Search results

Search for "anisotropy" in Full Text gives 69 result(s) in Beilstein Journal of Organic Chemistry.

Unraveling aromaticity: the dual worlds of pyrazole, pyrazoline, and 3D carborane

  • Zahra Noori,
  • Miquel Solà,
  • Clara Viñas,
  • Francesc Teixidor and
  • Jordi Poater

Beilstein J. Org. Chem. 2025, 21, 412–420, doi:10.3762/bjoc.21.29

Graphical Abstract
  • computed with the ESI-3D program using AIM partition of space [75][76]. The anisotropy of the induced current density (AICD) plots have been computed at the same level of theory [77]. Current density maps have been computed by means of the SYSMOIC package [78][79][80], at the same level of theory. Finally
PDF
Album
Supp Info
Full Research Paper
Published 21 Feb 2025

Oxidation of [3]naphthylenes to cations and dications converts local paratropicity into global diatropicity

  • Abel Cárdenas,
  • Zexin Jin,
  • Yong Ni,
  • Jishan Wu,
  • Yan Xia,
  • Francisco Javier Ramírez and
  • Juan Casado

Beilstein J. Org. Chem. 2025, 21, 277–285, doi:10.3762/bjoc.21.20

Graphical Abstract
  • shift (NICS) calculations and anisotropy of the current induced density (ACID) plots, as they evidenced the presence of a perimetral diatropic global ring current upon oxidation. Keywords: ACID; aromaticity; force constants; NICS; spectroscopy; Introduction Since the discovery of conjugated polymers
  • . In this case, the CBDs act as stoppers for whole innermost electron delocalization Anisotropy of the current induced density (ACID) The NICS analysis of the precedent paragraph is therefore consistent with the existence of an emergent global diatropic ring current in m-12+ along the entire molecular
PDF
Album
Supp Info
Full Research Paper
Published 05 Feb 2025

Photoredox-catalyzed intramolecular nucleophilic amidation of alkenes with β-lactams

  • Valentina Giraldi,
  • Giandomenico Magagnano,
  • Daria Giacomini,
  • Pier Giorgio Cozzi and
  • Andrea Gualandi

Beilstein J. Org. Chem. 2024, 20, 2461–2468, doi:10.3762/bjoc.20.210

Graphical Abstract
  • chemical shifts of these protons in the two isomers could be attributed to the influence of the anisotropy of the neighboring carboxy group of the β-lactam and could be correlated with the configuration at the bridgehead stereocenter [46]. This analysis revealed the preferred formation of the trans- over
PDF
Album
Supp Info
Full Research Paper
Published 01 Oct 2024

Switchable molecular tweezers: design and applications

  • Pablo Msellem,
  • Maksym Dekthiarenko,
  • Nihal Hadj Seyd and
  • Guillaume Vives

Beilstein J. Org. Chem. 2024, 20, 504–539, doi:10.3762/bjoc.20.45

Graphical Abstract
  • reversible Zn-induced closing was also achieved. Despite the magnetic anisotropy of Mn(III), no single molecule magnet behavior was observed in either closed form. Nevertheless, this system constitutes a promising example of dual switchable molecular tweezers that can be addressed by two orthogonal stimuli
PDF
Album
Review
Published 01 Mar 2024

Spatial arrangements of cyclodextrin host–guest complexes in solution studied by 13C NMR and molecular modelling

  • Konstantin Lebedinskiy,
  • Ivan Barvík,
  • Zdeněk Tošner,
  • Ivana Císařová,
  • Jindřich Jindřich and
  • Radim Hrdina

Beilstein J. Org. Chem. 2024, 20, 331–335, doi:10.3762/bjoc.20.33

Graphical Abstract
  • crystallization of host–guest complexes and their crystallographic analysis. Keywords: anisotropy; 13C NMR; cyclodextrin; host–guest complexes; Introduction Complexation of organic and inorganic compounds with α-, β-, or γ-cyclodextrins and their derivatives [1] is an established tool used in medicine for drug
  • anisotropy of the chiral cavity is expressed by differences in the magnetic shielding of prochiral atoms, resulting in signal splitting of the prochiral carbons of the guest molecule in 13C NMR spectra. Adamantan-2-amine hydrochloride was used as a model guest molecule containing three sets of prochiral
PDF
Album
Supp Info
Full Research Paper
Published 20 Feb 2024

