Time of flight secondary ion mass spectrometry imaging of contaminant species in chemical vapour deposited graphene on copper

• Barry Brennan,
• Vlad-Petru Veigang-Radulescu,
• Philipp Braeuninger-Weimer,
• Stephan Hofmann and
• Andrew J. Pollard

Beilstein J. Nanotechnol. 2026, 17, 200–213, doi:10.3762/bjnano.17.13

• remove the top surface layer of the foil and reduce surface roughness (EP) or a wet back side oxidation process to introduce oxygen into the Cu foil prior to growth (BO). The electro-polishing solution was prepared by mixing H3PO4 (85 wt % in H2O, Sigma Aldrich) in a 7:3 ratio with DI water. The cathode

• (Cu foil) area was chosen to be four times larger than the anode. The distance between cathode and anode was 4 cm. After electro-polishing the Cu foil was rinsed in a water jet for 5 min and then dried with N2 after dipping in isopropyl alcohol (IPA). The oxidation of the Cu foil was performed in a 30

• % H2O2 solution (Fisher Scientific) heated to 100 °C for 300 s. The Cu foil was gently placed on the H2O2 solution such that the Cu foil floated, and the top side was not exposed to hydrogen peroxide. Subsequently, the Cu foil was rinsed in DI water and IPA and dried with flowing N2. The surface

Safe and sustainable by design with ML/AI: A transformative approach to advancing nanotechnology

• Georgia Melagraki

Beilstein J. Nanotechnol. 2026, 17, 176–185, doi:10.3762/bjnano.17.11

• , engineered nanomaterials (ENMs) have been employed for environmental applications, such as water purification and pollutant removal, addressing some of the most pressing ecological challenges [4][5]. Nanotechnology has significant applications in defence [6], particularly in the development of lightweight

• in air and water under high temperature and pressures and following release and uptake by biota [9]. Therefore, LCA must account for the entire lifecycle of these materials, from production and usage for which industrial materials can often be under extreme conditions (high temperatures, pressures

• detailed picture of how ENMs move through – and possibly accumulate in – soil, water, and air. By enabling stakeholders to test “what-if” scenarios, such as accidental spills or long-term usage in consumer products, digital twins enhance predictive accuracy and decision-making regarding waste management

Influence of surface characteristics on the in vitro stability and cell uptake of nanoliposomes for brain delivery

• Dushko Shalabalija,
• Ljubica Mihailova,
• Nikola Geskovski,
• Andreas Zimmer,
• Otmar Geiss,
• Sabrina Gioria,
• Diletta Scaccabarozzi and
• Marija Glavas Dodov

Beilstein J. Nanotechnol. 2026, 17, 139–158, doi:10.3762/bjnano.17.9

• set to 1.38 and 0.010, respectively. Water was set as the dispersant, the temperature was set to 25 °C, while the attenuation was set to 11. The 'general purpose (normal distribution)' was chosen as the analysis model. High-resolution automated electrophoresis of the adsorbed proteins onto

• diluted 200-fold in milli-Q water and denatured at 95 °C for 5 min in reducing condition by adding 3.5 µL of 1 M dithiothreitol (DTT) buffer solution to 100 µL of each sample buffer. After cooling, samples were loaded on the microfluidic chip for electrophoresis, in accordance with the instructions from

Development and in vitro evaluation of liposomes and immunoliposomes containing 5-fluorouracil and R-phycoerythrin as a potential phototheranostic system for colorectal cancer

• Raissa Rodrigues Camelo,
• Vivianne Cortez Sombra Vandesmet,
• Octavio Vital Baccallini,
• José de Brito Vieira Neto,
• Thais da Silva Moreira,
• Luzia Kalyne Almeida Moreira Leal,
• Claudia Pessoa,
• Daniel Giuliano Cerri,
• Maria Vitória Lopes Badra Bentley,
• Josimar O. Eloy,
• Ivanildo José da Silva Júnior and
• Raquel Petrilli

Beilstein J. Nanotechnol. 2026, 17, 97–121, doi:10.3762/bjnano.17.7

• water. Given that PBS from the original formulation remains associated with the vesicles and maintains their colloidal stability, no additional saline was required during dilution. The measurements were performed in triplicate at 25 °C using an optical 4 mW HeNe at a wavelength of 633 nm. The results (n

