Non-central chirality in organic chemistry

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Editors:
Prof. Ken Tanaka, Institute of Science Tokyo
Prof. Naohiko Yoshikai, Tohoku University
 
Chirality is a fundamental concept in organic chemistry, traditionally associated with tetrahedral carbon stereocenters. However, the exploration of non-central chirality has revealed a rich landscape of stereoisomerism that extends beyond the conventional carbon-centered chirality.

This thematic issue, titled “Non-central chirality in organic chemistry”, seeks to highlight the latest advancements and innovations concerning organic molecules exhibiting axial, planar, helical, and other forms of non-central chirality. We invite submissions that delve into the synthesis, properties, and applications of these fascinating molecules. Whether through original research papers or reviews, we aim to showcase the broad impact and potential of non-central chirality in modern organic synthesis, materials science, catalysis, and beyond.

Submission deadline: August 31, 2025
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Pd-Catalyzed asymmetric allylic amination with isatin using a P,olefin-type chiral ligand with C–N bond axial chirality

  • Natsume Akimoto,
  • Kaho Takaya,
  • Yoshio Kasashima,
  • Kohei Watanabe,
  • Yasushi Yoshida and
  • Takashi Mino

Beilstein J. Org. Chem. 2025, 21, 1018–1023, doi:10.3762/bjoc.21.83

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Published 23 May 2025
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