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Search for "nanoparticles" in Full Text gives 1217 result(s) in Beilstein Journal of Nanotechnology. Showing first 200.

Supramolecular hydration structure of graphene-based hydrogels: density functional theory, green chemistry and interface application

  • Hon Nhien Le,
  • Duy Khanh Nguyen,
  • Minh Triet Dang,
  • Huyen Trinh Nguyen,
  • Thi Bang Tam Dao,
  • Trung Do Nguyen,
  • Chi Nhan Ha Thuc and
  • Van Hieu Le

Beilstein J. Nanotechnol. 2025, 16, 806–822, doi:10.3762/bjnano.16.61

Graphical Abstract
  • , bandgap energy, and formation energy of the molecular system of bilayer graphene intercalated with a water layer. In the experimental aspect, green chemistry methods were applied for synthesizing GO nanosheets, rice-husk-derived silica gel (SG), nanosilica–zinc hydroxide nanoparticles (SG-ZH), and
  • circular economy [18][19][20][21]. Especially, GO nanosheets decorated with SG-ZH nanoparticles have hydrophilic surfaces to retain hydration layers in the hydrogel structure of the GO-SG-ZH nanocomposite. Hydration layers in the GO-SG-ZH hydrogel also function as lubricants at the nanomaterials interfaces
  • nanosheets, SG nanoparticles, and ZH nanostructures are attractive to water molecules to form hydration shells on the surfaces. In addition to hydration layers, the three-dimensional assembly of graphene-based nanosheets provides high porosity as water reservoirs which supply water to intersheet spacings
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Published 04 Jun 2025

Morphology and properties of pyrite nanoparticles obtained by pulsed laser ablation in liquid and thin films for photodetection

  • Akshana Parameswaran Sreekala,
  • Bindu Krishnan,
  • Rene Fabian Cienfuegos Pelaes,
  • David Avellaneda Avellaneda,
  • Josué Amílcar Aguilar-Martínez and
  • Sadasivan Shaji

Beilstein J. Nanotechnol. 2025, 16, 785–805, doi:10.3762/bjnano.16.60

Graphical Abstract
  • disulfide (FeS2)) nanoparticles (NPs) of different morphologies using pulsed laser ablation in liquid (PLAL) in different organic solvents. The impact of the solvent on the morphological, compositional, and optical properties of the synthesized NPs is investigated by techniques such as transmission electron
  • prepared by PLAL. Keywords: electrophoretic deposition; pulsed laser ablation in liquid; pyrite nanoparticles; self-powered photodetector; spin coating; Introduction Pyrite (FeS2) is one of the earth-abundant and nontoxic semiconductors possessing a promising role in optoelectronic applications. FeS2 has
  • synthesize pyrite nanoparticles in various solvents, including isopropyl alcohol (IPA), dimethyl formamide (DMF), ethanol, methanol, and acetone, using a 532 nm wavelength output from a Nd:YAG laser. Pulsed laser ablation in liquid has been demonstrated as a reliable alternative to conventional chemical
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Published 03 Jun 2025

Changes of structural, magnetic and spectroscopic properties of microencapsulated iron sucrose nanoparticles in saline

  • Sabina Lewińska,
  • Pavlo Aleshkevych,
  • Roman Minikayev,
  • Anna Bajorek,
  • Mateusz Dulski,
  • Krystian Prusik,
  • Tomasz Wojciechowski and
  • Anna Ślawska-Waniewska

Beilstein J. Nanotechnol. 2025, 16, 762–784, doi:10.3762/bjnano.16.59

Graphical Abstract
  • changes upon dissolution in saline were tested. For the undissolved sample, calcium alginate microcapsules with irregular shapes were registered via scanning electron microscopy, inside which core–shell nanoparticles were identified by transmission electron microscopy micrographs. Magnetic studies (DC and
  • completely dissolved sample. Keywords: calcium alginate; dissolution; iron oxyhydroxide nanoparticles; magnetic properties; saline; spectroscopy; Introduction Hematinic are substances such as iron, vitamin B12, and folic acid that are essential in the production of blood [1]. Iron deficiency drugs, which
  • belong to the hematinic category, are a broad class of medical products in which varied iron agents are used, very often in the form of core–shell nanoparticles, where iron ions (in the structure of iron oxide mineral) are concentrated in the core, and the shell is generally composed of carbohydrates
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Published 02 Jun 2025

