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Search for "accumulation" in Full Text gives 353 result(s) in Beilstein Journal of Nanotechnology. Showing first 200.

Incorporation of doxorubicin in different polymer nanoparticles and their anticancer activity

  • Sebastian Pieper,
  • Hannah Onafuye,
  • Dennis Mulac,
  • Jindrich Cinatl Jr.,
  • Mark N. Wass,
  • Martin Michaelis and
  • Klaus Langer

Beilstein J. Nanotechnol. 2019, 10, 2062–2072, doi:10.3762/bjnano.10.201

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  • . However, the therapeutic window is small, and anticancer therapies are typically associated with severe side-effects [2][3]. One strategy to develop more effective cancer therapies is to use nano-sized drug delivery systems that mediate a more specific tumour accumulation of transported drugs. Tumour
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Published 29 Oct 2019

Synthesis of highly active ETS-10-based titanosilicate for heterogeneously catalyzed transesterification of triglycerides

  • Muhammad A. Zaheer,
  • David Poppitz,
  • Khavar Feyzullayeva,
  • Marianne Wenzel,
  • Jörg Matysik,
  • Radomir Ljupkovic,
  • Aleksandra Zarubica,
  • Alexander A. Karavaev,
  • Andreas Pöppl,
  • Roger Gläser and
  • Muslim Dvoyashkin

Beilstein J. Nanotechnol. 2019, 10, 2039–2061, doi:10.3762/bjnano.10.200

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Published 28 Oct 2019

Gold-coated plant virus as computed tomography imaging contrast agent

  • Alaa A. A. Aljabali,
  • Mazhar S. Al Zoubi,
  • Khalid M. Al-Batanyeh,
  • Ali Al-Radaideh,
  • Mohammad A. Obeid,
  • Abeer Al Sharabi,
  • Walhan Alshaer,
  • Bayan AbuFares,
  • Tasnim Al-Zanati,
  • Murtaza M. Tambuwala,
  • Naveed Akbar and
  • David J. Evans

Beilstein J. Nanotechnol. 2019, 10, 1983–1993, doi:10.3762/bjnano.10.195

Graphical Abstract
  • noise [27]. The accumulation of such concentration of the contrast agent is very difficult [28]. Therefore, the need to develop different forms on nanoparticles that are densely loaded with CT contrast agents for use in clinical settings will be of great value. The work reported here explores the
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Published 07 Oct 2019

Magnetic properties of biofunctionalized iron oxide nanoparticles as magnetic resonance imaging contrast agents

  • Natalia E. Gervits,
  • Andrey A. Gippius,
  • Alexey V. Tkachev,
  • Evgeniy I. Demikhov,
  • Sergey S. Starchikov,
  • Igor S. Lyubutin,
  • Alexander L. Vasiliev,
  • Vladimir P. Chekhonin,
  • Maxim A. Abakumov,
  • Alevtina S. Semkina and
  • Alexander G. Mazhuga

Beilstein J. Nanotechnol. 2019, 10, 1964–1972, doi:10.3762/bjnano.10.193

Graphical Abstract
  • ZF-NMR spectra were obtained by integration over the spin echo magnitude envelope in the time domain at a given frequency and averaging over the scan accumulation number. Due to the low natural abundance of the 57Fe isotope (2.19%), a relatively large amount (about 1.5 g) of powder Fe nanoparticles
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Published 02 Oct 2019

Synthesis and potent cytotoxic activity of a novel diosgenin derivative and its phytosomes against lung cancer cells

  • Liang Xu,
  • Dekang Xu,
  • Ziying Li,
  • Yu Gao and
  • Haijun Chen

Beilstein J. Nanotechnol. 2019, 10, 1933–1942, doi:10.3762/bjnano.10.189

Graphical Abstract
  • . The results showed that the addition of Di and P2 decreased the particle size of lipid nanoparticles. Particle sizes of 100 nm diameter or less will be beneficial to the blood circulation and tumor accumulation [33]. Numerous studies have shown that cholesterol is crucial for the structural stability
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Published 24 Sep 2019

Charge-transfer interactions between fullerenes and a mesoporous tetrathiafulvalene-based metal–organic framework

