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Search for "aggregation" in Full Text gives 434 result(s) in Beilstein Journal of Nanotechnology. Showing first 200.

Polymer lipid hybrid nanoparticles for phytochemical delivery: challenges, progress, and future prospects

  • Iqra Rahat,
  • Pooja Yadav,
  • Aditi Singhal,
  • Mohammad Fareed,
  • Jaganathan Raja Purushothaman,
  • Mohammed Aslam,
  • Raju Balaji,
  • Sonali Patil-Shinde and
  • Md. Rizwanullah

Beilstein J. Nanotechnol. 2024, 15, 1473–1497, doi:10.3762/bjnano.15.118

Graphical Abstract
  • . This modification provides several advantages. PEGylation increases the stability of the PLHNPs in biological fluids by preventing aggregation and reducing protein adsorption. It also extends the circulation time of nanoparticles in the bloodstream by reducing immune system recognition and clearance
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Published 22 Nov 2024

Nanoarchitectonics with cetrimonium bromide on metal nanoparticles for linker-free detection of toxic metal ions and catalytic degradation of 4-nitrophenol

  • Akash Kumar and
  • Raja Gopal Rayavarapu

Beilstein J. Nanotechnol. 2024, 15, 1312–1332, doi:10.3762/bjnano.15.106

Graphical Abstract
  • environments or functional groups [3]. Surfactants bind to metal surfaces and create a stable colloidal solution by preventing the nanoparticles from aggregation or clustering [4]. CTAB is a widely used cationic surfactant that provides nanoparticle ionic stability and anisotropy [5]. Although CTAB delivers
  • due to the larger inter-micellar channels generated on the flat side facets of the gold nanorods [37]. In comparison, the CTAB molecules on the longer nanorods are scattered over the side faces of the nanorods, which may lead to aggregation. Changes in pH or ionic strength are also capable of
  • decreasing the CTAB binding to surfaces of longer gold nanorods. Therefore, longer nanorods are more prone to aggregation than shorter rods. The packing density of CTAB is also reported to be a factor that controls the size of metal nanoparticles [38]. The isotropic gold nanospheres exhibit an equal
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Published 04 Nov 2024

Interaction of graphene oxide with tannic acid: computational modeling and toxicity mitigation in C. elegans

  • Romana Petry,
  • James M. de Almeida,
  • Francine Côa,
  • Felipe Crasto de Lima,
  • Diego Stéfani T. Martinez and
  • Adalberto Fazzio

Beilstein J. Nanotechnol. 2024, 15, 1297–1311, doi:10.3762/bjnano.15.105

Graphical Abstract
  • relevance of GO, it is necessary to ensure its safe application, disposal, and regulation. This begins with understanding the behavior of this material in the environment and its impact on living organisms. Once in a biological/environmental medium, GO undergoes processes such as aggregation
  • GO surface composition after interaction with TA. Colloidal Stability The study of the colloidal behavior of the material in relevant biological media (regarding, e.g., salinity, pH, or biomolecules) is essential to understand its toxicological outcomes since the aggregation state of this material
  • directly affects delivered dose, internalization, and biodistribution in organisms. In the EPA medium, GO exhibited aggregation and precipitation at concentrations of 5.0 and 10 mg·L−1, respectively, a phenomenon attributable to the screening effect of salt ions diminishing the repulsive forces between GO
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Published 30 Oct 2024

Dual-functionalized architecture enables stable and tumor cell-specific SiO2NPs in complex biological fluids

  • Iris Renata Sousa Ribeiro,
  • Raquel Frenedoso da Silva,
  • Romênia Ramos Domingues,
  • Adriana Franco Paes Leme and
  • Mateus Borba Cardoso

Beilstein J. Nanotechnol. 2024, 15, 1238–1252, doi:10.3762/bjnano.15.100

Graphical Abstract
  • increase in the hydrodynamic diameter for the SiO2NPs-ZW-FO may be associated with their subtle aggregation after the addition of folate or simply by the change in the dynamic structure of the particle since folate is hydrophobic [35] and can alter the arrangement of water molecules around the NP. Zeta
  • degree of SiO2NPs-ZW-FO aggregation or even the possibility of folate hiding some negative charges on the NP surface. In short, it was impossible to confirm the steps of the SiO2NP functionalization process through zeta potential measurements. Elemental analysis and XPS techniques were further used to
  • (Figure 2b,c,d), both non-functionalized and functionalized SiO2NPs (0.5 mg·mL–1) remained stable in DMEM supplemented with 10% FBS after a 24 h incubation period, showing only a subtle aggregation. Therefore, it is impossible to conclude that ZW promoted the colloidal stability of NPs since the non
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Published 07 Oct 2024

Enhanced catalytic reduction through in situ synthesized gold nanoparticles embedded in glucosamine/alginate nanocomposites

  • Chi-Hien Dang,
  • Le-Kim-Thuy Nguyen,
  • Minh-Trong Tran,
  • Van-Dung Le,
  • Nguyen Minh Ty,
  • T. Ngoc Han Pham,
  • Hieu Vu-Quang,
  • Tran Thi Kim Chi,
  • Tran Thi Huong Giang,
  • Nguyen Thi Thanh Tu and
  • Thanh-Danh Nguyen