Serum heat inactivation diminishes ApoE-mediated uptake of D-Lin-MC3-DMA lipid nanoparticles

  • Demian van Straten,
  • Luuk van de Schepop,
  • Rowan Frunt,
  • Pieter Vader and
  • Raymond M. Schiffelers

Beilstein J. Nanotechnol. 2025, 16, 740–748, doi:10.3762/bjnano.16.57

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  • Demian van Straten Luuk van de Schepop Rowan Frunt Pieter Vader Raymond M. Schiffelers CDL Research, University Medical Center Utrecht, Utrecht, The Netherlands 10.3762/bjnano.16.57 Abstract Nanoparticles play a crucial role in drug delivery research. The protein corona that develops on the
  • surface of nanoparticles after administration has garnered substantial attention due to the significant effects it has on their performance. Lipid nanoparticles (LNPs) depend on protein corona formation to mediate their targeting. Such protein–nanoparticle interactions are often initially studied using in
  • inherent limitations of different classes of therapeutics, ranging from small molecule drugs, to biologicals such as proteins and nucleic acids. Nanoparticles can enhance the solubility and stability of their payload, prolong its circulation time, and improve its biodistribution to increase their safety
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Published 30 May 2025

Synthesis of a multicomponent cellulose-based adsorbent for tetracycline removal from aquaculture water

  • Uyen Bao Tran,
  • Ngoc Thanh Vo-Tran,
  • Khai The Truong,
  • Dat Anh Nguyen,
  • Quang Nhat Tran,
  • Huu-Quang Nguyen,
  • Jaebeom Lee and
  • Hai Son Truong-Lam

Beilstein J. Nanotechnol. 2025, 16, 728–739, doi:10.3762/bjnano.16.56

Graphical Abstract
  • significant morphological changes compared to pristine CMC (Figure 2a–c). Specifically, the PGC surface exhibits numerous, uniformly distributed spherical nanoparticles (≈200 nm in diameter), attributed to ZnO nanoparticles. The initial tubular structure of CMC is converted into a film-like structure owing to
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Published 27 May 2025

Efficiency of single-pulse laser fragmentation of organic nutraceutical dispersions in a circular jet flow-through reactor

  • Tina Friedenauer,
  • Maximilian Spellauge,
  • Alexander Sommereyns,
  • Verena Labenski,
  • Tuba Esatbeyoglu,
  • Christoph Rehbock,
  • Heinz P. Huber and
  • Stephan Barcikowski

Beilstein J. Nanotechnol. 2025, 16, 711–727, doi:10.3762/bjnano.16.55

Graphical Abstract
  • yield of submicrometer particles and nanoparticles was quantified using UV–vis extinction spectroscopy, scanning electron microscopy, and analytical centrifugation, while high-performance liquid chromatography determined degradation. We found improved fragmentation efficiency at lower mass
  • ), and laser melting (LML) in liquids are aimed at synthesizing nanoparticles (NPs) from bulk targets (LAL), by downsizing (LFL), or by increasing/reshaping (LML) particle dispersions [1]. On the other hand, pulsed laser defect engineering in liquids (PUDEL) processes involve targeted post-treatment of
  • ) nanoparticles [60]. On the other hand, it has been shown that optical breakdown and the production of ROS are hampered at high nanoparticle concentrations [60], which may be responsible for the low degradation by LFL-generated radicals at high particle mass concentrations. Furthermore, it has to be considered
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Published 26 May 2025

Nanostructured materials characterized by scanning photoelectron spectromicroscopy

  • Matteo Amati,
  • Alexey S. Shkvarin,
  • Alexander I. Merentsov,
  • Alexander N. Titov,
  • María Taeño,
  • David Maestre,
  • Sarah R. McKibbin,
  • Zygmunt Milosz,
  • Ana Cremades,
  • Rainer Timm and
  • Luca Gregoratti

