Peptide–polymer ligands for a tandem WW-domain, an adaptive multivalent protein–protein interaction: lessons on the thermodynamic fitness of flexible ligands

• Katharina Koschek,
• Vedat Durmaz,
• Oxana Krylova,
• Marek Wieczorek,
• Shilpi Gupta,
• Martin Richter,
• Alexander Bujotzek,
• Christina Fischer,
• Rainer Haag,
• Christian Freund,
• Marcus Weber and
• Jörg Rademann

Beilstein J. Org. Chem. 2015, 11, 837–847, doi:10.3762/bjoc.11.93

• , 14195 Berlin, Germany Department of Medicinal Chemistry, Leibniz Institut für Molekulare Pharmakologie, Robert-Rössle-Str. 10, 13125 Berlin, Germany Fraunhofer Institute for Manufacturing Technology and Advanced Materials (IFAM), Wiener Str. 12, 28359 Bremen, Germany Konrad-Zuse-Zentrum für

Adsorption mechanism and valency of catechol-functionalized hyperbranched polyglycerols

• Stefanie Krysiak,
• Qiang Wei,
• Klaus Rischka,
• Andreas Hartwig,
• Rainer Haag and
• Thorsten Hugel

Beilstein J. Org. Chem. 2015, 11, 828–836, doi:10.3762/bjoc.11.92

• Technology and Advanced Materials (FhG IFAM), 28359 Bremen, Germany Institute of Physical Chemistry, University of Freiburg, Albertstraße 23a, 79104 Freiburg, Germany 10.3762/bjoc.11.92 Abstract Nature often serves as a model system for developing new adhesives. In aqueous environments, mussel-inspired

Highly selective electrochemical fluorination of dithioacetal derivatives bearing electron-withdrawing substituents at the position α to the sulfur atom using poly(HF) salts

• Bin Yin,
• Shinsuke Inagi and
• Toshio Fuchigami

Beilstein J. Org. Chem. 2015, 11, 85–91, doi:10.3762/bjoc.11.12

• = 3–5)] that were used as supporting salt fluorine source. We also thank technical staffs working at Center for Advanced Materials Analysis (Suzukakedai Campus) of Tokyo Institute of Technology for analyzing new compounds. One of the authors (Y. B.) acknowledges Ministry of Education, Culture, Sports

Synthesis and characterization of pH responsive D-glucosamine based molecular gelators

• Navneet Goyal,
• Hari P. R. Mangunuru,
• Bargav Parikh,
• Sonu Shrestha and
• Guijun Wang

Beilstein J. Org. Chem. 2014, 10, 3111–3121, doi:10.3762/bjoc.10.328

• ; naproxen; organogelator; pH responsive; self-assembly; Introduction Low molecular weight gelators (LMWGs) have drawn great attention over the past few decades due to the formation of supramolecular structures and their potential applications as advanced materials [1][2][3][4][5][6][7]. LMWGs are also

Synthesis of graft polyrotaxane by simultaneous capping of backbone and grafting from rings of pseudo-polyrotaxane

• Kazuaki Kato,
• Katsunari Inoue,
• Masabumi Kudo and
• Kohzo Ito

Beilstein J. Org. Chem. 2014, 10, 2573–2579, doi:10.3762/bjoc.10.269

• Kazuaki Kato Katsunari Inoue Masabumi Kudo Kohzo Ito Department of Advanced Materials Science, Graduate School of Frontier Sciences, The University of Tokyo, 5-1-5 Kashiwanoha, Kashiwa, Chiba 277-8561, Japan Advanced Softmaterials Inc., Tokatsu Techno Plaza 403, 5-4-6 Kashiwanoha, Kashiwa, Chiba

A versatile δ-aminolevulinic acid (ΑLA)-cyclodextrin bimodal conjugate-prodrug for PDT applications with the help of intracellular chemistry

• Chrysie Aggelidou,
• Theodossis A. Theodossiou,
• Antonio Ricardo Gonçalves,
• Mariza Lampropoulou and
• Konstantina Yannakopoulou

