Synthesis of oligonucleotides on a soluble support

• Harri Lönnberg

Beilstein J. Org. Chem. 2017, 13, 1368–1387, doi:10.3762/bjoc.13.134

• . Conventional ammonolysis was used for the release from support and removal of base and phosphate protections. By this approach, a 15-mer phosphorothioate ODN (sequence not given, one G coupled as a monomer) was synthesized in 58% overall yield. The development of new materials that allow nanofiltration in

Mechanochemistry-assisted synthesis of hierarchical porous carbons applied as supercapacitors

• Desirée Leistenschneider,
• Nicolas Jäckel,
• Felix Hippauf,
• Volker Presser and
• Lars Borchardt

Beilstein J. Org. Chem. 2017, 13, 1332–1341, doi:10.3762/bjoc.13.130

• Desiree Leistenschneider Nicolas Jackel Felix Hippauf Volker Presser Lars Borchardt Institute of Inorganic Chemistry, Technische Universität Dresden, Dresden, Germany INM - Leibniz Institute for New Materials & Saarland University, Saarbrücken, Germany Department of Materials Science and

Biomimetic molecular design tools that learn, evolve, and adapt

• David A Winkler

Beilstein J. Org. Chem. 2017, 13, 1288–1302, doi:10.3762/bjoc.13.125

• quantitatively predict the likely attachment of several pathogens simultaneously [47]. The research showed that models to predict attachment of an even broader range of pathogens would be possible, accelerating discovery of new materials with superior performance in medical devices. Adaptive evolutionary design

• evolutionary methods can be efficiently coupled with AI so that systems for the discovery of new materials become adaptive learning systems, the implications for the progress of science and technology (and employment) are massive and unpredictable. Such developments are already occurring in other fields, with

Interactions between shape-persistent macromolecules as probed by AFM

• Johanna Blass,
• Jessica Brunke,
• Franziska Emmerich,
• Cédric Przybylski,
• Vasil M. Garamus,
• Artem Feoktystov,
• Roland Bennewitz,
• Gerhard Wenz and
• Marcel Albrecht

Beilstein J. Org. Chem. 2017, 13, 938–951, doi:10.3762/bjoc.13.95

• Johanna Blass Jessica Brunke Franziska Emmerich Cedric Przybylski Vasil M. Garamus Artem Feoktystov Roland Bennewitz Gerhard Wenz Marcel Albrecht INM-Leibniz-Institute for New Materials, Saarland University, Campus D 2.2, D-66123 Saarbrücken, Germany Physics Department, Saarland University, Campus

Molecular-level architectural design using benzothiadiazole-based polymers for photovoltaic applications

• Vinila N. Viswanathan,
• Arun D. Rao,
• Upendra K. Pandey,
• Arul Varman Kesavan and
• Praveen C. Ramamurthy

Beilstein J. Org. Chem. 2017, 13, 863–873, doi:10.3762/bjoc.13.87

• recently reaching remarkable PCEs of up to 11.7% [5][6][7]. However, the diversity of monomeric units and the numerous available reports on the structural complexity of D–A–D-conjugated p-type polymers indicate that there is still need for new materials which can further improve the performance of OPV

Dynamics and interactions of ibuprofen in cyclodextrin nanosponges by solid-state NMR spectroscopy

• Monica Ferro,
• Franca Castiglione,
• Nadia Pastori,
• Carlo Punta,
• Lucio Melone,
• Walter Panzeri,
• Barbara Rossi,
• Francesco Trotta and
• Andrea Mele

Beilstein J. Org. Chem. 2017, 13, 182–194, doi:10.3762/bjoc.13.21

• reported matched the information from powder X-ray diffraction profiles. Keywords: cross-polarization; cyclodextrin; ibuprofen; nanosponges; solid-state NMR; Introduction In the last ten years cyclodextrin nanosponges (CDNS) polymer materials received great attention as promising new materials in several

Organofluorine chemistry: Difluoromethylene motifs spaced 1,3 to each other imparts facial polarity to a cyclohexane ring

• Mathew J. Jones,
• Ricardo Callejo,
• Alexandra M. Z. Slawin,
• Michael Bühl and
• David O'Hagan