Beilstein J. Nanotechnol. 2025, 16, 700–710, doi:10.3762/bjnano.16.54

Graphical Abstract
  • composition and the surface potential across InP nanowire p–n junctions for individual nanowire devices. InP nanowires were grown on InP(111) substrates by vapor–liquid–solid growth using nanoimprint lithography for generating catalytic Au nanoparticles in a metal–organic vapor phase epitaxy (MOVPE) reactor
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Published 23 May 2025

Aprepitant-loaded solid lipid nanoparticles: a novel approach to enhance oral bioavailability

  • Mazhar Hussain,
  • Muhammad Farooq,
  • Muhammad Asad Saeed,
  • Muhammad Ijaz,
  • Sherjeel Adnan,
  • Zeeshan Masood,
  • Muhammad Waqas,
  • Wafa Ishaq and
  • Nabeela Ameer

Beilstein J. Nanotechnol. 2025, 16, 652–663, doi:10.3762/bjnano.16.50

Graphical Abstract
  • , Robert Stevenson Road, Edinburgh, EH9 3FB, United Kingdom 10.3762/bjnano.16.50 Abstract Objectives of the present study are the development of aprepitant (APT)-loaded solid lipid nanoparticles (SLNs) using the polymers poloxamer 407 and β-cyclodextrin for enhanced solubility and their pharmacokinetic
  • . Therefore, the optimal SLN formulation APT-CD-NP4 is a promising tool for oral administration with sustained release to improve the bioavailability of the BCS class-IV drug APT. Keywords: aprepitant; β-cyclodextrin; pharmacokinetic study; poloxamer; solid lipid nanoparticles; Introduction Cancer is a
  • class-IV drug [10]. Low solubility and poor dissolution of BCS class-IV drugs can be improved by using techniques such as incorporating the drug or prodrug into lipid or polymeric formulations, using solid lipid nanoparticles (SLNs), applying surfactants, adjusting the pH value, reducing particle size
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Published 15 May 2025

Polyurethane/silk fibroin-based electrospun membranes for wound healing and skin substitute applications

  • Iqra Zainab,
  • Zohra Naseem,
  • Syeda Rubab Batool,
  • Muhammad Waqas,
  • Ahsan Nazir and
  • Muhammad Anwaar Nazeer

Beilstein J. Nanotechnol. 2025, 16, 591–612, doi:10.3762/bjnano.16.46

Graphical Abstract
  • biodegradable PU has been utilized to develop 3D printing materials with regulated bioactivity for cartilage tissue engineering [148]. The printing ink contains a water-based dispersion of synthetic biodegradable PU nanoparticles, hyaluronan, and bioactive substances. The ink was used at low temperatures to
  • neuronal development and embryonic stem cell culturing [161]. For biological applications, electrospun PU nanofibers including antibacterial substances such as silver nanoparticles, 4-vinylpyridine, or streptomycin sulfate were also created. These researches combined the use of wound dressings with the
  • therapeutic treatment [167]. These materials are embedded with responsive elements like nanoparticles that capture light in the near-infrared (NIR) or visible range and transform it to energy or heat to elicit specific responses. Such materials can, upon light exposure, release therapeutic payloads in the
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Published 24 Apr 2025

Nanomaterials in targeting amyloid-β oligomers: current advances and future directions for Alzheimer's disease diagnosis and therapy

  • Shiwani Randhawa,
  • Trilok Chand Saini,
  • Manik Bathla,
  • Rahul Bhardwaj,
  • Rubina Dhiman and
  • Amitabha Acharya

