Efficiency of single-pulse laser fragmentation of organic nutraceutical dispersions in a circular jet flow-through reactor

• Tina Friedenauer,
• Maximilian Spellauge,
• Alexander Sommereyns,
• Verena Labenski,
• Tuba Esatbeyoglu,
• Christoph Rehbock,
• Heinz P. Huber and
• Stephan Barcikowski

Beilstein J. Nanotechnol. 2025, 16, 711–727, doi:10.3762/bjnano.16.55

• diketone moiety, initiating the formation of vanillin and ferulic acid [57][58]. This is in line with the formation of lower molecular weight products indicated in Figures S7–S9, Supporting Information File 1. Furthermore, polymerization of these phenolic compounds is reported [58], which is verified by

Nanomaterials in targeting amyloid-β oligomers: current advances and future directions for Alzheimer's disease diagnosis and therapy

• Shiwani Randhawa,
• Trilok Chand Saini,
• Manik Bathla,
• Rahul Bhardwaj,
• Rubina Dhiman and
• Amitabha Acharya

Beilstein J. Nanotechnol. 2025, 16, 561–580, doi:10.3762/bjnano.16.44

• process, as illustrated in Figure 1. The first two pathways fall under the “on-pathway” model, which includes nucleated polymerization and nucleated conformational conversion. These models suggest that oligomers are transient species that form as intermediates during the transition from monomers to mature

Synthetic-polymer-assisted antisense oligonucleotide delivery: targeted approaches for precision disease treatment

• Ana Cubillo Alvarez,
• Dylan Maguire and
• Ruairí P. Brannigan

Beilstein J. Nanotechnol. 2025, 16, 435–463, doi:10.3762/bjnano.16.34

• )) targeting solid tumours [66]. Triblock copolymers comprising poly(2-ethyl-2-oxazoline) (PEtOx), poly(2-n-propyl-2-oxazoline) (PnPrOx), and PLL (Mw = 6.9 kDa, degree of polymerization (DP) = 42) segments allowed for the formation of compartmentalised micelles bearing a hydrophilic PEtOx shell, a

Engineered PEG–PCL nanoparticles enable sensitive and selective detection of sodium dodecyl sulfate: a qualitative and quantitative analysis

• Soni Prajapati and
• Ranjana Singh

Beilstein J. Nanotechnol. 2025, 16, 385–396, doi:10.3762/bjnano.16.29

• , labor-intensive, and require specialized technical expertise. This study developed a novel colorimetric method for the selective and sensitive detection of SDS, utilizing polyethylene glycol-polycaprolactone nanoparticles (PEG–PCL NPs) synthesized via a ring-opening polymerization approach. The

• vigorously stirred in a silicon oil bath at 130 °C. Subsequently, a syringe introduced 2 mL of ε-caprolactone and 1 mL of stannous octoate (as a reaction catalyst) into the molten mPEG. The polymerization reaction was conducted under vacuum with continuous stirring at 130 °C for 24 h. After the

• polymerization, the resulting complexes were cooled down to room temperature, dissolved in DCM, and precipitated using an excess of cold diethyl ether. The precipitates were isolated by filtration using filter paper and dried under vacuum. The collected PEG–PCL NPs were then subjected to further characterization

Enhancing mechanical properties of chitosan/PVA electrospun nanofibers: a comprehensive review

• Nur Areisman Mohd Salleh,
• Amalina Muhammad Afifi,
• Fathiah Mohamed Zuki and
• Hanna Sofia SalehHudin

Beilstein J. Nanotechnol. 2025, 16, 286–307, doi:10.3762/bjnano.16.22

• blending of functional agents in the polymer solution, wet chemical methods, surface graft polymerization, and plasma treatment [160]. Low-temperature plasma offers advantages over other techniques in terms of lower energy consumption, faster processing, and minimal solvent use [161]. By appropriately

• number of adsorption sites on the surface, improve mechanical properties, enhance hydrophilicity and wettability, and stabilize nanofibers in aqueous solutions [156]. Numerous techniques have been developed to modify the surface properties of electrospun nanofibers, including surface graft polymerization

Synthesis and the impact of hydroxyapatite nanoparticles on the viability and activity of rhizobacteria

