Enhancement of the piezoelectric coefficient in PVDF-TrFe/CoFe₂O₄ nanocomposites through DC magnetic poling

• Marco Fortunato,
• Alessio Tamburrano,
• Maria Paola Bracciale,
• Maria Laura Santarelli and
• Maria Sabrina Sarto

Beilstein J. Nanotechnol. 2021, 12, 1262–1270, doi:10.3762/bjnano.12.93

•  6b,c shows the aggregation of CoFe2O4 nanoparticles in some areas, in analogy with what has been reported in [25]. The formation of aggregates was confirmed by energy-dispersive X-ray spectroscopy (EDX). In correspondence with the agglomeration we observed a higher intensity of the O, Fe, and Co

• magnetic field of 50 mT was applied, while for higher values of magnetic fields the d33 value tends to decrease. This could be due to the aggregation of the CoFe2O4 nanoparticles forced by intense magnetic fields, resulting in a reduced alignment efficiency of the polymeric chains, as suggested in [25

Morphology-driven gas sensing by fabricated fractals: A review

• Vishal Kamathe and
• Rupali Nagar

Beilstein J. Nanotechnol. 2021, 12, 1187–1208, doi:10.3762/bjnano.12.88

• D is then estimated by [43][51]: This analysis also predicts the power law governing the growth within the fractal space. Growth of fractals in unique geometrical patterns has been predominantly a subject of theoretical treatment. The diffusion-limited aggregation (DLA) model was proposed in 1981

• , better sensing characteristics can be expected. Thus, fractal geometries show great prospect to be considered as sensor templates, regardless of the used material. The nucleation, growth, and diffusion-limited aggregation of nanoparticles results in the formation of interesting fractal morphologies with

• length scales depicting the change in fractal geometry as a function of the fractal dimensions D and L. Figure 2a was adapted with permission from [48], © 2009 Geological Society of Malaysia. This content is not subject to CC BY 4.0 (b) Diffusion-limited aggregation. Random aggregate of 3600 particles on

Irradiation-driven molecular dynamics simulation of the FEBID process for Pt(PF₃)₄

• Alexey Prosvetov,
• Alexey V. Verkhovtsev,
• Gennady Sushko and
• Andrey V. Solov’yov

Beilstein J. Nanotechnol. 2021, 12, 1151–1172, doi:10.3762/bjnano.12.86

• molecule, on a SiO2 surface. The simulations reveal the processes driving the initial phase of nanostructure formation during FEBID, including the nucleation of Pt atoms and the formation of small metal clusters on the surface, followed by their aggregation and the formation of dendritic platinum

• process, including nucleation of Pt atoms, formation of small metal clusters on the surface followed by their aggregation, and eventually, the formation of dendritic platinum nanostructures. The morphology of the nanostructures grown during the FEBID process has not yet been thoroughly investigated on the

• number of PF3 ligands attached due to lower fragmentation probability in this region. The presence of the ligands prevents dense packing and aggregation of isolated metal clusters. As a result, the height of the deposited structures in this region is higher than that within the beam spot area. The region

Self-assembly of amino acids toward functional biomaterials

• Huan Ren,
• Lifang Wu,
• Lina Tan,
• Yanni Bao,
• Yuchen Ma,
• Yong Jin and
• Qianli Zou

Beilstein J. Nanotechnol. 2021, 12, 1140–1150, doi:10.3762/bjnano.12.85

• cancer cells [50]. Furthermore, naphthalimide (NI) derivatives can also be used as end-capping materials for amino acids. Naphthalimide has unique photophysical properties and photostability as a luminescent material for aggregation-induced emission (AIE), which can display high emission properties in

• the aggregated state and can be used for imaging [51]. Importantly, NI exhibits hydrophobicity and π–π stacking due to the aromatic moieties, and is prone to dynamic aggregation, which can be used in self-assembled construction units [52]. For example, Hsu et al. [53] self-assembled NI and

• , indicating that hMSCs had a high viability in the supramolecular hydrogel formed by NI-Phe. Sarkar et al. synthesized amphiphilic molecules containing NI and histidine which formed fluorescent organic nanoparticles with J-aggregation in water/DMSO, exhibiting high emissivity upon aggregation. These particles

pH-driven enhancement of anti-tubercular drug loading on iron oxide nanoparticles for drug delivery in macrophages