  • Manuel Souto,
  • Joaquín Calbo,
  • Samuel Mañas-Valero,
  • Aron Walsh and
  • Guillermo Mínguez Espallargas

Beilstein J. Nanotechnol. 2019, 10, 1883–1893, doi:10.3762/bjnano.10.183

Graphical Abstract
  • ). Blue and yellow regions indicate charge depletion and accumulation, respectively. a) TDDFT absorption spectra calculated at the CAM-B3LYP/6-31G** level for host–guest C60@TTFTB (including vertical excitation energies), TTFTB ligand, and fullerene C60 (singlets and triplet energies). b) Monoelectronic
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Published 18 Sep 2019

Fabrication and characterization of Si1−xGex nanocrystals in as-grown and annealed structures: a comparative study

  • Muhammad Taha Sultan,
  • Adrian Valentin Maraloiu,
  • Ionel Stavarache,
  • Jón Tómas Gudmundsson,
  • Andrei Manolescu,
  • Valentin Serban Teodorescu,
  • Magdalena Lidia Ciurea and
  • Halldór Gudfinnur Svavarsson

Beilstein J. Nanotechnol. 2019, 10, 1873–1882, doi:10.3762/bjnano.10.182

Graphical Abstract
  • of devices containing such structures [32]. A comparison is made to present the effect of SiGe thickness on strain accumulation in NCs and demonstrate the effectiveness of mild thermal exposure, applicable to structures prone to decomposition at elevated temperatures. Results and Discussion The
  • internal defects. The formation or modification of the planar morphology of the 20 nm SiGe layer is expected to be due to accumulation of strain exerted by the SiO2 matrix, which has been relaxed by forming corrugated edges of the SiGe film (Figure 4a and Figure 5). In contrast, for the thicker SiGe films
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Published 17 Sep 2019

Engineered superparamagnetic iron oxide nanoparticles (SPIONs) for dual-modality imaging of intracranial glioblastoma via EGFRvIII targeting

  • Xianping Liu,
  • Chengjuan Du,
  • Haichun Li,
  • Ting Jiang,
  • Zimiao Luo,
  • Zhiqing Pang,
  • Daoying Geng and
  • Jun Zhang

Beilstein J. Nanotechnol. 2019, 10, 1860–1872, doi:10.3762/bjnano.10.181

Graphical Abstract
  • -EGFRvIII cell inoculation, the glioblastoma-bearing mice were randomly divided into 2 groups (NP and PNP group, n = 4). The accumulation of NPs and PNPs in the tumor tissue of glioblastoma-bearing mice was assessed as formerly described [42]. The mice were injected with Cy7.5-labeled NPs or PNPs at a dose
  • observed to be much stronger over the NP group (Figure 4a). The flow cytometry results further indicated that the accumulation of PNPs in U87MG-EGFRvIII cells was about 2.3-fold that of the NPs as shown in Figure 4b. In contrast, after incubation with NPs and PNPs for 2 h, there was no significant
  • PEPHC1 peptide conjugation greatly enhanced PNP accumulation in U87MG-EGFRvIII tumors (Figure 7a and 7b). For the biodistribution study, similar to other drug delivery systems based on tumor-targeting nanoparticles [45][46][47], both PNP and NP nanoprobes were found distributed in other major organs
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Published 11 Sep 2019

Prestress-loading effect on the current–voltage characteristics of a piezoelectric p–n junction together with the corresponding mechanical tuning laws

  • Wanli Yang,
  • Shuaiqi Fan,
  • Yuxing Liang and
  • Yuantai Hu

Beilstein J. Nanotechnol. 2019, 10, 1833–1843, doi:10.3762/bjnano.10.178

Graphical Abstract
  • . The accumulation of minority carriers there will give rise to gradients of NEMC, which stimulates diffusion of NEMC departing from the two boundaries into the zones outside the SCZ and causes a positive current; a reverse-bias voltage increases the potential barrier such that minority carriers at the
  • . The opposite happens under tensile loading. The distributions of NEMC and their accumulation at the SCZ boundaries are shown for different compressive loadings in Figure 4b and for different tensile loadings in Figure 4c, under a forward-bias voltage of V = 0.05 V. It follows from Figure 4 that
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Published 06 Sep 2019