Beilstein J. Nanotechnol. 2025, 16, 561–580, doi:10.3762/bjnano.16.44

Graphical Abstract
  • to intermediates of the oligomerization process. Evidence from in vivo studies indicate that NMs hold promise for ameliorating AD symptoms. Additionally, the review explores the different interaction mechanisms through which nanoparticles exhibit their inhibitory effects on AβOs, providing insights
  • biosensors for early diagnosis and improving the sensitivity of AβO detection. In imaging, nanoparticles (NPs) can help to visualize localized protein accumulation, complementing existing diagnostic methods. Materials such as carbon-based NMs (e.g., graphene oxide) and metal NPs (e.g., gold and silver
  • electrochemical detection of AβOs via a nanobiosensor consisting of gold nanoparticles (AuNPs) embedded in a conductive polymeric matrix. For this, the surface of the AuNPs was further modified with PrPc, which acted as the biorecognition element for the specific detection of AβOs in ex vivo real samples, viz
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Published 22 Apr 2025

Retrieval of B1 phase from high-pressure B2 phase for CdO nanoparticles by electronic excitations in CdxZn1−xO composite thin films

  • Arkaprava Das,
  • Marcin Zając and
  • Carla Bittencourt

Beilstein J. Nanotechnol. 2025, 16, 551–560, doi:10.3762/bjnano.16.43

Graphical Abstract
  • Abstract This study investigates the recovery of the B1 phase from the high-pressure B2 phase, at atmospheric pressure, in cadmium oxide (CdO) nanoparticles incorporated within sol–gel synthesized CdxZn1−xO (x = 0.40) composite thin films. The recovery process is investigated using electronic excitations
  • as an effective tool. Exposure to 120 MeV silver ion irradiation results in the complete amorphization of the B2 phase in CdO nanoparticles, while the crystalline hexagonal wurtzite phase of zinc oxide (ZnO) remains intact. In contrast, 80 MeV oxygen ion irradiation preserves the B2 phase and
  • facilitates the reemergence of the B1 phase. The partial damage caused by electronic energy loss during oxygen ion irradiation in the willemite Zn2SiO4 phase is identified as a trigger for the B1 to B2 phase transformation in CdO nanoparticles, enabling the recovery of the B1 phase. The diminishing local
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Published 17 Apr 2025

Functionalized gold nanoflowers on carbon screen-printed electrodes: an electrochemical platform for biosensing hemagglutinin protein of influenza A H1N1 virus

  • Carlos Enrique Torres-Méndez,
  • Sharmilee Nandi,
  • Klara Martinovic,
  • Patrizia Kühne,
  • Yifan Liu,
  • Sam Taylor,
  • Maria Lysandrou,
  • Maria Ines Berrojo Romeyro Mascarenhas,
  • Viktoria Langwallner,
  • Javier Enrique Sebastián Alonso,
  • Ivana Jovanovic,
  • Maike Lüftner,
  • Georgia-Vasiliki Gkountana,
  • David Bern,
  • Abdul-Raouf Atif,
  • Ehsan Manouchehri Doulabi,
  • Gemma Mestres and
  • Masood Kamali-Moghaddam

Beilstein J. Nanotechnol. 2025, 16, 540–550, doi:10.3762/bjnano.16.42

Graphical Abstract
  • transducer system of our biosensor is based on low-cost carbon screen printed electrodes (CSPEs) modified with functionalized gold nanoflowers (AuNFs). The complex morphology and surface functionalization of the nanoparticles with 4-aminothiophenol (4-ATP) significantly increased the surface area and the
  • protein at clinically relevant concentrations. Scanning electron microscopy Scanning electron microscopy (SEM) analysis was explored to characterize the surface of the electrodes after electrodeposition of gold nanoparticles (Figure 2). Because of the high conductivity of gold, a difference in contrast is
  • observed when comparing the surface of the commercial CSPE (Figure 2A) to that of the AuNFs/CSPE (Figure 2B). The gold nanoparticles are evenly distributed across the surface of the electrode (Figure 2C). The deposited nanoparticles show a flower-like morphology with an average size of 139 nm and a
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Published 16 Apr 2025

Electron beam-based direct writing of nanostructures using a palladium β-ketoesterate complex

  • Chinmai Sai Jureddy,
  • Krzysztof Maćkosz,
  • Aleksandra Butrymowicz-Kubiak,
  • Iwona B. Szymańska,
  • Patrik Hoffmann and
  • Ivo Utke

