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Search for "supramolecular chemistry" in Full Text gives 212 result(s) in Beilstein Journal of Organic Chemistry. Showing first 200.

Self and directed assembly: people and molecules

  • Tony D. James

Beilstein J. Org. Chem. 2016, 12, 391–405, doi:10.3762/bjoc.12.42

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  • Tony D. James Department of Chemistry, University of Bath, Bath, BA2 7AY UK 10.3762/bjoc.12.42 Abstract Self-assembly and directed-assembly are two very important aspects of supramolecular chemistry. As a young postgraduate student working in Canada with Tom Fyles my introduction to
  • Supramolecular Chemistry was through the self-assembly of phospholipid membranes to form vesicles for which we were developing unimolecular and self-assembling transporter molecules. The next stage of my development as a scientist was in Japan with Seiji Shinkai where in a “Eureka” moment, the boronic acid
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Published 01 Mar 2016

Art, auto-mechanics, and supramolecular chemistry. A merging of hobbies and career

  • Eric V. Anslyn

Beilstein J. Org. Chem. 2016, 12, 362–376, doi:10.3762/bjoc.12.40

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  • Eric V. Anslyn Department of Chemistry, University of Texas, Austin, TX 78712, USA 10.3762/bjoc.12.40 Abstract While the strict definition of supramolecular chemistry is “chemistry beyond the molecule”, meaning having a focus on non-covalent interactions, the field is primarily associated with
  • draw for me to the fields of supramolecular chemistry and molecular orbital theory, because I grew up in a household filled with art. In addition to art, my childhood was filled with repairing and constructing mechanical entities, such as internal combustion motors, where many components work together
  • to achieve a function. Analogously, the field of supramolecular chemistry creates systems of high complexity that achieve functions or perform tasks. Therefore, in retrospect a career in supramolecular chemistry appears to be simply an extension of childhood hobbies involving art and auto-mechanics
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Published 26 Feb 2016

My maize and blue brick road to physical organic chemistry in materials

  • Anne J. McNeil

Beilstein J. Org. Chem. 2016, 12, 229–238, doi:10.3762/bjoc.12.24

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  • field of supramolecular chemistry, specifically, and organic materials, broadly. My research group’s efforts toward designing new sensors based on small molecule gelators are described. In particular, I highlight how our design strategy has evolved as we learn more about molecular gelators. This
  • perspective concludes with some predictions about where molecular gels, as well as my personal and professional life, are headed. Keywords: molecular gel; organic chemistry; organic materials; self-assembly; supramolecular chemistry; Review One of my earliest memories involves pouring water down our
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Published 08 Feb 2016

A journey in bioinspired supramolecular chemistry: from molecular tweezers to small molecules that target myotonic dystrophy

  • Steven C. Zimmerman

Beilstein J. Org. Chem. 2016, 12, 125–138, doi:10.3762/bjoc.12.14

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  • Steven C. Zimmerman Department of Chemistry, University of Illinois at Urbana-Champaign, Urbana, Illinois 61801, United States 10.3762/bjoc.12.14 Abstract This review summarizes part of the author’s research in the area of supramolecular chemistry, beginning with his early life influences and
  • therapeutic agents for myotonic dystrophy using a rational design approach that heavily relies on principles of supramolecular chemistry. How this work was influenced by that of others in the field and the evolution of each area of research is highlighted with selected examples. Keywords: catenanes
  • from research and teaching, the department head job was interesting, challenging, and highly rewarding in seeing the department move forward, especially with the help of our loyal alumni. We entitled the thematic issue containing this contribution “Supramolecular chemistry at the interface of biology
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Published 25 Jan 2016

Supramolecular polymer assembly in aqueous solution arising from cyclodextrin host–guest complexation

  • Jie Wang,
  • Zhiqiang Qiu,
  • Yiming Wang,
  • Li Li,
  • Xuhong Guo,
  • Duc-Truc Pham,
  • Stephen F. Lincoln and
  • Robert K. Prud’homme

Beilstein J. Org. Chem. 2016, 12, 50–72, doi:10.3762/bjoc.12.7

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  • [112][113][114]. Conclusion and Perspective In this brief review it is shown that there is a plethora of routes to supramolecular polymer networks in aqueous solution based on cyclodextrin host–guest complexation. Through variations in this supramolecular chemistry at the molecular level macroscopic
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Published 12 Jan 2016

