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Search for "phase" in Full Text gives 1486 result(s) in Beilstein Journal of Nanotechnology. Showing first 200.

Vortex lattices of layered HTSCs at different vortex–vortex interaction potentials

  • Valerii P. Lenkov,
  • Anastasia N. Maksimova,
  • Anna N. Moroz and
  • Vladimir A. Kashurnikov

Beilstein J. Nanotechnol. 2025, 16, 362–370, doi:10.3762/bjnano.16.27

Graphical Abstract
  • ; Introduction Type-II superconductors, as shown by numerous studies, have a complex phase diagram in a magnetic field. In fields greater than the first critical field Hc1 and less than the second critical field Hc2, at temperatures below the critical temperature the superconductor is in a mixed state, in which
  • ordering of the pancakes, which also enhances the pinning of vortices on defects. In [8], the vortex system in a HgBa2CuO4+δ monocrystal was studied. The measurements were performed in a wide range of temperatures and magnetic fields, and the phase diagram of the vortex system was obtained as a result of
  • with respect to the superconducting planes. The phase diagram of the vortex system becomes even more complex in an inclined magnetic field. As studies [9][10][11] have shown, the structure of the vortex lattice depends on the anisotropy parameter of the superconductor in the form of the Josephson
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Published 13 Mar 2025

Pulsed laser in liquid grafting of gold nanoparticle–carbon support composites

  • Madeleine K. Wilsey,
  • Teona Taseska,
  • Qishen Lyu,
  • Connor P. Cox and
  • Astrid M. Müller

Beilstein J. Nanotechnol. 2025, 16, 349–361, doi:10.3762/bjnano.16.26

Graphical Abstract
  • trapped materials that are not accessible under thermodynamic equilibrium conditions [1]. Pulsed laser grafting permits access to extreme regions of materials phase diagrams by concentrating the laser energy into the region where nanoparticles emerge, followed by rapid cooling. Kinetically trapped
  • , evident from electrochemical impedance spectroscopy (EIS) data (Figure 5B). Impedance, measured in an electrochemical setup, is the time-dependent opposition to alternating current stemming from the combined effect of ohmic resistance, capacitance, and phase elements in an electronic circuit. Impedance is
  • redox species to the electrode, and the ubiquitous capacitance at the interface between the electrode and the electrolyte. This capacitance is non-ideal at the porous, non-flat gold nanoparticle–carbon fiber paper electrode, necessitating incorporation of a constant phase element. In a Nyquist plot
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Published 07 Mar 2025

Tailoring of physical properties of RF-sputtered ZnTe films: role of substrate temperature

  • Kafi Devi,
  • Usha Rani,
  • Arun Kumar,
  • Divya Gupta and
  • Sanjeev Aggarwal

Beilstein J. Nanotechnol. 2025, 16, 333–348, doi:10.3762/bjnano.16.25

Graphical Abstract
  • . Comparison with the JCPDS card no. 00-019-1482 reveals that these correspond, respectively, to the (102) and (202) reflections of the hexagonal ZnTe phase. Thus, a mixture of phases exists at this substrate temperature. Other very low-intensity peaks at this temperature are from pure Zn and Te. The
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Published 05 Mar 2025

Graphene oxide–chloroquine conjugate induces DNA damage in A549 lung cancer cells through autophagy modulation

  • Braham Dutt Arya,
  • Sandeep Mittal,
  • Prachi Joshi,
  • Alok Kumar Pandey,
  • Jaime E. Ramirez-Vick,
  • Govind Gupta and
  • Surinder P. Singh

Beilstein J. Nanotechnol. 2025, 16, 316–332, doi:10.3762/bjnano.16.24

Graphical Abstract
  • permeability to chemotherapeutics, which leads to alterations in the cell cycle, genotoxicity, and autophagy modulation in cancer cells [39][55]. The cell cycle includes a division phase and an interphase which are responsible for the efficient cellular physiology and metabolic pathways. Any impairment in the
  • . Figure 6 reveals the cell cycle analysis of A549 cells exposed to GO–Chl. Results showed a significant increase in the population of cells in the sub G1 phase (reduced DNA content), which could be attributed to possible DNA fragmentation and ultimate A549 cell death by the exposure to the GO–Chl
  • nanoconjugate. However, as observed in Figure 6E and Figure 6F, the P2 population was slightly moved towards the P5 which could be attributed to either the arrest of cells in the subG0/G1 phase before their migration or could be related to alterations in the marker intensity due to the treatments. Genotoxicity
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Published 03 Mar 2025