Beilstein J. Nanotechnol. 2025, 16, 530–539, doi:10.3762/bjnano.16.41

Graphical Abstract
  • applications [32][33][34], palladium is an important metal as it is the optimal material to make metallic contacts with CNTs [35]. Palladium nanoparticles are also being explored for biomedical applications and sensors [36]. Therefore, Pd nanoprinting via FEBID could emerge as a key technique for creating
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Published 15 Apr 2025

N2+-implantation-induced tailoring of structural, morphological, optical, and electrical characteristics of sputtered molybdenum thin films

  • Usha Rani,
  • Kafi Devi,
  • Divya Gupta and
  • Sanjeev Aggarwal

Beilstein J. Nanotechnol. 2025, 16, 495–509, doi:10.3762/bjnano.16.38

Graphical Abstract
  • production of Mo nanoparticles and the subsequent increase in surface plasmon resonance or interband transitions. As-deposited molybdenum thin films deposited at room temperature typically exhibit a smooth surface and crystalline structure. The absorbance of molybdenum thin films increases with increasing
  • film thickness and peaks between 300 and 700 nm, corresponding to the localized surface plasmon resonance (LSPR) of molybdenum nanoparticles [45][46]. The formation of defects through ion irradiation increased the scattering of light and absorption within the film, resulting in enhanced overall
  • absorbance of Mo thin films. The blue shift of the LSPR band to a shorter wavelength (i.e., 260–340 nm) after nitrogen ion implantation can be attributed to modifications in the size, shape, and density of molybdenum nanoparticles [47]. The absorbance bands are more pronounced after nitrogen implantation
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Published 01 Apr 2025

Effect of additives on the synthesis efficiency of nanoparticles by laser-induced reduction

  • Rikuto Kuroda,
  • Takahiro Nakamura,
  • Hideki Ina and
  • Shuhei Shibata

Beilstein J. Nanotechnol. 2025, 16, 464–472, doi:10.3762/bjnano.16.35

Graphical Abstract
  • Rikuto Kuroda Takahiro Nakamura Hideki Ina Shuhei Shibata illuminus Inc., 307 Wako Riken Incubation Plaza, 2–3–13, Minami, Wako, Saitama, 351–0104, Japan 10.3762/bjnano.16.35 Abstract Laser-induced reduction in liquid (LRL) is a physicochemical technique for synthesizing nanoparticles by
  • irradiating a solution containing metal ions with a high-intensity laser. It is simple and environmentally friendly, as it does not require reducing agents or high-temperature, high-pressure environments. In this method, nanoparticles are synthesized by reducing metal ions with short-lived radical species
  • produced by the breakdown of solvent molecules in a high-intensity reaction field near the focus of the laser. This unique reaction has the characteristic of being able to synthesize non-equilibrium solid–solution alloy nanoparticles. On the other hand, it is necessary to improve the synthesis efficiency
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Published 27 Mar 2025

Synthetic-polymer-assisted antisense oligonucleotide delivery: targeted approaches for precision disease treatment

  • Ana Cubillo Alvarez,
  • Dylan Maguire and
  • Ruairí P. Brannigan

Beilstein J. Nanotechnol. 2025, 16, 435–463, doi:10.3762/bjnano.16.34

Graphical Abstract
  • optimise ASO-based therapeutics for more precise and effective disease treatments. Keywords: antisense oligonucleotides; enhanced delivery; gene transfection; intracellular uptake; locked nucleic acid (LNA); nanoparticles; peptide nucleic acid (PNA); personalised therapy; phosphorodiamidate morpholino
  • ) (εPLL) (≈4.2 kDa) as a cationic polymer to enhance the delivery of single-strand phosphorothioate backbone ASOs (ASO-GAPDH, ASO-PHD2, and ASO-Luci) through the formation of green nanoparticles (GNPs) with natural polyphenols such as epigallocatechin gallate [65]. The authors demonstrated that εPLL
  • played a crucial role in the successful coating of these nanoparticles, significantly increasing their zeta potential and improving cellular uptake. Moreover, εPLL-coated GNPs were found to provide robust protection for the ASOs against nuclease degradation, maintaining over 78% of the oligonucleotides
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Published 27 Mar 2025