Toxicity and safety study of silver and gold nanoparticles functionalized with cysteine and glutathione

  • Barbara Pem,
  • Igor M. Pongrac,
  • Lea Ulm,
  • Ivan Pavičić,
  • Valerije Vrček,
  • Darija Domazet Jurašin,
  • Marija Ljubojević,
  • Adela Krivohlavek and
  • Ivana Vinković Vrček

Beilstein J. Nanotechnol. 2019, 10, 1802–1817, doi:10.3762/bjnano.10.175

Graphical Abstract
  • Ag L−1). The behavior of GSH AuNPs deviates considerably from the others and did not show any significant change in the side scattered light (SSC) ratio even at the highest dose applied, indicating no cell accumulation. The flow cytometry results on NP uptake were confirmed by visualization performed
  • using confocal laser scanning microscopy (CLSM) in the reflection contrast mode. In cells treated with CYS-AgNPs, GSH-AgNPs and CYS-AuNPs, accumulated NPs were clearly visible intracellularly, while it was not possible to detect such accumulation in the case of treatment with GSH-AuNPs (see Figure 5 and
  • reticuloendothelial system (RES) observed in these studies, which demonstrated that GSH played a protective role for AuNP-based theranostic systems against RES accumulation. Moreover, the conducted pharmacokinetic studies revealed that the use of GSH for the preparation of small AuNPs enhance tumor retention time
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Published 02 Sep 2019

Upcycling of polyurethane waste by mechanochemistry: synthesis of N-doped porous carbon materials for supercapacitor applications

  • Christina Schneidermann,
  • Pascal Otto,
  • Desirée Leistenschneider,
  • Sven Grätz,
  • Claudia Eßbach and
  • Lars Borchardt

Beilstein J. Nanotechnol. 2019, 10, 1618–1627, doi:10.3762/bjnano.10.157

Graphical Abstract
  • ][4][5]. So far, different recycling techniques have been devised to counteract environmental pollution through accumulation of plastic waste. Especially, the recovery of PE and PP, as well as depolymerization processes for PET and the reprocessing of PVC by crushing and melting in conversion systems
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Published 06 Aug 2019

High-temperature resistive gas sensors based on ZnO/SiC nanocomposites

  • Vadim B. Platonov,
  • Marina N. Rumyantseva,
  • Alexander S. Frolov,
  • Alexey D. Yapryntsev and
  • Alexander M. Gaskov

Beilstein J. Nanotechnol. 2019, 10, 1537–1547, doi:10.3762/bjnano.10.151

Graphical Abstract
  • (Figure 10). The estimated CBM position of wurtzite ZnO is 0.46 eV lower than that of 3C-SiC. The interface of an n–n junction transfers electrons into the lower energy conduction band [35]. The “accumulation layer” formed in this way can be depleted by subsequent oxygen adsorption on an enriched electron
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Published 26 Jul 2019

Magnetic segregation effect in liquid crystals doped with carbon nanotubes

  • Danil A. Petrov,
  • Pavel K. Skokov,
  • Alexander N. Zakhlevnykh and
  • Dmitriy V. Makarov

Beilstein J. Nanotechnol. 2019, 10, 1464–1474, doi:10.3762/bjnano.10.145

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  • leads to the accumulation of CNTs in the middle of the layer, leaving the boundary regions of the layer to be depleted in CNTs. At κ = 0.5 (Figure 6b), the redistribution of CNTs with increasing field is not so significant. Interestingly, in this case, the CNT volume fraction g(ζ) ≈ 1 at two spatial
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Published 22 Jul 2019

Direct observation of oxygen-vacancy formation and structural changes in Bi2WO6 nanoflakes induced by electron irradiation

  • Hong-long Shi,
  • Bin Zou,
  • Zi-an Li,
  • Min-ting Luo and
  • Wen-zhong Wang