Enhancing mechanical properties of chitosan/PVA electrospun nanofibers: a comprehensive review

  • Nur Areisman Mohd Salleh,
  • Amalina Muhammad Afifi,
  • Fathiah Mohamed Zuki and
  • Hanna Sofia SalehHudin

Beilstein J. Nanotechnol. 2025, 16, 286–307, doi:10.3762/bjnano.16.22

Graphical Abstract
  • , phase separation, self-assembly, and electrospinning. Electrospinning is considered the most versatile and widely used technique for nanofiber fabrication, offering greater control over fiber structures, higher productivity, simplicity, lower cost, and potential for industrial use [69][70
  • single-phase homogeneous liquid. Polymer blending allows for the creation of novel materials through the incorporation of the unique properties of the component polymers [78]. In blend electrospinning, the preparation of a homogenous solution is crucial in ensuring the formation of uniform fibers during
  • steps but minimizes the risk of incomplete dissolution or phase separation due to different solubility requirements of each polymer [84]. Nevertheless, the instabilities can still occur when blending the two solutions if the solvents are incompatible. Sequential electrospinning Sequential
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Published 26 Feb 2025

Emerging strategies in the sustainable removal of antibiotics using semiconductor-based photocatalysts

  • Yunus Ahmed,
  • Keya Rani Dutta,
  • Parul Akhtar,
  • Md. Arif Hossen,
  • Md. Jahangir Alam,
  • Obaid A. Alharbi,
  • Hamad AlMohamadi and
  • Abdul Wahab Mohammad

Beilstein J. Nanotechnol. 2025, 16, 264–285, doi:10.3762/bjnano.16.21

Graphical Abstract
  • -Bi2O3 appearing at high temperatures. Scientists have noted that Bi2O3 in the metastable phase can undergo a transformation into (BiO)2CO3, which limits its potential as an effective visible photocatalyst because of its chemical instability [85]. Furthermore, β-Bi2O3 exhibits enhanced photocatalytic
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Published 25 Feb 2025

Preferential enrichment and extraction of laser-synthesized nanoparticles in organic phases

  • Theo Fromme,
  • Maximilian L. Spiekermann,
  • Florian Lehmann,
  • Stephan Barcikowski,
  • Thomas Seidensticker and
  • Sven Reichenberger

Beilstein J. Nanotechnol. 2025, 16, 254–263, doi:10.3762/bjnano.16.20

Graphical Abstract
  • ) functionalization of the nanoparticles have been observed, which ultimately should affect their lipophilicity and, hence, colloidal stability in apolar or polar solvents. Two-phase liquid systems and the possibility to transfer the surfactant-free nanoparticles from one liquid phase into another remain practically
  • unaddressed in literature. To tackle this knowledge gap, the present study investigates the phase preference of laser-generated noble metal (Au and Ag) and base metal (Cu, Fe, Al and Ti) nanoparticles within propylene carbonate/alcohol (PC/A) systems. Alcohols of increasing chain length (C6–C11) and hence
  • decreasing polarity were chosen for this study. For each metal, LAL was performed at elevated temperatures (85 °C) where the PC/A mixture forms a single phase. Upon cooling, the phases separated and the amount of colloidal nanoparticles in the alcohol and propylene carbonate phase was analyzed for each metal
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Published 20 Feb 2025

Radiosensitizing properties of dual-functionalized carbon nanostructures loaded with temozolomide

  • Radmila Milenkovska,
  • Nikola Geskovski,
  • Dushko Shalabalija,
  • Ljubica Mihailova,
  • Petre Makreski,
  • Dushko Lukarski,
  • Igor Stojkovski,
  • Maja Simonoska Crcarevska and
  • Kristina Mladenovska

Beilstein J. Nanotechnol. 2025, 16, 229–251, doi:10.3762/bjnano.16.18

Graphical Abstract
  • irradiated and non-irradiated CNs. In vitro release All functionalized CNs loaded with TMZ manifested a biphasic release profile, with an initial burst release and a phase of continuous release (observed also in non-covalently PEGylated formulations in our previous study [43]). In the initial phase of 2 h
  • effects on the proliferation of cancer cells by blocking the cell cycle in the G0/G1 phase and increasing the osmotic pressure [91][92]. In addition, in a paper of Xu et al. [93], dynamic biological interactions between PEG and cells on the molecular level were clarified, explaining both the inhibitory
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Published 19 Feb 2025

