Nanocarrier systems loaded with IR780, iron oxide nanoparticles and chlorambucil for cancer theragnostics

• Phuong-Thao Dang-Luong,
• Hong-Phuc Nguyen,
• Loc Le-Tuan,
• Xuan-Thang Cao,
• Vy Tran-Anh and
• Hieu Vu Quang

Beilstein J. Nanotechnol. 2024, 15, 180–189, doi:10.3762/bjnano.15.17

• nanocarrier that can be loaded with the chemotherapeutic medication chlorambucil and magnetic resonance imaging agents (e.g., iron oxide nanoparticles and near-infrared fluorophore IR780) for theragnostics. Poly(lactic-co-glycolic acid) was combined with the aforementioned ingredients to generate poly(vinyl

• alcohol)-based nanoparticles (NPs) using the single emulsion technique. Then the NPs were coated with F127 and F127-folate by simple incubation for five days. The nanoparticles have the hydrodynamic size of approx. 250 nm with negative charge. Similar to chlorambucil and IR780, iron oxide loadings were

• of these systems to serve as medication and imaging agent carriers for cancer treatment and diagnostics, respectively. Keywords: cancer; chlorambucil; F127-folate; IR780; iron oxide nanoparticles; PLGA; theragnostics; Introduction Theragnostic nanoparticles (NPs) are a diagnostic and therapeutic

Ferromagnetic resonance spectra of linear magnetosome chains

• Elizaveta M. Gubanova and
• Nikolai A. Usov

Beilstein J. Nanotechnol. 2024, 15, 157–167, doi:10.3762/bjnano.15.15

• that of random clusters of interacting spherical magnetite nanoparticles. The shape of FMR spectra of both assemblies is shown to differ appreciably even at sufficiently large values of filling density of random clusters. Keywords: chains of magnetosomes; ferromagnetic resonance spectra; magnetite

• nanoparticles; numerical simulation; Introduction Magnetotactic bacteria are living organisms that grow within themselves magnetite nanoparticles called magnetosomes [1][2][3][4]. In contrast to chemically synthesized magnetite nanoparticles [5][6], magnetosomes have a perfect crystal structure, a narrow size

• distribution, and a high saturation magnetization close to that of bulk magnetite. In particular, magnetotactic bacteria M. gryphiswaldense produce linear chains of quasi-spherical magnetite nanoparticles with sizes ranging from 30 to 50 nm [1][2][7][8][9]. However, there are also magnetotactic bacteria that

CdSe/ZnS quantum dots as a booster in the active layer of distributed ternary organic photovoltaics

• Gabriela Lewińska,
• Piotr Jeleń,
• Zofia Kucia,
• Maciej Sitarz,
• Łukasz Walczak,
• Bartłomiej Szafraniak,
• Jerzy Sanetra and
• Konstanty W. Marszalek

Beilstein J. Nanotechnol. 2024, 15, 144–156, doi:10.3762/bjnano.15.14

• outstanding excitation and optimum charge transport in the mixture. Small-molecule materials, dyes, polymers, fullerenes, and ligands have been introduced as a third component so far. Quantum dots (QDs) are also beneficial materials for ternary solar cells. QDs and nanoparticles as zero-dimensional materials

• quantum dots and nanoparticles in organic solar cells has already been demonstrated [29][30][31][32][33][34]. The list of both materials and types, as well as applications, is not limited. Moreover, new quantum dots with innovative properties are still being researched and produced [35][36][37]. This

• nanoparticles, including the size of the shell (0.6 nm), and the core size declared by the manufacturer are included in Table 1. UV–vis spectroscopy was conducted with an Avantes Sensline Ava-Spec ULS-RS-TEC fiber-optic spectrophotometer and an Avantes AvaLight DH-S-BAL-Hal lamp. The absorption and luminescence

In situ optical sub-wavelength thickness control of porous anodic aluminum oxide

• Aleksandrs Dutovs,
• Raimonds Popļausks,
• Oskars Putāns,
• Vladislavs Perkanuks,
• Aušrinė Jurkevičiūtė,
• Tomas Tamulevičius,
• Uldis Malinovskis,
• Iryna Olyshevets,
• Donats Erts and
• Juris Prikulis

