnology for photothermal applications – an evaluation

• A. R. Indhu,
• L. Keerthana and
• Gnanaprakash Dharmalingam

Beilstein J. Nanotechnol. 2023, 14, 380–419, doi:10.3762/bjnano.14.33

The steep road to nonviral nanomedicines: Frequent challenges and culprits in designing nanoparticles for gene therapy

• Yao Yao,
• Yeongun Ko,
• Grant Grasman,
• Jeffery E. Raymond and
• Joerg Lahann

Beilstein J. Nanotechnol. 2023, 14, 351–361, doi:10.3762/bjnano.14.30

• should be closely monitored, as cell death can be misinterpreted as efficient inhibition, especially in metabolism-based assays. For these inhibitors that involve the permeablization of plasma membranes, such as filipin III, appropriate controls for plasma membrane integrity during the inhibition

Overview of mechanism and consequences of endothelial leakiness caused by metal and polymeric nanoparticles

• Magdalena Lasak and
• Karol Ciepluch

Beilstein J. Nanotechnol. 2023, 14, 329–338, doi:10.3762/bjnano.14.28

• NP interaction with cell membranes in order to eliminate the participation of transcellular transport was also investigated. In fact, TEM micrographs revealed a small number of 18 nm AuNPs undergoing endocytosis. However, subsequent studies with a cocktail of endocytosis inhibitors confirmed the

Recent progress in cancer cell membrane-based nanoparticles for biomedical applications

• Qixiong Lin,
• Yueyou Peng,
• Yanyan Wen,
• Xiaoqiong Li,
• Donglian Du,
• Weibin Dai,
• Wei Tian and
• Yanfeng Meng

Beilstein J. Nanotechnol. 2023, 14, 262–279, doi:10.3762/bjnano.14.24

• nanoparticles exhibit various effects (e.g., homotypic targeting, prolonging drug circulation, regulating the immune system, and penetrating biological barriers) after encapsulation by cancer cell membranes. The sensitivity and specificity of diagnostic methods will also be improved by utilizing the properties

• of cancer cell membranes. In this review, different properties and functions of cancer cell membranes are presented. Utilizing these advantages, nanoparticles can exhibit unique therapeutic capabilities in various types of diseases, such as solid tumors, hematological malignancies, immune system

• membranes, provides a new approach to address NP deficiencies [9]. The encapsulation of NPs with cell membranes can endow the NPs with biomimetic functions and replicate the biological characteristics derived from the original cells, such as the immune evasion of erythrocytes [10] and platelets [11] and the

Cyclodextrins as eminent constituents in nanoarchitectonics for drug delivery systems

• Makoto Komiyama

Beilstein J. Nanotechnol. 2023, 14, 218–232, doi:10.3762/bjnano.14.21

• applications. However, nucleic acids are intrinsically unstable in serum and do not readily cross the cellular plasma membranes. Accordingly, it is a big challenge to deliver them in the intact form into target cells. Conventional gene transfection reagents are not very good candidates, since multiple positive

• charges of high density can damage the membranes and organelles of normal cells. With the use of CyD-based DDSs, however, high transfection efficiency and low cytotoxicity have been accomplished with minimal immune stimulation. The preorganized three-dimensional molecular structure of CyD as well as the

• photocatalytic process destroy subcellular structures (e.g., cell membranes or organelle membranes). Various types of cancers are effectively treatable without significant side effects. However, most photosensitizers available at present are hydrophobic and easily aggregate in aqueous solution. Thus, the

A novel approach to pulsed laser deposition of platinum catalyst on carbon particles for use in polymer electrolyte membrane fuel cells

• Bogusław Budner,
• Wojciech Tokarz,
• Sławomir Dyjak,
• Andrzej Czerwiński,
• Bartosz Bartosewicz and
• Bartłomiej Jankiewicz

Beilstein J. Nanotechnol. 2023, 14, 190–204, doi:10.3762/bjnano.14.19

• electric power generation. Among various fuel cells, polymer electrolyte membrane fuel cells (PEMFCs) have received considerable attention because of several physicochemical advantages over other fuel cell types [1][2][3][4][5]. PEMFCs, constructed of polymer electrolyte membranes as the proton conductor

