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Search for "structural features" in Full Text gives 209 result(s) in Beilstein Journal of Organic Chemistry. Showing first 200.

Art, auto-mechanics, and supramolecular chemistry. A merging of hobbies and career

  • Eric V. Anslyn

Beilstein J. Org. Chem. 2016, 12, 362–376, doi:10.3762/bjoc.12.40

Graphical Abstract
  • trielaidin over trielroselaidin (differing only by double bond position in each fatty acid chain, Figure 11) and a second synthetic receptor that did the opposite. Thus, if successful, the demonstration of a differential sensing approach that could classify glycerides, determine their structural features
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Published 26 Feb 2016

Natural products from microbes associated with insects

  • Christine Beemelmanns,
  • Huijuan Guo,
  • Maja Rischer and
  • Michael Poulsen

Beilstein J. Org. Chem. 2016, 12, 314–327, doi:10.3762/bjoc.12.34

Graphical Abstract
  • pharmaceutical properties evaluated, and on compounds with unique structural features. We demonstrate that the exploration of specific microbial–host interactions, in combination with multidisciplinary dereplication processes, has emerged as a successful strategy to identify novel chemical entities and to shed
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Published 19 Feb 2016

Spiro-fused carbohydrate oxazoline ligands: Synthesis and application as enantio-discrimination agents in asymmetric allylic alkylation

  • Jochen Kraft,
  • Martin Golkowski and
  • Thomas Ziegler

Beilstein J. Org. Chem. 2016, 12, 166–171, doi:10.3762/bjoc.12.18

Graphical Abstract
  • with Pd(cod)Cl2 (Figure 1). Single crystal X-ray diffraction of these Pd complexes revealed some interesting structural features in terms of ligand–metal bite angles and shielding of the palladium center by the carbohydrate scaffold from one specific side [17]. For example, we concluded from the
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Published 29 Jan 2016

Inclusion complexes of 2-methoxyestradiol with dimethylated and permethylated β-cyclodextrins: models for cyclodextrin–steroid interaction

  • Mino R. Caira,
  • Susan A. Bourne,
  • Halima Samsodien and
  • Vincent J. Smith

Beilstein J. Org. Chem. 2015, 11, 2616–2630, doi:10.3762/bjoc.11.281

Graphical Abstract
  • host and guest during complexation [1]. Complex units A and B of TRIMEB·2ME, related by a pseudo-translation of ≈b/2, have nearly identical structural features, namely common TRIMEB host conformations and lack of host disorder, apparent twofold disorder of the 2ME methylene group at C6 (site-occupancy
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Published 16 Dec 2015

Organocatalytic and enantioselective Michael reaction between α-nitroesters and nitroalkenes. Syn/anti-selectivity control using catalysts with the same absolute backbone chirality

  • Jose I. Martínez,
  • Uxue Uria,
  • Maria Muñiz,
  • Efraím Reyes,
  • Luisa Carrillo and
  • Jose L. Vicario

Beilstein J. Org. Chem. 2015, 11, 2577–2583, doi:10.3762/bjoc.11.277

Graphical Abstract
  • incorporation of additives or co-catalysts [10][11][12][13], the modification of some structural features of the substrate [14][15], the use of two catalysts that are structurally different to each other and that can also operate independently through a single transition state with minimal matched/mismatched
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Published 14 Dec 2015

Smart molecules for imaging, sensing and health (SMITH)

  • Bradley D. Smith

Beilstein J. Org. Chem. 2015, 11, 2540–2548, doi:10.3762/bjoc.11.274

Graphical Abstract
  • ) Two views of the threaded complex highlighting the structural features controlling the threading kinetics and thermodynamics. Acknowledgements First and foremost, I am extremely grateful to all of the students who have worked in my lab over years, and the names of many are listed in the references
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Published 10 Dec 2015

Synthesis of Xenia diterpenoids and related metabolites isolated from marine organisms

  • Tatjana Huber,
  • Lara Weisheit and
  • Thomas Magauer

Beilstein J. Org. Chem. 2015, 11, 2521–2539, doi:10.3762/bjoc.11.273

Graphical Abstract
  • a large group of structurally diverse secondary metabolites. Among these natural products, Xenia diterpenoids or xenicanes represent a unique family with intriguing structural features and diverse biological activities. Many xenicanes display significant cytotoxic and antibacterial activity and are
  • -related diterpenoids. Additionally, total syntheses of xeniolides and of a crenulatane natural product were illustrated. It has been shown that the rare structural features of Xenia diterpenoids represent an enduring challenge for the total synthesis of these fascinating metabolites. For these reasons
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Published 10 Dec 2015

