Polymer lipid hybrid nanoparticles for phytochemical delivery: challenges, progress, and future prospects

• Iqra Rahat,
• Pooja Yadav,
• Aditi Singhal,
• Mohammad Fareed,
• Jaganathan Raja Purushothaman,
• Mohammed Aslam,
• Raju Balaji,
• Sonali Patil-Shinde and
• Md. Rizwanullah

Beilstein J. Nanotechnol. 2024, 15, 1473–1497, doi:10.3762/bjnano.15.118

• classification, IQN belongs to class II. It shows limited solubility in the GI fluids and very low bioavailability after oral administration [119]. Wang et al. fabricated IQN-encapsulated zein phosphatidylcholine hybrid nanoparticles (IQN-PLHNPs) for improved oral efficacy against triple-negative breast cancer

Curcumin-loaded albumin submicron particles with potential as a cancer therapy: an in vitro study

• Nittiya Suwannasom,
• Netsai Sriaksorn,
• Chutamas Thepmalee,
• Krissana Khoothiam,
• Ausanai Prapan,
• Hans Bäumler and
• Chonthida Thephinlap

Beilstein J. Nanotechnol. 2023, 14, 1127–1140, doi:10.3762/bjnano.14.93

• stability and solubility [9]. The complexation occurs mainly through hydrophobic interactions in protein cavities [10][11]. In a recent study, zein nanoparticles loaded with CUR have been studied for their potential in treating brain tumors, and the results have demonstrated a reduction in the proliferation

• silk core–shell nanoparticles show high cytotoxicity and cellular uptake regarding breast cancer cells [14]. However, the effectiveness of zein nanoparticles as a delivery vehicle is limited by their poor stability, as they tend to aggregate when suspended in water [15]. Lyophilizing the particles

Biomimetic chitosan with biocomposite nanomaterials for bone tissue repair and regeneration

• Se-Kwon Kim,
• Sesha Subramanian Murugan,
• Pandurang Appana Dalavi,
• Sebanti Gupta,
• Sukumaran Anil,
• Gi Hun Seong and
• Jayachandran Venkatesan

Beilstein J. Nanotechnol. 2022, 13, 1051–1067, doi:10.3762/bjnano.13.92

• , polyhydroxyethylmethacrylate, and polyethylene glycol were used in composite preparation for bone tissue engineering applications [10]. To create a fibrous scaffold for bone tissue regeneration, zein and chitosan were combined with polyurethane and functionalized multiwalled carbon nanotubes. The developed scaffolds have

The role of deep eutectic solvents and carrageenan in synthesizing biocompatible anisotropic metal nanoparticles

• Nabojit Das,
• Akash Kumar and
• Raja Gopal Rayavarapu

Beilstein J. Nanotechnol. 2021, 12, 924–938, doi:10.3762/bjnano.12.69

• λ-carrageenan polysaccharides of different concentrations [113]. The particle size, morphology, and stability were predominantly determined by the concentration and the gelation properties of the used carrageenan. Another study involved stabilizing zein nanoparticles using ι-carrageenan to prevent

BergaCare SmartLipids: commercial lipophilic active concentrates for improved performance of dermal products

• Florence Olechowski,
• Rainer H. Müller and
• Sung Min Pyo

Beilstein J. Nanotechnol. 2019, 10, 2152–2162, doi:10.3762/bjnano.10.208

• carrier systems, but only with limited increase in stability. Stabilities reported were 20% after ten days in liposomes [18], 40% after 24 h in a nanoemulsion [19], 50% after 24 h in zein colloidal particles [19] and 60% after one month in a nanoemulsion stabilized by silica [20]. A screening was

Layered double hydroxide/sepiolite hybrid nanoarchitectures for the controlled release of herbicides

• Ediana Paula Rebitski,
• Margarita Darder and
• Pilar Aranda

Beilstein J. Nanotechnol. 2019, 10, 1679–1690, doi:10.3762/bjnano.10.163

• for agricultural applications. In order to achieve a more controlled release of the herbicide and to act for several days on the surface of the soil, the hybrid nanoarchitectures were encapsulated in a biopolymer matrix of alginate/zein and shaped into spheres. In in vitro tests carried out in

• in vitro tests of MCPA release, confirming the improvement of retention properties. For a better control in the MCPA release, the hybrid nanoarchitectures were also combined with mixtures of alginate–zein biopolymers [36] to improve the retention properties. Results and Discussion MCPA-LDH/sepiolite

• ], a biopolymer mixture of alginate and zein incorporating the MCPAie-LDH hybrid prepared by ion exchange was able to reduce the initial release of MCPA by approximately 10–15% in the first 8 h. In the current work, the MCPA-LDH/Sep0.5:1_60C nanoarchitecture was selected, as it releases 100% of the

Effective intercalation of zein into Na-montmorillonite: role of the protein components and use of the developed biointerfaces

• Ana C. S. Alcântara,
• Margarita Darder,
• Pilar Aranda and
• Eduardo Ruiz-Hitzky

Beilstein J. Nanotechnol. 2016, 7, 1772–1782, doi:10.3762/bjnano.7.170

• /bjnano.7.170 Abstract Biohybrid materials based on the intercalation of zein, the major storage protein in corn, into sodium-exchanged montmorillonite were prepared following two synthesis strategies. The first one made use of zein dissolved in 80% (v/v) ethanol/water solution, the usual solvent for this

• protein, while the second method is new and uses a sequential process that implies the previous separation of zein components in absolute ethanol. This treatment of zein with ethanol renders a soluble yellow phase and an agglomerate of insoluble components, which are able to intercalate the layered

• ; biointerfaces; bionanocomposites; montmorillonite; zein; Introduction Organic–inorganic hybrids are composed of organic and inorganic units that interact at the molecular scale, and the characteristics of these subunits determine a broad range of properties of the hybrid relevant for many applications [1