Recent advances in photothermal nanomaterials for ophthalmic applications

  • Jiayuan Zhuang,
  • Linhui Jia,
  • Chenghao Li,
  • Rui Yang,
  • Jiapeng Wang,
  • Wen-an Wang,
  • Heng Zhou and
  • Xiangxia Luo

Beilstein J. Nanotechnol. 2025, 16, 195–215, doi:10.3762/bjnano.16.16

Graphical Abstract
  • demonstrated therapeutic effects that excel traditional thermal therapies. The studies reviewed herein underscore the promising clinical potential of photothermal nanomaterials in ophthalmology (Table 1). Presently, research in this field remains predominantly in the conceptual validation phase, but it holds
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Published 17 Feb 2025

A review of metal-organic frameworks and polymers in mixed matrix membranes for CO2 capture

  • Charlotte Skjold Qvist Christensen,
  • Nicholas Hansen,
  • Mahboubeh Motadayen,
  • Nina Lock,
  • Martin Lahn Henriksen and
  • Jonathan Quinson

Beilstein J. Nanotechnol. 2025, 16, 155–186, doi:10.3762/bjnano.16.14

Graphical Abstract
  • a thin layer atop a polymer support. Solvent removal following casting yields the finalized MOF-based MMM. This casting method is simple and cost-effective but is primarily relevant in small-scale applications. Asymmetric membranes can alternatively be prepared via phase inversion, where the
  • precursor slurry undergoes phase separation under altered solvent, composition, or temperature conditions to form a porous support phase and a dense MMM phase [80][87][92][94]. Finally, fabrication of thin selective MMM layers on top of porous substrates can be accomplished via spin coating [95]. Defects
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Published 12 Feb 2025

Clays enhanced with niobium: potential in wastewater treatment and reuse as pigment with antibacterial activity

  • Silvia Jaerger,
  • Patricia Appelt,
  • Mario Antônio Alves da Cunha,
  • Fabián Ccahuana Ayma,
  • Ricardo Schneider,
  • Carla Bittencourt and
  • Fauze Jacó Anaissi

Beilstein J. Nanotechnol. 2025, 16, 141–154, doi:10.3762/bjnano.16.13

Graphical Abstract
  • natural clay has predominantly the bentonite phase (at least 50%), known as montmorillonite. Isomorphic substitution of cations between the interlayer space of montmorillonites by exchanging Na+, Ca2+, Mg2+, and Cu2+ cations add other functionalities to the resulting material [7]. Heterogeneous
  • reflections of montmorillonite (M) for the basal spacing correspond to approximately 15 Å (d001 = 14.88 Å), related to the interlayer distance of 2:1 clays, resulting in a spacing between 14.0–15.0 Å corresponding to the peak at 6.17 2θ (o) [11]. The quartz phase (Q) was identified by the presence of
  • reflections at 2θ = 50.02° and 68.32°. The characteristic peaks that allowed the identification of the kaolinite phase (K) were at 2θ = 12.48°and 20.14° [7]. Figure 2a,b presents diffraction patterns with amorphous characteristics of the niobium compounds NbOPO4 and Nb2O5. Two broad peaks were identified, one
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Published 10 Feb 2025

TiO2 immobilized on 2D mordenite: effect of hydrolysis conditions on structural, textural, and optical characteristics of the nanocomposites

  • Marina G. Shelyapina,
  • Rosario Isidro Yocupicio-Gaxiola,
  • Gleb A. Valkovsky and
  • Vitalii Petranovskii

Beilstein J. Nanotechnol. 2025, 16, 128–140, doi:10.3762/bjnano.16.12

Graphical Abstract
  • hybrid zeolite–CTAB aggregates, inorganic pillars are pre-formed in the CTAB layers, which will keep the zeolite lamellae from collapsing when burning the organic phase. The flexibility in the choice of material to form pillars creates a wide range of potential new materials for targeted applications
  • similarly leads to the formation of TiO2. TiO2 is a well-known photocatalyst whose efficiency depends on a number of factors, including the crystalline phase, particle size, and degree of crystallinity. The most active phase of TiO2 is considered to be anatase. Its nanoparticles usually show higher
  • efficiency than the bulk phase, but the bandgap of anatase particles smaller than 10 nm is very sensitive to their size [14]. One of the disadvantages of such free photocatalyst nanoparticles is the limitation of mass transfer between solid and liquid phases. From this perspective, the problem of
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Published 10 Feb 2025