2-Hetaryl-1,3-tropolones based on five-membered nitrogen heterocycles: synthesis, structure and properties

  • Yury A. Sayapin,
  • Inna O. Tupaeva,
  • Alexandra A. Kolodina,
  • Eugeny A. Gusakov,
  • Vitaly N. Komissarov,
  • Igor V. Dorogan,
  • Nadezhda I. Makarova,
  • Anatoly V. Metelitsa,
  • Valery V. Tkachev,
  • Sergey M. Aldoshin and
  • Vladimir I. Minkin

Beilstein J. Org. Chem. 2015, 11, 2179–2188, doi:10.3762/bjoc.11.236

Graphical Abstract
  • relative the OH counterpart. The calculations reproduce sufficiently well the experimentally determined geometries of compounds 5g and 6e as well as their main structural features such as the very short O···N distances and the folding of the seven-membered rings (see Supporting Information File 1). We have
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Published 12 Nov 2015

Hexacoordinate Ru-based olefin metathesis catalysts with pH-responsive N-heterocyclic carbene (NHC) and N-donor ligands for ROMP reactions in non-aqueous, aqueous and emulsion conditions

  • Shawna L. Balof,
  • K. Owen Nix,
  • Matthew S. Olliff,
  • Sarah E. Roessler,
  • Arpita Saha,
  • Kevin B. Müller,
  • Ulrich Behrens,
  • Edward J. Valente and
  • Hans-Jörg Schanz

Beilstein J. Org. Chem. 2015, 11, 1960–1972, doi:10.3762/bjoc.11.212

Graphical Abstract
  • hydrophilic phosphine ligands [22][23][24][25], NHC ligands [26][27][28][29], N-donor ligands [30], alkylidene moieties [31][32][33] or combinations of these structural features [34][35][36][37]. Another recent development in homogeneous catalysis, and olefin metathesis in particular, have become switchable
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Published 21 Oct 2015

Profluorescent substrates for the screening of olefin metathesis catalysts

  • Raphael Reuter and
  • Thomas R. Ward

Beilstein J. Org. Chem. 2015, 11, 1886–1892, doi:10.3762/bjoc.11.203

Graphical Abstract
  • small volumes, high boiling solvents with different structural features were selected. From the screening, the following features were apparent: Grubbs–Hoveyda and Grela catalysts 1 and 2 perform better for substrate 8 in most solvents. For solvents that contain a carbonyl or carboxyl function (i.e., 2
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Published 12 Oct 2015

Pyridinoacridine alkaloids of marine origin: NMR and MS spectral data, synthesis, biosynthesis and biological activity

  • Louis P. Sandjo,
  • Victor Kuete and
  • Maique W. Biavatti

Beilstein J. Org. Chem. 2015, 11, 1667–1699, doi:10.3762/bjoc.11.183

Graphical Abstract
  • atoms. Fortunately, NMR techniques such as 1,n-ADEQUATE can be used to solve the problem of carbon assignment but the experimental time is long, the sensitivity is poor, and a substantial amount of sample is required. However, pyridoacridines present some structural features that can be used for
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Published 18 Sep 2015

Dicarboxylic esters: Useful tools for the biocatalyzed synthesis of hybrid compounds and polymers

  • Ivan Bassanini,
  • Karl Hult and
  • Sergio Riva

Beilstein J. Org. Chem. 2015, 11, 1583–1595, doi:10.3762/bjoc.11.174

Graphical Abstract
  • ) Regioselective enzymatic acylation of natural products. Natural products are traditionally classified into groups of substances (terpenes, alkaloids, amino acids, lipids, etc), depending on their biosynthetic origin and on their chemical and structural features [19][20][21]. The complex structures of most of
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Published 09 Sep 2015

Why base-catalyzed isomerization of N-propargyl amides yields mostly allenamides rather than ynamides

  • Armando Navarro-Vázquez

Beilstein J. Org. Chem. 2015, 11, 1441–1446, doi:10.3762/bjoc.11.156

Graphical Abstract
  • employing harsh reaction conditions. The outcome of the isomerization process seems to subtlety depend on the structural features of the N-propargyl compound. Similar issues have been observed for carbamates or phosphoramides [8]. In summary, the isomerization process is not yet well understood and, quoting
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Published 18 Aug 2015

Spiro annulation of cage polycycles via Grignard reaction and ring-closing metathesis as key steps

  • Sambasivarao Kotha,
  • Mohammad Saifuddin,
  • Rashid Ali and
  • Gaddamedi Sreevani

