High-resolution electrical and chemical characterization of nm-scale organic and inorganic devices

• Pierre Eyben

Beilstein J. Nanotechnol. 2013, 4, 318–319, doi:10.3762/bjnano.4.35

• , electrochromic devices, biosensors, photodiodes, photovoltaic cells, etc.) have been developed, demonstrating the strong potential of these materials. However, the advent of commercial applications often requires important breakthroughs towards more efficient and stable organic photovoltaic devices. This implies

Functionalization of vertically aligned carbon nanotubes

• Eloise Van Hooijdonk,
• Carla Bittencourt,
• Rony Snyders and
• Jean-François Colomer

Beilstein J. Nanotechnol. 2013, 4, 129–152, doi:10.3762/bjnano.4.14

Assessing the plasmonics of gold nano-triangles with higher order laser modes

• Laura E. Hennemann,
• Andreas Kolloch,
• Andreas Kern,
• Josip Mihaljevic,
• Johannes Boneberg,
• Paul Leiderer,
• Alfred J. Meixner and
• Dai Zhang

Beilstein J. Nanotechnol. 2012, 3, 674–683, doi:10.3762/bjnano.3.77

• patterns on glass as suitable SERS substrates. Since Fischer patterns can easily, cheaply and reproducibly be fabricated on large areas, we advocate that they be used as effective substrates for biosensors based on plasmonic near-field enhanced spectroscopy. Focusing higher order laser modes with a

Directed deposition of silicon nanowires using neopentasilane as precursor and gold as catalyst

• Britta Kämpken,
• Verena Wulf,
• Norbert Auner,
• Marcel Winhold,
• Michael Huth,
• Daniel Rhinow and
• Andreas Terfort

Beilstein J. Nanotechnol. 2012, 3, 535–545, doi:10.3762/bjnano.3.62

• biosensors [3] and chemical sensors [4], nanoelectronics [5], photonics [6] and photovoltaics [7]. In this context, it is important to be able to control parameters such as the diameter and length of the nanowires, as well as their localization [8]. Various techniques have been used in order to produce

FTIR nanobiosensors for Escherichia coli detection

• Stefania Mura,
• Gianfranco Greppi,
• Maria Laura Marongiu,
• Pier Paolo Roggero,
• Sandeep P. Ravindranath,
• Lisa J. Mauer,
• Nicoletta Schibeci,
• Francesco Perria,
• Massimo Piccinini,
• Plinio Innocenzi and
• Joseph Irudayaraj

Beilstein J. Nanotechnol. 2012, 3, 485–492, doi:10.3762/bjnano.3.55

• absorption properties monitored. The film-based biosensors showed a detection limit for E. coli of 1 × 102 CFU/mL, constituting a simple and selective method for the effective screening of water samples. Keywords: biosensors; E. coli; FTIR spectroscopy; foodborne pathogens; nanomaterials; Introduction

• , different optical biosensors were created for rapid detection of pathogenic bacteria, using fluorescence or surface plasmon resonance (SPR) because of their sensitivity [22][23]. For fluorescence analysis, antibodies (Ab) are conjugated with fluorescent compounds and used in combination with classical

• techniques (ELISA, PCR). With these biosensors overnight culture is required, leading to a long time for the analysis, while SPR is a powerful and complex technique, which unfortunately requires specialized staff, and costly and large equipment [24][25]. To overcome these limitations the aim of the present

Fabrication of multi-parametric platforms based on nanocone arrays for determination of cellular response

• Lindarti Purwaningsih,
• Tobias Schoen,
• Tobias Wolfram,
• Claudia Pacholski and
• Joachim P. Spatz

Beilstein J. Nanotechnol. 2011, 2, 545–551, doi:10.3762/bjnano.2.58

• materials are still required in order to control the interaction between cells and materials, and which can find applications in the fields of tissue engineering, implants, cell-based biosensors, and basic cell biology [21]. In this work, a multiparametric platform for the determination of cellular response