Charge carrier transport in perylene-based and pyrene-based columnar liquid crystals

  • Alessandro L. Alves,
  • Simone V. Bernardino,
  • Carlos H. Stadtlober,
  • Edivandro Girotto,
  • Giliandro Farias,
  • Rodney M. do Nascimento,
  • Sergio F. Curcio,
  • Thiago Cazati,
  • Marta E. R. Dotto,
  • Juliana Eccher,
  • Leonardo N. Furini,
  • Hugo Gallardo,
  • Harald Bock and
  • Ivan H. Bechtold

Beilstein J. Org. Chem. 2023, 19, 1755–1765, doi:10.3762/bjoc.19.128

Graphical Abstract
  • ), organic light-emitting diodes (OLEDs) and sensors [1][2]. Columnar liquid crystals are attractive due to their solution processability and their self-organization in highly anisotropic supramolecular architectures, which favors the mainly one-dimensional migration of charge carriers with an anisotropy of
PDF
Album
Supp Info
Full Research Paper
Published 16 Nov 2023

Preparation of β-cyclodextrin-based dimers with selectively methylated rims and their use for solubilization of tetracene

  • Konstantin Lebedinskiy,
  • Volodymyr Lobaz and
  • Jindřich Jindřich

Beilstein J. Org. Chem. 2022, 18, 1596–1606, doi:10.3762/bjoc.18.170

Graphical Abstract
  • the spacer is a less polar substituent than an oxygen atom. It justifies the magnetic anisotropy of the space surrounding the aromatic ring, leading to some specific signals becoming isolated and easily distinguishable. For example, a clearly defined H6 signal from the glucose unit A bearing the
PDF
Album
Supp Info
Full Research Paper
Published 25 Nov 2022

Inductive heating and flow chemistry – a perfect synergy of emerging enabling technologies

  • Conrad Kuhwald,
  • Sibel Türkhan and
  • Andreas Kirschning

Beilstein J. Org. Chem. 2022, 18, 688–706, doi:10.3762/bjoc.18.70

Graphical Abstract
  • reaching the nanoscale. The energy barrier of such superparamagnetic nanoparticles to reverse magnetization is directly related to magnetic anisotropy and particle volume [19][20]. In external magnetic fields, these spins rotate in the direction of the magnetic field direction and the axis of magnetic
  • moment fluctuates along the magnetocrystalline anisotropy axis. Néel has described the relationship between the relaxation time of the thermal fluctuations of the magnetic moments of the individual domains and the uniaxial anisotropy. In Néel relaxation, the energy barrier for the remanence of
PDF
Album
Review
Published 20 Jun 2022

Unsaturated fatty acids and a prenylated tryptophan derivative from a rare actinomycete of the genus Couchioplanes

  • Shun Saito,
  • Kanji Indo,
  • Naoya Oku,
  • Hisayuki Komaki,
  • Masashi Kawasaki and
  • Yasuhiro Igarashi

Beilstein J. Org. Chem. 2021, 17, 2939–2949, doi:10.3762/bjoc.17.203

Graphical Abstract
  • -octadienoic acid (5), and one prenylated tryptophan derivative, 6-(3,3-dimethylallyl)-N-acetyl-ʟ-tryptophan (6). The enantiomer ratio of 4 was determined to be approximately S/R = 56:44 by a recursive application of Trost’s chiral anisotropy analysis and chiral HPLC analysis of its methyl ester. Compounds 1–5
  • mixture (Supporting Information File 1, Figure S25). Furthermore, the slightly excessive 4'a and 4'c were identified to be MPA derivatives of (S)-4, and hence less excessive 4'b and 4'd to be those of (R)-4, by recursive application of Trost’s chiral anisotropy rule to the 1H chemical shift differences
  • -7 to C-1' and from H-1' to C-6. The absolute configuration was determined by chiral anisotropy analysis after derivatization with each of the phenylglycine methyl ester (PGME) enantiomers [27], which gave positive ΔδH(S-R) values for NH-1, H-2, H-4, H-5 and H-8 and negative values for H-9, NH-11 and
PDF
Album
Supp Info
Full Research Paper
Published 16 Dec 2021