Beilstein J. Org. Chem. 2015, 11, 1367–1372, doi:10.3762/bjoc.11.147

Graphical Abstract
  • are interesting targets because of their unusual structural features such as the deformation of the ideal C–C bond angles, high degree of symmetry and the enhanced ring strain etc. [5][6][7][8][9][10][11][12][13][14][15][16][17][18]. The structures of a variety of intricate cage systems, for example
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Published 05 Aug 2015

Selected synthetic strategies to cyclophanes

  • Sambasivarao Kotha,
  • Mukesh E. Shirbhate and
  • Gopalkrushna T. Waghule

Beilstein J. Org. Chem. 2015, 11, 1274–1331, doi:10.3762/bjoc.11.142

Graphical Abstract
  • and nanomaterials is a challenging task. Huang and co-workers [165] have reported a taco complex template method to synthesize a cryptand/paraquat [2]rotaxane and [2]catenane (e.g., 207) by using RCM as a key step. Structural features and interesting bioactivity of the hirsutellones have grabbed the
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Published 29 Jul 2015

New palladium–oxazoline complexes: Synthesis and evaluation of the optical properties and the catalytic power during the oxidation of textile dyes

  • Rym Hassani,
  • Mahjoub Jabli,
  • Yakdhane Kacem,
  • Jérôme Marrot,
  • Damien Prim and
  • Béchir Ben Hassine

Beilstein J. Org. Chem. 2015, 11, 1175–1186, doi:10.3762/bjoc.11.132

Graphical Abstract
  • structural features have been used in diverse reactions [8]. The importance of these ligands lies in the fact that the stereogenic centers are kept in close proximity to the metal and thereby having a strong and direct influence on the stereochemical course of the metal-catalyzed process. Oxazolines possess
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Published 15 Jul 2015

Donor–acceptor type co-crystals of arylthio-substituted tetrathiafulvalenes and fullerenes

  • Xiaofeng Lu,
  • Jibin Sun,
  • Shangxi Zhang,
  • Longfei Ma,
  • Lei Liu,
  • Hui Qi,
  • Yongliang Shao and
  • Xiangfeng Shao

Beilstein J. Org. Chem. 2015, 11, 1043–1051, doi:10.3762/bjoc.11.117

Graphical Abstract
  • co-crystals of fullerene (as the acceptor) and arylthio-substituted tetrathiafulvalene derivatives (Ar-S-TTF, as the donor) were prepared and their structural features were thoroughly investigated. The formation of co-crystals relies on the flexibility of Ar-S-TTF and the size matches between Ar-S
  • factors to stabilize the resulting supramolecular structures. Meanwhile, the solid state absorption study indicates that the inclusion complexes display a photoexcited electronic transition between Ar–S–TTF and C60/C70. To gain further insight into the structural features of Ar-S-TTF upon complexation
  • to the short axis of C70 (10 Å), thus C70 molecules form one-dimensional (1D) columnar arrays along this direction. The structural features for both donor–acceptor interaction mode and fullerene arrangement of 7·C60, 8·C60, and 1·C70 are very similar to that of 5·C70. Type II co-crystals Among the
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Published 19 Jun 2015

Synthesis of 1,2-cis-2-C-branched aryl-C-glucosides via desulfurization of carbohydrate based hemithioacetals

  • Henok H. Kinfe,
  • Fanuel M. Mebrahtu,
  • Mandlenkosi M. Manana,
  • Kagiso Madumo and
  • Mokela S. Sokamisa

Beilstein J. Org. Chem. 2015, 11, 583–588, doi:10.3762/bjoc.11.64

Graphical Abstract
  • glycochemistry and medicinal chemistry [1][2][3][4][5]. C-Glycosides, especially aryl-C-glycosides, are the main structural features of a number of biologically active natural products such as pluramycins (antibacterial and antitumor activities), angucyclines (antibacterial, antitumor activities, and inhibitors
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Published 29 Apr 2015

Highly selective generation of vanillin by anodic degradation of lignin: a combined approach of electrochemistry and product isolation by adsorption

  • Dominik Schmitt,
  • Carolin Regenbrecht,
  • Marius Hartmer,
  • Florian Stecker and
  • Siegfried R. Waldvogel

Beilstein J. Org. Chem. 2015, 11, 473–480, doi:10.3762/bjoc.11.53

Graphical Abstract
  • be an alternative for petroleum-based production of fuels as well as fine chemicals [5][6][7]. Since the middle of the last century, the large amount of aromatic structural features making up the polymer led to much effort concerning efficient degradation methods into high value fine chemicals like
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Published 13 Apr 2015

Synthesis and chemosensing properties of cinnoline-containing poly(arylene ethynylene)s