Beilstein J. Org. Chem. 2016, 12, 2823–2827, doi:10.3762/bjoc.12.281

• attractive for drug discovery research and new materials [18]. In our own lab we have been exploring the synthesis and properties of differently fluorinated aliphatic structures based on the cyclopentane (1) and cyclohexane (2 and 3) rings, compounds which can show quite large dipole moments depending on the

High performance p-type molecular electron donors for OPV applications via alkylthiophene catenation chromophore extension

• Paul B. Geraghty,
• Calvin Lee,
• Jegadesan Subbiah,
• Wallace W. H. Wong,
• James L. Banal,
• Mohammed A. Jameel,
• Trevor A. Smith and
• David J. Jones

Beilstein J. Org. Chem. 2016, 12, 2298–2314, doi:10.3762/bjoc.12.223

• -dialdehydes 14, Scheme 5, which were purified by a combination of silica chromatography and size exclusion chromatography (SEC). A final Knoevenagel condensation coupling the BXx-dialdehydes with N-hexyl-rhodanine resulted in the required series of products, both BXR and BTxR. The new materials have been

• harvesting. It is important for commercialization of printed BHJ devices that any active layer can withstand the requirements of a printing process, which normally requires a drying or curing step for printed electrodes of >80 °C. To evaluate our new materials for possible translation to a printing process

• films of our BXxR materials to better understand the changes observed and these will be reported in due course. All the new materials have been tested as electron donors in OPV devices with PC71BM as the acceptor with thick active layers (approx. 250 nm). The preliminary results show interesting

Hydroxy-functionalized hyper-cross-linked ultra-microporous organic polymers for selective CO₂ capture at room temperature

• Partha Samanta,
• Priyanshu Chandra and
• Sujit K. Ghosh

Beilstein J. Org. Chem. 2016, 12, 1981–1986, doi:10.3762/bjoc.12.185

• ]. In terms of surface area, tuneable porosity and feasible host–guest interaction, MOFs have scored over other above mentioned porous materials [6]. But the less hydrolytic stability of metal-organic frameworks limits their real time application [7][8]. So the search for new materials having high

• polymers have been applied in the field of gas storage, catalysis, separation and recently also in CO2 capture [29][30][31][32]. The increasing environmental pollution due to carbon dioxide, urges us to develop new materials with high stability, which are cost-effective and demonstrate a high efficiency in

Cp₂TiCl/D₂O/Mn, a formidable reagent for the deuteration of organic compounds

• Antonio Rosales and
• Ignacio Rodríguez-García

Beilstein J. Org. Chem. 2016, 12, 1585–1589, doi:10.3762/bjoc.12.154

• cyclization using reagents that are cheap, abundant and environmentally friendly. Certainly, this new methodology of deuteration will contribute to the synthesis of new deuterated organic compounds with applications as internal standards, pharmaceutical drugs and new materials, among others. Conclusion In

My maize and blue brick road to physical organic chemistry in materials

• Anne J. McNeil

Beilstein J. Org. Chem. 2016, 12, 229–238, doi:10.3762/bjoc.12.24

• photobleaching, which is problematic for solid-state applications of conjugated polymers. Working with Tim I learned that new materials are interesting if they offer new properties, a lesson that still influences my research today. I learned how to manage my efforts, including when to stop working on

Polydisperse methyl β-cyclodextrin–epichlorohydrin polymers: variable contact time ¹³C CP-MAS solid-state NMR characterization

• Isabelle Mallard,
• Davy Baudelet,
• Franca Castiglione,
• Monica Ferro,
• Walter Panzeri,
• Enzio Ragg and
• Andrea Mele

Beilstein J. Org. Chem. 2015, 11, 2785–2794, doi:10.3762/bjoc.11.299

• different amounts of imprinting agent, as in the present case. We herein propose an approach based on solid-state 13C NMR techniques such as variable contact time cross-polarization magic angle spinning with dipolar decoupling (VCP-MAS) to describe these new materials. The dynamics of cross-polarization can

• be conveniently exploited to fingerprint the new materials and to provide information for tailored synthesis. Results and Discussion The molecular imprinting technique allows the introduction of a molecular memory for drugs [29][30] or volatile organic compounds [31][32]. This selective recognition