Modeling and simulation of carbon-nanocomposite-based gas sensors

  • Roopa Hegde,
  • Punya Prabha V,
  • Shipra Upadhyay and
  • Krishna S B

Beilstein J. Nanotechnol. 2025, 16, 90–96, doi:10.3762/bjnano.16.9

Graphical Abstract
  • model was initially formulated to characterize gas adsorption on solid-phase adsorbents such as carbon-based adsorbents [13]. The fundamental assumptions of the Langmuir isotherm include: (1) adsorption occurs as a monolayer; (2) adsorption sites are uniformly distributed; (3) the adsorption energy
  • settings for time-dependent and stationary analyses. In the solving phase, simulations are executed to generate results, followed by post-processing to analyse and present the outcomes in 1D and 3D plots. The sensor layer where the adsorption of the gas occurs and thus participate in detecting the CO gas
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Published 30 Jan 2025

Characterization of ZnO nanoparticles synthesized using probiotic Lactiplantibacillus plantarum GP258

  • Prashantkumar Siddappa Chakra,
  • Aishwarya Banakar,
  • Shriram Narayan Puranik,
  • Vishwas Kaveeshwar,
  • C. R. Ravikumar and
  • Devaraja Gayathri

Beilstein J. Nanotechnol. 2025, 16, 78–89, doi:10.3762/bjnano.16.8

Graphical Abstract
  • peak current, though a steady addition led to decreased currents, possibly due to surface accumulation. The Nyquist plots display a larger impedance for ZnO electrodes. To fit the data into an analogous circuit, an uninterrupted phase element (Q1) was introduced with the adjustable parameters angular
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Published 30 Jan 2025

Instance maps as an organising concept for complex experimental workflows as demonstrated for (nano)material safety research

  • Benjamin Punz,
  • Maja Brajnik,
  • Joh Dokler,
  • Jaleesia D. Amos,
  • Litty Johnson,
  • Katie Reilly,
  • Anastasios G. Papadiamantis,
  • Amaia Green Etxabe,
  • Lee Walker,
  • Diego S. T. Martinez,
  • Steffi Friedrichs,
  • Klaus M. Weltring,
  • Nazende Günday-Türeli,
  • Claus Svendsen,
  • Christine Ogilvie Hendren,
  • Mark R. Wiesner,
  • Martin Himly,
  • Iseult Lynch and
  • Thomas E. Exner

Beilstein J. Nanotechnol. 2025, 16, 57–77, doi:10.3762/bjnano.16.7

Graphical Abstract
  • draft of the experimental workflow at the study design phase and then associating this workflow with the materials, environmental conditions, method descriptions, protocols, biological and computational models used, and the data produced during the study. Indeed, this use of instance maps to inform the
  • , creation dates, licences, contributors, and references for the complete map as well as for individual nodes, as well as links (URLs or relative paths) to data files. This approach was chosen in the test phase to allow users greater flexibility with respect to the format in which their data is stored
  • polyvinylpyrrolidone (PVP) surface by reduction of silver nitrate in ethylene glycol with 10k PVP. The PVP-AgNPs are characterised regarding some of their physical attributes such as the particles’ shape, size, and crystalline phase. The particles are then sulfidised using different specified concentrations of the PVP
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Published 22 Jan 2025

Precursor sticking coefficient determination from indented deposits fabricated by electron beam induced deposition

  • Alexander Kuprava and
  • Michael Huth

Beilstein J. Nanotechnol. 2025, 16, 35–43, doi:10.3762/bjnano.16.4

Graphical Abstract
  • attributed to a larger precursor supply from the gas phase. Although the use of the Pt-precursor did not result in a volcano-shape deposit, an estimation of the sticking coefficient for it is nevertheless possible with precursor parameter values previously assessed. Unlike the Cr(C6H6)2 precursor, which has
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Published 13 Jan 2025

Bioinspired nanofilament coatings for scale reduction on steel

  • Siad Dahir Ali,
  • Mette Heidemann Rasmussen,
  • Jacopo Catalano,
  • Christian Husum Frederiksen and
  • Tobias Weidner

