Natural nanofibers embedded in the seed mucilage envelope: composite hydrogels with specific adhesive and frictional properties

• Agnieszka Kreitschitz and
• Stanislav N. Gorb

Beilstein J. Nanotechnol. 2024, 15, 1603–1618, doi:10.3762/bjnano.15.126

• GmbH & Co. KG, Bühl, Germany). The maximal adhesion (Fmax) of the mucilage ranged from 2.03 to 6.22 N [29]. We also tested adhesion of Plantago ovata husk (a seed coat covering the seed, built of mucilaginous cells), which reached 37.4 N; the corresponding control samples of UHU glue reached 30.4 N [29

Liver-targeting iron oxide nanoparticles and their complexes with plant extracts for biocompatibility

• Shushanik A. Kazaryan,
• Seda A. Oganian,
• Gayane S. Vardanyan,
• Anatolie S. Sidorenko and
• Ashkhen A. Hovhannisyan

Beilstein J. Nanotechnol. 2024, 15, 1593–1602, doi:10.3762/bjnano.15.125

• each group, see Experimental section, “Animal experiment model”). However, co-administration of T. polium extract and Fe3O4 NPs (group III), as well as of rutin and Fe3O4 NPs (group IV), resulted in increased ALT activity relative to normal values (up to 10.6 ± 0.7 U/L) by 2.1 and 3.3 times

• of the NPs, their dose, and the application [18]. Thus, based on ALT/AST activity values, it can be concluded that Fe3O4 NPs do not exhibit pronounced toxic effects on the livers of healthy Wistar rats; however, when co-administered with 70% ethanol extract of T. polium and rutin, changes occur in

Ultrablack color in velvet ant cuticle

• Vinicius Marques Lopez,
• Wencke Krings,
• Juliana Reis Machado,
• Stanislav Gorb and
• Rhainer Guillermo-Ferreira

Beilstein J. Nanotechnol. 2024, 15, 1554–1565, doi:10.3762/bjnano.15.122

• purity, water-free, Carl Roth GmbH & Co. KG, Karlsruhe, Germany) and covered with a glass slip. Following the method described in [10], we documented the samples using a Zeiss LSM 700 confocal laser scanning microscope (Carl Zeiss Microscopy GmbH, Jena, Germany). Four stable solid-state lasers emitting

The round-robin approach applied to nanoinformatics: consensus prediction of nanomaterials zeta potential

• Dimitra-Danai Varsou,
• Arkaprava Banerjee,
• Joyita Roy,
• Kunal Roy,
• Giannis Savvas,
• Haralambos Sarimveis,
• Ewelina Wyrzykowska,
• Mateusz Balicki,
• Tomasz Puzyn,
• Georgia Melagraki,
• Iseult Lynch and
• Antreas Afantitis

Beilstein J. Nanotechnol. 2024, 15, 1536–1553, doi:10.3762/bjnano.15.121

• sought that nanoinformatics models comply with a set of predefined criteria, often supplemented by statistical methods recommended by the Organisation for Economic Co-operation and Development (OECD) [22] and the European Chemicals Agency (ECHA) [23]. In addition, there is a growing effort from various

Integrating high-performance computing, machine learning, data management workflows, and infrastructures for multiscale simulations and nanomaterials technologies

• Fabio Le Piane,
• Mario Vozza,
• Matteo Baldoni and
• Francesco Mercuri

Beilstein J. Nanotechnol. 2024, 15, 1498–1521, doi:10.3762/bjnano.15.119

Polymer lipid hybrid nanoparticles for phytochemical delivery: challenges, progress, and future prospects

• Iqra Rahat,
• Pooja Yadav,
• Aditi Singhal,
• Mohammad Fareed,
• Jaganathan Raja Purushothaman,
• Mohammed Aslam,
• Raju Balaji,
• Sonali Patil-Shinde and
• Md. Rizwanullah

Beilstein J. Nanotechnol. 2024, 15, 1473–1497, doi:10.3762/bjnano.15.118

• polyethylene glycol (PEG), poly(lactic-co-glycolic acid) (PLGA), polycaprolactone (PCL), and chitosan (CHS), provides structural integrity, controlled release properties, and protection against premature degradation [14][15]. This hybrid structure improves the encapsulation efficiency of phytochemicals/drugs