Tip-enhanced Raman spectroscopic imaging of patterned thiol monolayers

• Johannes Stadler,
• Thomas Schmid,
• Lothar Opilik,
• Phillip Kuhn,
• Petra S. Dittrich and
• Renato Zenobi

Beilstein J. Nanotechnol. 2011, 2, 509–515, doi:10.3762/bjnano.2.55

• surfaces or certain surface areas. Here, selected areas on a gold surface were modified by a thiol and, in a second step, the remaining substrate was covered by a secondary thiol film. This type of surface can act as a basis for biosensors [12][13]. To produce patterned SAM structures on a gold surface

Towards multiple readout application of plasmonic arrays

• Dana Cialla,
• Karina Weber,
• René Böhme,
• Uwe Hübner,
• Henrik Schneidewind,
• Matthias Zeisberger,
• Roland Mattheis,
• Robert Möller and
• Jürgen Popp

Beilstein J. Nanotechnol. 2011, 2, 501–508, doi:10.3762/bjnano.2.54

• reporter molecules. This work contributes to the development of the more flexible usage of different optical detection schemes on the same chip surface. Results and Discussion The work presented in the following reports on the design and application of biosensors based on periodically patterned plasmonic

Characterization of protein adsorption onto FePt nanoparticles using dual-focus fluorescence correlation spectroscopy

• Pauline Maffre,
• Karin Nienhaus,
• Faheem Amin,
• Wolfgang J. Parak and
• G. Ulrich Nienhaus

Beilstein J. Nanotechnol. 2011, 2, 374–383, doi:10.3762/bjnano.2.43

• issue for various fields including biotechnology (e.g., biosensors, bioanalytics) and biomedical devices (e.g., implants and catheters). To be able to control the biological effects of NPs, such as prevention of uptake or targeted delivery to specific cells or tissues, it is of utmost importance to

Magnetic nanoparticles for biomedical NMR-based diagnostics

• Huilin Shao,
• Tae-Jong Yoon,
• Monty Liong,
• Ralph Weissleder and
• Hakho Lee

Beilstein J. Nanotechnol. 2010, 1, 142–154, doi:10.3762/bjnano.1.17

• more effective magnetic nanoparticle biosensors, DMR detection limits for various target moieties have been considerably improved over the last few years. Already, a library of magnetic nanoparticles has been developed, in which a wide range of targets, including DNA/mRNA, proteins, small molecules

• , however, are faster and simpler since the analytical signal is generated from the entire sample volume. By developing optimized MNPs, DMR detection sensitivities for various target moieties have been considerably improved. To date, numerous magnetic biosensors have been designed to identify and quantify a

• bovine serum albumin (BSA) protein as a control did not elicit any change in T2 (Figure 5b). More recently, MRSw biosensors, capable of detecting soluble tumor biomarker proteins (such as CA-125, VEGF, and α-fetoprotein) were described, and used for parallel detection of multiple markers in blood samples

Electrochemical behavior of dye-linked L-proline dehydrogenase on glassy carbon electrodes modified by multi-walled carbon nanotubes

• Haitao Zheng,
• Leyi Lin,
• Yosuke Okezaki,
• Ryushi Kawakami,
• Haruhiko Sakuraba,
• Toshihisa Ohshima,
• Keiichi Takagi and
• Shin-ichiro Suye

Beilstein J. Nanotechnol. 2010, 1, 135–141, doi:10.3762/bjnano.1.16

• require considerable time for analysis. In recent years, researchers have paid much more attention to the construction of electrochemical enzyme biosensors for the analysis of amino acids [5][6][7], and several electrochemical biosensing systems for L-proline and D-proline determination have been reported

• [8][9]. In the construction of enzyme biosensors, efficient communication between the active site of enzyme molecule and the electrode surface is one of the most important factors for sensor performance. As the protein shell always prevents the direct electron transfer from the active site of the

• enzyme, specific immobilization strategies, including electron mediators, should be considered [10][11][12]. In the last decade, the use of nano materials, especially carbon nanotubes (CNTs), in the construction of enzyme biosensors has received considerable attention. Because of their excellent