Effect of a twin-emitter design strategy on a previously reported thermally activated delayed fluorescence organic light-emitting diode

  • Ettore Crovini,
  • Zhen Zhang,
  • Yu Kusakabe,
  • Yongxia Ren,
  • Yoshimasa Wada,
  • Bilal A. Naqvi,
  • Prakhar Sahay,
  • Tomas Matulaitis,
  • Stefan Diesing,
  • Ifor D. W. Samuel,
  • Wolfgang Brütting,
  • Katsuaki Suzuki,
  • Hironori Kaji,
  • Stefan Bräse and
  • Eli Zysman-Colman

Beilstein J. Org. Chem. 2021, 17, 2894–2905, doi:10.3762/bjoc.17.197

Graphical Abstract
  • ) of the device. A compound will emit light perpendicular to its transition dipole moment (TDM), quantified by the anisotropy factor, a. Controlling the orientation of the TDM to lie horizontally in the film (where 1 − a is the fraction of horizontally aligned TDMs) will lead to a maximized amount of
  • nearly complete horizontal orientation in a wide number of host matrices. The best combination of properties was obtained in mCBP as a host, with the photoluminescence maximum wavelength, λPL of 479 nm, ΦPL of 70%, and a τd of 121.1 μs for the vacuum-deposited doped film. The anisotropy factor (a) in 5
  • . Considering the high degree of horizontal orientation that ICzTRZ already showed in vacuum-deposited films (anisotropy factor of 0.09 in 10 wt % film of mCBP) and the high molecular weight of DICzTRZ, we hypothesized that DICzTRZ may also present horizontal orientation in the film and subsequently improve
PDF
Album
Supp Info
Full Research Paper
Published 08 Dec 2021

Synthesis of new bile acid-fused tetrazoles using the Schmidt reaction

  • Dušan Đ. Škorić,
  • Olivera R. Klisurić,
  • Dimitar S. Jakimov,
  • Marija N. Sakač and
  • János J. Csanádi

Beilstein J. Org. Chem. 2021, 17, 2611–2620, doi:10.3762/bjoc.17.174

Graphical Abstract
  • observations about the preferred migration of the more substituted carbon atom during the Schmidt reaction [49]. Also, a retention of configuration at the C-13 position was confirmed by NOE NMR experiments. The chemical shift of some protons in compounds 13 and 14 exhibited effects of magnetic anisotropy from
  • configuration at C-8 was confirmed. Similarly to C-homotetrazoles, magnetic anisotropy effects of the aromatic tetrazole ring are obvious in 1H NMR spectra of compounds 17 and 18. For example, the chemical shift of the H-4α proton is much lower than expected (0.45 ppm). Interestingly, we noticed that crystals
PDF
Album
Supp Info
Full Research Paper
Published 20 Oct 2021

Cryogels: recent applications in 3D-bioprinting, injectable cryogels, drug delivery, and wound healing

  • Luke O. Jones,
  • Leah Williams,
  • Tasmin Boam,
  • Martin Kalmet,
  • Chidubem Oguike and
  • Fiona L. Hatton

Beilstein J. Org. Chem. 2021, 17, 2553–2569, doi:10.3762/bjoc.17.171

Graphical Abstract
  • [20]. This finding was further reiterated by Sen et al., who also explored heterogeneous pore size distribution for tissue engineering applications [21]. Cryostructuring, including directional freezing of cryogels, has been used to achieve varying degrees of porosity and aligned porosity or anisotropy
PDF
Album
Review
Published 14 Oct 2021