Beilstein J. Nanotechnol. 2024, 15, 126–133, doi:10.3762/bjnano.15.12

• zinc oxide nanorods embedded within the PAAO template [13]. Recently, it was demonstrated that the PAAO thickness tuning can increase the signal intensity and refractometric sensitivity of localized surface plasmon resonance (LSPR) sensors constructed using gold nanoparticles, which are deposited on

Assessing phytotoxicity and tolerance levels of ZnO nanoparticles on Raphanus sativus: implications for widespread adoptions

• Pathirannahalage Sahan Samuditha,
• Nadeesh Madusanka Adassooriya and
• Nazeera Salim

Beilstein J. Nanotechnol. 2024, 15, 115–125, doi:10.3762/bjnano.15.11

• Lanka 10.3762/bjnano.15.11 Abstract The escalating release of zinc oxide nanoparticles (ZnO NPs) into the environment poses a substantial threat, potentially leading to increased concentrations of zinc (Zn) in the soil and subsequent phytotoxic effects. This study aimed to assess the effects of ZnO NPs

• -tolerant species. Keywords: phytotoxicity; Raphanus sativus; ZnO nanoparticles; Zn tolerance; Zn toxicity; Introduction Despite zinc (Zn) being recognized as an important micronutrient for all living organisms, exceeding the permissible levels of Zn concentration due to anthropogenic sources can be

• efficient, novel sources of Zn fertilizers for cultivated crops through the integration of nanotechnology has been the focus of considerable research in the past decade [10]. Nanoparticles have garnered the interest of researchers, leading to their wide application in agriculture due to their enhanced

Development and characterization of potential larvicidal nanoemulsions against Aedes aegypti

• Jonatas L. Duarte,
• Leonardo Delello Di Filippo,
• Anna Eliza Maciel de Faria Mota Oliveira,
• Rafael Miguel Sábio,
• Gabriel Davi Marena,
• Tais Maria Bauab,
• Cristiane Duque,
• Vincent Corbel and
• Marlus Chorilli

Beilstein J. Nanotechnol. 2024, 15, 104–114, doi:10.3762/bjnano.15.10

• immune response with mammals. Furthermore, G. mellonella larvae have been successfully used to evaluate the acute toxicity of various nanoparticles and drugs [23]. The immune response of G. mellonella larvae can be evaluated by monitoring their survival rate and melanization response [24]. The aim of the

• drugs produced a web of oily/sticky nature, particularly at higher concentrations, which persisted up to day 2. The absence of acute toxicity of nanoparticles on G. mellonella larvae is consistent with previous observations [53][54]. Overall, the results suggest that the NEs are not toxic to the larvae

New application of bimetallic Ag/Pt nanoplates in a colorimetric biosensor for specific detection of E. coli in water

• Azam Bagheri Pebdeni,
• Mohammad N. AL-Baiati and
• Morteza Hosseini

Beilstein J. Nanotechnol. 2024, 15, 95–103, doi:10.3762/bjnano.15.9

• . However, these procedures need a significant amount of time, skilled operators, and costly equipment. As a result, for effective medical treatment with minimal detection time, a selective and sensitive detection strategy is required [5][6]. New nanoparticles for fast bacterial detection can be fabricated

• ]. Nanomaterials have improved the ability to detect pathogens in water and food by enhancing signals and sensitivity. These materials, which encompass nanoparticles, nanorods, nanowires, and nanoclusters, can be combined with aptamers, antibodies, enzymes, and other ligands to display unique physical, chemical

• nanoparticles (i.e., silver nanoplates, Ag NPLs) covered with a layer of Pt atoms to improve the peroxide activity of NPLs, and use them as colorimetric biosensor materials. Metallic NPLs were employed in a variety of applications, including antibacterial activity [17][18][19], hazardous dye removal [20

Berberine-loaded polylactic acid nanofiber scaffold as a drug delivery system: The relationship between chemical characteristics, drug-release behavior, and antibacterial efficiency

• Le Thi Le,
• Hue Thi Nguyen,
• Liem Thanh Nguyen,
• Huy Quang Tran and
• Thuy Thi Thu Nguyen