Bright molecules for sensing, computing and imaging: a tale of two once-troubled cities

  • A. Prasanna de Silva

Beilstein J. Org. Chem. 2015, 11, 2774–2784, doi:10.3762/bjoc.11.298

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  • remember. I was fortunate to be introduced to an Irish traditional band 17 years ago and we have kept on playing since then. Epilogue Since supramolecular chemistry concerns molecule–molecule interactions, its principles can be adapted to miniaturize people–people interactions or people–object interactions
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Published 29 Dec 2015

Learning from the unexpected in life and DNA self-assembly

  • Jennifer M. Heemstra

Beilstein J. Org. Chem. 2015, 11, 2713–2720, doi:10.3762/bjoc.11.292

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  • science and began to pave the road to my future career in chemistry. At every step along this road, I benefited from fantastic mentors who shared with me their enthusiasm for life and learning. I also grew to recognize my love of supramolecular chemistry, and this has been the constant theme driving my
  • interesting to experience research in a chemistry lab. I read through all of the faculty research descriptions, and while I was still years away from recognizing an underlying love of supramolecular chemistry, I was immediately drawn to the work of Prof. James Nowick, whose lab was focused on constructing and
  • choosing a graduate program, I had learned the phrase “supramolecular chemistry” and recognized my excitement for the process of designing, building, and studying functional molecular architectures. In the process of researching graduate programs, I read a series of papers from the lab of Prof. Jeff Moore
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Published 23 Dec 2015

Synthesis and photophysical characteristics of polyfluorene polyrotaxanes

  • Aurica Farcas,
  • Giulia Tregnago,
  • Ana-Maria Resmerita,
  • Pierre-Henri Aubert and
  • Franco Cacialli

Beilstein J. Org. Chem. 2015, 11, 2677–2688, doi:10.3762/bjoc.11.288

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  • Aurica Farcas Giulia Tregnago Ana-Maria Resmerita Pierre-Henri Aubert Franco Cacialli Supramolecular Chemistry Group, ‘‘Petru Poni’’ Institute of Macromolecular Chemistry, Grigore Ghica Voda Alley, 700487-Iasi, Romania London Centre for Nanotechnology and Department of Physics and Astronomy
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Published 21 Dec 2015

Assembly of synthetic Aβ miniamyloids on polyol templates

  • Sebastian Nils Fischer and
  • Armin Geyer

Beilstein J. Org. Chem. 2015, 11, 2646–2653, doi:10.3762/bjoc.11.284

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  • the supramolecular chemistry of Aβ with the concepts of reversible covalent chemistry. The present study shows how oligomers of the Hot=Tap dipeptide serve as templates for the reversible covalent esterification of boronic acids which mediate the assembly of monodisperse Aβ miniamyloids. The modular
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Published 17 Dec 2015

Inclusion complexes of 2-methoxyestradiol with dimethylated and permethylated β-cyclodextrins: models for cyclodextrin–steroid interaction

  • Mino R. Caira,
  • Susan A. Bourne,
  • Halima Samsodien and
  • Vincent J. Smith

Beilstein J. Org. Chem. 2015, 11, 2616–2630, doi:10.3762/bjoc.11.281

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  • Mino R. Caira Susan A. Bourne Halima Samsodien Vincent J. Smith Centre for Supramolecular Chemistry Research (CSCR), Department of Chemistry, University of Cape Town, Rondebosch 7701, South Africa 10.3762/bjoc.11.281 Abstract The interaction between the potent anticancer agent 2-methoxyestradiol
  • File 430: Additional data. Acknowledgements Members of the Centre for Supramolecular Chemistry Research who were involved in the study reported here express their thanks to the National Research Foundation (Pretoria) and the University of Cape Town for research support. Any opinion, findings and
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Published 16 Dec 2015

Synthesis of bi- and bis-1,2,3-triazoles by copper-catalyzed Huisgen cycloaddition: A family of valuable products by click chemistry