• and immunoliposomes were first stabilized by adding 5% glutaraldehyde for 2 h [25]. After fixation, the formulations were diluted at a ratio of 1:750 in deionized distilled water (ddH2O). A 3.0 µL aliquot of the diluted sample was deposited onto a freshly cleaved mica substrate, followed by vacuum

• occurs passively during the formation of vesicles. For water-soluble drugs, such as those used in this study, loading occurs through interactions with the intraliposomal aqueous core. For hydrophilic drugs, encapsulation efficiency tends to be low, so the drug/lipid ratio is usually lower, between 10 and

Functional surface engineering for cultural heritage protection: the role of superhydrophobic and superoleophobic coatings – a comprehensive review

• Giuseppe Cesare Lama,
• Marino Lavorgna,
• Letizia Verdolotti,
• Federica Recupido,
• Giovanna Giuliana Buonocore and
• Bharat Bhushan

Beilstein J. Nanotechnol. 2026, 17, 63–96, doi:10.3762/bjnano.17.6

• relevant when considering different threats. Water is the most pervasive menace, in both indoor and outdoor environments [52]. For stone and other inorganic materials, high porosity and surface irregularities can increase coating absorption, resulting in thicker and less uniform layers that compromise

• water-absorbent) [53], while, if in indoor environment, they may experience biological fouling (fungi or bacteria) [54][55], which might initiate bio-deterioration [56]. If the substrate is metallic, corrosion caused by water (rain when outdoor and humidity fluctuation when indoor) is the main issue

• , causing rusty surfaces due to oxygen dispersed in water or to salt residues [57]. For these reasons, much effort is devoted to developing coatings that minimize water interaction, while ensuring that substrate-dependent properties such as porosity, roughness, and coating thickness are carefully considered

Reduced graphene oxide paper electrode for lithium-ion cells – towards optimized thermal reduction

• Agata Pawłowska,
• Magdalena Baran,
• Stefan Marynowicz,
• Aleksandra Izabela Banasiak,
• Adrian Racki,
• Adrian Chlanda,
• Tymoteusz Ciuk,
• Marta Wolczko and
• Andrzej Budziak

Beilstein J. Nanotechnol. 2026, 17, 24–37, doi:10.3762/bjnano.17.3

• bending vibrations in water molecules [46]. The distinct peaks observed between 1700 and 1800 cm−1 correspond to the C=O stretching vibrations from carbonyl groups [27]. The peak near 2848 cm−1 can refer to the C–H stretching in aldehyde groups [46] and the 3013 cm−1 peak to the aromatics C(sp2)–H [46

• ]. The wavenumber shift in relation to literature data can result from the applied reduction parameters (cf. Xiong et al. [47]). The band observed in the wavenumber range of 3300–3600 cm−1 can be attributed to the O–H stretching vibrations from hydroxy groups or adsorbed water. The temperature values for

Quantitative estimation of nanoparticle/substrate adhesion by atomic force microscopy

• Aydan Çiçek,
• Markus Kratzer,
• Christian Teichert and
• Christian Mitterer

Beilstein J. Nanotechnol. 2026, 17, 1–14, doi:10.3762/bjnano.17.1

• (QMF), both with a diameter of 125 mm. In this study, only one of the three water-cooled magnetrons, equipped with a Cu target (Kurt J. Lesker, 99.999% purity) with 25.8 mm diameter and 3.2 mm thickness, was used. Prior to deposition, the base pressure in the deposition chamber was pumped down to 6

Internal 3D temperature mapping in biological systems using ratiometric light-sheet imaging and lipid-coated upconversion nanothermometers

• Dannareli Barron-Ortiz,
• Enric Pérez-Parets,
• Rubén D. Cadena-Nava,
• Emilio J. Gualda,
• Jacob Licea-Rodríguez,
• Juan Hernández-Cordero,
• Pablo Loza-Álvarez and
• Israel Rocha-Mendoza

