Key for crossing the BBB with nanoparticles: the rational design

• Sonia M. Lombardo,
• Marc Schneider,
• Akif E. Türeli and
• Nazende Günday Türeli

Beilstein J. Nanotechnol. 2020, 11, 866–883, doi:10.3762/bjnano.11.72

• factors needs to be taken into account when developing a carrier system for this purpose. Depending on the chosen pathway to cross the BBB, nanoparticle material, size and surface properties such as functionalization and charge should be tailored to fit the specific route of BBB crossing. Keywords: gold

• dalargin [49]. Thus, it was proposed that the binding of doxorubicin led to an alteration of the nanoparticle surface properties that allowed ApoE and B to be bound. It was then concluded that the BBB permeation ability of nanoparticles was not only dependent of the surfactant coating but also of the

• suggestion from Kreuter et al. that the core of the nanoparticles could influence the surface properties of the nanoparticles and therefore their ability to bind with apolipoproteins in the blood [54]. PS80 coating was also successful for PLA-b-PEG nanoparticles [58] but failed for PLA nanoparticles [59

Identification of physicochemical properties that modulate nanoparticle aggregation in blood

• Ludovica Soddu,
• Duong N. Trinh,
• Eimear Dunne,
• Dermot Kenny,
• Giorgia Bernardini,
• Ida Kokalari,
• Arianna Marucco,
• Marco P. Monopoli and
• Ivana Fenoglio

Beilstein J. Nanotechnol. 2020, 11, 550–567, doi:10.3762/bjnano.11.44

• –protein interaction may lead to bridging among particles, thus promoting agglomeration [23]. In the present study, a set of six silica and carbon NPs of known size and morphology was used to evaluate the effect of the size and surface properties on the protein corona composition, platelet activation and

• composition between the two materials has some similarities when incubated at 10% plasma; however, it becomes highly specific to the NP surface properties at higher concentrations as confirmed by the significant difference in the corona composition. In particular, at 10% of plasma, both NPs preferentially

• aggregation. However, in this case the effect is not due to the interaction with integrin, but it is a non-specific process due to the tendency of fibrinogen to form fibrils similar to fibrin. This tendency is a consequence of the specific fibrinogen arrangement onto surfaces, modulated by the surface

Multilayer capsules made of weak polyelectrolytes: a review on the preparation, functionalization and applications in drug delivery

• Varsha Sharma and
• Anandhakumar Sundaramurthy

Beilstein J. Nanotechnol. 2020, 11, 508–532, doi:10.3762/bjnano.11.41

• of the capsules and contamination issues during the core dissolution processes. Thus, despite the lower EE and drug absorption in the capsule wall rather than in the interior, pH and salt based approaches are the most widely used in weak PE systems. Functionalization The surface properties of the

• capsule determine its permeability, which in turn influences the release profile. In order to alter the surface properties, the PE multilayer capsules can be functionalized with various organic and inorganic materials that would lead to a new way for different biological applications. These include metal

Current measurements in the intermittent-contact mode of atomic force microscopy using the Fourier method: a feasibility analysis

• Berkin Uluutku and
• Santiago D. Solares

Beilstein J. Nanotechnol. 2020, 11, 453–465, doi:10.3762/bjnano.11.37

• surface properties, such as topography, viscoelasticity, electrical potential and conductivity. Some of these properties are measured using contact methods (static contact or intermittent contact), while others are measured using noncontact methods. Some properties can be measured using different

Atomic-resolution imaging of rutile TiO₂(110)-(1 × 2) reconstructed surface by non-contact atomic force microscopy

• Daiki Katsube,
• Shoki Ojima,
• Eiichi Inami and
• Masayuki Abe

Beilstein J. Nanotechnol. 2020, 11, 443–449, doi:10.3762/bjnano.11.35

• microscopy (STM) [10][11][12], transmission electron microscopy [13][14], and density functional theory (DFT) [15][16][17][18][19]. These studies have determined many surface properties such as structure, local defects, and adsorption sites. The (1 × 1) surface transforms to the (1 × 2) surface by oxygen

Synthesis and enhanced photocatalytic performance of 0D/2D CuO/tourmaline composite photocatalysts

• Changqiang Yu,
• Min Wen,
• Zhen Tong,
• Shuhua Li,
• Yanhong Yin,
• Xianbin Liu,
• Yesheng Li,
• Tongxiang Liang,
• Ziping Wu and
• Dionysios D. Dionysiou