  • Zhan-Jiang Zheng,
  • Ding Wang,
  • Zheng Xu and
  • Li-Wen Xu

Beilstein J. Org. Chem. 2015, 11, 2557–2576, doi:10.3762/bjoc.11.276

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  • addition, the application of bitriazoles and the related CuAAAC reaction in different fields, including medicinal chemistry, coordination chemistry, biochemistry, and supramolecular chemistry, have been highlighted. Keywords: bistriazoles; click chemistry; cycloaddition; homogeneous catalysis; oxidative
  • dialkyne spacers In the past years, bistriazoles with dialkyne spacers have gained significant attention for their potential application in supramolecular chemistry, pharmaceutical chemistry, biological chemistry and organometallic chemistry. The construction of bistriazoles from dialkynes is now well
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Published 11 Dec 2015

Smart molecules for imaging, sensing and health (SMITH)

  • Bradley D. Smith

Beilstein J. Org. Chem. 2015, 11, 2540–2548, doi:10.3762/bjoc.11.274

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  • Bradley D. Smith University of Notre Dame, Notre Dame, IN 46530, USA 10.3762/bjoc.11.274 Abstract This autobiographical review provides a personal account of the author’s academic journey in supramolecular chemistry, including brief summaries of research efforts in membrane transport, molecular
  • imaging, ion-pair receptors, rotaxane synthesis, squaraine rotaxanes, and synthtavidin technology. The article concludes with a short perspective of likely future directions in biomedical supramolecular chemistry. Keywords: fluorescence; ion-pair receptors; membrane transport; molecular imaging; rotaxane
  • considered supramolecular chemistry. So it was a little risky to start an independent academic career in a field with no previous experience. Indeed my new lab had to start from the beginning and learn all the rudimentary supramolecular experimental techniques such as measuring binding constants and
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Published 10 Dec 2015

Size-controlled and redox-responsive supramolecular nanoparticles

  • Raquel Mejia-Ariza,
  • Gavin A. Kronig and
  • Jurriaan Huskens

Beilstein J. Org. Chem. 2015, 11, 2388–2399, doi:10.3762/bjoc.11.260

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  • core of the SNPs. Keywords: host–guest interactions; nanoparticles; self-assembly; stimulus-responsive; supramolecular chemistry; Introduction Self-assembly and molecular recognition are two core concepts underlying supramolecular chemistry. These offer convenient and versatile pathways to
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Published 01 Dec 2015

Conformational equilibrium in supramolecular chemistry: Dibutyltriuret case

  • Karina Mroczyńska,
  • Małgorzata Kaczorowska,
  • Erkki Kolehmainen,
  • Ireneusz Grubecki,
  • Marek Pietrzak and
  • Borys Ośmiałowski

Beilstein J. Org. Chem. 2015, 11, 2105–2116, doi:10.3762/bjoc.11.227

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  • ; hydrogen bonding; NMR; rotamerism; supramolecular chemistry; Introduction The hydrogen bond (HB) is one of the most common non-covalent interactions. Since it stabilizes, for example, the double helix of DNA and influences peptide folding it is quite reasonable to assume that HBing is crucial for
  • observations are in line with computations that are very useful in drawing conclusions. The use of benzoates with regularly changed properties may be the method of choice in analysis of complexes. The pre-organization of molecules used in supramolecular chemistry is, in general, important to this field. On the
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Published 05 Nov 2015

Supramolecular chemistry: from aromatic foldamers to solution-phase supramolecular organic frameworks

  • Zhan-Ting Li

Beilstein J. Org. Chem. 2015, 11, 2057–2071, doi:10.3762/bjoc.11.222

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  • sulfur-containing molecules and since the early 1990s, tetrathiafulvalene (TTF) supramolecular chemistry. Before I went to Odense, the group had developed a very useful method of in situ generation of TTF thiolate anion from cyanoethylated precursors, which greatly simplifies the modification of the TTF
  • organic solvents. With hexafluorophosphate as the counterion, the catenanes were well-dissolved in acetonitrile, while with chloride, their solubility was poor. My stay in Odense initiated my research in supramolecular chemistry. For many years, I maintained interest in interlocked systems. TTF is also a
  • the hydrogen-bonded aromatic amide and hydrazide sequences as a longstanding research area. With these sequences as a structural basis, we were able to investigate many interesting phenomena or concepts in supramolecular chemistry such as stimuli responsiveness, “sergeant–soldier effect”, and
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Published 02 Nov 2015

The simple production of nonsymmetric quaterpyridines through Kröhnke pyridine synthesis