• Bedah Rupaedah,
• Indrika Novella,
• Atiek Rostika Noviyanti,
• Diana Rakhmawaty Eddy,
• Anna Safarrida,
• Abdul Hapid,
• Zhafira Amila Haqqa,
• Suryana Suryana,
• Irwan Kurnia and
• Fathiyah Inayatirrahmi

Beilstein J. Nanotechnol. 2025, 16, 216–228, doi:10.3762/bjnano.16.17

• cycles consisting of denaturation at 94 °C for 45 s, annealing at 52 °C for 1 min, and elongation at 72 °C for 1 min. After the final cycle, polymerization continued at 72 °C for 5 min. The PCR products were then analyzed by electrophoresis on a 1% agarose gel. Visualization was performed under UV light

A review of metal-organic frameworks and polymers in mixed matrix membranes for CO₂ capture

• Charlotte Skjold Qvist Christensen,
• Nicholas Hansen,
• Mahboubeh Motadayen,
• Nina Lock,
• Martin Lahn Henriksen and
• Jonathan Quinson

Beilstein J. Nanotechnol. 2025, 16, 155–186, doi:10.3762/bjnano.16.14

• linkers are rigid and contain at least two functional groups, which allow for their polymerization with the metal ions to form stable and well-defined 3D structures. A plethora of different linkers (e.g., 2,5-dioxido-1,4-benzenedicarboxylic acid (H2DOBDC), 1,3,5-benzenetricarboxylic acid (H3BTC), and 1,4

TiO₂ immobilized on 2D mordenite: effect of hydrolysis conditions on structural, textural, and optical characteristics of the nanocomposites

• Marina G. Shelyapina,
• Rosario Isidro Yocupicio-Gaxiola,
• Gleb A. Valkovsky and
• Vitalii Petranovskii

Beilstein J. Nanotechnol. 2025, 16, 128–140, doi:10.3762/bjnano.16.12

• derivatives compared to Si(OR)4 leads to a high propensity for oligomerization and polymerization of metal alkoxides after the first stages of hydrolysis. In the case of tetraethoxysilane, the overall reaction can be written as [29]: The situation in the case of titanium alkoxides is more ambiguous. In a

Bioinspired nanofilament coatings for scale reduction on steel

• Siad Dahir Ali,
• Mette Heidemann Rasmussen,
• Jacopo Catalano,
• Christian Husum Frederiksen and
• Tobias Weidner

Beilstein J. Nanotechnol. 2025, 16, 25–34, doi:10.3762/bjnano.16.3

• polymerization of a polysiloxane on the material surface [18]. The polysiloxane methyl groups lower the surface energy and render the surface hydrophobic. Clearly, the surface chemistry of steel surfaces is very different from the previously used materials such as glass [11][12][13][18], polymers [10][11][12

• ], and textiles [11][12][13][14][15][16] as it does not offer the hydroxy moieties used previously for direct surface polymerization. It is therefore important to carefully test the stability and attachment of any SNFs growing on steel surfaces. Mechanical scratching of the coated steel surface will

A biomimetic approach towards a universal slippery liquid infused surface coating

• Ryan A. Faase,
• Madeleine H. Hummel,
• AnneMarie V. Hasbrook,
• Andrew P. Carpenter and
• Joe E. Baio

Beilstein J. Nanotechnol. 2024, 15, 1376–1389, doi:10.3762/bjnano.15.111

• fabrication of SLIPS by producing the required lubricant anchor layer through the polymerization of dopamine. This dopamine polymerization step is extremely simple and will form a “sticky” layer to almost any chemistry, thereby, providing a straightforward process to produce a SLIPS layer on almost any

• roughness of all samples with the final layer of the coating were not significantly different from one another, suggesting universal attachment of the SLIPS porous component. The final structure of oxidative polymerization for dopamine into PDA is not fully agreed upon [20][44][45]. Therefore, information

• , previous studies investigating SLIPS-induced fibrin polymerization found a significant reduction compared to bare surfaces [4]. There was significant variation between donors and between runs, but the trends remained consistent. Differences between runs were not of interest, so data was normalized to the

Synthesis, characterization and anticancer effect of doxorubicin-loaded dual stimuli-responsive smart nanopolymers

• Ömür Acet,
• Pavel Kirsanov,
• Burcu Önal Acet,
• Inessa Halets-Bui,
• Dzmitry Shcharbin,
• Şeyda Ceylan Cömert and
• Mehmet Odabaşı

