Serum heat inactivation diminishes ApoE-mediated uptake of D-Lin-MC3-DMA lipid nanoparticles

• Demian van Straten,
• Luuk van de Schepop,
• Rowan Frunt,
• Pieter Vader and
• Raymond M. Schiffelers

Beilstein J. Nanotechnol. 2025, 16, 740–748, doi:10.3762/bjnano.16.57

• plate (plates were pre-coated with gelatin for HMEC-1) and allowed to adhere overnight. Fresh media were prepared as described above. LNPs were added to the media to a final concentration of 10 nM anti-firefly luciferase siRNA and sterile filtered using a 0.45 µm PVDF filter. Per well, a total 1 pmol

The impact of tris(pentafluorophenyl)borane hole transport layer doping on interfacial charge extraction and recombination

• Konstantinos Bidinakis and
• Stefan A. L. Weber

Beilstein J. Nanotechnol. 2025, 16, 678–689, doi:10.3762/bjnano.16.52

• distributions indicative of p-i-n junctions in all devices, with a lower CPD on the ETL side where the electrons accumulate under bias. Subtracting the first measurement from the second, we filter out all information from the data that does not pertain to potential changes due to charge separation and

Colloidal few layered graphene–tannic acid preserves the biocompatibility of periodontal ligament cells

• Teissir Ben Ammar,
• Naji Kharouf,
• Dominique Vautier,
• Housseinou Ba,
• Nivedita Sudheer,
• Philippe Lavalle and
• Vincent Ball

Beilstein J. Nanotechnol. 2025, 16, 664–677, doi:10.3762/bjnano.16.51

• containing 2 μM Calcein AM and 0.25 μM SYTOX Deep Red for 30 min. After the cells were washed with PBS to optimize signal-to-noise ratio, they were imaged using epifluorescence microscopy with FITC filter set for live cells (green fluorescence) and deep red filter set for dead cells (red fluorescence

• = 405 nm, using a bandpass emission filter from 406 to 486 nm. The total nuclear volume was determined by optimizing the slicing distance [41]. CV was calculated using a MATLAB script based on Irianto et al.’s method [42], which uses a Sobel gradient-based edge detection technique to assess nuclear edge

Aprepitant-loaded solid lipid nanoparticles: a novel approach to enhance oral bioavailability

• Mazhar Hussain,
• Muhammad Farooq,
• Muhammad Asad Saeed,
• Muhammad Ijaz,
• Sherjeel Adnan,
• Zeeshan Masood,
• Muhammad Waqas,
• Wafa Ishaq and
• Nabeela Ameer

Beilstein J. Nanotechnol. 2025, 16, 652–663, doi:10.3762/bjnano.16.50

• solutions were collected through micropipette and filtered by using membrane filter (0.45 µm). The APT concentration was determined in the supernatant using a UV–vis spectrophotometer (UV 1800 Shimadzu, Japan) measuring the absorbance at λmax of 210 nm [13]. Drug content and encapsulation efficiency Drug

• content and encapsulation efficiency of APT in each formulation were determined via the total amount of drug added to the nanoparticles and the amount of free drug in the aqueous phase. Formulations equal to 2 mg of APT were dissolved in 10 mL of ethanol, filtered through a 0.45 µm membrane filter and the

Functionalized gold nanoflowers on carbon screen-printed electrodes: an electrochemical platform for biosensing hemagglutinin protein of influenza A H1N1 virus

• Carlos Enrique Torres-Méndez,
• Sharmilee Nandi,
• Klara Martinovic,
• Patrizia Kühne,
• Yifan Liu,
• Sam Taylor,
• Maria Lysandrou,
• Maria Ines Berrojo Romeyro Mascarenhas,
• Viktoria Langwallner,
• Javier Enrique Sebastián Alonso,
• Ivana Jovanovic,
• Maike Lüftner,
• Georgia-Vasiliki Gkountana,
• David Bern,
• Abdul-Raouf Atif,
• Ehsan Manouchehri Doulabi,
• Gemma Mestres and
• Masood Kamali-Moghaddam

