Non-central chirality in organic chemistry
Prof. Ken Tanaka, Institute of Science Tokyo
Prof. Naohiko Yoshikai, Tohoku University
This thematic issue, titled “Non-central chirality in organic chemistry”, seeks to highlight the latest advancements and innovations concerning organic molecules exhibiting axial, planar, helical, and other forms of non-central chirality. We invite submissions that delve into the synthesis, properties, and applications of these fascinating molecules. Whether through original research papers or reviews, we aim to showcase the broad impact and potential of non-central chirality in modern organic synthesis, materials science, catalysis, and beyond.
Submission deadline: November 30, 2025
Pd-Catalyzed asymmetric allylic amination with isatin using a P,olefin-type chiral ligand with C–N bond axial chirality
- Natsume Akimoto,
- Kaho Takaya,
- Yoshio Kasashima,
- Kohei Watanabe,
- Yasushi Yoshida and
- Takashi Mino
Beilstein J. Org. Chem. 2025, 21, 1018–1023, doi:10.3762/bjoc.21.83
Advances in nitrogen-containing helicenes: synthesis, chiroptical properties, and optoelectronic applications
- Meng Qiu,
- Jing Du,
- Nai-Te Yao,
- Xin-Yue Wang and
- Han-Yuan Gong
Beilstein J. Org. Chem. 2025, 21, 1422–1453, doi:10.3762/bjoc.21.106
Wittig reaction of cyclobisbiphenylenecarbonyl
- Taito Moribe,
- Junichiro Hirano,
- Hideaki Takano,
- Hiroshi Shinokubo and
- Norihito Fukui
Beilstein J. Org. Chem. 2025, 21, 1454–1461, doi:10.3762/bjoc.21.107
Synthesis of an aza[5]helicene-incorporated macrocyclic heteroarene via oxidation of an o-phenylene-pyrrole-thiophene icosamer
- Yusuke Matsuo,
- Aoi Nakagawa,
- Shu Seki and
- Takayuki Tanaka
Beilstein J. Org. Chem. 2025, 21, 1561–1567, doi:10.3762/bjoc.21.119
pH-Controlled isomerization kinetics of ortho-disubstituted benzamidines: E/Z isomerism and axial chirality
- Ryota Kimura,
- Satoshi Ichikawa and
- Akira Katsuyama
Beilstein J. Org. Chem. 2025, 21, 1568–1576, doi:10.3762/bjoc.21.120
Synthesis of optically active folded cyclic dimers and trimers
- Ena Kumamoto,
- Kana Ogawa,
- Kazunori Okamoto and
- Yasuhiro Morisaki
Beilstein J. Org. Chem. 2025, 21, 1603–1612, doi:10.3762/bjoc.21.124
Catalytic asymmetric reactions of isocyanides for constructing non-central chirality
- Jia-Yu Liao
Beilstein J. Org. Chem. 2025, 21, 1648–1660, doi:10.3762/bjoc.21.129
Unique halogen–π association detected in single crystals of C–N atropisomeric N-(2-halophenyl)quinolin-2-one derivatives and the thione analogue
- Mai Uchibori,
- Nanami Murate,
- Kanako Shima,
- Tatsunori Sakagami,
- Ko Kanehisa,
- Gary James Richards,
- Akiko Hori and
- Osamu Kitagawa
Beilstein J. Org. Chem. 2025, 21, 1748–1756, doi:10.3762/bjoc.21.138
Chiral phosphoric acid-catalyzed asymmetric synthesis of helically chiral, planarly chiral and inherently chiral molecules
- Wei Liu and
- Xiaoyu Yang
Beilstein J. Org. Chem. 2025, 21, 1864–1889, doi:10.3762/bjoc.21.145
Synthesis of N-doped chiral macrocycles by regioselective palladium-catalyzed arylation
- Shuhai Qiu and
- Junzhi Liu
Beilstein J. Org. Chem. 2025, 21, 1917–1923, doi:10.3762/bjoc.21.149
Measuring the stereogenic remoteness in non-central chirality: a stereocontrol connectivity index for asymmetric reactions
- Ivan Keng Wee On,
- Yu Kun Choo,
- Sambhav Baid and
- Ye Zhu
Beilstein J. Org. Chem. 2025, 21, 1995–2006, doi:10.3762/bjoc.21.155
A m-quaterphenyl probe for absolute configurational assignments of primary and secondary amines
- Yuka Takeuchi,
- Mutsumi Kobayashi,
- Yuuka Gotoh,
- Mari Ikeda,
- Yoichi Habata,
- Tomohiko Shirai and
- Shunsuke Kuwahara
Beilstein J. Org. Chem. 2025, 21, 2211–2219, doi:10.3762/bjoc.21.168
Catalytic enantioselective synthesis of selenium-containing atropisomers via C–Se bond formations
- Qi-Sen Gao,
- Zheng-Wei Wei and
- Zhi-Min Chen
Beilstein J. Org. Chem. 2025, 21, 2447–2455, doi:10.3762/bjoc.21.186
