Recent advances in photothermal nanomaterials for ophthalmic applications

• Jiayuan Zhuang,
• Linhui Jia,
• Chenghao Li,
• Rui Yang,
• Jiapeng Wang,
• Wen-an Wang,
• Heng Zhou and
• Xiangxia Luo

Beilstein J. Nanotechnol. 2025, 16, 195–215, doi:10.3762/bjnano.16.16

• ), fluorescence imaging (FI), scanning laser ophthalmoscopy (SLO), and fundus photography have significantly changed the diagnosis and monitoring of ocular diseases [174][175][176]. OCT is the most prevalent ophthalmic imaging technique, providing high-resolution and high-sensitivity imaging; however, the test

Modeling and simulation of carbon-nanocomposite-based gas sensors

• Roopa Hegde,
• Punya Prabha V,
• Shipra Upadhyay and
• Krishna S B

Beilstein J. Nanotechnol. 2025, 16, 90–96, doi:10.3762/bjnano.16.9

• showed high sensitivity towards strong electron-withdrawing molecules for NO2 gas detection [10]. To simulate gas adsorption in COMSOL Multiphysics for a gas sensor, several adsorption models can be employed depending on the physical and chemical behavior of the sensor. Commonly used models include the

Direct electron beam writing of silver using a β-diketonate precursor: first insights

• Katja Höflich,
• Krzysztof Maćkosz,
• Chinmai S. Jureddy,
• Aleksei Tsarapkin and
• Ivo Utke

Beilstein J. Nanotechnol. 2024, 15, 1117–1124, doi:10.3762/bjnano.15.90

• very high sensitivity with respect to electron beam impact are observed during dissociation with the weakly focused beam of a thermal electron emitter. However, for the first time, sufficient vertical growth rates in combination with high fidelity were achieved for a tightly focused electron beam

Unveiling the potential of alginate-based nanomaterials in sensing technology and smart delivery applications

• Shakhzodjon Uzokboev,
• Khojimukhammad Akhmadbekov,
• Ra’no Nuritdinova,
• Salah M. Tawfik and
• Yong-Ill Lee

Beilstein J. Nanotechnol. 2024, 15, 1077–1104, doi:10.3762/bjnano.15.88

• , Cairo 11727, Egypt Anastro Laboratory, Institute of Basic Science, Changwon National University, Changwon 51140, Republic of Korea 10.3762/bjnano.15.88 Abstract Sensors are applied to many fields nowadays because of their high sensitivity, low cost, time-saving, user-friendly, and excellent selectivity

• nanoparticles for metal sensing has gained significant interest among researchers and scientists [106]. Nanoparticles offer several advantages for metal sensing, including high sensitivity, real-time detection, and ease of sample processing [106][107][108]. Alginate-based nanoparticles have emerged as a

• kilohertz. Another alginate-based humidity sensor is carbonized lignin-loaded sodium alginate (CL/SA). The CL/SA composite film provided extremely high sensitivity, low hysteresis, and consistent repeatability throughout a wide relative humidity range of 11–97%. Furthermore, the CL/SA sensor allowed for

Signal generation in dynamic interferometric displacement detection

• Knarik Khachatryan,
• Simon Anter,
• Michael Reichling and
• Alexander von Schmidsfeld

Beilstein J. Nanotechnol. 2024, 15, 1070–1076, doi:10.3762/bjnano.15.87

• a reflectivity of Rf = 0.04. The fourth end of the 3 dB coupler is connected to the detector, which is a photoreceiver (model HBPR-200M-30K-SI-FC, FEMTO Messtechnik, Berlin, Germany) converting the incoming light power into a voltage signal. The photoreceiver allows for high-sensitivity low-noise

Recent progress on field-effect transistor-based biosensors: device perspective

• Billel Smaani,
• Fares Nafa,
• Mohamed Salah Benlatrech,
• Ismahan Mahdi,
• Hamza Akroum,
• Mohamed walid Azizi,
• Khaled Harrar and
• Sayan Kanungo