Beilstein J. Nanotechnol. 2019, 10, 1434–1442, doi:10.3762/bjnano.10.141

Graphical Abstract
  • will be induced by the accumulation of secondary electrons and Auger electrons in the irradiation region [28][29]. The charged ions in the crystal will be displaced, and ionic bonds can be broken when the induced electric field, which can be enhanced with the increase of the irradiation time, is
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Published 18 Jul 2019

Enhanced inhibition of influenza virus infection by peptide–noble-metal nanoparticle conjugates

  • Zaid K. Alghrair,
  • David G. Fernig and
  • Bahram Ebrahimi

Beilstein J. Nanotechnol. 2019, 10, 1038–1047, doi:10.3762/bjnano.10.104

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  • reduce the potential for accumulation of nanoparticles in the body during repeated use of a FluPep-nanoparticle therapeutic. The pulmonary route to deliver drugs against respiratory infections is well established, so delivery of functionalised nanoparticles against flu viruses is highly feasible
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Published 14 May 2019
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  • concentrated on a surface or in a well-defined volume, SERS tags allow for the collection of an intense Raman signal revealing the presence of the targeted molecule. Analyte accumulation on a surface may happen, for instance, through a sandwich configuration as in the well-established enzyme-linked
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Published 10 May 2019

Serum type and concentration both affect the protein-corona composition of PLGA nanoparticles

  • Katrin Partikel,
  • Robin Korte,
  • Dennis Mulac,
  • Hans-Ulrich Humpf and
  • Klaus Langer

Beilstein J. Nanotechnol. 2019, 10, 1002–1015, doi:10.3762/bjnano.10.101

Graphical Abstract
  • numerous protein bands ranging from 29 to 212 kDa. An accumulation of protein bands occurs between 43 and 118 kDa and a sharply defined band is located at the top of the gel above 118 kDa. Besides, three distinctive bands appear around 29 kDa. Figure 3A clearly shows that the composition of the hard corona
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Published 06 May 2019

Electronic and magnetic properties of doped black phosphorene with concentration dependence

  • Ke Wang,
  • Hai Wang,
  • Min Zhang,
  • Yan Liu and
  • Wei Zhao

Beilstein J. Nanotechnol. 2019, 10, 993–1001, doi:10.3762/bjnano.10.100

Graphical Abstract
  • shown in Figure 6. In Figure 6, charge accumulation is depicted by the gold isosurface, while the cyan isosurface represents charge depletion. The isosurfaces are separated by ±0.04 e/Å3. From Figure 6, one can find clearly that the Si atom donates electrons to three neighboring phosphorus atoms. The S
  • phosphorene with (a) 2 × 2 × 1, (b) 3 × 3 × 1, (c) 4 × 4 × 1, and (d) 5 × 5 × 1 supercell, respectively; (e–h) CDDs of S-doped phosphorene with (e) 2 × 2 × 1, (f) 3 × 3 × 1, (g) 4 × 4 × 1 and (h) 5 × 5 × 1 supercells, respectively. The gold (cyan) isosurfaces represent charge accumulation (depletion), and the
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Published 02 May 2019

Effects of gold and PCL- or PLLA-coated silica nanoparticles on brain endothelial cells and the blood–brain barrier

  • Aniela Bittner,
  • Angélique D. Ducray,
  • Hans Rudolf Widmer,
  • Michael H. Stoffel and
  • Meike Mevissen

Beilstein J. Nanotechnol. 2019, 10, 941–954, doi:10.3762/bjnano.10.95

Graphical Abstract
  • et al. found a size-dependent rapid accumulation of Au-NPs in rBMECs within 30 min [19]. In agreement with the co-localization of Au-NPs with heterolysosomes found in our study, Au-NPs of the same size (80 nm) were shown to be taken up by HUVECs, localizing in endosomes and lysosomes [33]. Besides
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Published 25 Apr 2019

The systemic effect of PEG-nGO-induced oxidative stress in vivo in a rodent model

  • Qura Tul Ain,
  • Samina Hyder Haq,
  • Abeer Alshammari,
  • Moudhi Abdullah Al-Mutlaq and
  • Muhammad Naeem Anjum