Beilstein J. Nanotechnol. 2025, 16, 540–550, doi:10.3762/bjnano.16.42

• hemagglutinin was used as negative control. After filtrating the solutions through a 0.45 μm membrane filter to remove any suspended particles, 50 μL were deposited on the functionalized electrode and incubated at RT for 25 min. The electrode was then rinsed with 1 mL of PBS and dried under a flow of N2 gas

Engineered PEG–PCL nanoparticles enable sensitive and selective detection of sodium dodecyl sulfate: a qualitative and quantitative analysis

• Soni Prajapati and
• Ranjana Singh

Beilstein J. Nanotechnol. 2025, 16, 385–396, doi:10.3762/bjnano.16.29

• polymerization, the resulting complexes were cooled down to room temperature, dissolved in DCM, and precipitated using an excess of cold diethyl ether. The precipitates were isolated by filtration using filter paper and dried under vacuum. The collected PEG–PCL NPs were then subjected to further characterization

Graphene oxide–chloroquine conjugate induces DNA damage in A549 lung cancer cells through autophagy modulation

• Braham Dutt Arya,
• Sandeep Mittal,
• Prachi Joshi,
• Alok Kumar Pandey,
• Jaime E. Ramirez-Vick,
• Govind Gupta and
• Surinder P. Singh

Beilstein J. Nanotechnol. 2025, 16, 316–332, doi:10.3762/bjnano.16.24

• . Further, the cell suspension was diluted by adding 400 μL of 1× PBS, and red fluorescence emitted from PI was analyzed by flow cytometry (BD FACS Canto II, BD Biosciences, San Jose, CA, USA) using a 650 ± 13 nm band-pass filter. Three independent experiments were performed for each group. The proportion

Recent advances in photothermal nanomaterials for ophthalmic applications

• Jiayuan Zhuang,
• Linhui Jia,
• Chenghao Li,
• Rui Yang,
• Jiapeng Wang,
• Wen-an Wang,
• Heng Zhou and
• Xiangxia Luo

Beilstein J. Nanotechnol. 2025, 16, 195–215, doi:10.3762/bjnano.16.16

• , over time, the excessive proliferation of conjunctival fibroblasts and remodeling of collagen around the vesicles can lead to the failure of the surgical effects [144]. The primary strategy to counter fibrosis has been the use of antimetabolic drugs, but this often leads to complications like filter

• thermally destroys conjunctival fibroblasts and invasive bacteria around conjunctival vesicles, while the 5-fluorouracil (5-Fu) inhibits fibrous responses in filter vesicles, thus achieving effective IOP reduction [145]. 3.5 Endophthalmitis Endophthalmitis, commonly resulting from pathogenic infections, is

Nanocarriers and macrophage interaction: from a potential hurdle to an alternative therapeutic strategy

• Naths Grazia Sukubo,
• Paolo Bigini and
• Annalisa Morelli

Beilstein J. Nanotechnol. 2025, 16, 97–118, doi:10.3762/bjnano.16.10

Attempts to preserve and visualize protein corona on the surface of biological nanoparticles in blood serum using photomodification

• Julia E. Poletaeva,
• Anastasiya V. Tupitsyna,
• Alina E. Grigor’eva,
• Ilya S. Dovydenko and
• Elena I. Ryabchikova

Beilstein J. Nanotechnol. 2024, 15, 1654–1666, doi:10.3762/bjnano.15.130

• copper grids covered with formvar film. A drop of a sample was adsorbed for 1 min on a grid, excess of the liquid was removed by a pipette; then, the wet grid was placed on a drop of 0.5% aqueous uranyl acetate solution for 10 s, excess liquid was removed with filter paper. Grids were air-dried and

Facile synthesis of size-tunable L-carnosine-capped silver nanoparticles and their role in metal ion sensing and catalytic degradation of p-nitrophenol

• Akash Kumar,
• Ridhima Chadha,
• Abhishek Das,
• Nandita Maiti and
• Rayavarapu Raja Gopal