Synthesis and photophysical characteristics of polyfluorene polyrotaxanes

• Aurica Farcas,
• Giulia Tregnago,
• Ana-Maria Resmerita,
• Pierre-Henri Aubert and
• Franco Cacialli

Beilstein J. Org. Chem. 2015, 11, 2677–2688, doi:10.3762/bjoc.11.288

• moieties into zeolites [25], nanochannels [26], or by wrapping with amylose [27]. The past decade has witnessed remarkable innovations and progress in polymer science, including the field of supramolecular science as a complementary field, which offers great opportunity for new concepts, new materials with

Cu(I)-catalyzed N,N’-diarylation of natural diamines and polyamines with aryl iodides

• Svetlana P. Panchenko,
• Alexei D. Averin,
• Maksim V. Anokhin,
• Olga A. Maloshitskaya and
• Irina P. Beletskaya

Beilstein J. Org. Chem. 2015, 11, 2297–2305, doi:10.3762/bjoc.11.250

• Russian Academy of Sciences program “Elaboration of the methods for the synthesis of chemical compounds and construction of new materials”.

A new approach to ferrocene derived alkenes via copper-catalyzed olefination

• Vasily M. Muzalevskiy,
• Aleksei V. Shastin,
• Alexandra D. Demidovich,
• Namiq G. Shikhaliev,
• Abel M. Magerramov,
• Victor N. Khrustalev,
• Rustem D. Rakhimov,
• Sergey Z. Vatsadze and
• Valentine G. Nenajdenko

Beilstein J. Org. Chem. 2015, 11, 2072–2078, doi:10.3762/bjoc.11.223

• place of the target molecule is of current interest in modern synthetic chemistry [1]. From this point of view, the development of ferrocene-based molecules as crucial fragments of new materials and novel pharmacological entities is of great importance. Indeed, since the discovery of ferrocene [2] and

A facile synthetic route to benzimidazolium salts bearing bulky aromatic N-substituents

• Gabriele Grieco,
• Olivier Blacque and
• Heinz Berke

Beilstein J. Org. Chem. 2015, 11, 1656–1666, doi:10.3762/bjoc.11.182

• tunable, strongly binding ligand units in complexes in the search for new materials [1][2][3][4][5] and for catalysts of homogeneous catalysis [6][7][8][9][10]. Besides that NHCs have great potential in organocatalysis [11][12][13][14][15], their electronic properties, σ-donor ability and π-back donation

Terminal lipophilization of a unique DNA dodecamer by various nucleolipid headgroups: Their incorporation into artificial lipid bilayers and hydrodynamic properties

• Emma Werz and
• Helmut Rosemeyer

Beilstein J. Org. Chem. 2015, 11, 913–929, doi:10.3762/bjoc.11.103

• Emma Werz Helmut Rosemeyer Organic Chemistry I - Bioorganic Chemistry, Institute of Chemistry of New Materials, University of Osnabrück, Barbarastr. 7, 49069 Osnabrück, Germany Ionovation GmbH, Westerbreite 7, 49078 Osnabrück, Germany 10.3762/bjoc.11.103 Abstract A series of six cyanine-5-labeled

Regulation of integrin and growth factor signaling in biomaterials for osteodifferentiation

• Qiang Wei,
• Theresa L. M. Pohl,
• Anja Seckinger,
• Joachim P. Spatz and
• Elisabetta A. Cavalcanti-Adam

Beilstein J. Org. Chem. 2015, 11, 773–783, doi:10.3762/bjoc.11.87

• Qiang Wei Theresa L. M. Pohl Anja Seckinger Joachim P. Spatz Elisabetta A. Cavalcanti-Adam Department of Biophysical Chemistry, Institute for Physical Chemistry, University of Heidelberg, INF 253, 69120 Heidelberg, Germany Department of New Materials and Biosystems, Max-Planck Institute for