Beilstein J. Nanotechnol. 2025, 16, 2306–2316, doi:10.3762/bjnano.16.159

• mapping in living organisms. Materials and Methods Lipid-wrapped UCNPs Due to their highly hydrophobic nature, commercial NaYF4:Yb3+/Er3+ UCNPs (Sigma-Aldrich, No. 900556 1 ML) were coated with lipids to enhance their water dispersibility. This lipid coating (UCNPs@lipids) was applied using a modified

• 100 µL of UCNPs in a round-bottomed flask. The resulting mixture was then evaporated under a constant flow of N2 gas while stirring in a circular motion for 30 min. After solvent evaporation, 2 mL of Milli-Q water were added to the flask for rehydration overnight at 4 °C. The resulting water

• -dispersible UCNPs@lipids solution had a UCNP concentration of 1 mg·mL−1 and was stored at room temperature for subsequent use and characterization. Evidence of obtaining such a water-dispersible solution was previously reported in [40]. Figure 2 compares the as-purchased nanoparticles dispersed in toluene

Improving magnetic properties of Mn- and Zn-doped core–shell iron oxide nanoparticles by tuning their size

• Dounia Louaguef,
• Ghouti Medjahdi,
• Sébastien Diliberto,
• Klaus M. Seemann,
• Thomas Gries,
• Joelle Bizeau,
• Damien Mertz,
• Eric Gaffet and
• Halima Alem

Beilstein J. Nanotechnol. 2025, 16, 2285–2295, doi:10.3762/bjnano.16.157

• -capping agents, such as oleic acid, which is commonly used during synthesis to control particle size and prevent aggregation. The broad peak observed at ≈3400 cm−1 is linked to the O–H stretching vibrations of adsorbed water or hydroxy groups on the particle surface, which is a common feature for

Visualizing nanostructures in supramolecular hydrogels: a correlative study using confocal and cryogenic scanning electron microscopy

• Shaun M. Smith,
• Ferdinando Malagreca,
• Jacqueline Hicks,
• Giuseppe Mantovani,
• David B. Amabilino,
• Christopher Parmenter and
• Lluïsa Pérez-García

Beilstein J. Nanotechnol. 2025, 16, 2274–2284, doi:10.3762/bjnano.16.156

• ; microscopies; nanostructure; supramolecular hydrogel; Introduction Hydrogels, whether based on self-assembling molecules or cross-linked polymers, are useful in fields ranging from tissue engineering to drug delivery and biosensing [1][2][3][4][5]. Their high water content and soft, porous structure make them

• diketopyrrolopyrrole bis(carboxylic acid) (DPP-BC) (Figure 1), are probed using confocal fluorescence microscopy and cryo-SEM. ZnPc is a water-soluble fluorophore with a conjugated and mainly flat macrocyclic structure, characterized by strong absorption in the red region of the visible spectrum, and has been

• previously studied within imidazolium-based gel system [19] without the methods employed here. The DPP derivative, by contrast, is a water-soluble diketopyrrolopyrrole featuring a central 2,5-dihydro-2,5-dioxo-pyrrolo[3,4-c]pyrrole core flanked at the 3- and 6-positions by thiophene rings. The lactam

Chiral plasmonic nanostructures fabricated with circularly polarized light

• Tian Qiao and
• Ming Lee Tang

Beilstein J. Nanotechnol. 2025, 16, 2245–2264, doi:10.3762/bjnano.16.154

• that the sites of Au deposition ( reduction) are the locations of electrons from the nanoparticle transferred via PVP. Researchers made similar observations when electron beam lithography resist was exposed to hot electrons from AuNRs [86]. This study found hydrogen silsesquioxane underwent water

Optical bio/chemical sensors for vitamin B₁₂ analysis in food and pharmaceuticals: state of the art, challenges, and future outlooks

• Seyed Mohammad Taghi Gharibzahedi and
• Zeynep Altintas

Beilstein J. Nanotechnol. 2025, 16, 2207–2244, doi:10.3762/bjnano.16.153

• synthesize under sunlight exposure, all other micronutrients must be obtained via dietary intake [3]. Vitamins are classified into two distinct categories, namely, water-soluble (e.g., vitamin C and vitamin B group) and fat-soluble (e.g., vitamins A, D, E, and K). Vitamin B12 (VB12) is among B-group vitamins