Quantification of lead through rod-shaped silver-doped zinc oxide nanoparticles using an electrochemical approach

  • Ravinder Lamba,
  • Gaurav Bhanjana,
  • Neeraj Dilbaghi,
  • Vivek Gupta and
  • Sandeep Kumar

Beilstein J. Nanotechnol. 2025, 16, 422–434, doi:10.3762/bjnano.16.33

Graphical Abstract
  • , India Department of Physics, Punjab Engineering College (Deemed to be University), Chandigarh, 160012, India 10.3762/bjnano.16.33 Abstract Special features of zinc oxide nanoparticles have drawn a lot of interest due to their wide bandgap, high surface area, photocatalytic activity, antimicrobial
  • activity, and semiconductor properties. By doping ZnO nanoparticles with transition metals, we can alter their electrical, optical, and magnetic properties by introducing new electronic states into the band structure. Herein, Ag is added to ZnO nanostructures to improve their optical properties to detect
  • sensitivity toward lead. The lead chemical sensor that was developed had a detection limit of 3 ppm with a sensitivity of 16 µA·ppm−1·cm−2. The recorded reaction time of lead sensor was less than two seconds. Keywords: electrochemical methods; chemical sensor; doping; lead; nanoparticles; ZnO nanorods
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Published 26 Mar 2025

Size control of nanoparticles synthesized by pulsed laser ablation in liquids using donut-shaped beams

  • Abdel Rahman Altakroury,
  • Oleksandr Gatsa,
  • Farbod Riahi,
  • Zongwen Fu,
  • Miroslava Flimelová,
  • Andrei Samokhvalov,
  • Stephan Barcikowski,
  • Carlos Doñate-Buendía,
  • Alexander V. Bulgakov and
  • Bilal Gökce

Beilstein J. Nanotechnol. 2025, 16, 407–417, doi:10.3762/bjnano.16.31

Graphical Abstract
  • GROC·UJI, Institute of New Imaging Technologies, Universitat Jaume I, Av. de Vicent Sos Baynat, s/n, 12071 Castellón, Spain 10.3762/bjnano.16.31 Abstract The potential to modify the size distribution of nanoparticles synthesized by pulsed laser ablation in liquids is demonstrated using a donut-shaped
  • this pioneering study, further investigation with higher temporal and spatial resolution are warranted. Keywords: beam shaping; cavitation bubble; donut beam; gold nanoparticles; high-entropy alloy nanoparticles; nanoparticle size analysis; yttrium oxide nanoparticles; Introduction The demand for
  • nanoparticles (NPs) with defined particle sizes and narrow size distribution width is driven by the growing integration of nanomaterials into various industrial applications, such as medicine [1][2][3], catalysis [4][5], sensors [6][7], and additive manufacturing [8]. The performance of NPs typically depends on
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Published 25 Mar 2025

ReactorAFM/STM – dynamic reactions on surfaces at elevated temperature and atmospheric pressure

  • Tycho Roorda,
  • Hamed Achour,
  • Matthijs A. van Spronsen,
  • Marta E. Cañas-Ventura,
  • Sander B. Roobol,
  • Willem Onderwaater,
  • Mirthe Bergman,
  • Peter van der Tuijn,
  • Gertjan van Baarle,
  • Johan W. Bakker,
  • Joost W. M. Frenken and
  • Irene M. N. Groot

Beilstein J. Nanotechnol. 2025, 16, 397–406, doi:10.3762/bjnano.16.30

Graphical Abstract
  • show operando combined AFM/STM images of a clean Pd(100) single crystal that undergoes oxidation of the surface. The oxidation happens at 450 K under 0.5 bar of oxygen atmosphere. The second experiment is a FTS experiment, where we show AFM images of catalytic cobalt nanoparticles. The nanoparticles
  • hydrocarbons CnH2n+2, with water as byproduct [24]. We have investigated the reaction on Co nanoparticles deposited on an Al2O3 support, grown on a NiAl(110) single crystal. The NiAl(110) surface has been prepared by repeated cycles of Ar-ion sputtering (3 μA, 1 kV, 30 min) at room temperature followed by
  • the main setup, the sample is annealed at 800 K in 10−6 mbar of O2 to remove carbon impurities and replenish the oxygen in the oxide layer. The composition of the surface was verified by AES (not shown here). The cobalt nanoparticles were deposited by e-beam evaporation with a Co rod, an emission
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Published 21 Mar 2025