• therapeutic effectiveness [17][18]. Additionally, PLHNPs possess the capability to encapsulate and co-deliver two drugs with distinct physicochemical characteristics to a targeted site and show synergistic therapeutic efficacy. In PLHNPs, the lipophilic drugs are encapsulated within the polymeric core, while

• in cancer therapy. This targeted delivery can increase the therapeutic efficacy of drugs while reducing side effects by minimizing off-target effects [61][62]. For instance, Garg et al. fabricated fucose ligand-decorated PLHNPs for the co-delivery of methotrexate and aceclofenac to achieve targeted

Effect of radiation-induced vacancy saturation on the first-order phase transformation in nanoparticles: insights from a model

• Aram Shirinyan and
• Yuriy Bilogorodskyy

Beilstein J. Nanotechnol. 2024, 15, 1453–1472, doi:10.3762/bjnano.15.117

• , respectively. (As we know, most elements of the periodic table are metals.) Among the metals undergoing polymorphic transformations are Fe, Co, V, W, Ti, Tl, Zr, Sr, Mn, Al, Ga, Sc, Ba, Li, Na, and K. Therefore, it is important to examine a comprehensive range of quantities, including thermodynamic parameters

Ion-induced surface reactions and deposition from Pt(CO)₂Cl₂ and Pt(CO)₂Br₂

• Mohammed K. Abdel-Rahman,
• Patrick M. Eckhert,
• Atul Chaudhary,
• Johnathon M. Johnson,
• Jo-Chi Yu,
• Lisa McElwee-White and
• D. Howard Fairbrother

Beilstein J. Nanotechnol. 2024, 15, 1427–1439, doi:10.3762/bjnano.15.115

• 10.3762/bjnano.15.115 Abstract Ion beam-induced deposition (IBID) using Pt(CO)2Cl2 and Pt(CO)2Br2 as precursors has been studied with ultrahigh-vacuum (UHV) surface science techniques to provide insights into the elementary reaction steps involved in deposition, complemented by analysis of deposits formed

• under steady-state conditions. X-ray photoelectron spectroscopy (XPS) and mass spectrometry data from monolayer thick films of Pt(CO)2Cl2 and Pt(CO)2Br2 exposed to 3 keV Ar+, He+, and H2+ ions indicate that deposition is initiated by the desorption of both CO ligands, a process ascribed to momentum

• elementary reaction steps is invariant, although the rates of CO desorption and subsequent physical sputtering were greatest for the heaviest (Ar+) ions. The ability of IBID to produce pure Pt films was confirmed by AES and XPS analysis of thin film deposits created by Ar+/Pt(CO)2Cl2, demonstrating the

Nanotechnological approaches for efficient N2B delivery: from small-molecule drugs to biopharmaceuticals

• Selin Akpinar Adscheid,
• Akif E. Türeli,
• Nazende Günday-Türeli and
• Marc Schneider

Beilstein J. Nanotechnol. 2024, 15, 1400–1414, doi:10.3762/bjnano.15.113

• [77]. In addition to biopolymers, synthetic biodegradable and biocompatible polymers such as poly(lactic acid) (PLA) and poly(lactic-co-glycolic acid) (PLGA), which are approved by the US Food and Drug Administration (FDA) for human administration [78] are relevant options. Extensive testing has been

• oligomeric chitosan for the co-delivery of alpha-cyano-4-hydroxycinnamic acid and the monoclonal antibody cetuximab to the brain for glioblastoma therapy. The cetuximab conjugation on the NP surface improved the cytotoxicity profile, and a chicken chorioallantoic membrane assay showed enhanced antiangiogenic

Hymenoptera and biomimetic surfaces: insights and innovations

• Vinicius Marques Lopez,
• Carlo Polidori and
• Rhainer Guillermo Ferreira

Beilstein J. Nanotechnol. 2024, 15, 1333–1352, doi:10.3762/bjnano.15.107

• the result of co-evolution of these traits with ecological requirements [56][92][93][94]. Furthermore, they are essentially in both intra- and interspecific communications [95][96][97]. These antennal sensors have inspired the development of devices for the detection of volatile compounds, which have

Interaction of graphene oxide with tannic acid: computational modeling and toxicity mitigation in C. elegans

• Romana Petry,
• James M. de Almeida,
• Francine Côa,
• Felipe Crasto de Lima,
• Diego Stéfani T. Martinez and
• Adalberto Fazzio