Beilstein J. Nanotechnol. 2020, 11, 407–416, doi:10.3762/bjnano.11.31

• ) spectra were analyzed using an A300 spectrometer (Bruker, Germany) with DMPO as a free radical scavenger under visible light irradiation (λ = 420 nm) for 20 min. The surface properties were characterized via an ASAP 2020 instrument (Micromeritics, USA). The zeta potential was measured with a ZETASIZER

Interactions at the cell membrane and pathways of internalization of nano-sized materials for nanomedicine

• Valentina Francia,
• Daphne Montizaan and
• Anna Salvati

Beilstein J. Nanotechnol. 2020, 11, 338–353, doi:10.3762/bjnano.11.25

• ability, but also particle size, stability, and overall surface properties [36]. Recent guidelines have started to highlight the importance of testing nanomedicines in the presence of relevant biological media in order to take corona effects into account [41]. Several strategies have been developed to try

Phase inversion-based nanoemulsions of medium chain triglyceride as potential drug delivery system for parenteral applications

• Eike Folker Busmann,
• Dailén García Martínez,
• Henrike Lucas and
• Karsten Mäder

Beilstein J. Nanotechnol. 2020, 11, 213–224, doi:10.3762/bjnano.11.16

• Kolliphor HS 15. The experimental results indicate, that nanoemulsions with particles of small and tunable size can be easily formed without homogenization by thermal cycling. Keywords: cellular toxicity; isotonicity; nanoemulsion; phase inversion; solvent free; surface properties; Introduction Nanoscaled

• surfactant show different effects on the final product. For example, these factors influence the feasibility of forming stable nanostructures, they affect the phase inversion zone, the in vitro cellular toxicity and the above mentioned particle and surface properties [3][4][12]. There are marketed drug

Size effects of graphene nanoplatelets on the properties of high-density polyethylene nanocomposites: morphological, thermal, electrical, and mechanical characterization

• Tuba Evgin,
• Alpaslan Turgut,
• Georges Hamaoui,
• Zdenko Spitalsky,
• Nicolas Horny,
• Matej Micusik,
• Mihai Chirtoc,
• Mehmet Sarikanat and
• Maria Omastova

Beilstein J. Nanotechnol. 2020, 11, 167–179, doi:10.3762/bjnano.11.14

• cooling. Characterization X-ray photoelectron spectroscopy (K-alpha X-ray photoelectron spectrometer (XPS) system, Thermo Fisher Scientific) analysis was used to characterize the surface properties of the GnPs. The GnP and nanocomposite morphologies were investigated by SEM (XL 30S FEG electron microscope

Molecular architectonics of DNA for functional nanoarchitectures

• Debasis Ghosh,
• Lakshmi P. Datta and
• Thimmaiah Govindaraju

Beilstein J. Nanotechnol. 2020, 11, 124–140, doi:10.3762/bjnano.11.11

• affect the spectroscopic behavior and the solution properties of the dye. DNA–metal nanoparticle architectures Interactions of DNA with nanoparticles are an attractive area for the fabrication of functional DNA nanoarchitectures [96]. The surface properties of the nanoparticles are greatly influenced by

Bombesin receptor-targeted liposomes for enhanced delivery to lung cancer cells

• Mohammad J. Akbar,
• Pâmela C. Lukasewicz Ferreira,
• Melania Giorgetti,
• Leanne Stokes and
• Christopher J. Morris

Beilstein J. Nanotechnol. 2019, 10, 2553–2562, doi:10.3762/bjnano.10.246

• polydisperse proteins of different sizes [27]. Indeed, the surface properties of various nanoparticles have been shown to change dramatically in the presence of plasma or serum [28] with the establishment of an adsorbed protein corona around the nanoparticle. It is now widely accepted that the particle protein

Formation of metal/semiconductor Cu–Si composite nanostructures

• Natalya V. Yumozhapova,
• Andrey V. Nomoev,
• Vyacheslav V. Syzrantsev and
• Erzhena C. Khartaeva

Beilstein J. Nanotechnol. 2019, 10, 2497–2504, doi:10.3762/bjnano.10.240

• create composite Janus-like or core–shell nanoparticles. The size and the unique morphology at the nanoscale provide new optical, electronic, magnetic and surface properties to these nanoparticles [1][2]. In addition, it is possible to combine materials of which alloys do not exist in nature. The shell

Self-assembly of a terbium(III) 1D coordination polymer on mica

• Quentin Evrard,
• Giuseppe Cucinotta,
• Felix Houard,
• Guillaume Calvez,
• Yan Suffren,
• Carole Daiguebonne,
• Olivier Guillou,
• Andrea Caneschi,
• Matteo Mannini and
• Kevin Bernot