Beilstein J. Nanotechnol. 2024, 15, 71–82, doi:10.3762/bjnano.15.7

• Sciences, Phenikaa University, Hanoi 12116, Vietnam 10.3762/bjnano.15.7 Abstract Hydrophobic berberine powder (BBR) and hydrophilic BBR nanoparticles (BBR NPs) were loaded into an electrospun polylactic acid (PLA) nanofiber scaffold for modulating the release behavior of BBR in an aqueous medium. The BBR

• been employed to produce nanoformulations of drugs for endowing a better therapeutic effect. The nanoformulations for drug delivery can be designed using nanocarrier systems, including organic materials (liposomes, nanoemulsions, nanomicelles, and nanofibers) and inorganic nanoparticles (gold, silver

• , iron oxide, and mesoporous silica nanoparticles) [4]. Additionally, nanocarrier-free systems, such as drug nanocrystals, are also used to improve the delivery of poorly soluble drugs [5][6]. In our previous study, the saturation concentration of BBR in water was 2.0 mg/mL, while BBR nanoparticles

Influence of conductive carbon and MnCo₂O₄ on morphological and electrical properties of hydrogels for electrochemical energy conversion

• Sylwia Pawłowska,
• Karolina Cysewska,
• Yasamin Ziai,
• Jakub Karczewski,
• Piotr Jasiński and
• Sebastian Molin

Beilstein J. Nanotechnol. 2024, 15, 57–70, doi:10.3762/bjnano.15.6

• , drugs, metal nanoparticles, metal oxide nanoparticles, carbon nanotubes, or biomolecules. This is a very important advantage that opens ways of designing composite hydrogels with various properties and applications such as biomedical [8][9][10], biosensors [11][12][13], wearable electronics [14][15][16

• appropriate electrical conductivity [22]. Suspension of conductive fillers in the hydrogel structure, such as metallic particles (gold nanoparticles, silver nanoparticles) [23][24][25], carbon-based materials (GO graphene oxide, CNT carbon nanotubes) [26][27][28], and conductive polymers (polyaniline

• ]. Cai et al. found some silver nanoparticles only slightly present in the skeleton of a PVA@DEL composite hydrogel [23]. Most of the Ag nanoparticles were observed in the wall of the hydrogel network. In our case, for the Hgel-MCO-cCB 1:3 sample, when the volume percentage of cCB was 17.1% (Table 3

Curcumin-loaded nanostructured systems for treatment of leishmaniasis: a review

• Douglas Dourado,
• Thayse Silva Medeiros,
• Éverton do Nascimento Alencar,
• Edijane Matos Sales and
• Fábio Rocha Formiga

Beilstein J. Nanotechnol. 2024, 15, 37–50, doi:10.3762/bjnano.15.4

• systems [19], nanoparticles [20], nanoliposomes [21], micelles [22], and nanocrystals [23] have been utilized. These systems can promote (i) protection of the drug against degradation in physiological media, (ii) increase in drug solubility, and (iii) modification/targeting of the drug enabling transport

• these carriers with the macrophage membrane. As a result, the macrophages uptake the drug-loaded nanocarrier by phagocytosis, where they will directly act on the parasites [65][66][67]. Several types of nanosystems have been studied for carrying antileishmanial drugs, such as polymeric nanoparticles

• , lipid nanoparticles, nano- and microemulsions, liposomes, or metallic nanoparticles [68]. Costa-Lima and colleagues incorporated bisnaphthalimidopropyldiaaminooctane (BNIPDaoct) into PLGA polymeric nanoparticles and obtained particles with sizes around 150 nm, with encapsulation efficiency around 90

Nanotechnological approaches in the treatment of schistosomiasis: an overview

• Lucas Carvalho,
• Michelle Sarcinelli and
• Beatriz Patrício

Beilstein J. Nanotechnol. 2024, 15, 13–25, doi:10.3762/bjnano.15.2

• bioavailability and resistance. In this context, nanoparticles have emerged as a promising option for improving schistosomiasis treatment. Several narrative reviews have been published on this topic. Unfortunately, the lack of clear methodologies presented in these reviews leads to the exclusion of many important