Beilstein J. Nanotechnol. 2024, 15, 1297–1311, doi:10.3762/bjnano.15.105

• biosynthesis protein COQ7 [51][53][54][55]. The co-exposure of GO with antioxidant molecules, such as ʟ-cysteine and ascorbate, can mitigate the oxidative effects of the material and minimize GO’s toxicity [35][53]. Moreover, GO also shows important neuronal effects; for example, it influences protein–protein

• tannic acid on the GO toxicity in a co-exposition system. The survival rates of C. elegans at GO concentrations ranging from 0.0001 to 10 mg·L−1 were analyzed in the presence of 1 and 10 mg·L−1 of TA. Figure 6 shows the survival rates of C. elegans after exposition to only GO and to GO in the presence of

Functional morphology of cleaning devices in the damselfly Ischnura elegans (Odonata, Coenagrionidae)

• Silvana Piersanti,
• Gianandrea Salerno,
• Wencke Krings,
• Stanislav Gorb and
• Manuela Rebora

Beilstein J. Nanotechnol. 2024, 15, 1260–1272, doi:10.3762/bjnano.15.102

• conventional lab freezer (ca. −20 °C) for 10 min. The foretibiae were cut from males and females by a scalpel. The specimens were washed in 70% ethanol and then immersed in glycerine (≥99.5%, Carl Roth GmbH & Co. KG, Karlsruhe, Germany). After fixing the specimens in glycerine between a glass slide and a cover

• slip (Carl Roth GmbH & Co. KG, Karlsruhe, Germany) for ca. 2 h, we visualized them with the CLSM (Zeiss LSM 700, Carl Zeiss Microscopy, Jena, Germany). The CLSM was equipped with four lasers (laser lines: 405, 488, 555, and 639 nm) to excite the sample fluorescence subsequently. Four emission filters

Realizing active targeting in cancer nanomedicine with ultrasmall nanoparticles

• André F. Lima,
• Giselle Z. Justo and
• Alioscka A. Sousa

Beilstein J. Nanotechnol. 2024, 15, 1208–1226, doi:10.3762/bjnano.15.98

• 9.3% ID/g at 4 and 24 h p.i., respectively. The importance of active targeting was demonstrated by co-injecting an excess of a high-affinity peptide agonist, resulting in approximately 50% blocking of tumor uptake. Tumor-bearing mice treated with targeted and radiolabeled C’ dots showed prolonged

• Nanocluster Enhanced Radiotherapy of Prostate Cancer”, Small, with permission from John Wiley and Sons. Copyright © 2019 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim. Germany. This content is not subject to CC BY 4.0. PET images detecting CCR2 in a mouse TNBC model using 64Cu-AuNCs-ECL1i. (A, B) Assessment of

• et al., “Chemokine Receptor 2 Targeted Gold Nanocluster Imaging Triple Negative Breast Cancer with Positron Emission Tomography”, Particle & Particle Systems Characterization, with permission from John Wiley and Sons. Copyright © 2021 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim. Germany. This content

AI-assisted models to predict chemotherapy drugs modified with C₆₀ fullerene derivatives

• Jonathan-Siu-Loong Robles-Hernández,
• Dora Iliana Medina,
• Katerin Aguirre-Hurtado,
• Marlene Bosquez,
• Roberto Salcedo and
• Alan Miralrio

Beilstein J. Nanotechnol. 2024, 15, 1170–1188, doi:10.3762/bjnano.15.95

• ][17]. This G-protein is targeted because studies show a possible positive effect on inhibiting the metastasis of cervical cancer cells [18]. However, more clinical and preclinical studies on CXCR7 and its co-player CXCR4 are required since alterations have been detected in diseases such as cancer

Photocatalytic methane oxidation over a TiO₂/SiNWs p–n junction catalyst at room temperature

• Qui Thanh Hoai Ta,
• Luan Minh Nguyen,
• Ngoc Hoi Nguyen,
• Phan Khanh Thinh Nguyen and
• Dai Hai Nguyen

Beilstein J. Nanotechnol. 2024, 15, 1132–1141, doi:10.3762/bjnano.15.92

• configuration advantages [34][35][36]. However, the wetness impregnation synthesis of those powder co-catalysts faces the issues of low surface area, low reproducibility, and difficult control of large-scale production. Therefore, the development of novel catalysts with unique morphologies by using precise

Direct electron beam writing of silver using a β-diketonate precursor: first insights