• Karishma Berta Cotta,
• Sarika Mehra and
• Rajdip Bandyopadhyaya

Beilstein J. Nanotechnol. 2021, 12, 1127–1139, doi:10.3762/bjnano.12.84

• deployment in drug delivery is contingent upon controlled drug loading and a desired release profile, with simultaneous biocompatibility and cellular targeting. Iron oxide nanoparticles (IONPs), being biocompatible, are used as drug carriers. However, to prevent aggregation of bare IONPs, they are coated

• , with reduced size or aggregation [11][13][14]. In this regard, the use of drugs as both a stabilizing agent and an antibiotic could prove to be beneficial. To this end, an understanding of drug–nanoparticle interactions can enable the identification of key parameters for optimal drug loading and drug

• File 1, Table S1). Characterization of uncoated iron oxide nanoparticles and NOR Uncoated iron oxide nanoparticles (UIONPs) exhibited a hydrodynamic diameter (from DLS) greater than 1000 nm, which was due to the aggregation of ≈10 nm individual UIONPs, as observed by TEM (Figure 2a,b). The size

Revealing the formation mechanism and band gap tuning of Sb₂S₃ nanoparticles

• Maximilian Joschko,
• Franck Yvan Fotue Wafo,
• Christina Malsi,
• Danilo Kisić,
• Ivana Validžić and
• Christina Graf

Beilstein J. Nanotechnol. 2021, 12, 1021–1033, doi:10.3762/bjnano.12.76

• and 35 nm (Figure 4b), with the particle fraction of a size around 35 nm found more frequently (Figure 4c). Together with the finding that the type I nanoparticles were also around 35 nm in diameter (see Figure 1), this led to the assumption that there was an aggregation and merging step from the type

The role of deep eutectic solvents and carrageenan in synthesizing biocompatible anisotropic metal nanoparticles

• Nabojit Das,
• Akash Kumar and
• Raja Gopal Rayavarapu

Beilstein J. Nanotechnol. 2021, 12, 924–938, doi:10.3762/bjnano.12.69

• , and morphology of the products in chemical synthesis. This is also evident from the studies tabulated in Table 2, where the obtained shapes are given together with the eutectic mixture and precursor material used [79][80][81][82][83][84][85][86][87]. The aggregation/agglomeration of nanoparticles in

• stability of the nanoparticles is governed by the capping agent, which prevents the aggregation of nanoparticles. Several capping agents such as CTAB, citrate, polymers, and carbohydrates are extensively used to stabilize nanoparticles in their colloidal state [99]. The capping agents govern the

• aggregation and sedimentation above pH 5 [117]. The stability was enhanced upon adhesion of carrageenan to the nanoparticle surface rendering it negatively charged. Although there are little reports on using carrageenan as a safe and sustainable component for synthesizing plasmonic metal nanomaterials, the

Modification of a SERS-active Ag surface to promote adsorption of charged analytes: effect of Cu²⁺ ions

• Bahdan V. Ranishenka,
• Andrei Yu. Panarin,
• Irina A. Chelnokova,
• Sergei N. Terekhov,
• Peter Mojzes and
• Vadim V. Shmanai

Beilstein J. Nanotechnol. 2021, 12, 902–912, doi:10.3762/bjnano.12.67

• , caused aggregation of the resulting positively charged Ag NPs. Nevertheless, the proposed approach enabled the successful analysis of a number of negatively charged analytes. Silver NPs treated with polyethylenimine, spermine, or spermidine were successfully used for the detection of negatively charged

• absence of NP aggregation in the presence of multicharged metal ions. Considering the strong tendency of multicharged ions to destabilize colloidal systems [26][27][28] even at low concentrations, this observation is surprising. It should be noted that it is difficult to control the aggregation of NPs in

• possible to exploit different techniques of functionalization. To avoid different effects related to the aggregation of NPs we used Ag NPs immobilized by adsorption as a convenient and reproducible SERS substrate for the investigation of the chemical treatment of the Ag surface with different reagents. To

The role of convolutional neural networks in scanning probe microscopy: a review

• Ido Azuri,
• Irit Rosenhek-Goldian,
• Neta Regev-Rudzki,
• Georg Fantner and
• Sidney R. Cohen

Beilstein J. Nanotechnol. 2021, 12, 878–901, doi:10.3762/bjnano.12.66

Comprehensive review on ultrasound-responsive theranostic nanomaterials: mechanisms, structures and medical applications