Beilstein J. Nanotechnol. 2024, 15, 1189–1196, doi:10.3762/bjnano.15.96

• humidified air atmosphere with 5% CO2. Preparation of DOX-SNPs To synthesize DOX-containing nanoparticle structures, the miniemulsion polymerization method was used according to a protocol adapted from [24]. First, the water phase was formed. The water phase was obtained by adding and dissolving 0.375 g

• 0.230 g NaHSO3 (solution D) were added to the medium, and polymerization was initiated. After about 10 h of polymerization, the surfactants and unreacted monomers were washed out with the help of an ethanol–water mixture, and the mixture was centrifuged at 25,000 rpm (Beckman Coulter, Allegra 64R

• . The data shows that smart nanopolymers can be used to create new types of doxorubicin-based drugs. Solutions utilized during polymerization. FTIR spectra of SNPs and DOX-SNPs. SEM image of SNPs. (A) Loading capacity of DOX at different initial concentrations. (B) Time-dependent release of DOX under

Unveiling the potential of alginate-based nanomaterials in sensing technology and smart delivery applications

• Shakhzodjon Uzokboev,
• Khojimukhammad Akhmadbekov,
• Ra’no Nuritdinova,
• Salah M. Tawfik and
• Yong-Ill Lee

Beilstein J. Nanotechnol. 2024, 15, 1077–1104, doi:10.3762/bjnano.15.88

• -aminophenyl boronic acid)/sodium alginate nanogel (Ag@PABA-SA) was synthesized using a green, in situ chemical oxidative polymerization approach for detecting hydrogen peroxide in lake water [115]. When this experiment was carried out without alginate, it showed unsuccessful results. Importantly, with

Electrospun nanofibers: building blocks for the repair of bone tissue

• Tuğrul Mert Serim,
• Gülin Amasya,
• Tuğba Eren-Böncü,
• Ceyda Tuba Şengel-Türk and
• Ayşe Nurten Özdemir

Beilstein J. Nanotechnol. 2024, 15, 941–953, doi:10.3762/bjnano.15.77

• the literature including inter-surface polymerization, phase separation, drawing, self-assembly, melt blowing, template melt extrusion, forcespinning, and electrospinning [36][37][38][39][40]. Only electrospinning will be further explained in detail in order to remain within the scope. Electrospinning

Intermixing of MoS₂ and WS₂ photocatalysts toward methylene blue photodegradation

• Maryam Al Qaydi,
• Nitul S. Rajput,
• Michael Lejeune,
• Abdellatif Bouchalkha,
• Mimoun El Marssi,
• Steevy Cordette,
• Chaouki Kasmi and
• Mustapha Jouiad

Beilstein J. Nanotechnol. 2024, 15, 817–829, doi:10.3762/bjnano.15.68

• oxidative polymerization achieved a photodegradation efficiency of 96.15% in 180 min by using 100 mg of the catalyst to degrade 5 mg/L of MB [25]. Nevertheless, most of the reported studies concerned the use of complex heterostructure-based devices and a very high quantity of catalysts, which is not

Laser synthesis of nanoparticles in organic solvents – products, reactions, and perspectives

• Theo Fromme,
• Sven Reichenberger,
• Katharine M. Tibbetts and
• Stephan Barcikowski

Beilstein J. Nanotechnol. 2024, 15, 638–663, doi:10.3762/bjnano.15.54

• solvent and shockwaves can initiate bimolecular reactions that primarily lead to dimerization but also allow for fragmentation, polymerization, and other reactions to occur [52]. Figure 1 schematically summarizes the classification of LSPC methods and the generated particles (left side), and by-products

• , metallic glasses, or intermetallics can be synthesized. The origin of the formed carbon can be traced back to chemical reactions during the LSPC, which have been reported to be pyrolysis, di-/trimerization, and polymerization. The by-products of these reactions can be either liquid hydrocarbons, for

• and benzene, both prone to polymerization reactions and coke formation, showed the largest hydrogen production, while cyclohexane and cyclohexene released the lowest amount of hydrogen compared to other C6 solvents. Interestingly, ablation in n-pentane produced the least amount of hydrogen of all

Electron-induced deposition using Fe(CO)₄MA and Fe(CO)₅ – effect of MA ligand and process conditions

• Hannah Boeckers,
• Atul Chaudhary,
• Petra Martinović,
• Amy V. Walker,
• Lisa McElwee-White and
• Petra Swiderek