Beilstein J. Nanotechnol. 2019, 10, 2440–2448, doi:10.3762/bjnano.10.234

• -surface properties [11][12]. The terbium(III) ion, (TbIII), is a particularly suitable candidate for the creation of surface-based magnetic and luminescent devices [5][6]. It has one of the highest magnetic moments of all elements in the periodic table, and it shows a very strong magnetic anisotropy when

Ion mobility and material transport on KBr in air as a function of the relative humidity

• Dominik J. Kirpal,
• Korbinian Pürckhauer,
• Alfred J. Weymouth and
• Franz J. Giessibl

Beilstein J. Nanotechnol. 2019, 10, 2084–2093, doi:10.3762/bjnano.10.203

• force microscopy; material transport; relative humidity; Introduction Defining surface properties under ambient conditions is challenging as they are heavily influenced by the environment. In general, there are various contributing factors such as temperature, air pressure and air composition

Nanostructured and oriented metal–organic framework films enabling extreme surface wetting properties

• Andre Mähringer,
• Julian M. Rotter and
• Dana D. Medina

Beilstein J. Nanotechnol. 2019, 10, 1994–2003, doi:10.3762/bjnano.10.196

• a large glass substrate allowed for the realization of an efficient, transparent, antifog coating, enabling a clear view even at extreme temperature gaps up to ≈120 °C. This work illustrates the strong link between MOF film morphology and surface properties based on these framework materials

• , S5.7, Supporting Information File 1). Strikingly, we observed complete water spreading on the M-CAT-1 films and a WCA of 0° for both films, thus these surfaces can be considered superhydrophilic (Figure 3D and S5.5, Supporting Information File 1). These observed surface properties were further

• contact with the surface (see Figure S5.7, Supporting Information File 1). These surface properties resemble those of surface designs found in nature. For example, referring to marine life, fish scales in air show an amphiphilic behavior due to their high surface energy, but under water they turn

Kelvin probe force microscopy work function characterization of transition metal oxide crystals under ongoing reduction and oxidation

• Dominik Wrana,
• Karol Cieślik,
• Wojciech Belza,
• Christian Rodenbücher,
• Krzysztof Szot and
• Franciszek Krok

Beilstein J. Nanotechnol. 2019, 10, 1596–1607, doi:10.3762/bjnano.10.155

• splitting [1][44]. For industrial uses, the samples have to be exposed to ambient conditions, therefore it is necessary to investigate the impact of air exposure on electronic surface properties. Moreover, transition metal oxides are often regarded as promising materials for sensing applications, due to the

Synthesis of P- and N-doped carbon catalysts for the oxygen reduction reaction via controlled phosphoric acid treatment of folic acid

• Rieko Kobayashi,
• Takafumi Ishii,
• Yasuo Imashiro and
• Jun-ichi Ozaki

Beilstein J. Nanotechnol. 2019, 10, 1497–1510, doi:10.3762/bjnano.10.148

• ). Surface properties of H- and P-type precursors (for the naming scheme of the samples see section “Experimental”). Distribution of the N species in H-type and P-type precursors. BET-SSAs and XPS-determined elemental surface compositions of HH- and PH-series carbon materials. Distribution of N-species in HH

Warped graphitic layers generated by oxidation of fullerene extraction residue and its oxygen reduction catalytic activity

• Machiko Takigami,
• Rieko Kobayashi,
• Takafumi Ishii,
• Yasuo Imashiro and
• Jun-ichi Ozaki

Beilstein J. Nanotechnol. 2019, 10, 1391–1400, doi:10.3762/bjnano.10.137

• equation. The decrease in the heat of adsorption activated the adsorbed state of oxygen molecules. However, lowering the heat too much led to a small interaction between the adsorbent and the adsorbate (i.e., less activation). Further evidence for the changes in the surface properties due to WGL exposure

A biomimetic nanofluidic diode based on surface-modified polymeric carbon nitride nanotubes

• Kai Xiao,
• Baris Kumru,
• Lu Chen,
• Lei Jiang,
• Bernhard V. K. J. Schmidt and
• Markus Antonietti

Beilstein J. Nanotechnol. 2019, 10, 1316–1323, doi:10.3762/bjnano.10.130

• transportation controlled by surface charges in carbon nitride nanotubes (black squares). The red curve shows the data of the bulk solution (red curve). (a) Scheme of the unilateral modification process and surface properties after modification. (b) The SEM view and corresponding elemental mapping (C, N, S) of

Multicomponent bionanocomposites based on clay nanoarchitectures for electrochemical devices

• Giulia Lo Dico,
• Bernd Wicklein,
• Lorenzo Lisuzzo,
• Giuseppe Lazzara,
• Pilar Aranda and
• Eduardo Ruiz-Hitzky

