Modern radical chemistry

Prof. Huan-Ming Huang, ShanghaiTech University

Radical chemistry has been established as a staple of organic chemistry, with new branches currently emerging and flourishing. Particularly, this is thanks to the rapid development of photoredox chemistry and electrosynthesis. In recent years, radical chemistry has also become a popular modern synthetic tool that is widely used in medicinal chemistry and material science. This thematic issue will be a collection of state-of-the-art research in this continuously growing area. The aim is to highlight the most important areas of modern radical chemistry and to direct the reader towards new concepts and future developments.

Potential topics for submitted manuscripts include, but are not limited to:

  • Photoredox chemistry
  • Electrosynthesis
  • Cooperative catalysis
  • Transition metal-catalyzed radical reactions
  • Enantioselective radical transformations
  • Radical polymerization
  • Radical chemistry in pharmaceutical science
  • Radical chemistry in material science

Still open for submission.

Back to all Issues

Photoredox catalysis enabling decarboxylative radical cyclization of γ,γ-dimethylallyltryptophan (DMAT) derivatives: formal synthesis of 6,7-secoagroclavine

  • Alessio Regni,
  • Francesca Bartoccini and
  • Giovanni Piersanti

Beilstein J. Org. Chem. 2023, 19, 918–927, doi:10.3762/bjoc.19.70

Graphical Abstract
Supp Info
Full Research Paper
Published 26 Jun 2023

Radical ligand transfer: a general strategy for radical functionalization

  • David T. Nemoto Jr,
  • Kang-Jie Bian,
  • Shih-Chieh Kao and
  • Julian G. West

Beilstein J. Org. Chem. 2023, 19, 1225–1233, doi:10.3762/bjoc.19.90

Graphical Abstract
Published 15 Aug 2023

α-(Aminomethyl)acrylates as acceptors in radical–polar crossover 1,4-additions of dialkylzincs: insights into enolate formation and trapping

  • Angel Palillero-Cisneros,
  • Paola G. Gordillo-Guerra,
  • Fernando García-Alvarez,
  • Olivier Jackowski,
  • Franck Ferreira,
  • Fabrice Chemla,
  • Joel L. Terán and
  • Alejandro Perez-Luna

Beilstein J. Org. Chem. 2023, 19, 1443–1451, doi:10.3762/bjoc.19.103

Graphical Abstract
Supp Info
Full Research Paper
Published 21 Sep 2023

Radical chemistry in polymer science: an overview and recent advances

  • Zixiao Wang,
  • Feichen Cui,
  • Yang Sui and
  • Jiajun Yan

Beilstein J. Org. Chem. 2023, 19, 1580–1603, doi:10.3762/bjoc.19.116

Graphical Abstract
Published 18 Oct 2023

Mechanisms for radical reactions initiating from N-hydroxyphthalimide esters

  • Carlos R. Azpilcueta-Nicolas and
  • Jean-Philip Lumb

Beilstein J. Org. Chem. 2024, 20, 346–378, doi:10.3762/bjoc.20.35

Graphical Abstract
Published 21 Feb 2024
Other Beilstein-Institut Open Science Activities