  • Isabelle Sasaki,
  • Jean-Claude Daran and
  • Gérard Commenges

Beilstein J. Org. Chem. 2015, 11, 1781–1785, doi:10.3762/bjoc.11.193

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  • building blocks in metallo-supramolecular chemistry; however, their synthesis requires the preparation of sensitive building blocks. We present here three examples of nonsymmetric quaterpyridines that were easily obtained in yields of 70–85% by condensation of commercially available enones with 6-acetyl
  • pyridine synthesis; Mannich bases; platinum; X-ray diffraction; Findings Polypyridines have been demonstrated to be useful building blocks in metallo-supramolecular chemistry [1][2][3]. In particular, polypyridines joined at the 2,6-position have the ability to accommodate different coordination numbers
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Published 30 Sep 2015

Star-shaped tetrathiafulvalene oligomers towards the construction of conducting supramolecular assembly

  • Masahiko Iyoda and
  • Masashi Hasegawa

Beilstein J. Org. Chem. 2015, 11, 1596–1613, doi:10.3762/bjoc.11.175

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  • -controlled gelation processes. TTF-based supramolecular chemistry in solution was thoroughly outlined in recent reviews of Jeppesen, Nielsen, and Becher (2004) [24], Iyoda, Hasegawa, and Miyake (2004) [25][26], Sallé and Zhang (2009) [27], and Martin (2009, 2012) [28][29]. However, limited examples of redox
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Published 10 Sep 2015

Qualitative evaluation of regioselectivity in the formation of di- and tri-6-O-tritylates of α-cyclodextrin

  • Keisuke Yoshikiyo,
  • Yoshihisa Matsui and
  • Tatsuyuki Yamamoto

Beilstein J. Org. Chem. 2015, 11, 1530–1540, doi:10.3762/bjoc.11.168

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  • supramolecular chemistry, as they allow the preparation of sophisticated concave molecules such as multi- or hetero-functionalized CD derivatives that are important intermediates for the preparation of enzyme mimics [1][2][3][4][5]. The tritylation of cyclodextrin (CD) has attracted much attention, since the
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Published 02 Sep 2015

Tetrathiafulvalene-based azine ligands for anion and metal cation coordination

  • Awatef Ayadi,
  • Aziz El Alamy,
  • Olivier Alévêque,
  • Magali Allain,
  • Nabil Zouari,
  • Mohammed Bouachrine and
  • Abdelkrim El-Ghayoury

Beilstein J. Org. Chem. 2015, 11, 1379–1391, doi:10.3762/bjoc.11.149

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  • -responsive receptors for neutral and/or charged guest sensing applications have been prepared [18][19][20][21][22]. On this ground, chemosensors capable of recognizing anionic and/or cationic species constitute an important area of increasing research in supramolecular chemistry, considering the ubiquitous
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Published 07 Aug 2015

Selected synthetic strategies to cyclophanes

  • Sambasivarao Kotha,
  • Mukesh E. Shirbhate and
  • Gopalkrushna T. Waghule

Beilstein J. Org. Chem. 2015, 11, 1274–1331, doi:10.3762/bjoc.11.142

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  • many biologically active natural products such as macrocidin A (19) and B (20) [64], nostocyclyne A (21) [65], and in the turriane family of natural products 22–24 [66]. Cyclophanes are also applied in research areas such as pharmaceuticals [67][68], catalysis [69][70] and supramolecular chemistry [71
  • attention of synthetic chemists. Liu and co-workers [166] have constructed the [10]paracyclophane 208 (skeleton of hirsutellones) via RCM. The 2,2’-bipyridine unit is an interesting building block due to its use in chelating ligands, as a binding agent and also a useful template in supramolecular chemistry
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Published 29 Jul 2015

Advances in the synthesis of functionalised pyrrolotetrathiafulvalenes

  • Luke J. O’Driscoll,
  • Sissel S. Andersen,
  • Marta V. Solano,
  • Dan Bendixen,
  • Morten Jensen,
  • Troels Duedal,
  • Jess Lycoops,
  • Cornelia van der Pol,
  • Rebecca E. Sørensen,
  • Karina R. Larsen,
  • Kenneth Myntman,
  • Christian Henriksen,
  • Stinne W. Hansen and
  • Jan O. Jeppesen