Beilstein J. Org. Chem. 2014, 10, 2414–2420, doi:10.3762/bjoc.10.251

• Chrysie Aggelidou Theodossis A. Theodossiou Antonio Ricardo Goncalves Mariza Lampropoulou Konstantina Yannakopoulou Institute of Advanced Materials, Physicochemical Processes, Nanotechnology & Microsystems, National Center for Scientific Research “Demokritos”, Patriarchou Gregoriou & Neapoleos

Aryl substitution of pentacenes

• Andreas R. Waterloo,
• Anna-Chiara Sale,
• Dan Lehnherr,
• Frank Hampel and
• Rik R. Tykwinski

Beilstein J. Org. Chem. 2014, 10, 1692–1705, doi:10.3762/bjoc.10.178

• Advanced Materials”. We thank Dr. Michael J. Ferguson for the X-ray crystallographic analysis of ketone 4b.

Staudinger ligation towards cyclodextrin dimers in aqueous/organic media. Synthesis, conformations and guest-encapsulation ability

• Malamatenia D. Manouilidou,
• Yannis G. Lazarou,
• Irene M. Mavridis and
• Konstantina Yannakopoulou

Beilstein J. Org. Chem. 2014, 10, 774–783, doi:10.3762/bjoc.10.73

• Malamatenia D. Manouilidou Yannis G. Lazarou Irene M. Mavridis Konstantina Yannakopoulou Institute of Advanced Materials, Physicochemical Processes, Nanotechnology & Microsystems, National Center for Scientific Research “Demokritos”, Terma Patriarchou Gregoriou & Neapoleos, Aghia Paraskevi Attikis

Synthesis of axially chiral gold complexes and their applications in asymmetric catalyses

• Yin-wei Sun,
• Qin Xu and
• Min Shi

Beilstein J. Org. Chem. 2013, 9, 2224–2232, doi:10.3762/bjoc.9.261

• Yin-wei Sun Qin Xu Min Shi Key Laboratory for Advanced Materials and Institute of Fine Chemicals, School of Chemistry & Molecular Engineering, East China University of Science and Technology, and 130 MeiLong Road, Shanghai 200237, People’s Republic of China, State Key Laboratory of Organometallic

Gold-catalyzed reaction of oxabicyclic alkenes with electron-deficient terminal alkynes to produce acrylate derivatives

• Yin-wei Sun,
• Qin Xu and
• Min Shi

Beilstein J. Org. Chem. 2013, 9, 1969–1976, doi:10.3762/bjoc.9.233

• Yin-wei Sun Qin Xu Min Shi Key Laboratory for Advanced Materials and Institute of Fine Chemicals, School of Chemistry & Molecular Engineering, East China University of Science and Technology, 130 MeiLong Road, Shanghai 200237, People’s Republic of China, State Key Laboratory of Organometallic

Synthesis, photophysical and electrochemical characterization of terpyridine-functionalized dendritic oligothiophenes and their Ru(II) complexes

• Amaresh Mishra,
• Elena Mena-Osteritz and
• Peter Bäuerle

Beilstein J. Org. Chem. 2013, 9, 866–876, doi:10.3762/bjoc.9.100

• Amaresh Mishra Elena Mena-Osteritz Peter Bauerle Institute of Organic Chemistry II and Advanced Materials, Ulm University, Albert-Einstein-Allee 11, 89081 Ulm, Germany 10.3762/bjoc.9.100 Abstract Pd-catalyzed Sonogashira cross-coupling reactions were used to synthesize novel π-conjugated

Gold-catalyzed oxycyclization of allenic carbamates: expeditious synthesis of 1,3-oxazin-2-ones

• Benito Alcaide,
• Pedro Almendros,
• M. Teresa Quirós and
• Israel Fernández

Beilstein J. Org. Chem. 2013, 9, 818–826, doi:10.3762/bjoc.9.93

• are also used as valuable intermediates in organic synthesis [8][9][10][11][12][13][14]. Recently, allenes have attracted much attention as they have been used for the preparation of both biologically relevant drugs as well as advanced materials [15][16][17][18][19][20][21][22][23][24][25][26][27