• Sepand Tehrani Fateh,
• Lida Moradi,
• Elmira Kohan,
• Michael R. Hamblin and
• Amin Shiralizadeh Dezfuli

Beilstein J. Nanotechnol. 2021, 12, 808–862, doi:10.3762/bjnano.12.64

• work by King provided the mathematical basis [93]. The ARF can be divided into primary and secondary forces. Primary forces are applied to single particles, while secondary forces cause particle–particle interactions. Moreover, primary forces cause migration and aggregation of the particles in an

Silver nanoparticles nucleated in NaOH-treated halloysite: a potential antimicrobial material

• Yuri B. Matos,
• Rodrigo S. Romanus,
• Mattheus Torquato,
• Edgar H. de Souza,
• Rodrigo L. Villanova,
• Marlene Soares and
• Emilson R. Viana

Beilstein J. Nanotechnol. 2021, 12, 798–807, doi:10.3762/bjnano.12.63

• antimicrobial surface activity obtained with Ag/HNT-8/DIO is consistent with expectations, as well dispersed nanoparticles tend to have higher surface energy. The difference in aggregation between both samples may be explained in terms of matrix polarity. Polymer molecules are polarized to some degree

Silver nanoparticles induce the cardiomyogenic differentiation of bone marrow derived mesenchymal stem cells via telomere length extension

• Khosro Adibkia,
• Ali Ehsani,
• Asma Jodaei,
• Ezzatollah Fathi,
• Raheleh Farahzadi and
• Mohammad Barzegar-Jalali

Beilstein J. Nanotechnol. 2021, 12, 786–797, doi:10.3762/bjnano.12.62

• present in the solution. The aggregation of NPs depends on the type and amount of ions present in the solutions. In one study, Stebounova et al. concluded that Ag-NPs form aggregates and agglomerates when presented to high ionic fluids. Less than 10 mg/L of Ag-NPs remains suspended, and the rest forms

Recent progress in magnetic applications for micro- and nanorobots

• Ke Xu,
• Shuang Xu and
• Fanan Wei

Beilstein J. Nanotechnol. 2021, 12, 744–755, doi:10.3762/bjnano.12.58

• nanoparticle aggregation in the absence of a magnetic field. This allows the gated compartments to form only in the presence of a magnetic field (ca. 0.4 T), creating a stimuli-responsive nanoreactor. The activated nanoreactor produces a signal only when (i) a second species of magnetic beads, MaB2 carrying F

Prediction of Co and Ru nanocluster morphology on 2D MoS₂ from interaction energies

• Cara-Lena Nies and
• Michael Nolan

Beilstein J. Nanotechnol. 2021, 12, 704–724, doi:10.3762/bjnano.12.56

• activation energies for 2D or 3D clusters will give a more detailed insight into the processes that control aggregation on the surface. However, this is out of the scope of the current study. Based on our findings MoS2 would be most suitable as a barrier+liner for a Co interconnect, although based on our

Fate and transformation of silver nanoparticles in different biological conditions

• Barbara Pem,
• Marija Ćurlin,
• Darija Domazet Jurašin,
• Valerije Vrček,
• Rinea Barbir,
• Vedran Micek,
• Raluca M. Fratila,
• Jesus M. de la Fuente and
• Ivana Vinković Vrček

Beilstein J. Nanotechnol. 2021, 12, 665–679, doi:10.3762/bjnano.12.53

• vivo settings. Keywords: animal tissue; biological media; nanoparticle aggregation; nanoparticle dissolution; nanoparticle reformation; silver nanoparticles; Introduction The global consumption of silver nanoparticles (AgNPs) has been steadily increasing in the last decade and estimated to reach over

• will not be retained in biological media [9][10][11][12][13][14]. In biological media, AgNPs may be transformed into different forms by aggregation, agglomeration, dissolution, interaction with biomolecules, or generation of reactive oxygen species (ROS) that may lead to the coexistence of

• such conditions, the repulsive electrostatic forces between particles with the same surface charge are weakened, leading to aggregation upon collision [10]. The AgNPs with bulky coatings are less sensitive to this, since their stabilisation is steric and not electrostatic [14]. The dissolution of AgNPs

Rapid controlled synthesis of gold–platinum nanorods with excellent photothermal properties under 808 nm excitation

• Jialin Wang,
• Qianqian Duan,
• Min Yang,
• Boye Zhang,
• Li Guo,
• Pengcui Li,
• Wendong Zhang and
• Shengbo Sang