Beilstein J. Org. Chem. 2015, 11, 1112–1122, doi:10.3762/bjoc.11.125

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  • bispyrrolotetrathiafulvalenes (BPTTFs, 5) are useful structural motifs and have found widespread use in fields such as supramolecular chemistry and molecular electronics. Protocols enabling the synthesis of functionalised MPTTFs and BPTTFs are therefore of broad interest. Herein, we present the synthesis of a range of
  • to the N-arylation of MPTTFs and BPTTFs using a variety of aryl halides. Keywords: heterocycles; protecting groups; sulfur chemistry; tetrathiafulvalene; Ullman coupling; Introduction Tetrathiafulvalene (TTF) derivatives are of considerable interest in the fields of supramolecular chemistry and
  • materials with applications in supramolecular chemistry, molecular electronics and as sensors. The sequential, reversible oxidation of TTF (1) to its stable radical cation (2) and dication (3) states. Structures and possible substitution positions of MPTTFs (4) and BPTTFs (5). Large-scale synthesis of 6
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Published 03 Jul 2015

Glycoluril–tetrathiafulvalene molecular clips: on the influence of electronic and spatial properties for binding neutral accepting guests

  • Yoann Cotelle,
  • Marie Hardouin-Lerouge,
  • Stéphanie Legoupy,
  • Olivier Alévêque,
  • Eric Levillain and
  • Piétrick Hudhomme

Beilstein J. Org. Chem. 2015, 11, 1023–1036, doi:10.3762/bjoc.11.115

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  • control binding interaction towards a strong electron acceptor such as tetrafluorotetracyanoquinodimethane (F4-TCNQ) or a weaker electron acceptor such as 1,3-dinitrobenzene (m-DNB). Keywords: donor–acceptor interactions; glycoluril; molecular clips; supramolecular chemistry; tetrathiafulvalene
  • -known access to molecular conductors [6][7] and TTF-acceptor assemblies [8][9], new concepts have been explored in the field of supramolecular chemistry using the TTF unit as a powerful electroactive building block [10]. Exploiting its peculiar electronic (two successive reversible oxidation steps
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Published 17 Jun 2015

Multivalency as a chemical organization and action principle

  • Rainer Haag

Beilstein J. Org. Chem. 2015, 11, 848–849, doi:10.3762/bjoc.11.94

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  • Rainer Haag Institute for Chemistry and Biochemistry, Freie Universität Berlin, Takustr. 3, 14195 Berlin, Germany 10.3762/bjoc.11.94 Keywords: glycoarchitectures; supramolecular chemistry; multivalency; multivalent protein inhibitors; pathogen binding; Multivalency is a key principle in nature
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Published 19 May 2015

Mechanical stability of bivalent transition metal complexes analyzed by single-molecule force spectroscopy

  • Manuel Gensler,
  • Christian Eidamshaus,
  • Maurice Taszarek,
  • Hans-Ulrich Reissig and
  • Jürgen P. Rabe

Beilstein J. Org. Chem. 2015, 11, 817–827, doi:10.3762/bjoc.11.91

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  • important in biochemistry [1] and supramolecular chemistry [2], but still not fully understood on the level of individual non-covalent interactions [3]. Synthetic supramolecular systems are ideal for a quantitative analysis of multivalency on the level of single molecules, because specific ligand design can
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Published 15 May 2015

Discrete multiporphyrin pseudorotaxane assemblies from di- and tetravalent porphyrin building blocks

  • Mirko Lohse,
  • Larissa K. S. von Krbek,
  • Sebastian Radunz,
  • Suresh Moorthy,
  • Christoph A. Schalley and
  • Stefan Hecht

Beilstein J. Org. Chem. 2015, 11, 748–762, doi:10.3762/bjoc.11.85

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  • ; pseudorotaxanes; Introduction Supramolecular chemistry [1], the chemistry “beyond the molecule“ [2], has immensely reshaped the concepts of chemistry by putting the intermolecular interaction into the focus. Different fields of chemistry, from materials [3][4][5][6] and analytical sciences [7][8][9][10][11][12
  • being a mere spacer and scaffold connecting the binding sites, porphyrins also offer interesting physical and optical properties [51][52]. Therefore, they have played a pivotal role in supramolecular chemistry [53][54][55][56][57][58][59][60][61][62][63][64][65][66], for example as potential candidates
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Published 12 May 2015
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