Beilstein J. Nanotechnol. 2024, 15, 1576–1592, doi:10.3762/bjnano.15.124

• edge filter using 532 nm as an excitation source. The Raman signal of the silicon wafer at 520 cm−1 was considered the reference point for spectrometer calibration, ensuring a spectral measurement accuracy better than 1 cm−1. The Raman spectra acquisition times were approximately 25 s for solid ʟ

Ultrablack color in velvet ant cuticle

• Vinicius Marques Lopez,
• Wencke Krings,
• Juliana Reis Machado,
• Stanislav Gorb and
• Rhainer Guillermo-Ferreira

Beilstein J. Nanotechnol. 2024, 15, 1554–1565, doi:10.3762/bjnano.15.122

• role in thermal regulation [32]. Additionally, previous studies have suggested a potential association between dark colors in velvet ants and photoprotection [16]. In this case, the dark cuticle would function as a radiation filter to prevent ultraviolet radiation from reaching the cells underneath

The round-robin approach applied to nanoinformatics: consensus prediction of nanomaterials zeta potential

• Dimitra-Danai Varsou,
• Arkaprava Banerjee,
• Joyita Roy,
• Kunal Roy,
• Giannis Savvas,
• Haralambos Sarimveis,
• Ewelina Wyrzykowska,
• Mateusz Balicki,
• Tomasz Puzyn,
• Georgia Melagraki,
• Iseult Lynch and
• Antreas Afantitis

Beilstein J. Nanotechnol. 2024, 15, 1536–1553, doi:10.3762/bjnano.15.121

• NMs’ properties when small datasets are available [4][5][6]. These in silico methodologies can be used in the early steps of the “safe-and-sustainable by design” framework and in the development of novel NMs to filter out unpromising candidates and prioritize NMs with desired properties. The rational

Lithium niobate on insulator: an emerging nanophotonic crystal for optimized light control

• Midhun Murali,
• Amit Banerjee and
• Tanmoy Basu

Beilstein J. Nanotechnol. 2024, 15, 1415–1426, doi:10.3762/bjnano.15.114

• to be used as a filter. At low contrast, the reflectance saturation is observed at a great number of bilayers and conversely, at high contrast, the reflectance saturation is observed at a low number of bilayers. It has been noted in low-loss infinite layered PhC that the significant reflection

• , but careful design, advanced fabrication, and interface engineering are crucial for success. Conclusion One-dimensional photonic crystals with lithium niobate (LN) were demonstrated using COMSOL simulation. The LN-SiO2 structure is suitable as a bandpass filter in the microwave regime. The reflectance

A biomimetic approach towards a universal slippery liquid infused surface coating

• Ryan A. Faase,
• Madeleine H. Hummel,
• AnneMarie V. Hasbrook,
• Andrew P. Carpenter and
• Joe E. Baio

Beilstein J. Nanotechnol. 2024, 15, 1376–1389, doi:10.3762/bjnano.15.111

• processing and analysis of the collected scans included a lowpass filter and took place in the “NanoScope analysis” software. Sum frequency generation vibrational spectroscopy The SFG setup used an EKSLPA Nd:YAG laser operated at 50 Hz to generate a fixed visible (532 nm−1) and tunable infrared beam (1000

Green synthesis of carbon dot structures from Rheum Ribes and Schottky diode fabrication

• Muhammed Taha Durmus and
• Ebru Bozkurt

Beilstein J. Nanotechnol. 2024, 15, 1369–1375, doi:10.3762/bjnano.15.110

• autoclave and hydrothermal synthesis was carried out at 125 °C for 12 h. After the reaction was completed, the aqueous suspension was brought to room temperature and filtered with ordinary filter paper. The filtrate was passed through a 0.22 µm membrane filter and centrifuged at 10000 rpm for 30 min. The

A low-kiloelectronvolt focused ion beam strategy for processing low-thermal-conductance materials with nanoampere currents

• Annalena Wolff,
• Nico Klingner,
• William Thompson,
• Yinghong Zhou,
• Jinying Lin and
• Yin Xiao