• ]. This water-soluble micronutrient is essential for improving brain and nervous system functions, blood cell development, bone health improvement, energy and DNA production, fertility and embryo development, control of neurological symptoms (e.g., stress, depression, dementia, and visual disturbances

• different countries, organized by the VB12 concentration threshold [70]. Initially, labs used microbiological tests to determine VB12 levels because of their favorable accuracy. These tests did not measure VB12 directly. Instead, microbiological analyses examined how certain bacteria consume this water

Ultrathin water layers on mannosylated gold nanoparticles

• Maiara A. Iriarte Alonso,
• Jorge H. Melillo,
• Silvina Cerveny,
• Yujin Tong and
• Alexander M. Bittner

Beilstein J. Nanotechnol. 2025, 16, 2183–2198, doi:10.3762/bjnano.16.151

• hydrophobic tips. While VSFG indicated preferential hydration of the dimannoside and proved conformational changes in the organic ligands, AFM provided sub-nanometer changes in particle topography due to water adsorption. In general, the dimannoside nanoparticles condense ultrathin water layers upon humidity

• increase. In contrast, we found that the water adsorption on the oligo(ethylene glycol) particles depends little on humidity. Our insights into structural changes on glyconanoparticles and the hydration properties of glycosylated particles are of application value for biosensors and help model the

• transmission of airborne viruses, such as influenza. Keywords: AFM; humidity; hydrophilicity; hydrophobicity; nanoparticles; sum frequency generation spectroscopy; viruses; water; wetting; Introduction Gold nanoparticles (AuNPs) have been a staple in biomedical and biophysical research [1][2] for almost a

Missing links in nanomaterials research impacting productivity and perceptions

• Santosh K. Tiwari and
• Nannan Wang

Beilstein J. Nanotechnol. 2025, 16, 2168–2176, doi:10.3762/bjnano.16.149

• contaminating water, air, and soil, even when strict preventive measures are in place. Moreover, the environmental pollution caused by nanomaterials after their lifecycle, along with the chemicals used in their synthesis, is much more hazardous; up to a thousand times more compared to their bulk counterparts

Microplastic pollution in Himalayan lakes: assessment, risks, and sustainable remediation strategies

• Sameeksha Rawat,
• S. M. Tauseef and
• Madhuben Sharma

Beilstein J. Nanotechnol. 2025, 16, 2144–2167, doi:10.3762/bjnano.16.148

• in the ecologically sensitive Himalayan lakes, posing a threat to biodiversity, water quality, and human habitation. These high-altitude freshwater ecosystems are being increasingly polluted through human use, tourism, glacier melt, and atmospheric deposition. Microplastic quantification in such

• pollution; nanotechnology; remediation; Review 1 Introduction The Himalayan lakes, often known as the “Water Towers of Asia,” serve an important role in biodiversity conservation, downstream hydraulic management, and supplying freshwater supplies to millions of people. Sau et al. explain that Pangong

• increasing load of MPs in inland water bodies, for example, rivers, lakes, and estuaries [5]. For South Asia, especially, high MP loads in major river systems such as the Ganges and Brahmaputra have all been driven by rapid urbanization, poor plastic waste management, and hydrological connectivity [6]. Yet

Quality by design optimization of microemulsions for topical delivery of Passiflora setacea seed oil

• Daniel T. Pereira,
• Douglas Dourado,
• Danielle T. Freire,
• Dayanne L. Porto,
• Cícero F. S. Aragão,
• Myla L. de Souza,
• Guilherme R. S. de Araujo,
• Ana Maria Costa,
• Wógenes N. Oliveira,
• Anne Sapin-Minet,
• Éverton N. Alencar and
• Eryvaldo Sócrates T. Egito

Beilstein J. Nanotechnol. 2025, 16, 2116–2131, doi:10.3762/bjnano.16.146

• address these challenges, nanotechnology-based delivery systems, particularly microemulsions (MEs), offer a promising solution. Microemulsions are thermodynamically stable, isotropic mixtures typically composed of oil, water, surfactants, and co-surfactants [6]. Their spontaneous formation, high

• incompatibility among the excipients, such as the lowering of degradation temperatures. The thermal events observed in the DTG and DSC curves correspond to the loss of free water (≈98 °C), solvation water (≈110 °C), and thermal degradation of the oil phase (≈417 °C), overlapping with the degradation profiles of

