Emerging strategies in the sustainable removal of antibiotics using semiconductor-based photocatalysts

• Yunus Ahmed,
• Keya Rani Dutta,
• Parul Akhtar,
• Md. Arif Hossen,
• Md. Jahangir Alam,
• Obaid A. Alharbi,
• Hamad AlMohamadi and
• Abdul Wahab Mohammad

Beilstein J. Nanotechnol. 2025, 16, 264–285, doi:10.3762/bjnano.16.21

• , including biochar, metal-organic frameworks (MOFs), functionalized mesoporous silica, porous organic polymers, zeolite, and derivatives of graphene. These substances act as a support for metal oxides and immobilize the catalyst, increase the catalyst surface area, and improve the chemical stability

Radiosensitizing properties of dual-functionalized carbon nanostructures loaded with temozolomide

• Radmila Milenkovska,
• Nikola Geskovski,
• Dushko Shalabalija,
• Ljubica Mihailova,
• Petre Makreski,
• Dushko Lukarski,
• Igor Stojkovski,
• Maja Simonoska Crcarevska and
• Kristina Mladenovska

Beilstein J. Nanotechnol. 2025, 16, 229–251, doi:10.3762/bjnano.16.18

• chemical modifications and/or coupling with hydrophilic polymers. TMZ was successfully incorporated in magnetic NPs [36], mesoporous silica NPs [37], and NPs made of silver [38], zinc oxide [39], and gold [40], all of them showing high accumulation in tumor cells and cytotoxic activity in vitro and in vivo

A review of metal-organic frameworks and polymers in mixed matrix membranes for CO₂ capture

• Charlotte Skjold Qvist Christensen,
• Nicholas Hansen,
• Mahboubeh Motadayen,
• Nina Lock,
• Martin Lahn Henriksen and
• Jonathan Quinson

Beilstein J. Nanotechnol. 2025, 16, 155–186, doi:10.3762/bjnano.16.14

• synthesis [32]. The resulting constructions have pore sizes ranging from microporous (<2 nm) to mesoporous (2–50 nm) [30][36]. This simple strategy has led to substantial exploration of various MOFs with different structures and properties for various applications in heterogeneous catalysis, biomedicine

TiO₂ immobilized on 2D mordenite: effect of hydrolysis conditions on structural, textural, and optical characteristics of the nanocomposites

• Marina G. Shelyapina,
• Rosario Isidro Yocupicio-Gaxiola,
• Gleb A. Valkovsky and
• Vitalii Petranovskii

Beilstein J. Nanotechnol. 2025, 16, 128–140, doi:10.3762/bjnano.16.12

• distance and, hence, the mesopore size, but also the aluminum distribution and acidic properties of the obtained material, which are key parameters for catalysts [5][7][8][9][10]. One widely used component for the synthesis of 2D zeolites is CTAB [5][9][11][12][13]. To prepare mesoporous materials from

• immobilization of TiO2 nanoparticles is of great importance. Many materials are considered as a possible support for immobilization, including porous ceramics [15], glass [16][17], porous carbon materials [18][19], mesoporous silica [20][21][22][23], and zeolites [24][25][26][27]. Recent studies have confirmed

• that direct synthesis of TiO2 in mesoporous silica or zeolites provides strong immobilization of TiO2 nanoparticles through Ti–O–Si bonding [21][22][23]. Previously, we reported the results of the trial synthesis of a new TiO2/2D mordenite nanocomposite [28]. The material was obtained from a composite

Nanocarriers and macrophage interaction: from a potential hurdle to an alternative therapeutic strategy

• Naths Grazia Sukubo,
• Paolo Bigini and
• Annalisa Morelli

Beilstein J. Nanotechnol. 2025, 16, 97–118, doi:10.3762/bjnano.16.10

• into clinical practice requires overcoming key challenges, such as ensuring molecular stability, achieving targeted delivery, and minimizing immune activation. Ongoing research is addressing these barriers by advancing RNA delivery systems [77]. For example, mesoporous silica NPs have been utilized to