• only original research articles that used nanoparticles smaller than 1 µm in the treatment context. Additionally, a search was conducted in the references of the identified articles to retrieve works that could not be found solely using the original search formula. As a result, 65 articles that met the

• established criteria were identified. Inorganic and polymeric nanoparticles were the most prevalent nanosystems used. Gold was the primary material used to produce inorganic nanoparticles, while poly(lactic-co-glycolic acid) and chitosan were commonly used to produce polymeric nanoparticles. None of these

Fluorescent bioinspired albumin/polydopamine nanoparticles and their interactions with Escherichia coli cells

• Eloïse Equy,
• Jordana Hirtzel,
• Sophie Hellé,
• Béatrice Heurtault,
• Eric Mathieu,
• Morgane Rabineau,
• Vincent Ball and
• Lydie Ploux

Beilstein J. Nanotechnol. 2023, 14, 1208–1224, doi:10.3762/bjnano.14.100

• , France UMR 7199, CNRS/University of Strasbourg, 74 route du Rhin, 67401 Illkirch, France CNRS, 23 rue du Loess, 67200 Strasbourg, France 10.3762/bjnano.14.100 Abstract Inspired by the eumelanin aggregates in human skin, polydopamine nanoparticles (PDA NPs) are promising nanovectors for biomedical

• labelled BSA/PDA NPs to track bacteria and carry drugs in the core of bacterial cells. Keywords: accumulation; albumin; antibacterial; Escherichia coli; fluorescence; nanoparticles; penetration; polydopamine; Introduction Organic nanoparticles (ONPs) are used to target and deliver drugs to tissue and

• of antimicrobial resistance of bacteria [5], this appears as a promising route to deliver antimicrobials while reducing the drug doses and subsequent harmful side effects in antibacterial applications. To this end, different types of ONPs have been used, such as liposomes [6] and nanoparticles (NPs

A combined gas-phase dissociative ionization, dissociative electron attachment and deposition study on the potential FEBID precursor [Au(CH₃)₂Cl]₂

• Elif Bilgilisoy,
• Ali Kamali,
• Thomas Xaver Gentner,
• Gerd Ballmann,
• Sjoerd Harder,
• Hans-Peter Steinrück,
• Hubertus Marbach and
• Oddur Ingólfsson

Beilstein J. Nanotechnol. 2023, 14, 1178–1199, doi:10.3762/bjnano.14.98

• selected area of the SEM image shown in Figure 1a is depicted in Figure 1c, where nanoparticles in the deposition are noticeable, although the picture is somewhat blurry. To better visualize the observed nanoparticles, a background subtraction was performed with the image enhancement program ImageJ [35

• ]. The image after the background subtraction is shown in Figure 1d, where the particles can be more clearly distinguished. After background subtraction, some of the deposited nanoparticles appear facetted; however, the majority are spherical. HAADF-STEM on FEBID (SiO2 (500 nm)/Si(111)) As a next step

• , high-angle annular dark-field scanning transmission electron microscopy (HAADF-STEM) was performed to analyze the morphology of the deposited nanoparticles. For this purpose, several FEBID structures were prepared on the SiO2 substrate with the size of 4 × 4 µm2 and an electron dose of 7.80 C/cm2. For

Elasticity, an often-overseen parameter in the development of nanoscale drug delivery systems

• Agnes-Valencia Weiss and
• Marc Schneider

Beilstein J. Nanotechnol. 2023, 14, 1149–1156, doi:10.3762/bjnano.14.95

• Agnes-Valencia Weiss Marc Schneider Department of Pharmacy, Biopharmaceutics and Pharmaceutical Technology, Saarland University, Campus C4 1, Saarbruecken, Germany 10.3762/bjnano.14.95 Abstract Nanoparticles have shown an enormous potential as drug delivery systems in the lab. However

• drug delivery can be achieved, are mechanical properties of nanoparticles. Even though this is often not even considered during formulation development, and it is not requested for approval, an increasing number of studies show that it is important to have knowledge about these characteristics. In this