Beilstein J. Nanotechnol. 2025, 16, 25–34, doi:10.3762/bjnano.16.3

Graphical Abstract
  • maximum pressure of 200 bar. The liquid phase is pressurized via an inert gas (e.g., Ar or N2). (B) Top view of the static plate where three samples are mounted; around half of the surface area for each sample is exposed at constant sheer stress. (C) Steady state simulation of the velocity profile
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Published 09 Jan 2025

A nanocarrier containing carboxylic and histamine groups with dual action: acetylcholine hydrolysis and antidote atropine delivery

  • Elina E. Mansurova,
  • Andrey A. Maslennikov,
  • Anna P. Lyubina,
  • Alexandra D. Voloshina,
  • Irek R. Nizameev,
  • Marsil K. Kadirov,
  • Anzhela A. Mikhailova,
  • Polina V. Mikshina,
  • Albina Y. Ziganshina and
  • Igor S. Antipin

Beilstein J. Nanotechnol. 2025, 16, 11–24, doi:10.3762/bjnano.16.2

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  • molecules. Within a microemulsion system, they self-assemble at the interface between water and oil. The hydrophilic groups face the aqueous phase, while the resorcinarene scaffold with tails on the lower rim points towards the dispersed (oil) phase. Under slightly basic conditions (pH 8.5), resorcinarenes
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Published 09 Jan 2025

Fabrication of hafnium-based nanoparticles and nanostructures using picosecond laser ablation

  • Abhishek Das,
  • Mangababu Akkanaboina,
  • Jagannath Rathod,
  • R. Sai Prasad Goud,
  • Kanaka Ravi Kumar,
  • Raghu C. Reddy,
  • Ratheesh Ravendran,
  • Katia Vutova,
  • S. V. S. Nageswara Rao and
  • Venugopal Rao Soma

Beilstein J. Nanotechnol. 2024, 15, 1639–1653, doi:10.3762/bjnano.15.129

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  • University, Varanasi 221005, Uttar Pradesh, India Advanced Centre of Research in High Energy Materials (ACRHEM), DRDO Industry Academia – Centre of Excellence (DIA-COE), University of Hyderabad, Hyderabad 500046, Telangana, India Centre for Materials for Electronics Technology (C-MET), IDA Phase III
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Published 18 Dec 2024

Heterogeneous reactions in a HFCVD reactor: simulation using a 2D model

  • Xochitl Aleyda Morán Martínez,
  • José Alberto Luna López,
  • Zaira Jocelyn Hernández Simón,
  • Gabriel Omar Mendoza Conde,
  • José Álvaro David Hernández de Luz and
  • Godofredo García Salgado

Beilstein J. Nanotechnol. 2024, 15, 1627–1638, doi:10.3762/bjnano.15.128

Graphical Abstract
  • ]. Also, modeling of CVD microreactors at atmospheric pressure using tetraethyl orthosilicate as a source to obtain SiO2 has been achieved through computational fluid dynamics (CFD) simulations [22]. The gas-phase and surface reactions were analyzed using direct Monte Carlo simulations of a hot wire
  • parameters of the heterogeneous reaction between H° in the gas phase and quartz to describe its behavior as a function of temperature at constant pressure. The thermodynamic data obtained and those taken from the bibliography will be used in the Arrhenius equation to calculate the thermodynamic and transport
  • properties of the system in the gas phase in a dimensionless and temporal model. The thermodynamic and transport properties of the mixture will permit a study in the steady state considering the dimensions of the HFCVD reactor and the deposition parameters through numerically solving the equations of
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Published 17 Dec 2024

Liver-targeting iron oxide nanoparticles and their complexes with plant extracts for biocompatibility

  • Shushanik A. Kazaryan,
  • Seda A. Oganian,
  • Gayane S. Vardanyan,
  • Anatolie S. Sidorenko and
  • Ashkhen A. Hovhannisyan

Beilstein J. Nanotechnol. 2024, 15, 1593–1602, doi:10.3762/bjnano.15.125

Graphical Abstract
  • increase in total protein content. Increases compared to almost normal albumin levels are characteristic in pathological conditions when the total protein fraction increases due to acute phase proteins. Increases in total protein content may also be due to the release of ALT, AST, ALP, and GGT enzymes into
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Published 11 Dec 2024

The round-robin approach applied to nanoinformatics: consensus prediction of nanomaterials zeta potential