Beilstein J. Nanotechnol. 2024, 15, 500–516, doi:10.3762/bjnano.15.45

• such larger species can still lead to the release of H2 and possibly also of CO [53]. However, such polymerization reactions would be expected to lead to retention of a considerable amount of carbon in a deposit produced by electron irradiation of Fe(CO)4MA, which is not supported by the AES results

• might be more easily trapped in such thick layers and, thus, be more prone to electron-induced polymerization as reported for condensed layers of MMA [50]. We also note that the somewhat higher amount of carbon and oxygen suggested by the compositions derived from the EBID experiments as compared to

• the amount of carbon in the MA ligand. This result also indicates that electron-induced polymerization of the MA ligands does not play a major role in deposit formation. In contrast, the low carbon content and a delayed desorption of CO in later stages of ESD suggest that the MA ligand is efficiently

Vinorelbine-loaded multifunctional magnetic nanoparticles as anticancer drug delivery systems: synthesis, characterization, and in vitro release study

• Zeynep Özcan and
• Afife Binnaz Hazar Yoruç

Beilstein J. Nanotechnol. 2024, 15, 256–269, doi:10.3762/bjnano.15.24

• using a solvothermal method. Subsequently, Fe3O4 NPs were coated with PDA in different ratios. The coating process involved the use of PDA in ratios of 1:1, 2:1, and 4:1, respectively. PDA can undergo polymerization resulting in the adsorption onto the surface of the negatively charged Fe3O4 NPs [22

• incorporated in the structure of PDA/Fe3O4 NPs during the polymerization of dopamine. It was observed that a significant portion of VNB in VNB/PDA/Fe3O4 NPs was absorbed within the polymer shell, while a small portion was retained on the surface [52]. According to FTIR analyses, drug-related features are

• critical aspect that warrants attention is the potential impact of different pH values on the oxidative capacity of the coating material polydopamine. This coating, formed through the polymerization of dopamine, plays a pivotal role in the drug delivery system. The variations in pH values can potentially

Nanotechnological approaches in the treatment of schistosomiasis: an overview

• Lucas Carvalho,
• Michelle Sarcinelli and
• Beatriz Patrício

Beilstein J. Nanotechnol. 2024, 15, 13–25, doi:10.3762/bjnano.15.2

• polymers or the polymerization of monomers [17]. The first one is more commonly describe in the literature, and the techniques usually employed to produce them include nanoprecipitation, solvent evaporation, emulsification/solvent diffusion, and emulsification/reverse salting out [18][19]. The main

Fluorescent bioinspired albumin/polydopamine nanoparticles and their interactions with Escherichia coli cells

• Eloïse Equy,
• Jordana Hirtzel,
• Sophie Hellé,
• Béatrice Heurtault,
• Eric Mathieu,
• Morgane Rabineau,
• Vincent Ball and
• Lydie Ploux

Beilstein J. Nanotechnol. 2023, 14, 1208–1224, doi:10.3762/bjnano.14.100

• hydrodynamic diameter of 3–4 nm at physiological pH [20]. The resulting number N of nanoparticles per milliliter and self-polymerization reaction yield η obtained with BSA/DA ratios of 3 and 10 were calculated with Equation 1 and Equation 2, respectively: where V is the volume of the NP solution remainder

• -polymerization of dopamine to (b) polydopamine or (c) to polydopamine nanoparticles in the presence of BSA (inspired from [13]). (d) Synthesis principle and photographic images of suspensions of fluorescent Ox-BSA/PDA NPs obtained by oxidation of pristine BSA/PDA NPs. (e) Synthesis principles and photographic

Hierarchically patterned polyurethane microgrooves featuring nanopillars or nanoholes for neurite elongation and alignment

• Lester Uy Vinzons,
• Guo-Chung Dong and
• Shu-Ping Lin

Beilstein J. Nanotechnol. 2023, 14, 1157–1168, doi:10.3762/bjnano.14.96

• ), which were also visible under an optical (metallurgical) microscope (Supporting Information File 1, Figure S3A). This was probably due to the polymerization of uncrosslinked PDMS in the mold nanoholes when the PDMS expands during PU casting (Supporting Information File 1, Figure S3B). When lots of short

Recognition mechanisms of hemoglobin particles by monocytes – CD163 may just be one