• properties of drug carriers. Keywords: atomic force microscopy; drug delivery; elasticity; mechanical properties; nanomedicine; nanoparticles; stiffness measurement; tissue/body distribution; Introduction Drug delivery systems are developed with the aim to transport a given drug to the site of action

Curcumin-loaded albumin submicron particles with potential as a cancer therapy: an in vitro study

• Nittiya Suwannasom,
• Netsai Sriaksorn,
• Chutamas Thepmalee,
• Krissana Khoothiam,
• Ausanai Prapan,
• Hans Bäumler and
• Chonthida Thephinlap

Beilstein J. Nanotechnol. 2023, 14, 1127–1140, doi:10.3762/bjnano.14.93

• stability and solubility [9]. The complexation occurs mainly through hydrophobic interactions in protein cavities [10][11]. In a recent study, zein nanoparticles loaded with CUR have been studied for their potential in treating brain tumors, and the results have demonstrated a reduction in the proliferation

• and migration of C6 glioma cells in vitro [12]. Other nanoparticles that are being explored as CUR formulations for various applications include silk-based nanoparticles. These are an excellent candidate with longer plasma half-life and slower release rate, indicating high bioavailability [13]. The

• silk core–shell nanoparticles show high cytotoxicity and cellular uptake regarding breast cancer cells [14]. However, the effectiveness of zein nanoparticles as a delivery vehicle is limited by their poor stability, as they tend to aggregate when suspended in water [15]. Lyophilizing the particles

Sulfur nanocomposites with insecticidal effect for the control of Bactericera cockerelli

• Lany S. Araujo-Yépez,
• Juan O. Tigrero-Salas,
• Vicente A. Delgado-Rodríguez,
• Vladimir A. Aguirre-Yela and
• Josué N. Villota-Méndez

Beilstein J. Nanotechnol. 2023, 14, 1106–1115, doi:10.3762/bjnano.14.91

• de Nanociencia y Nanotecnología (CENCINAT), Universidad de las Fuerzas Armadas – ESPE, Av. General Rumiñahui 171-5-231B, Sangolquí, PO Box 171-5-231B, Ecuador 10.3762/bjnano.14.91 Abstract The purpose of this research was to synthesize nanocomposites consisting of sulfur nanoparticles coated with

• eucalyptus and rosemary essential oils to determine the insecticidal effect in the control of nymphs of paratrioza (Bactericera cockerelli (Sulc) (Hemiptera: Triozidae)) in potato crops. A solution of thiosulfate was reduced to elemental sulfur, and the sulfur nanoparticles were coated with eucalyptus and

• development of new nanoinsecticides to combat pests in a more productive, cost-effective, and eco-friendly way [8][12]. Nanoscale agricultural products are developed using nanotechnology, such as nanopesticides, nanoinsecticides, nanoemulsions, and nanoparticles, to reduce the use of toxic chemicals [14

Experimental investigation of usage of POE lubricants with Al₂O₃, graphene or CNT nanoparticles in a refrigeration compressor

• Kayhan Dağıdır and
• Kemal Bilen

Beilstein J. Nanotechnol. 2023, 14, 1041–1058, doi:10.3762/bjnano.14.86

• nanotubes (CNTs) at different mass fractions in a refrigeration compressor was experimentally investigated. The required electrical power of the compressor was measured to determine the effect of the use of nanolubricants. Nanoparticles used in the preparation of nanolubricants were gradually added to the

• operating conditions of this study. As a result, the required electrical power of the compressor decreased by 6.26, 6.82, and 5.55% with the addition of Al2O3, graphene, and CNT nanoparticles at optimum mass fractions of 0.750, 0.250, and 0.250% to the lubricant, respectively, compared to the compressor

• increasing nanoparticle fraction. In conclusion, nanolubricants containing nanoparticles above the optimum mass fraction increase the required electrical power of the compressor. It is concluded that nanoparticle fractions should not be used above the optimum value in nanolubricant applications. Keywords

Recognition mechanisms of hemoglobin particles by monocytes – CD163 may just be one

• Jonathan-Gabriel Nimz,
• Pichayut Rerkshanandana,
• Chiraphat Kloypan,
• Ulrich Kalus,
• Saranya Chaiwaree,
• Axel Pruß,
• Radostina Georgieva,
• Yu Xiong and
• Hans Bäumler