• of the MEgel could not be determined. However, NaCMC solutions exhibit negligible surface activity and typically maintain surface tension values close to that of water [48]. Rheological analysis Rheological profiling provides key insights into the behavior of formulations under applied stress or

Molecular and mechanical insights into gecko seta adhesion: multiscale simulations combining molecular dynamics and the finite element method

• Yash Jain,
• Saeed Norouzi,
• Tobias Materzok,
• Stanislav N. Gorb and
• Florian Müller-Plathe

Beilstein J. Nanotechnol. 2025, 16, 2055–2076, doi:10.3762/bjnano.16.141

• microscopy (AFM) experiments. Our investigation into how gecko keratin interacts with hydrophilic and hydrophobic substrates [12] supported the importance of the water-mediating effect [10] and elucidated mechanistic differences depending on surface chemistry. A particle-based mesoscale model of a single

• gecko keratin [11]. It also helped clarify other aspects of humidity-enhanced adhesion, revealing that keratin softening due to water uptake accounts for only a minor part of the increase in adhesion on very smooth surfaces [13]. The present paper builds on our previous research and extends the

Stereodiscrimination of guests in chiral organosilica aerogels studied by ESR spectroscopy

• Sebastian Polarz,
• Yasar Krysiak,
• Martin Wessig and
• Florian Kuhlmann

Beilstein J. Nanotechnol. 2025, 16, 2034–2054, doi:10.3762/bjnano.16.140

• , followed by crystallization. The precipitate is filtered off and washed with acetone. (The acetone phase can be used to obtain (−)-3CP). The filtrate is dissolved in water, acidified with hydrochloric acid to pH 3 and extracted three times with diethyl ether. The ether phase is dried with MgSO4, and the

Beyond the shell: exploring polymer–lipid interfaces in core–shell nanofibers to carry hyaluronic acid and β-caryophyllene

• Aline Tavares da Silva Barreto,
• Francisco Alexandrino-Júnior,
• Bráulio Soares Arcanjo,
• Paulo Henrique de Souza Picciani and
• Kattya Gyselle de Holanda e Silva

Beilstein J. Nanotechnol. 2025, 16, 2015–2033, doi:10.3762/bjnano.16.139

• inflammatory response during wound healing [32][33]. Chemically, βCp is characterized as a natural bicyclic sesquiterpene found in several plants and essential oils, and as expected for compounds of this class, it exhibits characteristic volatility and low solubility in water [34]. To address these limitations

• core removal, the fibers exhibited a filled core structure, as depicted in Figure 6A. Sequential washing with water and ethanol, followed by drying and cryofracture, effectively solubilized and removed the core material, yielding hollow fiber structures (Figure 6B). These observations confirmed the

• to increased water ingress through the pores, facilitating access to the core [58]. This possibility is also described by Wang and Xu (2018), who successfully prepared tea polyphenol-loaded porous core–shell fibers by controlling coaxial electrospinning parameters [56]. ATR-FTIR spectroscopy has been

The cement of the tube-dwelling polychaete Sabellaria alveolata: a complex composite adhesive material

• Emilie Duthoo,
• Aurélie Lambert,
• Pierre Becker,
• Carla Pugliese,
• Jean-Marc Baele,
• Arnaud Delfairière,
• Matthew J. Harrington and
• Patrick Flammang

Beilstein J. Nanotechnol. 2025, 16, 1998–2014, doi:10.3762/bjnano.16.138

• Milli-Q water drop. Antisense digoxigenin (DIG)-labelled RNA probes were synthesized with DIG RNA Labelling Kit (Roche) with T7 RNA polymerase and DIG–dUTP. In situ hybridization was performed according to the protocol of Lengerer and colleagues [30]. The RNA probes were used at a concentration of 0.2

Laser ablation in liquids for shape-tailored synthesis of nanomaterials: status and challenges

• Natalie Tarasenka

Beilstein J. Nanotechnol. 2025, 16, 1963–1997, doi:10.3762/bjnano.16.137

• formation of iron oxide nanowires was reported only in case of ablation with a 248 nm laser of iron powder suspended in methanol, while other solvents (including water, ethanol, isopropanol, and glycol) resulted in only spherical NPs. Moreover, ablation using a 532 nm laser produced spherical NPs in all the