19F NMR as a tool in chemical biology

  • Diana Gimenez,
  • Aoife Phelan,
  • Cormac D. Murphy and
  • Steven L. Cobb

Beilstein J. Org. Chem. 2021, 17, 293–318, doi:10.3762/bjoc.17.28

Graphical Abstract
  • NMR spectroscopy for drug screening has also evolved in the last decade to become a key tool to study the binding of drug candidates to target proteins. 19F NMR-based screening, which was developed by Dalvit et al., includes fluorine chemical shift anisotropy and exchange for screening (FAXS) [38
PDF
Album
Review
Published 28 Jan 2021

Diels–Alder reaction of β-fluoro-β-nitrostyrenes with cyclic dienes

  • Savva A. Ponomarev,
  • Roman V. Larkovich,
  • Alexander S. Aldoshin,
  • Andrey A. Tabolin,
  • Sema L. Ioffe,
  • Jonathan Groß,
  • Till Opatz and
  • Valentine G. Nenajdenko

Beilstein J. Org. Chem. 2021, 17, 283–292, doi:10.3762/bjoc.17.27

Graphical Abstract
  • probably such significant difference in the chemical shifts can be explained by the double bond anisotropy of the norbornene molecule [60]. The stereochemical assignments are in full accordance with the values of vicinal (3JH6-F and 3JH1-H6) and long-range coupling constants (4JH6-H7b). According to the
PDF
Album
Supp Info
Full Research Paper
Published 27 Jan 2021

Tuning the solid-state emission of liquid crystalline nitro-cyanostilbene by halogen bonding

  • Subrata Nath,
  • Alexander Kappelt,
  • Matthias Spengler,
  • Bibhisan Roy,
  • Jens Voskuhl and
  • Michael Giese

Beilstein J. Org. Chem. 2021, 17, 124–131, doi:10.3762/bjoc.17.13

Graphical Abstract
  • temperature, which indicates that the strength of the halogen bond is not the only contributor to the mesomorphic behaviour of the halogen-bonded materials. The change in the electronic anisotropy by unsymmetrical substitution with fluorine as present in F3Az will also have an impact on the dispersion
PDF
Album
Supp Info
Letter
Published 14 Jan 2021

NMR Spectroscopy of supramolecular chemistry on protein surfaces

  • Peter Bayer,
  • Anja Matena and
  • Christine Beuck

Beilstein J. Org. Chem. 2020, 16, 2505–2522, doi:10.3762/bjoc.16.203

Graphical Abstract
  • the lines and decreases the signal intensities even more. In addition, the stabilization of the 14-3-3 peptide interaction in the presence of the ligand was confirmed by biochemical assays such as isothermal titration calorimetry (ITC) and fluorescence anisotropy. On a quest for modulators of 14-3-3
  • for measuring binding affinities, such as isothermal titration calorimetry (ITC) or fluorescence anisotropy/polarization, are only able to provide an averaged KD. Outlook In the last two decades, additional NMR methods have been developed to extend the size limits of NMR spectroscopy to very large
PDF
Album
Review
Published 09 Oct 2020

Three new O-isocrotonyl-3-hydroxybutyric acid congeners produced by a sea anemone-derived marine bacterium of the genus Vibrio

  • Dandan Li,
  • Enjuro Harunari,
  • Tao Zhou,
  • Naoya Oku and
  • Yasuhiro Igarashi

Beilstein J. Org. Chem. 2020, 16, 1869–1874, doi:10.3762/bjoc.16.154

Graphical Abstract
  • -hydroxybutyric acid (4). The structures of 1–3 were established by NMR spectroscopy and mass spectrometry, coupled with anisotropy-based chiral analysis, revealing the same R-configuration for all congeners 1–4. The compounds 1–4 were weakly growth-inhibitory against a marine fish ulcer pathogenic bacterium
  • , respectively (Figure 1). A database search identified the planar structure of 4 in a patent that described 5 (Figure 1) from marine obligate Vibrio sp. C-984 [9]. To determine the absolute configuration of C3 in 1–4, an anisotropy-based chiral analysis using a chiral derivatization reagent, phenylglycine
  • (Figure 3a). Note that the sign distribution of the Δδ(S − R) values in β,β-substituted carboxylic acids is inverted from that observed in the α,α-substituted counterparts (Figure 3b) because the PGME anisotropy group is flipped upside down due to the insertion of an extra methylene group between the
PDF
Album
Supp Info
Full Research Paper
Published 29 Jul 2020