Beilstein J. Nanotechnol. 2024, 15, 977–994, doi:10.3762/bjnano.15.80

• from researchers due to their desirable properties and advantages, including low cost, label-free operation, high sensitivity, robustness, low power consumption, and a straightforward fabrication process based on CMOS technology [47][48]. A field-effect transistor-based biosensor comprises a

• (≈108) and increased sensing speed through the extended cavity in the oxide–source region of the proposed biosensor structure. Furthermore, the fabrication of a silicon NW TFET-based biosensor has been reported by Gao et al. [84], targeting high sensitivity, versatility, and reliability for point-of

• -end biosensing parts are made using gold electrode material and manufactured by a lithography process, liftoff technique, and metal evaporation process. It has been indicated that the proposed EG FET-based biosensors exhibit super selectivity and high sensitivity for a reliable detection of uric acid

Exploring surface charge dynamics: implications for AFM height measurements in 2D materials

• Mario Navarro-Rodriguez,
• Andres M. Somoza and
• Elisa Palacios-Lidon

Beilstein J. Nanotechnol. 2024, 15, 767–780, doi:10.3762/bjnano.15.64

• ], and slight changes in the reduction degree may vary the conductivity by many orders of magnitude [69], which would explain the high sensitivity of the measurements to the local reduction degree within one partially reduced rGO flake. To account for Joule dissipation, different models have been derived

AFM-IR investigation of thin PECVD SiO_x films on a polypropylene substrate in the surface-sensitive mode

• Hendrik Müller,
• Hartmut Stadler,
• Teresa de los Arcos,
• Adrian Keller and
• Guido Grundmeier

Beilstein J. Nanotechnol. 2024, 15, 603–611, doi:10.3762/bjnano.15.51

• technique. The signal of the 5 nm thin SiOx layer has increased enormously. These measurements show the high sensitivity of this technique by detecting even 5 nm ultra-thin coatings on top of a polymeric substrate. This effect could have been supported by the choice of substrate material as shown in the

Stiffness calibration of qPlus sensors at low temperature through thermal noise measurements

• Laurent Nony,
• Sylvain Clair,
• Daniel Uehli,
• Aitziber Herrero,
• Jean-Marc Themlin,
• Andrea Campos,
• Franck Para,
• Alessandro Pioda and
• Christian Loppacher

Beilstein J. Nanotechnol. 2024, 15, 580–602, doi:10.3762/bjnano.15.50

• possible to quantify the interatomic interaction forces that develop between the tip and the surface acquired in spectroscopic data cube modes [7][8] with both high sensitivity and high spatial resolution. Recently, the force sensitivity has been pushed forward, and forces as low as 100 fN have been

Potential of a deep eutectic solvent in silver nanoparticle fabrication for antibiotic residue detection

• Le Hong Tho,
• Bui Xuan Khuyen,
• Ngoc Xuan Dat Mai and
• Nhu Hoa Thi Tran

Beilstein J. Nanotechnol. 2024, 15, 426–434, doi:10.3762/bjnano.15.38

• [2], the ability of real-time measurements [3], extremely high sensitivity [4], remarkable selectivity [5], and tremendous versatility [4][6][7]. Many scholars have taken advantage of these properties in cancer diagnosis [8], detection of hazardous chemicals [9], tracing of microorganisms [7][10][11

• -DES substrate. Besides the high sensitivity, the sensor exhibits also uniformity of the coating, consistency in SERS signals, and good selectivity. Overall, Ag NPs-DES is a promising candidate for SERS-based biosensor applications. This work hopefully provides useful information about the potential of

Ultrasensitive and ultrastretchable metal crack strain sensor based on helical polydimethylsiloxane

• Shangbi Chen,
• Dewen Liu,
• Weiwei Chen,
• Huajiang Chen,
• Jiawei Li and
• Jinfang Wang