Beilstein J. Nanotechnol. 2021, 12, 462–472, doi:10.3762/bjnano.12.37

• coverage on the AuNRs [40]. The Au@Pt NRs dispersed well in water without notable aggregation, as shown in Figure 1e. In this paper, we do not conduct a detailed study on the action mechanism of Ag+ in the process of Au@Pt NRs synthesis, but rather focus on the practical consequences for the synthesized

A review on nanostructured silver as a basic ingredient in medicine: physicochemical parameters and characterization

• Gabriel M. Misirli,
• Kishore Sridharan and
• Shirley M. P. Abrantes

Beilstein J. Nanotechnol. 2021, 12, 440–461, doi:10.3762/bjnano.12.36

• are very close to each other. In this regard, the electrons could be described as waves, as depicted in Figure 5 [64]. The type of metal, size, shape, the molecules attached to the surface, and the degree of aggregation of the particles determine the energy range (frequency) of the light that can

• aggregation, physicochemical or biological synthesis methods used, chemical nature of the coating, surface charge, and free Ag+ content. The quality control of AgNPs is necessary to guarantee their suitability for the intended use, reproducibility, efficacy, and low toxicity [146]. Another important point is

• complementary way, the size, distribution, shape heterogeneity, morphology, dispersion, and aggregation can be directly evaluated via TEM in which the high spatial resolution facilitates the investigation of the electronic structure and chemical composition [156]. However, the disadvantages other than the

Colloidal particle aggregation: mechanism of assembly studied via constructal theory modeling

• Scott C. Bukosky,
• Sukrith Dev,
• Monica S. Allen and
• Jeffery W. Allen

Beilstein J. Nanotechnol. 2021, 12, 413–423, doi:10.3762/bjnano.12.33

• with respect to van der Waals and double layer interactions. Preliminary results show that the particle aggregation behavior depends on the initial lattice configuration and solvent properties. Ultimately, our model provides the first constructal framework for predicting the self-assembly of particles

• -cleaning devices [12]. It was concluded that the maximum collection rate was achieved when the aerosol particles first formed into clusters and then dendrites in order to balance their electrostatic forces. The aggregation of colloidal particles (small particles or droplets typically between 10 nm and 10

• /implemented to describe the assembly of colloidal particles. In this article, we use said theory to predict the effect of varying system parameters on the magnitude of the total DLVO force for two scenarios, that is, uniform and non-uniform aggregation. The constructal approach presented here provides a

Characterization, bio-uptake and toxicity of polymer-coated silver nanoparticles and their interaction with human peripheral blood mononuclear cells

• Sahar Pourhoseini,
• Reilly T. Enos,
• Angela E. Murphy,
• Bo Cai and
• Jamie R. Lead

Beilstein J. Nanotechnol. 2021, 12, 282–294, doi:10.3762/bjnano.12.23

• aggregation of NPs was observed in the RPMI medium over the exposure time (24 h). A dose-dependent relationship between PBMC uptake and Ag concentration was detected for both AgNP and AgNO3 treatment. There was approximately a two-fold increase in cellular Ag uptake in the AgNO3 vs the NP treatment

• images do not show any evidence of aggregation of NPs. Figure 1b and Figure 1d show a skewed distribution and a greater polydispersity of PVP-AgNPs in RPMI medium after 24 h of exposure. As a comparison, the extinction spectra of PVP-AgNPs at concentrations of 100, 500 and 1000 µg·L−1 in RPMI medium

• of NPs are related to Ostwald ripening of NPs [36], as evidenced in our STEM results. The subsequent reduction in size is explained as further transformations that are dominated by dissolution [36]. UV–vis spectroscopy data suggest some aggregation and possible shape changes after reprecipitation at

A review on the green and sustainable synthesis of silver nanoparticles and one-dimensional silver nanostructures

• Sina Kaabipour and
• Shohreh Hemmati

Beilstein J. Nanotechnol. 2021, 12, 102–136, doi:10.3762/bjnano.12.9

• ” synthesis method. These techniques are usually accompanied by the addition of stabilizers to provide stability, prevent aggregation, control morphology, and provide physiologically compatible properties [140][141][142]. Chemical methods were previously used to produce silver nanoparticles including sol–gel

Effect of different silica coatings on the toxicity of upconversion nanoparticles on RAW 264.7 macrophage cells