Instance maps as an organising concept for complex experimental workflows as demonstrated for (nano)material safety research

• Benjamin Punz,
• Maja Brajnik,
• Joh Dokler,
• Jaleesia D. Amos,
• Litty Johnson,
• Katie Reilly,
• Anastasios G. Papadiamantis,
• Amaia Green Etxabe,
• Lee Walker,
• Diego S. T. Martinez,
• Steffi Friedrichs,
• Klaus M. Weltring,
• Nazende Günday-Türeli,
• Claus Svendsen,
• Christine Ogilvie Hendren,
• Mark R. Wiesner,
• Martin Himly,
• Iseult Lynch and
• Thomas E. Exner

Beilstein J. Nanotechnol. 2025, 16, 57–77, doi:10.3762/bjnano.16.7

Theoretical study of the electronic and optical properties of a composite formed by the zeolite NaA and a magnetite cluster

• Joel Antúnez-García,
• Roberto Núñez-González,
• Vitalii Petranovskii,
• H’Linh Hmok,
• Armando Reyes-Serrato,
• Fabian N. Murrieta-Rico,
• Mufei Xiao and
• Jonathan Zamora

Beilstein J. Nanotechnol. 2025, 16, 44–53, doi:10.3762/bjnano.16.5

• fewer studies on the cytotoxicity of nanoparticles on zeolite carriers than other mesoporous matrices, most articles report low cytotoxicity of zeolites. Zeolites are classified as “Safe Substances for Food and Feed Additives” by the European Food Safety Authorities [49] and are “Generally Recognized as

Dual-functionalized architecture enables stable and tumor cell-specific SiO₂NPs in complex biological fluids

• Iris Renata Sousa Ribeiro,
• Raquel Frenedoso da Silva,
• Romênia Ramos Domingues,
• Adriana Franco Paes Leme and
• Mateus Borba Cardoso

Beilstein J. Nanotechnol. 2024, 15, 1238–1252, doi:10.3762/bjnano.15.100

• active groups (amino, mercapto, or carboxylic functionalities) to interact with cells, viruses, and bacteria [17][18][20]. Pan et al. [24] developed mesoporous silica nanoparticles (SiO2NPs) covalently attached to (i) poly(oligo(ethylene glycol) monomethyl ether methacrylate) for improved stabilization

• proves to be a successful model that can be extended to other types of NPs, such as degradable mesoporous silica nanoparticles, which are highly porous and can degrade under specific biological conditions, thus preventing inconvenient accumulation in the body. a) Representation of the synthesis steps of

Recent updates in applications of nanomedicine for the treatment of hepatic fibrosis

• Damai Ria Setyawati,
• Fransiska Christydira Sekaringtyas,
• Riyona Desvy Pratiwi,
• A’liyatur Rosyidah,
• Rohimmahtunnissa Azhar,
• Nunik Gustini,
• Gita Syahputra,
• Idah Rosidah,
• Etik Mardliyati,
• Tarwadi and
• Sjaikhurrizal El Muttaqien

Beilstein J. Nanotechnol. 2024, 15, 1105–1116, doi:10.3762/bjnano.15.89

• hepatobiliary clearance in vivo. For example, positively charged mesoporous silica NPs (MSNPs) underwent significant uptake by hepatocytes, while MSNPs with negative charges were rapidly internalized by Kupffer cells in liver sinusoids [33]. The negative charge of the nanocarriers could facilitate efficient

Classification and application of metal-based nanoantioxidants in medicine and healthcare

• Nguyen Nhat Nam,
• Nguyen Khoi Song Tran,
• Tan Tai Nguyen,
• Nguyen Ngoc Trai,
• Nguyen Phuong Thuy,
• Hoang Dang Khoa Do,
• Nhu Hoa Thi Tran and
• Kieu The Loan Trinh