Beilstein J. Nanotechnol. 2024, 15, 270–278, doi:10.3762/bjnano.15.25

• platform for constructing strain sensors with both high sensitivity and stretchability, showing a far-reaching significance and influence for developing next-generation practically applicable soft electronics. Keywords: crack sensors; helical structure; polydimethylsiloxane (PDMS); ultrahigh sensitivity

• sensor that exhibits both high sensitivity and a wide range of strain through the combined integration of a cracked thin metal and a 3D helical substrate. The fabrication process involves depositing a Au thin film onto a PDMS substrate with helical structure, followed by pre-stretching to induce

• approach through the development of a strain sensor based on cracks with high stretchability, aiming to address the limitations of sensing range in soft electronic devices. Furthermore, this research provides a versatile framework for constructing strain sensors that exhibit both high sensitivity and

Design, fabrication, and characterization of kinetic-inductive force sensors for scanning probe applications

• August K. Roos,
• Ermes Scarano,
• Elisabet K. Arvidsson,
• Erik Holmgren and
• David B. Haviland

Beilstein J. Nanotechnol. 2024, 15, 242–255, doi:10.3762/bjnano.15.23

• electromechanical coupling. The coupling of the microwave resonator to a transmission line is also an important design consideration. Our primary goal is high sensitivity to tip–surface forces, given the constraints of the AFM application. If the detector is limited by thermal noise, the sensitivity is given by the

New application of bimetallic Ag/Pt nanoplates in a colorimetric biosensor for specific detection of E. coli in water

• Azam Bagheri Pebdeni,
• Mohammad N. AL-Baiati and
• Morteza Hosseini

Beilstein J. Nanotechnol. 2024, 15, 95–103, doi:10.3762/bjnano.15.9

• %. The developed assay should serve as a general platform for detecting other pathogenic bacteria which affect water and food quality. The proposed E. coli detection strategy has appealing characteristics such as high sensitivity, simple operation, short testing time, and low cost. Keywords: aptamer

• . Colorimetric biosensors have become popular in analytical applications due to their high sensitivity, convenience, and ease of signal readout [7][8]. These biosensors have been extensively utilized in pathogen identification, primarily because of their ability to rapidly display results in visible color [9][10

• previously published E. coli detection methods. The findings were compared to those of previous specified situations, proving that this technique gives an increased dynamic range and appropriate LOD. This biosensor offers several advantages such as quick reaction, high sensitivity, ease of use, low cost, and

Measurements of dichroic bow-tie antenna arrays with integrated cold-electron bolometers using YBCO oscillators

• Leonid S. Revin,
• Dmitry A. Pimanov,
• Alexander V. Chiginev,
• Anton V. Blagodatkin,
• Viktor O. Zbrozhek,
• Andrey V. Samartsev,
• Anastasia N. Orlova,
• Dmitry V. Masterov,
• Alexey E. Parafin,
• Victoria Yu. Safonova,
• Anna V. Gordeeva,
• Andrey L. Pankratov,
• Leonid S. Kuzmin,
• Anatolie S. Sidorenko,
• Silvia Masi and
• Paolo de Bernardis

Beilstein J. Nanotechnol. 2024, 15, 26–36, doi:10.3762/bjnano.15.3

• BICEP Array, LSPE, LiteBIRD, QUBIC, Simons Observatory, and AliCPT. As a direct radiation detector, we use cold-electron bolometers, which have high sensitivity and a wide operating frequency range, as well as immunity to spurious cosmic rays. Their other advantages are the compact size of the order of

• efficiency. As a direct radiation detector, we consider using the cold-electron bolometer (CEB) concept [11][12]. These bolometers have high sensitivity with background-limited operation [13][14][15], a broad operating frequency range, as well as immunity to spurious cosmic rays [16]. Since CEB sizes are of