  • Dimitra-Danai Varsou,
  • Arkaprava Banerjee,
  • Joyita Roy,
  • Kunal Roy,
  • Giannis Savvas,
  • Haralambos Sarimveis,
  • Ewelina Wyrzykowska,
  • Mateusz Balicki,
  • Tomasz Puzyn,
  • Georgia Melagraki,
  • Iseult Lynch and
  • Antreas Afantitis

Beilstein J. Nanotechnol. 2024, 15, 1536–1553, doi:10.3762/bjnano.15.121

Graphical Abstract
  • , predictions of those two NMs are not considered reliable. AdaBoost regression model Data preprocessing The initial phase of feature selection involved categorizing descriptors into those with continuous numerical values (e.g., hydrodynamic diameter) and those with qualitative or “descriptive” details (e.g
  • continuous set and the binary set, were merged into a unified dataset that enabled us to explore relationships between different types of descriptors and their collective influence on the NMs ZP. During the initial modelling phase, the AdaBoost algorithm, integrated within the scikit-learn library, was
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Published 29 Nov 2024

Electrochemical nanostructured CuBTC/FeBTC MOF composite sensor for enrofloxacin detection

  • Thi Kim Ngan Nguyen,
  • Tien Dat Doan,
  • Huy Hieu Luu,
  • Hoang Anh Nguyen,
  • Thi Thu Ha Vu,
  • Quang Hai Tran,
  • Ha Tran Nguyen,
  • Thanh Binh Dang,
  • Thi Hai Yen Pham and
  • Mai Ha Hoang

Beilstein J. Nanotechnol. 2024, 15, 1522–1535, doi:10.3762/bjnano.15.120

Graphical Abstract
  • ), 20.36° (600), 21.40° (620), 23.55° (444), 24.27° (551), 26.11° (731), 29.47° (751), 35.30° (773), and 39.21° (882), characteristic for the CuBTC phase (CCDC card No. 112954) [28][33][34]. The XRD pattern of (Cu)(Fe)BTC exhibits a characteristic peak at 2θ of 10.85° assigned to the (842) crystal planes
  • of the Fe-BTC phase, and all characteristic peaks of CuBTC appear. It can be observed that the characteristic peaks of pure FeBTC have a much lower intensity than those of pure CuBTC; therefore, the intensity of the characteristic peaks of the CuBTC phase predominates in the (Cu)(Fe)BTC pattern. The
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Published 28 Nov 2024

Integrating high-performance computing, machine learning, data management workflows, and infrastructures for multiscale simulations and nanomaterials technologies

  • Fabio Le Piane,
  • Mario Vozza,
  • Matteo Baldoni and
  • Francesco Mercuri

Beilstein J. Nanotechnol. 2024, 15, 1498–1521, doi:10.3762/bjnano.15.119

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  • scales. Physics-based models provide insights into the fundamental mechanisms governing materials phenomena, such as structural changes, phase transitions, and mechanical responses. Empirical models, in contrast, are derived from experimental observations and statistical analyses. These models rely on
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Published 27 Nov 2024

Polymer lipid hybrid nanoparticles for phytochemical delivery: challenges, progress, and future prospects

  • Iqra Rahat,
  • Pooja Yadav,
  • Aditi Singhal,
  • Mohammad Fareed,
  • Jaganathan Raja Purushothaman,
  • Mohammed Aslam,
  • Raju Balaji,
  • Sonali Patil-Shinde and
  • Md. Rizwanullah

Beilstein J. Nanotechnol. 2024, 15, 1473–1497, doi:10.3762/bjnano.15.118

Graphical Abstract
  • absorption in the GIT, which significantly limits its bioavailability [87][88]. Moreover, QCT undergoes extensive phase-II metabolism in the liver and intestines, resulting in rapid clearance from the body and further reducing its systemic availability [89][90]. To surmount these issues, Das and co-workers
  • ][159]. Yu et al. fabricated BRN-PLHNPs for improved GI stability, intestinal permeation, and oral bioavailability [160]. The developed BRN-PLHNPs were stable in GI fluids and revealed a biphasic release pattern, characterized by an initial burst release of BRN during the early phase, followed by a
  • sustained release of BRN in the later phase, extending up to 24 h. The developed BRN-PLHNPs revealed significantly higher intestinal permeation and 3.4-fold increased bioavailability compared to the conventional BRN suspension. The improved intestinal permeation and oral bioavailability are attributed to (i
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Published 22 Nov 2024
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