• Cynthia Kembuan,
• Helena Oliveira and
• Christina Graf

Beilstein J. Nanotechnol. 2021, 12, 35–48, doi:10.3762/bjnano.12.3

• -functionalized particles is small enough for the particles to be internalized via the endocytic uptake [51]. (3-Aminopropyl)trimethoxysilane (APS) was not chosen as the amine ligand due to the increased aggregation of APS-functionalized particles in the cell culture medium [51]. In addition, particles with a

• aggregation of silica nanoparticles that occurred after redispersion in buffered solution and in physiological medium [54]. They reported that various proteins in a medium containing FBS were adsorbed onto the surface of bare SiO2 and amine-functionalized SiO2 nanoparticles, forming a protein corona with a

• nanoparticles more negative; hence, it reduces the stability of positively charged particles [52][58][59]. Although the particles in this work showed increased aggregation in DMEM, they can still be taken up by macrophages, such as RAW 264.7 cells [45]. This is also indicated by the different cytotoxicity

Bio-imaging with the helium-ion microscope: A review

• Matthias Schmidt,
• James M. Byrne and
• Ilari J. Maasilta

Beilstein J. Nanotechnol. 2021, 12, 1–23, doi:10.3762/bjnano.12.1

• that coating, as required for SEM, introduces artefacts such as a granular structure on the cell surfaces and a partial closing of pores, thus highlighting one of the benefits of HIM. Bazou et al. also studied tumour cell-induced platelet aggregation by fluorescence microscopy and HIM. In this study

Self-standing heterostructured NiC_x-NiFe-NC/biochar as a highly efficient cathode for lithium–oxygen batteries

• Shengyu Jing,
• Xu Gong,
• Shan Ji,
• Linhui Jia,
• Bruno G. Pollet,
• Sheng Yan and
• Huagen Liang

Beilstein J. Nanotechnol. 2020, 11, 1809–1821, doi:10.3762/bjnano.11.163

• aggregation during the electrochemical reactions, leading to a relatively high stability. The NiFe-PBA/PP-900 developed in this study suggests that inexpensive and economically viable ORR catalysts for Li–O2 cells are achieved by rationally designing the morphology and tuning the composition of the catalysts

PEG/PEI-functionalized single-walled carbon nanotubes as delivery carriers for doxorubicin: synthesis, characterization, and in vitro evaluation

• Shuoye Yang,
• Zhenwei Wang,
• Yahong Ping,
• Yuying Miao,
• Yongmei Xiao,
• Lingbo Qu,
• Lu Zhang,
• Yuansen Hu and
• Jinshui Wang

Beilstein J. Nanotechnol. 2020, 11, 1728–1741, doi:10.3762/bjnano.11.155

• efficaciously traverse biological barriers [11][12][13]. Despite a series of advantages, the practical application of CNTs has been restricted by a number of drawbacks, such as high hydrophobicity and rapid aggregation in aqueous media, which are associated with cytotoxicity and other harmful cellular effects

• [14][15][16][17][18]. Numerous attempts and efforts have been devoted to improve the dispersibility in water and to reduce the aggregation of CNTs [19][20][21]. The most commonly used approach is noncovalent coating with hydrophilic carboxylic acid groups by oxidizing acid treatment [22][23][24

• PEG and PEI. The main intrinsic drawbacks of SWCNTs are the strong hydrophobicity and easy aggregation in aqueous media [9]. The raw SWCNTs are purified with concentrated acid to obtain carboxylated carbon nanotubes (CNTs-COOH), which significantly improves their water solubility [35][36]. NHS-PEG

Cardiomyocyte uptake mechanism of a hydroxyapatite nanoparticle mediated gene delivery system

• Hiroaki Komuro,
• Masahiro Yamazoe,
• Kosuke Nozaki,
• Akiko Nagai and
• Tetsuo Sasano

Beilstein J. Nanotechnol. 2020, 11, 1685–1692, doi:10.3762/bjnano.11.150

• advantages in using CaP for gene delivery, the transfection efficiency of CaP/DNA is relatively low according to various preparation parameters [10]. In particular, particle aggregation needs to be improved in order to reduce cellular uptake through the endocytic pathway. Hydroxyapatite (HAp, Ca10(PO4)6(OH)2

• are still many limitations, such as low transfection efficiency and reproducibility, that must be overcome for these methods to be successfully used in clinical applications. We were able to successfully produce HAp nanoparticles with less aggregation using the W/O emulsion method, as shown in a