Dual-heterodyne Kelvin probe force microscopy

• Benjamin Grévin,
• Fatima Husainy,
• Dmitry Aldakov and
• Cyril Aumaître

Beilstein J. Nanotechnol. 2023, 14, 1068–1084, doi:10.3762/bjnano.14.88

• -KPFM, thanks to the signal enhancement provided by the second eigenmode, can image weak SPV signals that would otherwise be barely detectable. To illustrate the capabilities of DHe-KPFM in terms of high sensitivity, we have chosen as a model system an optoelectronic interface that can be obtained by

Antibody-conjugated nanoparticles for target-specific drug delivery of chemotherapeutics

• Mamta Kumari,
• Amitabha Acharya and
• Praveen Thaggikuppe Krishnamurthy

Beilstein J. Nanotechnol. 2023, 14, 912–926, doi:10.3762/bjnano.14.75

• effect makes the NPs very selective and provides a high sensitivity for binding on the target surface. Multicomponent effect of protein corona on antibody-conjugated NPs The small hydrodynamic diameter and unique structure of NPs offer increased adsorption and catalytic efficiency. The NP surface

Silver-based SERS substrates fabricated using a 3D printed microfluidic device

• Phommachith Sonexai,
• Minh Van Nguyen,
• Bui The Huy and
• Yong-Ill Lee

Beilstein J. Nanotechnol. 2023, 14, 793–803, doi:10.3762/bjnano.14.65

• detection of harmful chemicals in the environment and for food safety is a crucial requirement. While traditional techniques such as GC–MS and HPLC provide high sensitivity, they are expensive, time-consuming, and require skilled labor. Surface-enhanced Raman spectroscopy (SERS) is a powerful analytical

Metal-organic framework-based nanomaterials as opto-electrochemical sensors for the detection of antibiotics and hormones: A review

• Akeem Adeyemi Oladipo,
• Saba Derakhshan Oskouei and
• Mustafa Gazi

Beilstein J. Nanotechnol. 2023, 14, 631–673, doi:10.3762/bjnano.14.52

• ) sensors have been developed for antibiotic and hormone detection analyses to address the limitations of the standard analytical methods. These sensors’ advantages include high sensitivity, low cost, rapid analysis time, simplified operation without the need for complicated and expensive instrumentation

• from the optical signals. In recent years, interest in optical methods of hormone and antibiotic detection has grown due to their rapid response times, simplicity of use, and high sensitivity [32][33][34][35][36][37][38]. In contrast to other techniques such as colourimetry and surface plasmon

• antibiotic’s internal filter effect and confirms that FRET does not occur. A multicolour fluorescent tetracycline nanosensor (Figure 8) with an ultra-high sensitivity and a detection limit of 7.1 nM in real samples (river and lake water, honey, and milk) was reported by Zhang et al. [52] in another study. The

High–low Kelvin probe force spectroscopy for measuring the interface state density

• Ryo Izumi,
• Masato Miyazaki,
• Yan Jun Li and
• Yasuhiro Sugawara

Beilstein J. Nanotechnol. 2023, 14, 175–189, doi:10.3762/bjnano.14.18

• advantages, namely high sensitivity to the electrostatic force gradient, high detection sensitivity using a cantilever with a weak spring constant at the first resonance, ease of implementation in adding FM-AFM, and no need to enhance the bandwidth of the cantilever deflection sensor. FM-KPFM is used to

Characterisation of a micrometer-scale active plasmonic element by means of complementary computational and experimental methods

• Ciarán Barron,
• Giulia Di Fazio,
• Samuel Kenny,
• Silas O’Toole,
• Robin O’Reilly and
• Dominic Zerulla

Beilstein J. Nanotechnol. 2023, 14, 110–122, doi:10.3762/bjnano.14.12

• subsequent paper. At this stage, experiments with active elements of different sizes reveal that the ratio between heated and non-heated surface illuminated by the laser beam influences the intensity of this effect. The ability to observe these details demonstrates the high sensitivity of this technique to