Heterogeneous photocatalysis in flow chemical reactors

  • Christopher G. Thomson,
  • Ai-Lan Lee and
  • Filipe Vilela

Beilstein J. Org. Chem. 2020, 16, 1495–1549, doi:10.3762/bjoc.16.125

Graphical Abstract
  • conjugation and polarisation of the surrounding medium, which is enhanced by low εr(ω) values [115][116][117][118]. The charge is transported in organic materials by “hopping” between the quantum states. The amorphous nature of most polymers produces a low symmetry and anisotropy for the charge transport
PDF
Album
Review
Published 26 Jun 2020

Synthesis of organic liquid crystals containing selectively fluorinated cyclopropanes

  • Zeguo Fang,
  • Nawaf Al-Maharik,
  • Peer Kirsch,
  • Matthias Bremer,
  • Alexandra M. Z. Slawin and
  • David O’Hagan

Beilstein J. Org. Chem. 2020, 16, 674–680, doi:10.3762/bjoc.16.65

Graphical Abstract
  • negative dielectric anisotropy. The study gives some guidance into effective structure–property relationships for the design of LCs containing selectively fluorinated cyclopropane motifs. Keywords: dielectric anisotropy; difluorocarbene; organic liquid crystals; selectively fluorinated cyclopropanes
  • the requirements for different LCD technologies. For the traditional twisted nematic (TN) LCD technology, devices require liquid crystals with display positive dielectric anisotropy by which the molecular dipole moment is oriented parallel to the long axis of the molecule, while for the current
  • vertical alignment (VA) LCD technology, liquid crystals with negative dielectric anisotropy are required [3]. Fluorine, as the most electronegative atom, forms stable bonds to carbon and can thus induce polarity. It is also attractive as a design feature due to the low polarizability of the C–F bond
PDF
Album
Supp Info
Full Research Paper
Published 14 Apr 2020

Synthesis and circularly polarized luminescence properties of BINOL-derived bisbenzofuro[2,3-b:3’,2’-e]pyridines (BBZFPys)

  • Ryo Takishima,
  • Yuji Nishii,
  • Tomoaki Hinoue,
  • Yoshitane Imai and
  • Masahiro Miura

Beilstein J. Org. Chem. 2020, 16, 325–336, doi:10.3762/bjoc.16.32

Graphical Abstract
  • Cotton signals characteristic to axially chiral molecules. In all cases, the (S)- and (R)-enantiomers were evidently mirror images of each other while the anisotropy factors gabs are relatively small and in the range of 10−4 to 10−7. The spectral shapes of 3a–c and 4a–c were respectively comparable
PDF
Album
Supp Info
Full Research Paper
Published 06 Mar 2020

Synthesis, liquid crystalline behaviour and structure–property relationships of 1,3-bis(5-substituted-1,3,4-oxadiazol-2-yl)benzenes

  • Afef Mabrouki,
  • Malek Fouzai,
  • Armand Soldera,
  • Abdelkader Kriaa and
  • Ahmed Hedhli

Beilstein J. Org. Chem. 2020, 16, 149–158, doi:10.3762/bjoc.16.17

Graphical Abstract
  • the fluorine atom leads to a subtle modification of properties such as melting point, mesophase morphology, transition temperatures, optical anisotropy, dielectric anisotropy, and visco-elasticity [5][6][7][8][9][10]. Therefore, many fluorinated liquid crystals have been prepared, and the fluoro
  • lead on a deep study in order to investigate other parameters such as response time, viscosity and dielectric anisotropy. DSC thermograms of fluorinated compounds 2b, 4a and 4b recorded at 5 °C/mn at heating (down traces) and cooling (top traces) cycles. Optical texture (×10) of liquid crystal phase
PDF
Album
Supp Info
Full Research Paper
Published 31 Jan 2020