CO₂ Chemistry

• Thomas E. Müller and
• Walter Leitner

Beilstein J. Org. Chem. 2015, 11, 675–677, doi:10.3762/bjoc.11.76

• employed in the production of new materials and chemicals. We are highly grateful to the authors for their excellent contributions towards making this Thematic Series as successful as the previous editions. Thomas E. Müller and Walter Leitner Aachen, April 2015 The carbon dioxide molecule. Examples of

Bis(vinylenedithio)tetrathiafulvalene analogues of BEDT-TTF

• Erdal Ertas,
• İlknur Demirtas and
• Turan Ozturk

Beilstein J. Org. Chem. 2015, 11, 403–415, doi:10.3762/bjoc.11.46

• coupling methods [45][46]. Depending on the presence of electron-withdrawing groups on the TTF, they exhibit various oxidation potential ranges [15][26]. Recently, TTF and analogues have received widespread attention involving the development of new materials by using various anions to form different

Matsuda–Heck reaction with arenediazonium tosylates in water

• Ksenia V. Kutonova,
• Marina E. Trusova,
• Andrey V. Stankevich,
• Pavel S. Postnikov and
• Victor D. Filimonov

Beilstein J. Org. Chem. 2015, 11, 358–362, doi:10.3762/bjoc.11.41

• Chemistry of New Materials NAS Belarus, 220141, Minsk, Belarus Department of General and Inorganic Chemistry, National Research Tomsk Polytechnic University, 634050 Tomsk, Russia 10.3762/bjoc.11.41 Abstract An environmentally friendly Matsuda–Heck reaction with arenediazonium tosylates has been developed

Functionalized branched EDOT-terthiophene copolymer films by electropolymerization and post-polymerization “click”-reactions

• Miriam Goll,
• Adrian Ruff,
• Erna Muks,
• Felix Goerigk,
• Beatrice Omiecienski,
• Ines Ruff,
• Rafael C. González-Cano,
• Juan T. Lopez Navarrete,
• M. Carmen Ruiz Delgado and
• Sabine Ludwigs

Beilstein J. Org. Chem. 2015, 11, 335–347, doi:10.3762/bjoc.11.39

• . Such an orthogonal functionalization may further be used to control the properties in new materials for organic photovoltaics where low oxidation potentials are needed (monomer ratio) and a good processability from environmental solvents (e.g., water) is desired (introduction of polar/ionic groups

Solution processable diketopyrrolopyrrole (DPP) cored small molecules with BODIPY end groups as novel donors for organic solar cells

• Diego Cortizo-Lacalle,
• Calvyn T. Howells,
• Upendra K. Pandey,
• Joseph Cameron,
• Neil J. Findlay,
• Anto Regis Inigo,
• Tell Tuttle,
• Peter J. Skabara and
• Ifor D. W. Samuel

Beilstein J. Org. Chem. 2014, 10, 2683–2695, doi:10.3762/bjoc.10.283

• the tendency for 10 to aggregate to a greater degree than 9. We believe these two DPP cored derivatives to be of interest for photovoltaic applications. Moreover, we are synthesising some new materials which have superior solubility and will not be prone to aggregate on the microscopic scale

Towards the sequence-specific multivalent molecular recognition of cyclodextrin oligomers

• Michael Kurlemann and
• Bart Jan Ravoo

Beilstein J. Org. Chem. 2014, 10, 2428–2440, doi:10.3762/bjoc.10.253

• . Furthermore, sequence-specific recognition motifs have been used in various artificial systems in the last years, e.g., to emulate biological processes or to build up new materials with highly specific recognition domains. In this article, we present the preparation of cyclodextrin (CD)-based strands and

Specific DNA duplex formation at an artificial lipid bilayer: fluorescence microscopy after Sybr Green I staining

• Emma Werz and
• Helmut Rosemeyer

Beilstein J. Org. Chem. 2014, 10, 2307–2321, doi:10.3762/bjoc.10.240

• Emma Werz Helmut Rosemeyer Organic Materials Chemistry and Bioorganic Chemistry, Institute of Chemistry of New Materials, University of Osnabrück, Barbarastr. 7, D-49069 Osnabrück, Germany Ionovation GmbH, Westerbreite 7 (CUT), D-49084 Osnabrück, Germany 10.3762/bjoc.10.240 Abstract The article