Beilstein J. Nanotechnol. 2024, 15, 1197–1207, doi:10.3762/bjnano.15.97

• current, 1 µs dwell time, 128 frames integration filter and 1024 × 882 pixel resolution with an Everhart–Thornley detector. FIB TEM-lamella preparation and TEM analysis To verify if the collagen was heat-damaged when processing the sample using nanoampere range currents and different incident ion energies

Effect of wavelength and liquid on formation of Ag, Au, Ag/Au nanoparticles via picosecond laser ablation and SERS-based detection of DMMP

• Sree Satya Bharati Moram,
• Chandu Byram and
• Venugopal Rao Soma

Beilstein J. Nanotechnol. 2024, 15, 1054–1069, doi:10.3762/bjnano.15.86

• -dispersive X-ray spectroscopy. Furthermore, NPs of various sizes ranging from 6 to 35 nm were loaded onto a filter paper by a simple and effective drop-casting approach to achieve flexible surface-enhanced Raman spectroscopy (SERS) substrates/sensors. These substrates were tested using a simple, portable

• substrates is the central aspect of the sensing field because of its simple sample collection from any rough surface [36][40]. Filter paper (FP) SERS substrates are rigorously investigated for the detection of hazardous dye molecules such as crystal violet (CV) and malachite green (MG) on fish [41

• ], pesticides on vegetables, dals [42], fruit surfaces [43], and explosives on rough surfaces [44][45]. In the last few years, our group has been continuously working on developing a flexible SERS substrate for the detection of various types of hazardous molecules: aggregated Ag and Au NPs on filter paper [46

Therapeutic effect of F127-folate@PLGA/CHL/IR780 nanoparticles on folate receptor-expressing cancer cells

• Thi Ngoc Han Pham,
• Phuong-Thao Dang-Luong,
• Hong-Phuc Nguyen,
• Loc Le-Tuan,
• Xuan Thang Cao,
• Thanh-Danh Nguyen,
• Vy Tran Anh and
• Hieu Vu_Quang

Beilstein J. Nanotechnol. 2024, 15, 954–964, doi:10.3762/bjnano.15.78

• , respectively (Table 1), which is acceptable for systemic administration. According to a review, these negative charges could reduce kidney excretion. The endothelial glycocalyx layer, glomerular basement membrane, and podocyte glycocalyx layer have negative charges, which filter positive nanoparticles faster

Synthesis of silver–palladium Janus nanoparticles using co-sputtering of independent sources: experimental and theorical study

• Maria J. Martínez-Carreón,
• Francisco Solís-Pomar,
• Abel Fundora,
• Claudio D. Gutiérrez-Lazos,
• Sergio Mejía-Rosales,
• Hector N. Fernández-Escamilla,
• Jonathan Guerrero-Sánchez,
• Manuel F. Meléndrez and
• Eduardo Pérez-Tijerina

Beilstein J. Nanotechnol. 2024, 15, 808–816, doi:10.3762/bjnano.15.67

• % purity; the sputtered atoms traveled to the second chamber, where a shower of Pd atoms was generated on the second magnetron from a palladium target with 99.99% purity. The BNPs generated by condensation passed through a quadrupole mass filter for size selection and were finally deposited on holey carbon

• connected by a Ag3Pd interface (Ag/AgPd/Pd model). Size distribution profiles determined using a quadrupole mass filter. HRTEM micrographs of AgPd nanoparticles. (a) Janus-type structure. (b) Janus-type structure. Calculation of interplanar distances in silver–palladium nanoparticles. (a) HRTEM micrograph

Electron-induced ligand loss from iron tetracarbonyl methyl acrylate

• Hlib Lyshchuk,
• Atul Chaudhary,
• Thomas F. M. Luxford,
• Miloš Ranković,
• Jaroslav Kočišek,
• Juraj Fedor,
• Lisa McElwee-White and
• Pamir Nag

Beilstein J. Nanotechnol. 2024, 15, 797–807, doi:10.3762/bjnano.15.66

• , kept at around 25 °C, in a glass container through the gas inlet system. Electrostatic ion optics lenses extract and guide all produced anions from the interaction region towards a quadrupole mass filter that only lets pass anions with a given mass-to-charge ratio (m/z). Selected anions are then