Engineered PEG–PCL nanoparticles enable sensitive and selective detection of sodium dodecyl sulfate: a qualitative and quantitative analysis

  • Soni Prajapati and
  • Ranjana Singh

Beilstein J. Nanotechnol. 2025, 16, 385–396, doi:10.3762/bjnano.16.29

Graphical Abstract
  • , labor-intensive, and require specialized technical expertise. This study developed a novel colorimetric method for the selective and sensitive detection of SDS, utilizing polyethylene glycol-polycaprolactone nanoparticles (PEG–PCL NPs) synthesized via a ring-opening polymerization approach. The
  • synthesized nanoparticles exhibited a distinct colorimetric response to SDS when combined with the Bradford reagent, which acted as a linker molecule. Interference studies demonstrated the high selectivity of the method, even in the presence of various heavy metals and other surfactants. The method showed
  • selectivity and sensitivity for SDS detection, making it a promising analytical tool for rapid and onsite estimation. Keywords: Bradford reagent; environmental monitoring; PEG–PCL nanoparticles; SDS; SDS detection; Introduction Sodium dodecyl sulfate (SDS), or sodium lauryl sulfate, is an anionic surfactant
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Published 20 Mar 2025

Development of a mucoadhesive drug delivery system and its interaction with gastric cells

  • Ahmet Baki Sahin,
  • Serdar Karakurt and
  • Deniz Sezlev Bilecen

Beilstein J. Nanotechnol. 2025, 16, 371–384, doi:10.3762/bjnano.16.28

Graphical Abstract
  • mucoadhesive drug delivery system that was developed to fulfill these requirements. Alginate nanoparticles were synthesized by water-in-oil emulsification followed by external gelation and then coated with the mucoadhesive polymer Eudragit RS100. The formulated nanoparticles had a mean size of 219 nm and
  • positive charge. A peptide, as a model drug, was loaded onto the nanoparticles with an encapsulation efficiency of 58%. The release of the model drug from the delivery system was pH-independent and lasted for 7 days. The periodic acid–Schiff stain assay indicated 69% mucin interaction for the nanoparticles
  • , which were also capable of diffusion through artificial mucus. The nanoparticles were not toxic to gastric epithelial cells and can be internalized by the cells within 4 h. The adsorption of nanoparticles onto mucus-secreting gastric cells was found to be correlated with cell number. The delivery system
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Published 13 Mar 2025

Pulsed laser in liquid grafting of gold nanoparticle–carbon support composites

  • Madeleine K. Wilsey,
  • Teona Taseska,
  • Qishen Lyu,
  • Connor P. Cox and
  • Astrid M. Müller

Beilstein J. Nanotechnol. 2025, 16, 349–361, doi:10.3762/bjnano.16.26

Graphical Abstract
  • , University of Rochester, Rochester, New York 14627, United States 10.3762/bjnano.16.26 Abstract We developed a novel pulsed laser-assisted process for the fabrication of advanced composites of nonequilibrium gold nanoparticles on carbon fiber paper supports. Our one-step process integrates the generation of
  • nanoparticles with their surface attachment and solves longstanding nanoparticle adhesion and electrical contact issues. Irradiation of hydrophilic carbon fiber paper submerged in aqueous HAuCl4 solution by nanosecond laser pulses produced composites with uniform distribution of gold nanoparticles on carbon
  • fibers, taking advantage of the high internal surface area of carbon fiber paper. The pulsed laser-grafted composites exhibited zero measurable charge transfer resistance between gold nanoparticles and the carbon support, leading to superior cathode performance over conventionally prepared electrodes for
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Published 07 Mar 2025