Beilstein J. Nanotechnol. 2019, 10, 1303–1315, doi:10.3762/bjnano.10.129

• therefore assessed by the van der Pauw method based on the four-point technique [26]. This method is useful to accurately measure the surface properties of a sample of arbitrary shape. Figure 4C displays the in-plane electrical conductivity of the films as a function of the MWCNT content (composition of

Alloyed Pt₃M (M = Co, Ni) nanoparticles supported on S- and N-doped carbon nanotubes for the oxygen reduction reaction

• Stéphane Louisia,
• Yohann R. J. Thomas,
• Pierre Lecante,
• Marie Heitzmann,
• M. Rosa Axet,
• Pierre-André Jacques and
• Philippe Serp

Beilstein J. Nanotechnol. 2019, 10, 1251–1269, doi:10.3762/bjnano.10.125

• carbon materials. Several CNT materials have been synthetized, fully characterized (structural and surface properties) and used as catalyst supports. CNT-supported bimetallic Pt3Co or Pt3Ni NPs were synthetized. To evaluate catalyst performance, electrochemical characterization was performed using a

Playing with covalent triazine framework tiles for improved CO₂ adsorption properties and catalytic performance

• Giulia Tuci,
• Andree Iemhoff,
• Housseinou Ba,
• Lapo Luconi,
• Andrea Rossin,
• Vasiliki Papaefthimiou,
• Regina Palkovits,
• Jens Artz,
• Cuong Pham-Huu and
• Giuliano Giambastiani

Beilstein J. Nanotechnol. 2019, 10, 1217–1227, doi:10.3762/bjnano.10.121

• ][40][41][42][43][44]. Most importantly, the rational balance between morphological and basic material surface properties has been claimed to control the catalyst stability on stream: the higher the “chemically accessible” surface basicity, the lower the sample deactivation/passivation due to the

• performance of selected CTFs was the result of a compromise between morphological and accessible basic surface properties of the samples. In particular, the higher the chemically accessible basic surface of the catalytic materials, the higher their stability (as catalysts) on stream. Indeed, from the

• catalyst surface. The higher the basic surface properties of the CTF, the higher the desorption rate of reagents and products and the higher the catalyst lifetime on stream. This evidence is in line with other findings from the literature where basic properties of the material are crucial in preventing the

Photoactive nanoarchitectures based on clays incorporating TiO₂ and ZnO nanoparticles

• Eduardo Ruiz-Hitzky,
• Pilar Aranda,
• Marwa Akkari,
• Nithima Khaorapapong and
• Makoto Ogawa

Beilstein J. Nanotechnol. 2019, 10, 1140–1156, doi:10.3762/bjnano.10.114

• important to control the synthesis procedures in order to obtain the desired surface properties of the NPs, as well as suitable size and shape and nanopore characteristics in the resulting pillared layered structures. The formation of house-of-cards-like structures during the preparation of ZnO NPs in the

Fe₃O₄ nanoparticles as a saturable absorber for giant chirped pulse generation

• Ji-Shu Liu,
• Xiao-Hui Li,
• Abdul Qyyum,
• Yi-Xuan Guo,
• Tong Chai,
• Hua Xu and
• Jie Jiang

Beilstein J. Nanotechnol. 2019, 10, 1065–1072, doi:10.3762/bjnano.10.107

• . Conclusion In summary, FONPs prepared via a sol–hydrothermal method were successfully used as a SA to construct a high-performance fiber laser. The surface properties, molecular vibration, structure and composition of the FONPs were systemically studied using SEM, TEM, HR-TEM, EDS, Raman spectra, XRD and UV

Tailoring the stability/aggregation of one-dimensional TiO₂(B)/titanate nanowires using surfactants

• Atiđa Selmani,
• Johannes Lützenkirchen,
• Kristina Kučanda,
• Dario Dabić,
• Engelbert Redel,
• Ida Delač Marion,
• Damir Kralj,
• Darija Domazet Jurašin and
• Maja Dutour Sikirić

Beilstein J. Nanotechnol. 2019, 10, 1024–1037, doi:10.3762/bjnano.10.103

• behavior. In order to gain more insight into changes in the surface properties after surfactant adsorption on the TNW surface, a surface complexation model was employed. With this first attempt to quantify the contribution of the surfactant structure on the adsorption equilibrium according to the observed

• concentrations of the cationic monomeric DATB and corresponding gemini 12-2-12 surfactants (Figure S1, Supporting Information File 1) were chosen as a tool to modify the TNW surface properties. Effect of DTAB concentration: The variation of dh and the zeta potential in TNW/DTAB systems at three TNW mass