Chiral multifunctional thiourea-phosphine catalyzed asymmetric [3 + 2] annulation of Morita–Baylis–Hillman carbonates with maleimides

• Hong-Ping Deng,
• De Wang,
• Yin Wei and
• Min Shi

Beilstein J. Org. Chem. 2012, 8, 1098–1104, doi:10.3762/bjoc.8.121

• Hong-Ping Deng De Wang Yin Wei Min Shi State Key Laboratory of Organometallic Chemistry, Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences, 354 Fenglin Road, Shanghai 200032, People’s Republic of China Key Laboratory for Advanced Materials and Institute of Fine Chemicals, School

Molecular switches and cages

• Dirk Trauner

Beilstein J. Org. Chem. 2012, 8, 870–871, doi:10.3762/bjoc.8.97

• complex systems to respond to changes in their environment defined by light intensity, pH, temperature or voltage. As such, molecular switches play a key role in biology and information technology and have become important components of advanced materials. Chemists have developed a large number of

• , optically active macrocycles (Pasini). Molecular switches that respond to changes in pH are covered as well (Haberhauer and Aprahamian), reflecting their importance in biology and in materials science. Finally, switching is highlighted as a synthetic strategy for building advanced materials that are useful

Synthesis of axially chiral oxazoline–carbene ligands with an N-naphthyl framework and a study of their coordination with AuCl·SMe₂

• Feijun Wang,
• Shengke Li,
• Mingliang Qu,
• Mei-Xin Zhao,
• Lian-Jun Liu and
• Min Shi

Beilstein J. Org. Chem. 2012, 8, 726–731, doi:10.3762/bjoc.8.81

• Feijun Wang Shengke Li Mingliang Qu Mei-Xin Zhao Lian-Jun Liu Min Shi Key Laboratory for Advanced Materials and Institute of Fine Chemicals, East China University of Science and Technology, 130 MeiLong Road, Shanghai 200237, P. R. China State Key Laboratory of Organometallic Chemistry, Shanghai

Thiophene-based donor–acceptor co-oligomers by copper-catalyzed 1,3-dipolar cycloaddition

• Stefanie Potratz,
• Amaresh Mishra and
• Peter Bäuerle

Beilstein J. Org. Chem. 2012, 8, 683–692, doi:10.3762/bjoc.8.76

• Stefanie Potratz Amaresh Mishra Peter Bauerle University of Ulm, Institute of Organic Chemistry II and Advanced Materials, Albert-Einstein-Allee 11, 89081 Ulm, Germany 10.3762/bjoc.8.76 Abstract Herein we present a three-component one-pot procedure to synthesize co-oligomers of a donor–acceptor

Perhydroazulene-based liquid-crystalline materials with smectic phases

• Zakir Hussain,
• Henning Hopf and
• S. Holger Eichhorn

Beilstein J. Org. Chem. 2012, 8, 403–410, doi:10.3762/bjoc.8.44

• properties of calamitic liquid crystals [3][4][5][6][7][8]. However, there is still a growing need for more advanced materials to be synthesized and tested for the desired features of the displays. Moreover, the properties of the LC materials required for applications in LCDs are achieved by mixture

Synthesis and mesomorphic properties of calamitic malonates and cyanoacetates tethered to 4-cyanobiphenyls

• Katharina C. Kress,
• Martin Kaller,
• Kirill V. Axenov,
• Stefan Tussetschläger and
• Sabine Laschat

Beilstein J. Org. Chem. 2012, 8, 371–378, doi:10.3762/bjoc.8.40

• Forschung, the Ministerium für Wissenschaft, Forschung und Kunst des Landes Baden-Württemberg and the Max-Planck-Gesellschaft (International Max Planck Research School for Advanced Materials fellowship for M.K.) is gratefully acknowledged. We would like to thank Ingo Dierking for helpful discussions and

Liquid-crystalline nanoparticles: Hybrid design and mesophase structures

• Gareth L. Nealon,
• Romain Greget,
• Cristina Dominguez,
• Zsuzsanna T. Nagy,
• Daniel Guillon,
• Jean-Louis Gallani and
• Bertrand Donnio

