Introducing third-generation periodic table descriptors for nano-qRASTR modeling of zebrafish toxicity of metal oxide nanoparticles

• Supratik Kar and
• Siyun Yang

Beilstein J. Nanotechnol. 2024, 15, 1142–1152, doi:10.3762/bjnano.15.93

• development of nanotechnology, more and more MONPs including zinc, iron, titanium, and copper are being explored in therapeutic applications such as drug delivery, bioimaging, biosensing, bioelectronics, and tissue engineering applications [4][5][6]. Simultaneously, many of these particles also presented

Unveiling the potential of alginate-based nanomaterials in sensing technology and smart delivery applications

• Shakhzodjon Uzokboev,
• Khojimukhammad Akhmadbekov,
• Ra’no Nuritdinova,
• Salah M. Tawfik and
• Yong-Ill Lee

Beilstein J. Nanotechnol. 2024, 15, 1077–1104, doi:10.3762/bjnano.15.88

• charge on the polymer. It is critical in enabling quick electron transfer between an enzyme and an electrode surface, triggering the enzyme’s catalytic function for rapid biosensing [100]. Environmental sensing applications One key advantage of using nanosensors in environmental sensing is their ability

• [126]. The biosensing capabilities of alginate-based nanoparticles have been established by several studies. For example, glucose oxidase encapsulated in an alginate biopolymer can detect glucose levels in human blood samples with excellent precision and sensitivity. Similarly, scientists created an

• controlled release of insulin in response to glucose levels. This capability makes them particularly promising for the development of glucose-responsive systems for insulin delivery, which could revolutionize diabetes management [142]. Glucose biosensing can be performed by two methods, namely, enzymatic and

Recent progress on field-effect transistor-based biosensors: device perspective

• Billel Smaani,
• Fares Nafa,
• Mohamed Salah Benlatrech,
• Ismahan Mahdi,
• Hamza Akroum,
• Mohamed walid Azizi,
• Khaled Harrar and
• Sayan Kanungo

Beilstein J. Nanotechnol. 2024, 15, 977–994, doi:10.3762/bjnano.15.80

• the electrical characteristics of the device. In this context, due to diversities in the transduction and applications of FET-biosensors, the primary design improvisation involves novel device architectures for FET dedicated to biosensing applications. Therefore, an extensive and systematic review on

• hybrid partially gated design is reported as an exceptional device allowing digital gates with biosensing integration. Also, a hardware description language (Verilog-A) has been used for the modeling of each device structure to be incorporated into various system designs via electronic design automation

• signal conditioning and biosensing have been implemented, such as the pseudo-differential amplifier and ring oscillator circuits. It has been demonstrated that the FinFET-based sensing amplifier exhibits a readout sensitivity that is at least ten times higher than that of individually addressable single

Metal-organic framework-based nanomaterials as opto-electrochemical sensors for the detection of antibiotics and hormones: A review

• Akeem Adeyemi Oladipo,
• Saba Derakhshan Oskouei and
• Mustafa Gazi

Beilstein J. Nanotechnol. 2023, 14, 631–673, doi:10.3762/bjnano.14.52

SERS performance of GaN/Ag substrates fabricated by Ag coating of GaN platforms

• Magdalena A. Zając,
• Bogusław Budner,
• Malwina Liszewska,
• Bartosz Bartosewicz,
• Łukasz Gutowski,
• Jan L. Weyher and
• Bartłomiej J. Jankiewicz

Beilstein J. Nanotechnol. 2023, 14, 552–564, doi:10.3762/bjnano.14.46

• use in various applications, including biosensing and bioanalysis [4][5][6][7], and many defense and homeland security applications [8][9][10], such as forensic science [11] or detection of hazardous materials [12][13][14][15][16]. Any SERS technique application requires efficient, reproducible, and

Observation of multiple bulk bound states in the continuum modes in a photonic crystal cavity

• Rui Chen,
• Yi Zheng,
• Xingyu Huang,
• Qiaoling Lin,
• Chaochao Ye,
• Meng Xiong,
• Martijn Wubs,
• Yungui Ma,
• Minhao Pu and
• Sanshui Xiao

Beilstein J. Nanotechnol. 2023, 14, 544–551, doi:10.3762/bjnano.14.45

• confinement in a relatively simple way. Such strong resonances endow PhC-based BIC devices with a strong enhancement of light–matter interaction, indicating great potential for applications in ultrasensitive molecular fingerprint detection [12][13][35], hyperspectral biosensing imaging [36], novel flat light

A mid-infrared focusing grating coupler with a single circular arc element based on germanium on silicon

• Xiaojun Zhu,
• Shuai Li,
• Ang Sun,
• Yongquan Pan,
• Wen Liu,
• Yue Wu,
• Guoan Zhang and
• Yuechun Shi