• Jonathan-Gabriel Nimz,
• Pichayut Rerkshanandana,
• Chiraphat Kloypan,
• Ulrich Kalus,
• Saranya Chaiwaree,
• Axel Pruß,
• Radostina Georgieva,
• Yu Xiong and
• Hans Bäumler

Beilstein J. Nanotechnol. 2023, 14, 1028–1040, doi:10.3762/bjnano.14.85

• HBOCs have been devised. Crosslinking of different Hb chains, polymerization of Hb molecules [16][17][18], surface modification [19], and techniques for encapsulation [20][21] already brought us somewhat closer towards a safe use of HBOCs [22]. However, a persistent problem is the severely limited

• fractions (32 kDa to >600 kDa) was shown. Also polymerization, cross-linking, and cross-linking sites influenced the receptor’s affinity for individual HBOCs, while the origin of the utilized Hb seemed to be of no relevance [16]. Furthermore size dependence probably exists also in antibody-induced

Antibody-conjugated nanoparticles for target-specific drug delivery of chemotherapeutics

• Mamta Kumari,
• Amitabha Acharya and
• Praveen Thaggikuppe Krishnamurthy

Beilstein J. Nanotechnol. 2023, 14, 912–926, doi:10.3762/bjnano.14.75

• increasing the antigen binding capacity and the conjugation efficiency [61]. These covalent conjugation methods are highly stable but associated with some drawbacks. These include aggregation and polymerization, cross-linking at multiple sites on the antibodies, the need for additional purification steps for

Industrial perspectives for personalized microneedles

• Remmi Danae Baker-Sediako,
• Benjamin Richter,
• Matthias Blaicher,
• Michael Thiel and
• Martin Hermatschweiler

Beilstein J. Nanotechnol. 2023, 14, 857–864, doi:10.3762/bjnano.14.70

• microneedles may become personalized according to a patient’s demographic in order to increase drug delivery efficiency and reduce healing times for patient-centric care. Keywords: 3D printing; microfabrication; microneedles; personalized medicine; transdermal drug delivery; two-photon polymerization

• that can overcome these challenges [27]. Specifically, light-based 3D printing techniques such as stereolithography (SLA), digital light processing (DLP), and two-photon polymerization (2PP) simplify the rapid prototyping workflow when compared to traditional micro- and nanofabrication methods [28][29

• objective) and large (ZEISS 10x NA 0.8 objective) feature sets. IPX-Q and IP-S are methacrylate photoresins; after polymerization, both materials are non-cytotoxic, as certified via external ISO-10993-5 commissioning. IP-S is a photoresin optimized for printing smooth microoptics with the medium solution

Conjugated photothermal materials and structure design for solar steam generation

• Chia-Yang Lin and
• Tsuyoshi Michinobu

Beilstein J. Nanotechnol. 2023, 14, 454–466, doi:10.3762/bjnano.14.36

• formed by sequential polymerization on paper substrates, to enhance their light capturing capability (Figure 6a) [32]. Transmission and diffuse reflectance measurements of the PPy nanosheets confirmed that the multilayer PPy nanosheets on the paper substrate exhibited a distinct broadband absorption in

• room temperature to produce APDA. During the polymerization, DHI or IQ moieties were formed by rearrangement of dopamine. The formed DHI and IQ moieties then reacted with each other or the amine groups of arginine. This was followed by further polymerization of DHI, IQ, arginine, and their oligomers

Molecular nanoarchitectonics: unification of nanotechnology and molecular/materials science

• Katsuhiko Ariga

Beilstein J. Nanotechnol. 2023, 14, 434–453, doi:10.3762/bjnano.14.35

• creating a self-assembled monolayer of a diacetylene compound (10,12-nonacosazinoic acid) adsorbed on a graphite surface and biased with a scanning tunneling microscope probe [111]. By positioning the probe at a specific site, the polymerization of the chains was induced within defined small regions, and

• the propagation of a linear polymerization reaction was successfully initiated and terminated at an arbitrary point. In other words, the polymerization reaction can be triggered at a desired position on the surface. If nanoscale processing and connections can be precisely controlled in this way

• , molecular nanoelectronics beyond current silicon-based device technologies can be realized. It also provides new scientific opportunities, such as measuring electrical conduction in structurally perfect one-dimensional materials and analyzing the propagation mechanism of chain polymerization. Thus, various