Unexpected one-pot formation of the 1H-6a,8a-epiminotricyclopenta[a,c,e][8]annulene system from cyclopentanone, ammonia and dimethyl fumarate. Synthesis of highly strained polycyclic nitroxide and EPR study

  • Sergey A. Dobrynin,
  • Igor A. Kirilyuk,
  • Yuri V. Gatilov,
  • Andrey A. Kuzhelev,
  • Olesya A. Krumkacheva,
  • Matvey V. Fedin,
  • Michael K. Bowman and
  • Elena G. Bagryanskaya

Beilstein J. Org. Chem. 2019, 15, 2664–2670, doi:10.3762/bjoc.15.259

Graphical Abstract
  • interaction (hfi) anisotropy of the NO group by librational motion, and (ii) modulation of the hfi with other nuclei in the radical by rotation of the groups containing those nuclei (e.g., rotation of methyl groups). The temperature dependence of spin relaxation reveals the relevant mechanism. For comparison
  • thermally activated rotation of their methyl groups becomes rapid. Above 140 K this rotation is rapid enough to average the hfi anisotropy and to cause some decrease in the phase relaxation rates. Finally, at T > 220 K the librational motion of the NO group dominates phase relaxation and causes the
PDF
Album
Supp Info
Full Research Paper
Published 07 Nov 2019

Nanopatterns of arylene–alkynylene squares on graphite: self-sorting and intercalation

  • Tristan J. Keller,
  • Joshua Bahr,
  • Kristin Gratzfeld,
  • Nina Schönfelder,
  • Marcin A. Majewski,
  • Marcin Stępień,
  • Sigurd Höger and
  • Stefan-S. Jester

Beilstein J. Org. Chem. 2019, 15, 1848–1855, doi:10.3762/bjoc.15.180

Graphical Abstract
  • molecules on Au(111)) [34][35]. In addition to 1a, we studied 1b carrying (long) hexadecyloxy (OC16H33) and (short) hexyloxy (OC6H13) side chains, so that the anisotropy of the molecule is slightly increased as compared to 1a. Compound 1b assembles (at a concentration of 5 × 10−7 M) into an oblique pattern
PDF
Album
Supp Info
Full Research Paper
Published 02 Aug 2019

Reversible end-to-end assembly of selectively functionalized gold nanorods by light-responsive arylazopyrazole–cyclodextrin interaction

  • Maximilian Niehues,
  • Patricia Tegeder and
  • Bart Jan Ravoo

Beilstein J. Org. Chem. 2019, 15, 1407–1415, doi:10.3762/bjoc.15.140

Graphical Abstract
  • , shape and chemical environment giving rise to different SPR band wavelengths [6][7][8]. Especially gold nanorods (AuNR) are of interest because of their good synthetic availability and their unique optical properties. Due to their anisotropy AuNR possess a transversal SPR (TSPR) band in the visible and
PDF
Album
Supp Info
Full Research Paper
Published 26 Jun 2019

Design of a double-decker coordination cage revisited to make new cages and exemplify ligand isomerism

  • Sagarika Samantray,
  • Sreenivasulu Bandi and
  • Dillip K. Chand

Beilstein J. Org. Chem. 2019, 15, 1129–1140, doi:10.3762/bjoc.15.109

Graphical Abstract
  • respective signals of 1a. The observed downfield shift of the Hf signal in 2a is complexation-induced and found to have a unique position. The downfield shift of the Hg signal in 2a could not be induced by complexation and is best described by considering an anisotropy effect of the nearby carbonyl groups
PDF
Album
Supp Info
Full Research Paper
Published 21 May 2019
Other Beilstein-Institut Open Science Activities