Beilstein J. Nanotechnol. 2023, 14, 478–484, doi:10.3762/bjnano.14.38

• proposed MIR grating coupler [14]. Finally, the transmission characteristics of the output fiber can be detected using an optical spectrum analyzer. There is a wide range of sensors for applications in, for example, biosensing, healthcare, disease detection, and gas detection. Therefore, research on those

Gap-directed chemical lift-off lithographic nanoarchitectonics for arbitrary sub-micrometer patterning

• Chang-Ming Wang,
• Hong-Sheng Chan,
• Chia-Li Liao,
• Che-Wei Chang and
• Wei-Ssu Liao

Beilstein J. Nanotechnol. 2023, 14, 34–44, doi:10.3762/bjnano.14.4

• fabricated with inexpensive photomasks. With this technology, we foresee that the straightforward generation of versatile nanoscale patterns can further push the boundaries of CLL, and expand its applications in solving conventional biosensing, nanoelectronics, and semiconductor problems. Visualization of

Rapid and sensitive detection of box turtles using an electrochemical DNA biosensor based on a gold/graphene nanocomposite

• Abu Hashem,
• M. A. Motalib Hossain,
• Ab Rahman Marlinda,
• Mohammad Al Mamun,
• Khanom Simarani and
• Mohd Rafie Johan

Beilstein J. Nanotechnol. 2022, 13, 1458–1472, doi:10.3762/bjnano.13.120

• shown to have synergistic benefits [36][48]. As a result, there are good reasons to believe that combining Gr and AuNPs in biosensing will result in a synergistic impact on electro-oxidation [30][37]. Considering these, we hypothesised that a combination of Gr and AuNPs would increase the detection

• experiment, pH 7.4 was chosen, which is close to physiological pH, and a similar pH value was reported by Kusnin et al. [57] in hybridisation biosensing experiments. Selectivity of the electrochemical biosensor Electrodes with hybridised DNA were incubated in MB for 30 min, washed with deionised water, and

• -based biosensing [65]. The Gooding Group published a method for measuring DNA hybridisation by voltammetry on gold electrodes using methylene blue as an intercalator and a self-assembled alkanethiol monolayer. N-hydroxysulfosuccinimide (NHS) and N-(3-dimethylamino) propyl-N-ethylcarbodiimide

Recent advances in green carbon dots (2015–2022): synthesis, metal ion sensing, and biological applications

• Aisha Kanwal,
• Naheed Bibi,
• Sajjad Hyder,
• Arif Muhammad,
• Hao Ren,
• Jiangtao Liu and
• Zhongli Lei

Beilstein J. Nanotechnol. 2022, 13, 1068–1107, doi:10.3762/bjnano.13.93

• applications [36], tumor marker detection [37], bioanalytical studies [38], biomedical [39][40] and biotechnological applications [3], biosensing and bioimaging [31][32], and fluorescence [41] and photoluminescence processes [42]. Many reviews about CDs obtained from natural resources have been published

• properties of CDs. By introducing electrons into CDs and altering the internal electronic states, nitrogen atoms significantly enhance the fluorescence characteristics of these molecules. The N-CDs produced perform exceptionally well in biomedical applications, including bioimaging and biosensing. A huge

DNA aptamer selection and construction of an aptasensor based on graphene FETs for Zika virus NS1 protein detection

• Nathalie B. F. Almeida,
• Thiago A. S. L. Sousa,
• Viviane C. F. Santos,
• Camila M. S. Lacerda,
• Thais G. Silva,
• Rafaella F. Q. Grenfell,
• Flavio Plentz and
• Antero S. R. Andrade

Beilstein J. Nanotechnol. 2022, 13, 873–881, doi:10.3762/bjnano.13.78

• (specificity assay), and biosensing with functionalized graphene devices. To the best of our knowledge, our work is the first to demonstrate aptamer selection for ZIKV NS1 and, simultaneously, its application on a biosensing platform, creating possible routes for the future development of point-of-care

Optimizing PMMA solutions to suppress contamination in the transfer of CVD graphene for batch production

• Chun-Da Liao,
• Andrea Capasso,
• Tiago Queirós,
• Telma Domingues,
• Fatima Cerqueira,
• Nicoleta Nicoara,
• Jérôme Borme,
• Paulo Freitas and
• Pedro Alpuim

Beilstein J. Nanotechnol. 2022, 13, 796–806, doi:10.3762/bjnano.13.70

• process in the mass fabrication of arrays of receded-gate graphene field-effect transistors for biosensing applications. Results and Discussion We transferred graphene by using PMMA with two AMWs (15k and 550k), which were dissolved in anisole at two weight ratios (2 and 4 wt %). PMMA with 950,000 (950k

Recent advances in nanoarchitectures of monocrystalline coordination polymers through confined assembly