Beilstein J. Org. Chem. 2012, 8, 349–370, doi:10.3762/bjoc.8.39

• factors, such as applied magnetic and electric fields and surface effects, all of which lend these materials towards their use in stimuli-responsive advanced materials [24]. What follows is a brief introduction to some of the salient points in LC science, but a thorough introduction to the theory and

Recent advances in the gold-catalyzed additions to C–C multiple bonds

• He Huang,
• Yu Zhou and
• Hong Liu

Beilstein J. Org. Chem. 2011, 7, 897–936, doi:10.3762/bjoc.7.103

• compounds, ranging from pharmaceuticals and agrochemicals to advanced materials and polymers. Cationic gold acts as a soft and carbophilic Lewis acid and is considered one of the most powerful activators of C–C multiple bonds. Consequently, gold-catalysis plays an important role in the development of new

Isotopic labelling studies for a gold-catalysed skeletal rearrangement of alkynyl aziridines

• Paul W. Davies,
• Nicolas Martin and
• Neil Spencer

Beilstein J. Org. Chem. 2011, 7, 839–846, doi:10.3762/bjoc.7.96

• Birmingham Science City: Innovative Uses for Advanced Materials in the Modern World (West Midlands Centre for Advanced Materials Project 2), with support from Advantage West Midlands (AWM) and partly funded by the European Regional Development Fund (ERDF). We thank Johnson Matthey plc for a generous loan of

Synthesis of chiral mono(N-heterocyclic carbene) palladium and gold complexes with a 1,1'-biphenyl scaffold and their applications in catalysis

• Lian-jun Liu,
• Feijun Wang,
• Wenfeng Wang,
• Mei-xin Zhao and
• Min Shi

Beilstein J. Org. Chem. 2011, 7, 555–564, doi:10.3762/bjoc.7.64

• Lian-jun Liu Feijun Wang Wenfeng Wang Mei-xin Zhao Min Shi Key Laboratory for Advanced Materials and Institute of Fine Chemicals, School of Chemistry & Molecular Engineering, East China University of Science and Technology, 130 MeiLong Road, Shanghai 200237, People’s Republic of China State Key

Studies on Pd/NiFe₂O₄ catalyzed ligand-free Suzuki reaction in aqueous phase: synthesis of biaryls, terphenyls and polyaryls

• Sanjay R. Borhade and
• Suresh B. Waghmode

Beilstein J. Org. Chem. 2011, 7, 310–319, doi:10.3762/bjoc.7.41

• products, pharmaceutical intermediates, pesticides, advanced materials and liquid crystals [8][9][10]. These applications, in turn, have led to the production of biaryls and polyaryls on the industrial scale [11]. The Suzuki reaction is usually performed with homogeneous palladium catalysts in the presence

Towards racemizable chiral organogelators

• Jian Bin Lin,
• Debarshi Dasgupta,
• Seda Cantekin and
• Albertus P. H. J. Schenning

Beilstein J. Org. Chem. 2010, 6, 960–965, doi:10.3762/bjoc.6.107

• advanced materials and constrained media for chiral synthesis and separation [3][4][5]. The development of systems where the chiral supramolecular assembly responds to specific triggers, should facilitate the design of smart functional materials in which subtle molecular-scale changes have an impact on the

Suzuki–Miyaura cross-coupling reaction of 1-aryltriazenes with arylboronic acids catalyzed by a recyclable polymer-supported N-heterocyclic carbene–palladium complex catalyst

• Guangming Nan,
• Fang Ren and
• Meiming Luo

Beilstein J. Org. Chem. 2010, 6, No. 70, doi:10.3762/bjoc.6.70

• ; recyclable catalyst; Suzuki–Miyaura reaction; Introduction The unsymmetrical biaryls feature in a diverse range of organic compounds, such as natural products, advanced materials, liquid crystals, ligands and molecules of medicinal interest [1][2][3][4]. The palladium-catalyzed Suzuki–Miyaura cross-coupling