Beilstein J. Nanotechnol. 2023, 14, 1028–1040, doi:10.3762/bjnano.14.85

• arise spontaneously from C3 by hydrolysis, could be considered here. Moghimi et al. report numerous possible interactions of the complement system with, among others, nanoparticles as a drug delivery system [44]. The authors also discussed the possible effects of spontaneously forming water shells and

A visible-light photodetector based on heterojunctions between CuO nanoparticles and ZnO nanorods

• Doan Nhat Giang,
• Nhat Minh Nguyen,
• Duc Anh Ngo,
• Thanh Trang Tran,
• Le Thai Duy,
• Cong Khanh Tran,
• Thi Thanh Van Tran,
• Phan Phuong Ha La and
• Vinh Quang Dang

Beilstein J. Nanotechnol. 2023, 14, 1018–1027, doi:10.3762/bjnano.14.84

• , have gained much attention from many research teams. This study describes a low-cost photodetector based on CuO nanoparticles and ZnO nanorods operating in a wide range of light wavelengths (395, 464, 532, and 640 nm). Particularly, under 395 nm excitation, the heterostructure device exhibits high

• nanoparticles and ZnO nanorods obtained via a simple and cost-effective synthesis process has great potential for optoelectronic applications. Keywords: CuO nanoparticles; heterojunction; optoelectronics; visible-light photodetector; ZnO nanorods; Introduction Optoelectronics is a field to accelerate the

• photodetector based on CuO nanoparticles (CuO NPs) and ZnO nanorods (ZnO NRs). CuO NPs were loaded onto ZnO NRs by a cost-effective, simple hydrothermal method at low synthesis temperature [38]. The CuO/ZnO photodetector was characterized, and its sensitivity was evaluated regarding visible-light wavelengths

Nanoarchitectonics of photothermal materials to enhance the sensitivity of lateral flow assays

• Elangovan Sarathkumar,
• Rajasekharan S. Anjana and
• Ramapurath S. Jayasree

Beilstein J. Nanotechnol. 2023, 14, 988–1003, doi:10.3762/bjnano.14.82

• assays (LFAs) are currently the most widely used point-of-care testing technique with remarkable advantages such as simple operation, rapid analysis, portability, and low cost. Traditionally, gold nanoparticles are employed as tracer element in LFAs due to their strong localised surface plasmon resonance

• different parts, namely sample pad, conjugate pad, nitrocellulose membrane, and adsorbent pad, maintaining a smooth flow of reagents through the LFA membrane. In the presence of a sample, the analyte initially reacts with affinity molecules, commonly antibodies linked with tracers such as gold nanoparticles

• , before being captured by immobilized biomolecules on a test line in the nitrocellulose membrane [6][7]. In conventional LFAs, most commonly gold nanoparticles and coloured cellulose nanobeads have been used as tracer elements because of strong light absorption and surface plasmon resonance, which yield

Isolation of cubic Si₃P₄ in the form of nanocrystals

• Polina K. Nikiforova,
• Sergei S. Bubenov,
• Vadim B. Platonov,
• Andrey S. Kumskov,
• Nikolay N. Kononov,
• Tatyana A. Kuznetsova and
• Sergey G. Dorofeev

Beilstein J. Nanotechnol. 2023, 14, 971–979, doi:10.3762/bjnano.14.80

• nanoparticles with a defective zinc blende structure under mild conditions through thermal annealing of hydrogenated silicon nanoparticles with red phosphorus. The synthesized Si3P4 nanoparticles were analyzed using FTIR, XRD, electron diffraction, EDX, TEM, Raman spectroscopy, X-ray fluorescence spectrometry

• , and UV–vis spectrophotometry. For the isolated cubic Si3P4 phase, a cell parameter of a = 5.04 Å was determined, and the bandgap was estimated to be equal to 1.25 eV. Because of the nanoscale dimensions of the obtained Si3P4 nanoparticles, the product may exhibit several exceptional properties as a

• calculations; semiconductor nanocrystals; silicon phosphide; Introduction Advancements in electronics and related fields are calling for new ways of synthesizing compounds. Subsequently, recognizing and utilizing the special properties of nanoparticles (NPs) of new materials using emerging methods offers a

