This thematic issue is dedicated to the 5th International Symposium on Synthesis and Catalysis (ISySyCat 2023). Submission is open to all participants of the meeting and their co-authors.

The focus is on current themes of chemical synthesis and catalysis, for example, total synthesis and synthesis in medicinal chemistry, chemical biology, and materials science. Topics covered are new reagents, catalysts, strategies and concepts for organic synthesis, biocatalysis, organocatalysis, flow chemistry, process development towards the synthesis of key pharmaceutical targets, applications of organometallic compounds in synthesis and catalysis, stereoselective synthesis, synthesis and properties of functional molecules and organic materials, sustainable and green synthetic and catalytic methods, computational tools for synthesis and catalysis, and polymer synthesis.