Discovery of practical production processes for arylsulfur pentafluorides and their higher homologues, bis- and tris(sulfur pentafluorides): Beginning of a new era of “super-trifluoromethyl” arene chemistry and its industry

• Teruo Umemoto,
• Lloyd M. Garrick and
• Norimichi Saito

Beilstein J. Org. Chem. 2012, 8, 461–471, doi:10.3762/bjoc.8.53

• to the previous methods using AgF2, F2, or XeF2, or multiple-step methods starting from SF5Br or SF5Cl, in terms of cost, applicability, and scalability of production, the processes developed here can be used as the first practical and economical methods for the production of many kinds of arylsulfur

Scaling up of continuous-flow, microwave-assisted, organic reactions by varying the size of Pd-functionalized catalytic monoliths

• Ping He,
• Stephen J. Haswell,
• Paul D. I. Fletcher,
• Stephen M. Kelly and
• Andrew Mansfield

Beilstein J. Org. Chem. 2011, 7, 1150–1157, doi:10.3762/bjoc.7.133

• maintaining the intrinsic benefits of the reaction geometry offered when using microreactor methodology. In this work we report a simple and effective approach for achieving volumetric scalability in a flow reaction system through the use of Pd-supported silica-based monolithic reactors coupled with microwave