Beilstein J. Nanotechnol. 2024, 15, 396–415, doi:10.3762/bjnano.15.36

• collaborators synthesized mesoporous carbon nanospheres (PMCSs) derived from a MOF precursor, exhibiting dual photodynamic and photothermal characteristics. Utilizing this framework, concentration and temperature at thrombotic sites were elevated significantly upon local irradiation (808 nm laser), resulting in

Berberine-loaded polylactic acid nanofiber scaffold as a drug delivery system: The relationship between chemical characteristics, drug-release behavior, and antibacterial efficiency

• Le Thi Le,
• Hue Thi Nguyen,
• Liem Thanh Nguyen,
• Huy Quang Tran and
• Thuy Thi Thu Nguyen

Beilstein J. Nanotechnol. 2024, 15, 71–82, doi:10.3762/bjnano.15.7

• , iron oxide, and mesoporous silica nanoparticles) [4]. Additionally, nanocarrier-free systems, such as drug nanocrystals, are also used to improve the delivery of poorly soluble drugs [5][6]. In our previous study, the saturation concentration of BBR in water was 2.0 mg/mL, while BBR nanoparticles

Elasticity, an often-overseen parameter in the development of nanoscale drug delivery systems

• Agnes-Valencia Weiss and
• Marc Schneider

Beilstein J. Nanotechnol. 2023, 14, 1149–1156, doi:10.3762/bjnano.14.95

• variable elasticity were prepared by immersing mesoporous silica nanoparticles in carboxybetaine methacrylate (CBMA) and crosslinking those with different amounts of carboxybetaine dimethacrylate (CBMAX). Particles with Young’s moduli between 4.5 and 162 MPa (measured in air) were obtained. By measuring

• -mediated uptake mechanisms, whereas hard NLGs are predominantly internalized via the clathrin-mediated pathway [32]. Another example of the enhanced tumor accumulation of softer nanoparticles is presented by Tao et al. Even though the hyaluronic-acid-modified mesoporous organosilica nanoparticles (MMONs

Nanoarchitectonics of photothermal materials to enhance the sensitivity of lateral flow assays

• Elangovan Sarathkumar,
• Rajasekharan S. Anjana and
• Ramapurath S. Jayasree

Beilstein J. Nanotechnol. 2023, 14, 988–1003, doi:10.3762/bjnano.14.82

• ]. NIR light irradiation for 10 min can yield temperatures up to 61 °C in mesoporous PDA with a photoconversion efficiency of 26.7%. Despite the advantages, many of the polymer nanoparticles show strong photoluminescence and do not withstand long-term light irradiation. To overcome this challenge, hybrid

Carboxylic acids and light interact to affect nanoceria stability and dissolution in acidic aqueous environments

• Matthew L. Hancock,
• Eric A. Grulke and
• Robert A. Yokel

Beilstein J. Nanotechnol. 2023, 14, 762–780, doi:10.3762/bjnano.14.63

• resulted in loss or overcoating of the surface citrate, and, in some cases, agglomeration [10]. Exposure to vitamin C and glutathione led to dissolution-accompanied aggregation of mesoporous silica CeO2 nanoparticles [35]. The shortening of ceria nanorods from 25 to 8 nm after 14 days at 200 °C was

Metal-organic framework-based nanomaterials as opto-electrochemical sensors for the detection of antibiotics and hormones: A review

• Akeem Adeyemi Oladipo,
• Saba Derakhshan Oskouei and
• Mustafa Gazi

Beilstein J. Nanotechnol. 2023, 14, 631–673, doi:10.3762/bjnano.14.52

• oxides) [63][64][65][66][67][68][69]. This is motivated by their large surface area, which can facilitate the loading of nanoparticles. Additionally, MOFs have been converted into their electrochemically active derivatives, such as mesoporous carbon composites and porous metal oxides, to achieve an