• relatively short periods of time, produces spherical NPs that act as seeds during the growth of nonspherical nanostructures. Such approach has been demonstrated in [26] for the production of PbO nanosheets with thickness less than 15 nm by laser ablation of a lead target in water. After the initial stage

• femtosecond laser ablation of ZnSe powder in water. The transformation to nanowires, which were 100–300 nm in diameter and 50 μm long, was observed during ageing for a week. Furthermore, the authors applied air bubbling through the solution to induce change of nanowires into hollow nanotubes, which is

PEGylated lipids in lipid nanoparticle delivery dynamics and therapeutic innovation

• Peiyang Gao

Beilstein J. Nanotechnol. 2025, 16, 1914–1930, doi:10.3762/bjnano.16.133

• hydrophobic segment to act as a hydrophilic shield [80]. The rationale was that the highly water-soluble and flexible pSar chains could sterically block antibody access to the PEG domain, thereby reducing immune recognition. ELISA showed that the absorbance signal from anti-PEG IgG dropped from over 1.5 to

Targeting the vector of arboviruses Aedes aegypti with nanoemulsions based on essential oils: a review with focus on larvicidal and repellent properties

• Laryssa Ferreira do Nascimento Silva,
• Douglas Dourado,
• Thayse Silva Medeiros,
• Mariana Alice Gonzaga Gabú,
• Maria Cecilia Queiroga dos Santos,
• Daiane Rodrigues dos Santos,
• Mylena Lemos dos Santos,
• Gabriel Bezerra Faierstein,
• Rosângela Maria Rodrigues Barbosa and
• Fabio Rocha Formiga

Beilstein J. Nanotechnol. 2025, 16, 1894–1913, doi:10.3762/bjnano.16.132

• arises. In this context, natural produts such as essential oils (EOs) have been studied for their larvicidal and repellent properties against Aedes aegypti, due to the presence of compounds such as terpenoids and phenols. However, the usage of EOs is limited due to some properties such as poor water

• stress, being easily degradable or evaporated upon exposure to air, light, heat, and humidity during processing, use, or storage [27][28]. Their volatile nature, susceptibility to oxidation, and insolubility in water limit their industrial application [29]. To overcome these limitations

• ]. Furthermore, they increase the water solubility of poorly soluble compounds, improve the dispersion of essential oils in vector control, and provide a controlled release of the bioactives. Finally, these systems can be obtained at low cost and through more sustainable technologies [36]. Given these advantages

Self-assembly and adhesive properties of Pollicipes pollicipes barnacle cement protein cp19k: influence of pH and ionic strength

• Shrutika Sawant,
• Anne Marie Power and
• J. Gerard Wall

Beilstein J. Nanotechnol. 2025, 16, 1863–1872, doi:10.3762/bjnano.16.129

• 48 h. After all incubations, the protein solution was aspirated, wells were washed three times with dH2O water for 5 min each, and Coomassie Blue stain was added for 15 min, followed by three destaining steps for 5 min each. Experiments were performed in triplicate, and wells were viewed on an

Current status of using adsorbent nanomaterials for removing microplastics from water supply systems: a mini review

• Nguyen Thi Nhan and
• Tran Le Luu

Beilstein J. Nanotechnol. 2025, 16, 1837–1850, doi:10.3762/bjnano.16.127

• Nguyen Thi Nhan Tran Le Luu Master Program in Water Technology, Reuse and Management, Vietnamese German University, Ho Chi Minh City, Vietnam 10.3762/bjnano.16.127 Abstract The widespread use of plastic has led to microplastics (MPs) being released in many water sources. MP contamination in water

• supply systems is a global concern due to their persistence and ability to adsorb toxic pollutants. Despite having effectiveness, conventional water treatment processes still have limited efficiency in removing MPs, especially smaller particles. Thus, it requires researchers to develop effective and

• sustainable strategies to deal with this matter. Many studies have shown that adsorbent nanomaterials have potential for the removal of MPs from water. This review evaluates the current status of using adsorbent nanomaterials in removing MPs from water supply systems. It discusses the occurrences and removal