Beilstein J. Nanotechnol. 2019, 10, 901–911, doi:10.3762/bjnano.10.91

Graphical Abstract
  • nGO in organs including lung, liver, and spleen and promoted its clearance from these organs [28]. Zhang et al. treated a tumour with a chemo-photothermal therapy based on PEG-GO [29]. The safety and tumour accumulation of PEG-GO has been reported by Miao and co-workers [30]. Functionalized PEG-nGO
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Published 18 Apr 2019

Novel reversibly switchable wettability of superhydrophobic–superhydrophilic surfaces induced by charge injection and heating

  • Xiangdong Ye,
  • Junwen Hou and
  • Dongbao Cai

Beilstein J. Nanotechnol. 2019, 10, 840–847, doi:10.3762/bjnano.10.84

Graphical Abstract
  • accumulation of solid–liquid interfacial charges, we discovered a phenomenon where charge injection and accumulation at the solid surface results in a sharp increase in wettability. The wettability of a sprayed SiO2 nanoparticle coating on a glass slide was shown to change from superhydrophobic to
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Published 10 Apr 2019

Tungsten disulfide-based nanocomposites for photothermal therapy

  • Tzuriel Levin,
  • Hagit Sade,
  • Rina Ben-Shabbat Binyamini,
  • Maayan Pour,
  • Iftach Nachman and
  • Jean-Paul Lellouche

Beilstein J. Nanotechnol. 2019, 10, 811–822, doi:10.3762/bjnano.10.81

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  • accumulation effect, but parameters such as nanostructure shape and surface charge are extremely important [33]. A wide range of nanomaterials has been studied for cancer PTT to now, from organic conjugated polymers [34][35], through carbon-based nanomaterials [36][37], to inorganic nanostructures. Within the
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Published 02 Apr 2019

Polydopamine-coated Au nanorods for targeted fluorescent cell imaging and photothermal therapy

  • Boris N. Khlebtsov,
  • Andrey M. Burov,
  • Timofey E. Pylaev and
  • Nikolai G. Khlebtsov

Beilstein J. Nanotechnol. 2019, 10, 794–803, doi:10.3762/bjnano.10.79

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  • fluorescent imaging and plasmonic phothothermal abilities have not been reported previously. The multifunctional nanoparticles were stable in cell buffer, nontoxic and suitable for targeted fluorescent imaging and photothermal therapy of cancer cells. We demonstrate the enhanced accumulation of folate
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Published 01 Apr 2019

The effect of translation on the binding energy for transition-metal porphyrines adsorbed on Ag(111) surface

  • Luiza Buimaga-Iarinca and
  • Cristian Morari

Beilstein J. Nanotechnol. 2019, 10, 706–717, doi:10.3762/bjnano.10.70

Graphical Abstract
  • charge transfer occurs through a whole range of effects, from chemical bonds to Pauli push-back of electrons from the close shells and from the surface [69][70][71]. The accumulation of charge in the region between the molecule and the surface indicates the formation of a chemical bond while a depletion
  • of in the region between the vanadium atom and the silver surface. For MnPP and CoPP, only the spin-down component exhibits bond-like behavior. For the spin-up component a nodal plane for is present between TM atom and silver surface. As discussed above, the accumulation of electrons between two
  • mechanism (see Supporting Information File 1, Figure S5, right). The analysis of the quantity displays shapes specific to a covalent bond, i.e., charge accumulation between the atoms in direct interaction. For one of the two spin components of charge density charge accumulation is present, while there is a
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Published 13 Mar 2019

Ultrathin hydrophobic films based on the metal organic framework UiO-66-COOH(Zr)

  • Miguel A. Andrés,
  • Clemence Sicard,
  • Christian Serre,
  • Olivier Roubeau and
  • Ignacio Gascón

Beilstein J. Nanotechnol. 2019, 10, 654–665, doi:10.3762/bjnano.10.65

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  • , which reveal higher accumulation of material. This was probably formed during film transfer, since the area per molecule at the surface pressure during transfer (0.2 nm2 per molecule) is smaller than the values obtained for self-assembled monolayers (0.25 nm2) of ODP onto mica [56]. The characteristic
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Published 06 Mar 2019
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