• et al. [10] was recorded with a quadrupole mass filter) one has to keep in mind possible mass-dependent transmissions; however, for iron pentacarbonyl, the strong dominance of Fe+ and FeCO+ is also visible in all of the older mass spectra (e.g., in the data recommended by NIST [35]). In this sense

Electrospun polysuccinimide scaffolds containing different salts as potential wound dressing material

• Veronika Pálos,
• Krisztina S. Nagy,
• Rita Pázmány,
• Krisztina Juriga-Tóth,
• Bálint Budavári,
• Judit Domokos,
• Dóra Szabó,
• Ákos Zsembery and
• Angela Jedlovszky-Hajdu

Beilstein J. Nanotechnol. 2024, 15, 781–796, doi:10.3762/bjnano.15.65

• pellet was filtered and washed using a vacuum filter to remove the phosphoric acid catalyst and the unreacted ʟ-aspartic acid monomeric molecules. Then, the pellet was mixed in distilled water for 10 min. This step was repeated until the pH of the filtrate changed from acidic to neutral. Finally, the PSI

Functional fibrillar interfaces: Biological hair as inspiration across scales

• Guillermo J. Amador,
• Brett Klaassen van Oorschot,
• Caiying Liao,
• Jianing Wu and
• Da Wei

Beilstein J. Nanotechnol. 2024, 15, 664–677, doi:10.3762/bjnano.15.55

• classifications. Future research linking form and function in microbial hairs may lead to a better understanding of their evolution, as well as providing inspiration for the development of functional fibrillar structures at the micrometer and nanometer scales. Filter feeding Locomotion is key for searching for

• food, and hairs may also serve crucial roles in feeding, particularly via filtering. Filter feeding uses a porous material to capture prey and nutrients in fluid flows. Dense arrays of hairs may serve as the porous material that captures the food, separating it from the surrounding flow or from other

• fibers, or baleen, in their mouths instead of teeth to filter and capture prey [117][118][119]. When feeding, the whales use three different strategies, depending on their species. Bowhead and right whales (Balaenidae) use ram filter feeding where they continuously swim through groups of prey with their

Stiffness calibration of qPlus sensors at low temperature through thermal noise measurements

• Laurent Nony,
• Sylvain Clair,
• Daniel Uehli,
• Aitziber Herrero,
• Jean-Marc Themlin,
• Andrea Campos,
• Franck Para,
• Alessandro Pioda and
• Christian Loppacher

Beilstein J. Nanotechnol. 2024, 15, 580–602, doi:10.3762/bjnano.15.50

• a thermostat. The PSD of the stochastic thermal force giving rise to the fluctuations of the SHO is derived as well, which is used in the numerical simulations. Supporting Information File 4 discusses the relevance of a digital antialiasing filter on the measured thermal noise PSD. Stiffness

• this signal. An analog low-pass filter in the OC4 acts as an antialiasing filter before digital conversion by an ADC. It is implemented as a third-order overall Butterworth filter with a Sallen–Key topology and with a fixed cut-off frequency of 5 MHz, meaning that dampening is 60 dB per decade. There

• is no additional filter in the analog part, and there is no antialiasing filter in the digital domain. Before thermal noise measurements, the qPlus deflections are accurately calibrated into metric units with a custom-made script implemented in the Nanonis MIMEA control unit that performs the

Directed growth of quinacridone chains on the vicinal Ag(35 1 1) surface

• Niklas Humberg,
• Lukas Grönwoldt and
• Moritz Sokolowski

Beilstein J. Nanotechnol. 2024, 15, 556–568, doi:10.3762/bjnano.15.48

• SPIP [29], which included filtering out noise and an adjustment of the contrast. Additionally, to some images, a Prewitt or Roberts filter for edge enhancement was applied in order to enhance the visibility of the step edges. The structure models were drawn with the free software Graphics Layout Engine

• = 25 pA) of QA on the Ag(35 1 1) surface deposited at a sample temperature of 400 K. It shows an area with several step edges running vertically through the image, which are highlighted by the dashed black lines. (b) The same STM image as in panel (a) with a Prewitt filter for better visibility of the