Plasmonic nanotechnology for photothermal applications – an evaluation

• A. R. Indhu,
• L. Keerthana and
• Gnanaprakash Dharmalingam

Beilstein J. Nanotechnol. 2023, 14, 380–419, doi:10.3762/bjnano.14.33

Recent progress in cancer cell membrane-based nanoparticles for biomedical applications

• Qixiong Lin,
• Yueyou Peng,
• Yanyan Wen,
• Xiaoqiong Li,
• Donglian Du,
• Weibin Dai,
• Wei Tian and
• Yanfeng Meng

Beilstein J. Nanotechnol. 2023, 14, 262–279, doi:10.3762/bjnano.14.24

• (NIR) radiation to ablate cells or trigger the release of related therapeutic drugs [94][96]. PTT is characterized by noninvasiveness, deep tissue penetration, and high anticancer efficiency, showing good prospects in clinical treatment [97]. Biomimetic NPs of mesoporous polydopamine nanocarriers have

• the ability to target tumor tissue and enable multimodal imaging was fabricated for more efficient diagnosis and treatment by the Shu group. The biomimetic nanoformulation utilized hollow mesoporous Prussian blue nanoparticles as the core, endowing it with photothermal conversion and photoacoustic

Nanotechnology – a robust tool for fighting the challenges of drug resistance in non-small cell lung cancer

• Filip Gorachinov,
• Fatima Mraiche,
• Diala Alhaj Moustafa,
• Ola Hishari,
• Yomna Ismail,
• Jensa Joseph,
• Maja Simonoska Crcarevska,
• Marija Glavas Dodov,
• Nikola Geskovski and
• Katerina Goracinova

Beilstein J. Nanotechnol. 2023, 14, 240–261, doi:10.3762/bjnano.14.23

• barriers by the use of different groups of particles carrying various functional modalities. Tasciotti et al. proposed a multistage delivery system composed of stage-1 mesoporous silica particles with improved deposition in the vascular endothelium, optimized for crossing the endothelial barrier through

• surface, triggered by protease degradation after tumor homing by the EPR effect [112]. Mesoporous silica vesicles (MSVs; dav = 3 μm) with high affinity to tumor vasculature were also described by Blanco et al. as a platform for the triggered release of various therapeutic nanoscale vectors (liposomes

Cyclodextrins as eminent constituents in nanoarchitectonics for drug delivery systems

• Makoto Komiyama

Beilstein J. Nanotechnol. 2023, 14, 218–232, doi:10.3762/bjnano.14.21

• are disassembled to release the encapsulated drugs. β-CyD units have been connected to mesoporous silica nanoparticles via a disulfide linkage, and azobenzene molecules have been bound to a galactose-grafted polymer [49]. Prior to photoirradiation, the trans isomer of azobenzene forms an inclusion

• , only the trans isomer of mAzo efficiently forms inclusion complexes with β-CyD (Figure 2). The surface of mesoporous silica nanoparticles was modified with β-CyD and covered with a polymer bearing mAzo units [51]. Drugs were loaded in the pores of the silica nanoparticles. Prior to photoirradiation

• arylazopyrazole to the cis form. Accordingly, the inclusion complexes were spontaneously broken down. NaYF4:Yb,Tm@NaLuF4 upconversion nanoparticles were used for DDSs [56]. The surface of these nanoparticles was covered with a mesoporous silica layer, and drugs were encapsulated in the mesopores. To the

Studies of probe tip materials by atomic force microscopy: a review

• Ke Xu and
• Yuzhe Liu

Beilstein J. Nanotechnol. 2022, 13, 1256–1267, doi:10.3762/bjnano.13.104

• bias-assisted electroreduced gold ions in mesoporous silica films on a conductive substrate. It works in the air with high relative humidity (RH) at room temperature and leads to the growth of fine wires attached to the tip with tens to hundreds of nanometers. Under room temperature conditions with