• Katja Höflich,
• Krzysztof Maćkosz,
• Chinmai S. Jureddy,
• Aleksei Tsarapkin and
• Ivo Utke

Beilstein J. Nanotechnol. 2024, 15, 1117–1124, doi:10.3762/bjnano.15.90

• ligands instead of their further dissociation and co-deposition into the deposit. To further investigate the microstructure of the deposit, a thin lamella along the dashed white line in Figure 1a was prepared and studied by TEM. The TEM overview image is depicted in Figure 1c, its alignment and

• in scanning electron microscopes during deposition, a double layer of water is still present on hydrophilic surfaces. This turns water into a natural co-reactant of direct electron beam writing [7] and helps in the formation of neutral volatile reaction products from the ligands, such as CO, CO2, CH4

• ). As this growth rate was only about two times larger than that of the thermal emitter, a precursor-limited growth regime and, thus, enhanced co-dissociation of the ligands is expected. For later TEM investigations, the deposition was carried out directly on a TEM grid. The STEM image in Figure 3 shows

Recent updates in applications of nanomedicine for the treatment of hepatic fibrosis

• Damai Ria Setyawati,
• Fransiska Christydira Sekaringtyas,
• Riyona Desvy Pratiwi,
• A’liyatur Rosyidah,
• Rohimmahtunnissa Azhar,
• Nunik Gustini,
• Gita Syahputra,
• Idah Rosidah,
• Etik Mardliyati,
• Tarwadi and
• Sjaikhurrizal El Muttaqien

Beilstein J. Nanotechnol. 2024, 15, 1105–1116, doi:10.3762/bjnano.15.89

• treatment. The enhanced permeability and retention (EPR) effect, first described by Maeda and co-workers in 1986, allows for high accumulation of the drug nanocarriers via the leaky vasculature and the deficient lymphatic system around solid tumors, as illustrated in the right panel of Figure 1 [3][4][5

• hydrophilicity [25]. For instance, the passive liver targeting strategy highly depends on the size of nanocarriers as the endothelial fenestrations of liver sinusoids span approximately 50–200 nm in diameter (Figure 2a). In their study, Hirn and co-workers revealed that 50% of small gold NPs (around 1.4 nm) were

• , resulting in poor bioavailability. Regarding synthetic substances, Kurniawan and co-workers encapsulated the potent inhibitor R406 to inhibit spleen tyrosine kinase in inflammatory macrophages using poly(lactic-co-glycolic acid) (PLGA) NPs (R406-PLGA) [45]. PLGA was used as polymeric platform as it is an

Unveiling the potential of alginate-based nanomaterials in sensing technology and smart delivery applications

• Shakhzodjon Uzokboev,
• Khojimukhammad Akhmadbekov,
• Ra’no Nuritdinova,
• Salah M. Tawfik and
• Yong-Ill Lee

Beilstein J. Nanotechnol. 2024, 15, 1077–1104, doi:10.3762/bjnano.15.88

Effect of wavelength and liquid on formation of Ag, Au, Ag/Au nanoparticles via picosecond laser ablation and SERS-based detection of DMMP

• Sree Satya Bharati Moram,
• Chandu Byram and
• Venugopal Rao Soma

Beilstein J. Nanotechnol. 2024, 15, 1054–1069, doi:10.3762/bjnano.15.86

• a smartphone application to detect DMMP. They detected DMMP at a concentration of 1g/L (≈8 mM) using a Raman excitation of 532 nm. Wang and co-workers [73] developed a novel method using thin water film confinement to enhance Raman detection of weakly interacting nerve agent simulants, such as DMMP

Interface properties of nanostructured carbon-coated biological implants: an overview

• Mattia Bartoli,
• Francesca Cardano,
• Erik Piatti,
• Stefania Lettieri,
• Andrea Fin and
• Alberto Tagliaferro

Beilstein J. Nanotechnol. 2024, 15, 1041–1053, doi:10.3762/bjnano.15.85

• materials In 2008, Lee and co-workers [32] stated that neat graphene was the strongest material ever tested with a tensile strength of 131 GPa and a Young’s modulus close to 1 TPa. The reason for these properties of graphene is the stability of the π-bond network around the hexagonal structures of carbon

• quantum confinement as reported by Bolker and co-workers [77]. Authors reported that the bandgap of NDs is strongly correlated to the NDs’ size, and it increases with decreasing crystallite size. However, the ND properties can be altered by heteroatomic doping and through the introduction of surface