Graphene oxide–chloroquine conjugate induces DNA damage in A549 lung cancer cells through autophagy modulation

  • Braham Dutt Arya,
  • Sandeep Mittal,
  • Prachi Joshi,
  • Alok Kumar Pandey,
  • Jaime E. Ramirez-Vick,
  • Govind Gupta and
  • Surinder P. Singh

Beilstein J. Nanotechnol. 2025, 16, 316–332, doi:10.3762/bjnano.16.24

Graphical Abstract
  • exposure to starch-capped silver nanoparticles (AgNPs) [11]. Gemcitabine-encapsulated poly(lactic-co-glycolic acid) (PLGA) nanoparticles have been shown to enhance cell death in chemoresistant PANC1 cells, human pancreatic epithelial carcinoma cells [12]. Also, TiO2 nanoparticles can sensitize A549 cells
  • , human lung epithelial carcinoma cells towards the genotoxic agent methyl methanesulphonate through disruption of the DDR process [13]. Recently, ZnO nanoparticles induced significant cytotoxicity and DNA double-strand breaks in SKOV3 cells, human ovarian epithelial cancer cells, through induction of
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Published 03 Mar 2025

Fabrication and evaluation of BerNPs regarding the growth and development of Streptococcus mutans

  • Tuyen Huu Nguyen,
  • Hong Thanh Pham,
  • Kieu Kim Thanh Nguyen,
  • Loan Hong Ngo,
  • Anh Ngoc Tuan Mai,
  • Thu Hoang Anh Lam,
  • Ngan Thi Kim Phan,
  • Dung Tien Pham,
  • Duong Thuy Hoang,
  • Thuc Dong Nguyen and
  • Lien Thi Xuan Truong

Beilstein J. Nanotechnol. 2025, 16, 308–315, doi:10.3762/bjnano.16.23

Graphical Abstract
  • Faculty of Medical Technology, Van Lang University, Ho Chi Minh City, Vietnam Department of Biotechnology, Nong Lam University, Ho Chi Minh City, Vietnam Faculty of Pharmacy, Van Lang University, Ho Chi Minh City, Vietnam 10.3762/bjnano.16.23 Abstract In this study, berberine nanoparticles (BerNPs) were
  • formation of S. mutans. In summary, BerNPs demonstrated a potent inhibitory effect on the activities of S. mutans at selectively applied concentrations. Keywords: antibacterial; berberine nanoparticles; BerNPs; biofilm; FE-SEM; Streptococcus mutans; Introduction According to the Global Burden of Disease
  • inhibitory activity against pathogenic bacteria have been reported. In 2022, Nguyen et al. fabricated berberine nanoparticles (BerNPs) by antisolvent precipitation (ASP) using glycerol as a safe organic solvent and evaluated their antibacterial activity on S. aureus and E. coli O157:H7 [12]. Additionally
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Published 27 Feb 2025

Enhancing mechanical properties of chitosan/PVA electrospun nanofibers: a comprehensive review

  • Nur Areisman Mohd Salleh,
  • Amalina Muhammad Afifi,
  • Fathiah Mohamed Zuki and
  • Hanna Sofia SalehHudin

Beilstein J. Nanotechnol. 2025, 16, 286–307, doi:10.3762/bjnano.16.22

Graphical Abstract
  • also be used to incorporate nanoparticles into the nanofiber structures through simultaneous electrospinning and electrospraying [88]. In co-electrospinning, the interaction between charged jets for nozzles that are positioned close to one another may cause jet repulsion for nozzles of the same
  • nanocomposites have been produced through the substantial utilization of nanoparticles. The development of fibrous nanocomposites or bio-nanocomposites, where the matrix and/or fillers are biomaterials, has been advanced in recent years by introducing nanoscale materials into electrospun fibers in the form of
  • compared to electrospun fibers without nanoclay. This improvement is due to the dispersion of nanoparticles within the polymer matrices, which plays an important role in enhancing the physical and mechanical properties of electrospun nanofiber [169]. The purpose of surface modification is to increase the
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Published 26 Feb 2025
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