• high RH, the gold ions loaded in the specific substrate of the mesoporous silica layer are biased, and the gold ions therein migrate upward and accumulate at the tip site of the probe, forming gold nanowires. The length of the gold nanowires can be effectively tuned in the range of 10–100 nm with a

Design of surface nanostructures for chirality sensing based on quartz crystal microbalance

• Yinglin Ma,
• Xiangyun Xiao and
• Qingmin Ji

Beilstein J. Nanotechnol. 2022, 13, 1201–1219, doi:10.3762/bjnano.13.100

• chiral anion induction and combined with CD spectroscopy to achieve chiral recognition with a relatively larger size of poly(propiolic acid) sodium salt [116]; He et al. used chiral mesoporous SiO2 and combined with gas chromatography (GC) achieved chiral separation of amino acid derivatives and other

Recent advances in green carbon dots (2015–2022): synthesis, metal ion sensing, and biological applications

• Aisha Kanwal,
• Naheed Bibi,
• Sajjad Hyder,
• Arif Muhammad,
• Hao Ren,
• Jiangtao Liu and
• Zhongli Lei

Beilstein J. Nanotechnol. 2022, 13, 1068–1107, doi:10.3762/bjnano.13.93

• no other chemical reagent. The lignin content of the leaves and shafts of date palm leaves is 25 g/100 g, which helped to obtain mesoporous CDs of high quality having high storage and photostability [68]. Leaves of Prosopis juliflora as a natural and inexpensive precursor yielded CDs that acted as a

Biomimetic chitosan with biocomposite nanomaterials for bone tissue repair and regeneration

• Se-Kwon Kim,
• Sesha Subramanian Murugan,
• Pandurang Appana Dalavi,
• Sebanti Gupta,
• Sukumaran Anil,
• Gi Hun Seong and
• Jayachandran Venkatesan

Beilstein J. Nanotechnol. 2022, 13, 1051–1067, doi:10.3762/bjnano.13.92

• weeks. The emergence of new bone in the defective region is confirmed by microscale computational micrographs and staining assay findings [98]. Ning et al. (2019) developed glycyl-ʟ-histidyl-ʟ-lysine-containing copper ions integrated with mesoporous silica nanoparticles (MSN) and chitosan. Further, the

• such as mesoporous bioactive glass possess exceptional osteogenic properties [121][122]. Diatomite and chitosan-containing scaffolding systems were developed by Tamburaci and co-workers. The developed composite shows excellent cell proliferation, mineralisation, and alkaline phosphatase activity on MG

Spindle-like MIL101(Fe) decorated with Bi₂O₃ nanoparticles for enhanced degradation of chlortetracycline under visible-light irradiation

• Chen-chen Hao,
• Fang-yan Chen,
• Kun Bian,
• Yu-bin Tang and
• Wei-long Shi

Beilstein J. Nanotechnol. 2022, 13, 1038–1050, doi:10.3762/bjnano.13.91

• efficient photocatalysts for CTC degradation. Metal–organic frameworks (MOFs) are a kind of micro- or mesoporous materials established by the self-assembly of organic linkers and metal-cluster or metal-ion nodes [19]. The MOF materials possess large surface areas, high pore volume, tunability, uniform

Electrocatalytic oxygen reduction activity of AgCoCu oxides on reduced graphene oxide in alkaline media

• Iyyappan Madakannu,
• Indrajit Patil,
• Bhalchandra Kakade and
• Kasibhatta Kumara Ramanatha Datta

Beilstein J. Nanotechnol. 2022, 13, 1020–1029, doi:10.3762/bjnano.13.89

• et al. prepared supportless Ag nanowires and 1D mesoporous hollow AgPdPt nanotubes by micelle-assisted galvanic replacement followed by acid etching. They found that hollow AgPdPt structures exhibited a better ORR activity with onset and half-wave potential of 0.99 V and 0.90 V vs RHE, respectively