• , suggesting that the ND coating prevented the removal of wear debris from coated implants. The complex relation between NDs and macrophage activity can be further tuned by functionalization with short molecules as reported by Pentecost and co-workers [90], who used small amines to tune the inflammatory

Beyond biomimicry – next generation applications of bioinspired adhesives from microfluidics to composites

• Dan Sameoto

Beilstein J. Nanotechnol. 2024, 15, 965–976, doi:10.3762/bjnano.15.79

• . © 2017 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim. This content is not subject to CC BY 4.0. Non-vacuum jamming based stiffness-tunable prototypes developed for use in space applications. Figure 6a–d were republished from [39] (“Controllable biomimetic adhesion using embedded phase change material

Therapeutic effect of F127-folate@PLGA/CHL/IR780 nanoparticles on folate receptor-expressing cancer cells

• Thi Ngoc Han Pham,
• Phuong-Thao Dang-Luong,
• Hong-Phuc Nguyen,
• Loc Le-Tuan,
• Xuan Thang Cao,
• Thanh-Danh Nguyen,
• Vy Tran Anh and
• Hieu Vu_Quang

Beilstein J. Nanotechnol. 2024, 15, 954–964, doi:10.3762/bjnano.15.78

• therapeutic and diagnostic capabilities, have gained significant interest in drug research because of to their potential advantages. This study reports the development of a novel multifunctional nanoparticle carrier system based on poly(ᴅ,ʟ-lactic-co-glycolic acid) (PLGA) for the targeted delivery of the

• and diagnosis, leveraging the advantages of PLGA, folate targeting, and the integration of therapeutic and imaging agents. Keywords: cancer; chlorambucil; drug carrier; IR780; PLGA nanoparticle; theragnostic; Introduction Poly(ᴅ,ʟ-lactic-co-glycolic acid) (PLGA), a copolymer of poly(lactic acid

• ]. It has been found that PLGA may co-encapsulate a range of hydrophobic and hydrophilic compounds, which, because of the core–shell structures, boosts their therapeutic anti-tumor activity [1][2][3][11][26][27][28][29][30][31][32][33]. In this study, we would want to combine all of the advantages of

Electrospun nanofibers: building blocks for the repair of bone tissue

• Tuğrul Mert Serim,
• Gülin Amasya,
• Tuğba Eren-Böncü,
• Ceyda Tuba Şengel-Türk and
• Ayşe Nurten Özdemir

Beilstein J. Nanotechnol. 2024, 15, 941–953, doi:10.3762/bjnano.15.77

• Co. Ltd.)) [101]. The main polymeric nanofiber products on the market for bone regeneration are ReBOSSIS (Ortho Rebirth, Japan), a PLGA-based biomedical product for filling a synthetic bone cavity, poly-ʟ-lactic acid (PLLA) and collagen scaffolds (The Electrospinning Company, United Kingdom), and PCL

Effects of cutting tool geometry on material removal of a gradient nanograined CoCrNi medium entropy alloy

• Yu-Sheng Lu,
• Yu-Xuan Hung,
• Thi-Xuyen Bui and
• Te-Hua Fang

Beilstein J. Nanotechnol. 2024, 15, 925–940, doi:10.3762/bjnano.15.76

• MEA, as shown in Figure 1. FCC phase GNG CoCrNi MEA substrates with dimensions of 3 nm × 30 nm × 10 nm were used for all cases in this study. The polycrystalline samples consist of randomly oriented grains. The MEA substrates contain 25,952 Co atoms, 26,628 Cr, and 26,746 Ni atoms. Hence, the alloy

Facile synthesis of Fe-based metal–organic frameworks from Fe₂O₃ nanoparticles and their application for CO₂/N₂ separation

• Van Nhieu Le,
• Hoai Duc Tran,
• Minh Tien Nguyen,
• Hai Bang Truong,
• Toan Minh Pham and
• Jinsoo Kim

Beilstein J. Nanotechnol. 2024, 15, 897–908, doi:10.3762/bjnano.15.74

• manufacturing cost, environmental friendliness, and biodegradability. Because of the abovementioned advantages, MIL-100(Fe) has gained popularity as a candidate for gas separation of CO/CO2 [9][13], CO/N2 [14][15], CO2/CH4 [16], CH4/C2H6/C3H8 [17], and SF6/N2 [18]. In the early stage, MIL-100(Fe) was produced