Structural studies and selected physical investigations of LiCoO₂ obtained by combustion synthesis

• Monika Michalska,
• Paweł Ławniczak,
• Tomasz Strachowski,
• Adam Ostrowski and
• Waldemar Bednarski

Beilstein J. Nanotechnol. 2022, 13, 1473–1482, doi:10.3762/bjnano.13.121

• resonance (EPR) experiments were performed using an X-band ELEXSYS E500 (Bruker, Germany) spectrometer. The samples were placed in a Super High Sensitivity Probehead (Bruker, Germany) cavity and in a cryostat where the temperature was determined and stabilized using an Oxford temperature controller ITC503S

Rapid and sensitive detection of box turtles using an electrochemical DNA biosensor based on a gold/graphene nanocomposite

• Abu Hashem,
• M. A. Motalib Hossain,
• Ab Rahman Marlinda,
• Mohammad Al Mamun,
• Khanom Simarani and
• Mohd Rafie Johan

Beilstein J. Nanotechnol. 2022, 13, 1458–1472, doi:10.3762/bjnano.13.120

• biosensor exhibited high sensitivity, excellent selectivity, and good stability with the desired detection limit. It might have a promising future for detecting box turtle adulteration in food products and solving the problem of point-of-care application after commercial adaptation. However, attaining good

Double-layer symmetric gratings with bound states in the continuum for dual-band high-Q optical sensing

• Chaoying Shi,
• Jinhua Hu,
• Xiuhong Liu,
• Junfang Liang,
• Jijun Zhao,
• Haiyan Han and
• Qiaofen Zhu

Beilstein J. Nanotechnol. 2022, 13, 1408–1417, doi:10.3762/bjnano.13.116

• show that the values of α and h need to be decreased as much as possible to obtain high sensitivity and FOM of mode 1. The results were slightly different from those of mode 2, where one of the most sensitive regions exists, as shown in Figure 8b. This is may be due to the insignificant phase

• difference in the DLSG structure considered here [58]. Therefore, we can optimize the sensing performance by controlling the structural parameters, such as α and h, which are essentially the result of perturbing the artificial BIC and FP-BIC. The high sensitivity and FOM can be obtained thanks to the nearly

Studies of probe tip materials by atomic force microscopy: a review

• Ke Xu and
• Yuzhe Liu

Beilstein J. Nanotechnol. 2022, 13, 1256–1267, doi:10.3762/bjnano.13.104

• addition, the method was also used for the determination of glyphosate in tap water samples with good recovery results. The assay has the advantages of high sensitivity and good selectivity. Compared to the above-proposed metal nanoclusters, gold-based bimetallic nanoclusters have the advantages of metal

• and conductive materials at the nanoscale. Slattery et al. [46] describe the use of Pt/Ir conductive tips modified with single-walled carbon nanotubes (SWCNTs), a type of tip suitable for use in conductive imaging mode with high-sensitivity current acquisition AFM, which can also be applied to worn

• to the reaction system. Therefore, the method is suitable for the field detection of antibiotics in liquid foods. More importantly, the proposed homogeneity method has been successfully applied to actual milk samples. This novel homogeneity method with high sensitivity and selectivity is a powerful

A super-oscillatory step-zoom metalens for visible light

• Yi Zhou,
• Chao Yan,
• Peng Tian,
• Zhu Li,
• Yu He,
• Bin Fan,
• Zhiyong Wang,
• Yao Deng and
• Dongliang Tang

Beilstein J. Nanotechnol. 2022, 13, 1220–1227, doi:10.3762/bjnano.13.101

• designed super-oscillatory spots [9][10]. Nevertheless, the low efficiency may be tolerable for some specific applications, such as observing target objects with high illumination intensity in microscopic systems. High-sensitivity detectors and long exposure time would be also advantageous. Conclusion In