• cost of PEMFCs depend on the materials used to construct their major components, which are anode, cathode, and polymer electrolyte membranes [3][6]. Therefore, supplying good-performance materials with controlled nanostructures to fuel cell technology is a crucial issue [7]. One solution to this

• catalysts in a membrane electrode assembly (MEA) of PEMFCs fed with H2/air. The materials with Pt deposited on Vulcan XC-72R (samples A and B), like commercial catalysts, formed a good quality catalyst layer on the Nafion membranes. However, we encountered some issues during electrode preparation from the

Intermodal coupling spectroscopy of mechanical modes in microcantilevers

• Ioan Ignat,
• Bernhard Schuster,
• Jonas Hafner,
• MinHee Kwon,
• Daniel Platz and
• Ulrich Schmid

Beilstein J. Nanotechnol. 2023, 14, 123–132, doi:10.3762/bjnano.14.13

• coupling was proven in doubly clamped beams, square membranes and circular membranes [18][26][27][28][29][30][31]. For atomic force microscopy imaging, a slight angle between the sensing mechanical resonator and the sample of interest is required, ensuring that the only contact occurs between the sample

Frequency-dependent nanomechanical profiling for medical diagnosis

• Santiago D. Solares and
• Alexander X. Cartagena-Rivera

Beilstein J. Nanotechnol. 2022, 13, 1483–1489, doi:10.3762/bjnano.13.122

• optical imaging, the device could be equipped with one or more piezoelectrically excited membranes coupled with a sensing mechanism, such as an AFM cantilever or other type of mechanical sensor (similar stand-alone developments already exist [31][32]). The mechanical response of the membrane could be

Straight roads into nowhere – obvious and not-so-obvious biological models for ferrophobic surfaces

• Wilfried Konrad,
• Christoph Neinhuis and
• Anita Roth-Nebelsick

Beilstein J. Nanotechnol. 2022, 13, 1345–1360, doi:10.3762/bjnano.13.111

• segmentation of the water conduit network into compartments. Each pit pore connects two conduits, and this joint pore space is separated by a special nanoporous membrane, the pit membrane (Figure 4). When a conduit becomes dysfunctional due to embolism, the nanopores within the pit membranes prevent the

Roll-to-roll fabrication of superhydrophobic pads covered with nanofur for the efficient clean-up of oil spills

• Patrick Weiser,
• Robin Kietz,
• Marc Schneider,
• Matthias Worgull and
• Hendrik Hölscher

Beilstein J. Nanotechnol. 2022, 13, 1228–1239, doi:10.3762/bjnano.13.102

• , mixtures of oil (nonpolar) and water (polar) are easily separated. A promising application of nanofur is therefore the cleaning of oil spills [23][31]. This behavior can be also utilized for the fabrication of membranes that filter oil out of water (or vice versa) [17]. For that, the nanofur is perforated

Design of surface nanostructures for chirality sensing based on quartz crystal microbalance

• Yinglin Ma,
• Xiangyun Xiao and
• Qingmin Ji

Beilstein J. Nanotechnol. 2022, 13, 1201–1219, doi:10.3762/bjnano.13.100

• recognition of biomolecules (Figure 2) [38]. The sensing films of poly(EDOT-OH) with either R or S chirality were directly synthesized on the surface of the QCM electrode and engineered with different morphologies of nanotubular arrays and smooth membranes. The binding effects of fetal bovine serum, RGD

• -alanine was 307.97% more enantioselective than ᴅ-alanine. Similar enantioselectivity could also be achieved by Al/ʟ-Cys MLD films [123]. The methodology is also versatile and promising for the deposition of chiral thin films over any substrates or membranes of interest, which may promote the exploration

• oligomers, and the subsequent fibrillation process. The results give interesting insights into the crucial roles of biological membranes on protein amyloidosis, and how intrinsic chirality contributes to this process. It also brings the prospect of chiral-modified carbon nanostructures for biological and

Application of nanoarchitectonics in moist-electric generation

• Jia-Cheng Feng and
• Hong Xia

Beilstein J. Nanotechnol. 2022, 13, 1185–1200, doi:10.3762/bjnano.13.99

• liquids, the selection of ion-permeable membranes, and the effects of surface functional groups are discussed in detail in the paper and will not be repeated here. By adding an ion-selective membrane, ion concentration diffusion can take place in the fluid, not just in the bulk material. This innovation