• Lingling Xia,
• Qinyue Wang and
• Ming Hu

Beilstein J. Nanotechnol. 2022, 13, 763–777, doi:10.3762/bjnano.13.67

• harsher conditions, such as higher temperatures, and can be released as needed. This finding shows great potential in applications such as nanomedicine, biospecimen preservation, biosensing, and cell and virus manipulation. The related reports have been nicely summarized in a recent review (Figure 3) [105

• . This content is not subject to CC BY 4.0. Monocrystalline coordination polymers encapsulated with bioentities and their applications in nanomedicine, biospecimen preservation, biosensing, and cell and virus manipulation. Figure 3 was reproduced from [105] (© 2021 M. D. Velásquez-Hernández et al

A nonenzymatic reduced graphene oxide-based nanosensor for parathion

• Sarani Sen,
• Anurag Roy,
• Ambarish Sanyal and
• Parukuttyamma Sujatha Devi

Beilstein J. Nanotechnol. 2022, 13, 730–744, doi:10.3762/bjnano.13.65

• nonenzymatic approach through electrochemical nanosensing which can also be used in other biosensing applications. Experimental Chemicals The chemicals used in this work are summarized in Supporting Information File 1, Table S1. Sodium dihydrogen phosphate was used to prepare phosphate buffer saline (pH 4.6

Detection and imaging of Hg(II) in vivo using glutathione-functionalized gold nanoparticles

• Gufeng Li,
• Shaoqing Li,
• Rui Wang,
• Min Yang,
• Lizhu Zhang,
• Yanli Zhang,
• Wenrong Yang and
• Hongbin Wang

Beilstein J. Nanotechnol. 2022, 13, 549–559, doi:10.3762/bjnano.13.46

• incubated in HeLa cells. We expect that this new system based on the molecular regulation of functionalized GNPs can have potential applications in pollution monitoring, biosensing, and cellular imaging. Results and Discussion Synthesis and spectral signature of GNPs-GSH-Rh6G2 As shown in Figure 1a, 13 nm

Nanogenerator-based self-powered sensors for data collection

• Yicheng Shao,
• Maoliang Shen,
• Yuankai Zhou,
• Xin Cui,
• Lijie Li and
• Yan Zhang

Beilstein J. Nanotechnol. 2021, 12, 680–693, doi:10.3762/bjnano.12.54

• ://creativecommons.org/licenses/by/4.0). (b) Implantable skin-like glucometer implanted in a mouse and the voltage output of the device under different blood glucose concentrations [31]. (c) The output voltage performance of sweat-evaporation-biosensing sensors in different concentrations of lactic acid [37]. Figure 4c

• ,d was adapted from [37], Nano Energy, vol. 59, by H. Guan, T. Zhong, H. He, T. Zhao, L. Xing, Y. Zhang, X. Xue, “A self-powered wearable sweat-evaporation-biosensing analyzer for building sports big data”, pages no. 754–761, Copyright (2019), with permission from Elsevier. (d) Real-time voltage

• output generated by the sweat-evaporation-biosensing sensor when three people are cycling [37]. (e) The FBFC converts glucose to produce DC output, the FNG produces AC output from the same periodic pressure, and the hybrid system output of FBFC and FNG in series [35]. Figure 4e,f was reproduced from [35

Fate and transformation of silver nanoparticles in different biological conditions

• Barbara Pem,
• Marija Ćurlin,
• Darija Domazet Jurašin,
• Valerije Vrček,
• Rinea Barbir,
• Vedran Micek,
• Raluca M. Fratila,
• Jesus M. de la Fuente and
• Ivana Vinković Vrček

Beilstein J. Nanotechnol. 2021, 12, 665–679, doi:10.3762/bjnano.12.53

• diagnostics (biosensing, bioimaging) [2][3]. Such prevalence has raised concerns among the regulatory authorities about the safety of AgNPs for humans due to significant lack of relevant regulatory data. Thus, the Scientific Committee on Consumer Safety (SCCS) highlighted in its final Opinion on Colloidal

A review of defect engineering, ion implantation, and nanofabrication using the helium ion microscope

• Frances I. Allen

Beilstein J. Nanotechnol. 2021, 12, 633–664, doi:10.3762/bjnano.12.52

On the stability of microwave-fabricated SERS substrates – chemical and morphological considerations

• Limin Wang,
• Aisha Adebola Womiloju,
• Christiane Höppener,
• Ulrich S. Schubert and
• Stephanie Hoeppener

Beilstein J. Nanotechnol. 2021, 12, 541–551, doi:10.3762/bjnano.12.44

• in chemical and bioanalytical research [1][2]. Its application in chemistry, biosensing, materials science, engineering, and medical diagnostics was successfully introduced and can provide valuable information [1][2][3][4]. Since it was discovered in 1974 by Fleischmann et al. that the intensity of