  • Natalia A. Danilkina,
  • Petr S. Vlasov,
  • Semen M. Vodianik,
  • Andrey A. Kruchinin,
  • Yuri G. Vlasov and
  • Irina A. Balova

Beilstein J. Org. Chem. 2015, 11, 373–384, doi:10.3762/bjoc.11.43

Graphical Abstract
  • these complexes have been isolated [67]. Therefore, two structural features in the obtained oligomer chains can be responsible for the interaction with Pd 2+ cations: conjugated triple bonds (and/or the additional ethynyl moiety in the case of compound 10b) and a cinnoline ring. In order to determine
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Published 20 Mar 2015

Stereoselective cathodic synthesis of 8-substituted (1R,3R,4S)-menthylamines

  • Carolin Edinger,
  • Jörn Kulisch and
  • Siegfried R. Waldvogel

Beilstein J. Org. Chem. 2015, 11, 294–301, doi:10.3762/bjoc.11.34

Graphical Abstract
  • , if the size of the substituent is further increased, the electrochemical conversion is significantly impaired. Structural features of 8-substituted menthylamines 1. Synthetic strategies to menthylamines. Stereoselective synthesis of 8-substituted (1R,3R,4S)-menthylamines. Influence of the cathode
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Published 27 Feb 2015

Come-back of phenanthridine and phenanthridinium derivatives in the 21st century

  • Lidija-Marija Tumir,
  • Marijana Radić Stojković and
  • Ivo Piantanida

Beilstein J. Org. Chem. 2014, 10, 2930–2954, doi:10.3762/bjoc.10.312

Graphical Abstract
  • . 5.5–6) yielding reversible positive charge. Here are also described novel approaches to reversible positively charged (DPP and DIP derivatives [45]), which are related to remarkable structural features of the naturally occurring benzophenanthridine alkaloids – pH-dependent structural transition
  • between the iminium (positively charged) and alkanolamine (neutral) form [46]. Structural features of phenanthridines and phenanthridinium cations related to DNA and RNA binding Structural studies on the phenanthridine system were mostly driven by its most widespread use as DNA and RNA intercalator
  • (Figure 1) and/or fluorescent marker (ethidium bromide/propidium iodide) for ds-DNA and ds-RNA [47]. The phenanthridine structural features incorporate a unique set of properties related to the interaction with DNA and RNA (Figure 1): size and curvature of the aromatic surface corresponds to the basepair
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Published 10 Dec 2014

Anomalous diffusion of Ibuprofen in cyclodextrin nanosponge hydrogels: an HRMAS NMR study

  • Monica Ferro,
  • Franca Castiglione,
  • Carlo Punta,
  • Lucio Melone,
  • Walter Panzeri,
  • Barbara Rossi,
  • Francesco Trotta and
  • Andrea Mele

Beilstein J. Org. Chem. 2014, 10, 2715–2723, doi:10.3762/bjoc.10.286

Graphical Abstract
  • – amorphous [13], thus preventing the possibility of structural assessment via diffraction methods and making a thorough structural characterization a still open investigation field. The main structural features have been obtained, so far, by a combined use of solid state 13C CP-MAS NMR, FTIR and Raman
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Published 19 Nov 2014

Regio- and stereoselective synthesis of new diaminocyclopentanols

  • Evgeni A. Larin,
  • Valeri S. Kochubei and
  • Yuri M. Atroshchenko

Beilstein J. Org. Chem. 2014, 10, 2513–2520, doi:10.3762/bjoc.10.262

Graphical Abstract
  • -purin-6-amine (7d) were used as nucleophiles (Figure 1). Starting amines were selected based on the fact that these motifs are common structural features in drug molecules. Optimization of the epoxide ring opening reaction of 3a The opening of epoxides with nucleophiles in the presence of Lewis acid or
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Published 28 Oct 2014

Autonomous assembly of synthetic oligonucleotides built from an expanded DNA alphabet. Total synthesis of a gene encoding kanamycin resistance

  • Kristen K. Merritt,
  • Kevin M. Bradley,
  • Daniel Hutter,
  • Mariko F. Matsuura,
  • Diane J. Rowold and
  • Steven A. Benner

Beilstein J. Org. Chem. 2014, 10, 2348–2360, doi:10.3762/bjoc.10.245

Graphical Abstract
  • –Crick interactions (e.g., wobble, major groove binding) can also compete with Watson–Crickery (Figure 1). The work reported here began with the observation that several of the structural features of DNA that intrinsically limit autonomous assembly of standard DNA fragments might be overcome by adding
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Published 09 Oct 2014
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