Green synthesis of zinc oxide nanoparticles toward highly efficient photocatalysis and antibacterial application

• Vo Thi Thu Nhu,
• Nguyen Duy Dat,
• Le-Minh Tam and
• Nguyen Hoang Phuong

Beilstein J. Nanotechnol. 2022, 13, 1108–1119, doi:10.3762/bjnano.13.94

• , •O2−, O2 formed on the surface of ZnO NPs, will break bacterial cell membranes and enter the cells destroying organelles and ultimately inhibiting and shutting off bacteria metabolism [37][38]. The •OH radical is the most active oxidant which rapidly reacts with bacterial nucleic acids, lipids

• bacterial cell membranes, inhibiting amino acid metabolism and disrupting the bacterial cell enzymatic system [43][44][45]. Conclusion ZnO nanoparticles were synthesized by a green method using rosin extracted from Pinus latteri trees in Vietnam. The XRD diagram of synthesized ZnO showed that ZnO has the

Recent advances in green carbon dots (2015–2022): synthesis, metal ion sensing, and biological applications

• Aisha Kanwal,
• Naheed Bibi,
• Sajjad Hyder,
• Arif Muhammad,
• Hao Ren,
• Jiangtao Liu and
• Zhongli Lei

Beilstein J. Nanotechnol. 2022, 13, 1068–1107, doi:10.3762/bjnano.13.93

• by the use of vacuum filtration to separate the hydrothermal product. The hydrochar was refluxed in nitric and sulfuric acid, and dialysis membranes of different sizes were used to get CDs emitting four different colors, that is, blue, green, yellow, and red (Figure 7A,B) [118]. EDTA was used in a

Biomimetic chitosan with biocomposite nanomaterials for bone tissue repair and regeneration

• Se-Kwon Kim,
• Sesha Subramanian Murugan,
• Pandurang Appana Dalavi,
• Sebanti Gupta,
• Sukumaran Anil,
• Gi Hun Seong and
• Jayachandran Venkatesan

Beilstein J. Nanotechnol. 2022, 13, 1051–1067, doi:10.3762/bjnano.13.92

• Chemical Society. This content is not subject to CC BY 4.0. (a) The viability of mesenchymal stem cells in the developed electrospun membranes Live (green) and dead (red) staining of cells after 24 h of incubation. (b) Chitosan-based nanofibers without the addition of graphene oxide or (c) containing 1 wt

• % of graphene oxide. SEM images show the geometry of MSCs on the surface of membranes containing (d) 0% of graphene oxide, (e) 0.5% graphene oxide, (f) 1, (g) 1.5, and (h) 2% of graphene oxide. Figure 6 was reprinted from [72], Materials Science and Engineering: C, vol. 70, by N. Mahmoudi; A. Simchi

• , “On the biological performance of graphene oxide-modified chitosan/polyvinyl pyrrolidone nanocomposite membranes: In vitro and in vivo effects of graphene oxide”, pages 121–131, Copyright (2016), with permission from Elsevier. This content is not subject to CC BY 4.0. Alkaline phosphatase activity in

Bioselectivity of silk protein-based materials and their bio-inspired applications

• Hendrik Bargel,
• Vanessa T. Trossmann,
• Christoph Sommer and
• Thomas Scheibel

Beilstein J. Nanotechnol. 2022, 13, 902–921, doi:10.3762/bjnano.13.81

• and promotes their attachment to the bacterial surface/membrane residues [85]. HDPs have properties of cell-penetrating peptides and can translocate across membranes of prokaryotic, but also eukaryotic, cells [90]. The main mode of action of these peptides is promotion of adhesion through the cationic

• groups to the anionic bacterial membranes and their lipopolysaccharides (a component of the outer membrane of most Gram-negative bacteria), enabling insertion into the membrane driven by clusters of hydrophobic residues [85][91]. As a consequence, the microbial membranes are permeabilized, associated

• be used to generate self-assembled membranes, allowing for the adhesion of endothelial cells on the one side and smooth muscle cells on the other side, as well as the diffusion of relevant molecules, making this material promising for vascular tissue engineering [170]. In addition to flat films or