Effect of different silica coatings on the toxicity of upconversion nanoparticles on RAW 264.7 macrophage cells

• Cynthia Kembuan,
• Helena Oliveira and
• Christina Graf

Beilstein J. Nanotechnol. 2021, 12, 35–48, doi:10.3762/bjnano.12.3

• chemical inertness and relatively low toxicity are also claimed advantages [7][10][11]. Due to these unique features, UCNPs have already been used in medical and biological applications, such as multimodal bioimaging, drug delivery, photodynamic therapy, and biosensing [9][12][13][14][15][16][17]. However

Soybean-derived blue photoluminescent carbon dots

• Shanshan Wang,
• Wei Sun,
• Dong-sheng Yang and
• Fuqian Yang

Beilstein J. Nanotechnol. 2020, 11, 606–619, doi:10.3762/bjnano.11.48

• Engineering and Environmental Engineering, Liaoning Shihua University, Fushun, Liaoning, 113001, China 10.3762/bjnano.11.48 Abstract Biomass-derived carbon dots (CDs) are biocompatible and have potential for a variety of applications, including bioimaging and biosensing. In this work, we use ground soybean

• wavelength [7], and low cost [8]. CDs have been considered as a group of important nanomaterials with potential applications in nanotechnology [9], electrocatalysis [10], metal-ion detection [2], thermal sensing [11], drug delivery [12], and biosensing and bioimaging [1]. Several methods are available for

• CDs in bioimaging and biosensing, we synthesize biocompatible CDs from soybean residuals using two strategies. The first strategy uses a one-step HTC process to produce CDs directly from the soybean residuals, and the second one uses multiple steps to produce CDs from the same soybean precursors

Luminescent gold nanoclusters for bioimaging applications

• Nonappa

Beilstein J. Nanotechnol. 2020, 11, 533–546, doi:10.3762/bjnano.11.42

• optoelectronic properties make them suitable for bioimaging and biosensing applications. In this review, an overview of the sensing of pathogens, and of in vitro and in vivo bioimaging using luminescent gold nanoclusters along with the limitations with selected examples are discussed. Keywords: bioimaging

• ; biosensing; gold nanoclusters; immunoassay; luminescence; self-assembly; theranostics; Introduction Imaging methods play a central role in understanding the structural and functional biological processes of biomolecules, cells, tissues, organs, and even entire living organisms [1][2]. The importance of

• been previously summarized in several reports [54][78][79][80][81][82]. This review discusses an overview of the application of gold NCs in biosensing and bioimaging. Importantly, the sensing of pathogenic bacteria and viruses, in vitro imaging of cell lines and in vivo bioimaging using animal models

Multilayer capsules made of weak polyelectrolytes: a review on the preparation, functionalization and applications in drug delivery

• Varsha Sharma and
• Anandhakumar Sundaramurthy

Beilstein J. Nanotechnol. 2020, 11, 508–532, doi:10.3762/bjnano.11.41

• /biopolymer systems in applications such as therapeutics, biosensing, bioimaging, bioreactors, vaccination, tissue engineering and gene delivery. This review gives an emerging outlook on the advantages and unique responsiveness of weak polyelectrolyte based systems that can enable their widespread use in

Using gold nanoparticles to detect single-nucleotide polymorphisms: toward liquid biopsy

• María Sanromán Iglesias and
• Marek Grzelczak

Beilstein J. Nanotechnol. 2020, 11, 263–284, doi:10.3762/bjnano.11.20

• cancer biomarker. We discuss the main mechanisms of the assays that either are assisted by DNA-based molecular machines or by enzymatic reactions, summarize their performance and provide an outlook towards future developments. Keywords: amplification reactions; biomarkers; colorimetric biosensing; gold

• times larger than their physical diameters) [59], and the lack of photobleaching (unlike organic fluorescent dyes and semiconductor nanocrystals) are additional parameters making plasmonic nanocrystals attractive materials for biosensing. Importantly, the position of the plasmon band and its bandwidth

• amplification. Enzyme-free SNP discrimination using gold nanoparticles Although the first works on the selective aggregation of Au@DNA by complementary ssDNA offered a conceptual novelty in the field of biosensing, the simple aggregation of nanoparticles via complementary target DNA suffered from low detection

Molecular architectonics of DNA for functional nanoarchitectures

• Debasis Ghosh,
• Lakshmi P. Datta and
• Thimmaiah Govindaraju

Beilstein J. Nanotechnol. 2020, 11, 124–140, doi:10.3762/bjnano.11.11

• as potential diagnostic or therapeutic (theranostic) nanoagents. Xu and co-workers demonstrated the derivation of a DNA tetrahedral electroluminescence (ECL) biosensor probe for a functional biosensing assay (Figure 3) [69]. The ECL biosensor platform was constructed based on a DNA tetrahedral