Metal-organic framework-based nanomaterials for CO₂ storage: A review

• Ha Huu Do,
• Iqra Rabani and
• Hai Bang Truong

Beilstein J. Nanotechnol. 2023, 14, 964–970, doi:10.3762/bjnano.14.79

• prepare Cu-based MOF nanoparticles (UHM-30) for gas storage, as depicted in Figure 2 [27]. The benefit of this strategy is the generation of both OMSs and LBCs, resulting in an enhanced CO2 adsorption capacity for UHM-30 (5.26 mmol·g−1) compared to HKUST-1 (4.69 mmol·g−1). The effectiveness of amino

• . In a recent study, Gaikwad et al. modified MOF-177 nanoparticles using three different amines to enhance the amount of absorbed CO2 [37]. The optimally functionalized MOF-177, employing tetraethylenepentamine (TEPA), exhibited a remarkably higher amount of absorbed CO2 than bare MOF-177 under the

Prediction of cytotoxicity of heavy metals adsorbed on nano-TiO₂ with periodic table descriptors using machine learning approaches

• Joyita Roy,
• Souvik Pore and
• Kunal Roy

Beilstein J. Nanotechnol. 2023, 14, 939–950, doi:10.3762/bjnano.14.77

• Joyita Roy Souvik Pore Kunal Roy Drug Theoretics and Cheminformatics Laboratory, Department of Pharmaceutical Technology, Jadavpur University, Kolkata, 700032, India 10.3762/bjnano.14.77 Abstract Nanoparticles with their unique features have attracted researchers over the past decades. Heavy

• metals, upon release and emission, may interact with different environmental components, which may lead to co-exposure to living organisms. Nanoscale titanium dioxide (nano-TiO2) can adsorb heavy metals. The current idea is that nanoparticles (NPs) may act as carriers and facilitate the entry of heavy

• present work manifests that ML in conjunction with periodic table descriptors can be used to explore the features and predict unknown compounds with similar properties. Keywords: heavy metals; HK-2 cell; ML algorithm; periodic table descriptors; QSAR; Introduction Nanoparticles (NPs) have gained much

Antibody-conjugated nanoparticles for target-specific drug delivery of chemotherapeutics

• Mamta Kumari,
• Amitabha Acharya and
• Praveen Thaggikuppe Krishnamurthy

Beilstein J. Nanotechnol. 2023, 14, 912–926, doi:10.3762/bjnano.14.75

• of nanoscale chemotherapeutics is accomplished by two different approaches, namely the exploitation of leaky tumor vasculature (EPR effect) and the surface modification of nanoparticles (NPs) with various tumor-homing peptides, aptamers, oligonucleotides, and monoclonal antibodies (mAbs). Because of

• higher binding affinity and specificity, mAbs have received a lot of attention for the detection of selective cancer biomarkers and also for the treatment of various types of cancer. Antibody-conjugated nanoparticles (ACNPs) are an effective targeted therapy for the efficient delivery of

• -directed enzyme prodrug therapy, small molecule drug conjugates, and others are being investigated [2][3]. Targeted delivery with nanoparticles (NPs) has received a lot of attention because it reduces toxicity while also providing good drug compatibility and loadability. Furthermore, NPs increase drug

Ni, Co, Zn, and Cu metal-organic framework-based nanomaterials for electrochemical reduction of CO₂: A review

• Ha Huu Do and
• Hai Bang Truong

Beilstein J. Nanotechnol. 2023, 14, 904–911, doi:10.3762/bjnano.14.74

• within MOFs, thereby enhancing the CO2RR process. Besides, MOFs could be used as ideal precursors for the controlled dispersion of metal nanoparticles within organic frameworks, either through operational conditions or via the pyrolysis technique, thereby promoting efficient CO2 reduction [35][36]. The

• ]. Cu nanoparticles were created during when the CuII/ade-MOFs reconstructed and act as active centers for CO2 reduction to CH4 and C2H4. Conclusion and Outlook MOFs were recognized as promising nanomaterials for the transformation of CO2 into valuable products through electrochemical processes. This