Beilstein J. Nanotechnol. 2024, 15, 1227–1237, doi:10.3762/bjnano.15.99

Graphical Abstract
  • at the SPR band, indicative of increased AuNP formation, while the λmax values exhibited insignificant changes (Figure 2A,B). However, at higher Au3+-to-gel ratios (9%), we observed the presence of solid material after synthesis, likely due to nanocomposite aggregation. Therefore, to achieve
  • absorbance declines again at higher temperatures (80 and 90 °C). This decrease in AuNP concentration in the colloidal solution is attributed to nanoparticle aggregation. Elevated temperatures can cause the detachment of the polysaccharide chains from the surface of the AuNPs, promoting the collision and
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Published 04 Oct 2024

Introducing third-generation periodic table descriptors for nano-qRASTR modeling of zebrafish toxicity of metal oxide nanoparticles

  • Supratik Kar and
  • Siyun Yang

Beilstein J. Nanotechnol. 2024, 15, 1142–1152, doi:10.3762/bjnano.15.93

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  • , through aggregation, cause localized toxicity to zebrafish. Additionally, their size affects biodistribution and clearance, with larger MONPs tending to accumulate within the zebrafish organism, further exacerbating toxicity (Figure 3). In zebrafish, these mechanisms can manifest in several ways
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Published 10 Sep 2024

Unveiling the potential of alginate-based nanomaterials in sensing technology and smart delivery applications

  • Shakhzodjon Uzokboev,
  • Khojimukhammad Akhmadbekov,
  • Ra’no Nuritdinova,
  • Salah M. Tawfik and
  • Yong-Ill Lee

Beilstein J. Nanotechnol. 2024, 15, 1077–1104, doi:10.3762/bjnano.15.88

Graphical Abstract
  • for glucose detection [131]. The high colloidal stability of alginate-based nanoparticles ensures their long-term stability and prevents aggregation, leading to more reliable and consistent glucose detection results [141]. Alginate-based nanoparticles can be easily functionalized to enhance their
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Published 22 Aug 2024

Effect of wavelength and liquid on formation of Ag, Au, Ag/Au nanoparticles via picosecond laser ablation and SERS-based detection of DMMP

  • Sree Satya Bharati Moram,
  • Chandu Byram and
  • Venugopal Rao Soma

Beilstein J. Nanotechnol. 2024, 15, 1054–1069, doi:10.3762/bjnano.15.86

Graphical Abstract
  • wavelengths (1064 nm). This broadening could be ascribed to the size/shape of the NPs, their aggregation, and variations in size distribution under different laser wavelengths. The NP productivity in the LASiS approach is mainly influenced by laser wavelength irradiation based on the interaction of the
  • , and aggregation variations, ultimately impacting their optical properties [53]. Also, from absorbance studies, it is observed that the ablation rate is higher for the Au target than for Ag because of the hardness variation observed in an earlier report by Solati et al. [54]. In another study by Bae et
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Published 19 Aug 2024

Interface properties of nanostructured carbon-coated biological implants: an overview

  • Mattia Bartoli,
  • Francesca Cardano,
  • Erik Piatti,
  • Stefania Lettieri,
  • Andrea Fin and
  • Alberto Tagliaferro

Beilstein J. Nanotechnol. 2024, 15, 1041–1053, doi:10.3762/bjnano.15.85

Graphical Abstract
  • bacteria according to the mechanism shown in Figure 4. The biofilm formation consists of four stages, namely, (i) adhesion, (ii) aggregation, (iii) maturation, and (iv) dispersion. Adhesion is the first step and is ruled by the polarity of the surface as reported by Gittens and co-workers [105]. The
  • aggregation and maturation steps involve the formation and enlargement of bacteria colonies enclosed in the extracellular biopolymeric matrix [106]. Dispersion occurs upon reaching the biofilm’s critical mass, allowing for the partial detachment and spread of infection through the bloodstream [31]. Carbon
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Published 16 Aug 2024

Therapeutic effect of F127-folate@PLGA/CHL/IR780 nanoparticles on folate receptor-expressing cancer cells

  • Thi Ngoc Han Pham,
  • Phuong-Thao Dang-Luong,
  • Hong-Phuc Nguyen,
  • Loc Le-Tuan,
  • Xuan Thang Cao,
  • Thanh-Danh Nguyen,
  • Vy Tran Anh and
  • Hieu Vu_Quang

Beilstein J. Nanotechnol. 2024, 15, 954–964, doi:10.3762/bjnano.15.78

Graphical Abstract
  • . The outer PEO corona prevents aggregation, protein adsorption, and recognition by the reticuloendothelial system, while the hydrophobic PPO core may be modified to contain hydrophobic anticancer drugs, fluorophores, or even anchor to the hydrophobic layer of the nanoparticles [8][9]. The F127
  • of F127 associates with or anchors to hydrophobic PLGA, while the hydrophilic block PEO exposed to the aqueous environment associates with or anchors to hydrophilic PLGA [9][10]. The PEO block yields a stealthy surface that inhibits protein adsorption and aggregation. In addition, the conjugation of
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Published 31 Jul 2024

A review on the structural characterization of nanomaterials for nano-QSAR models

  • Salvador Moncho,
  • Eva Serrano-Candelas,
  • Jesús Vicente de Julián-Ortiz and
  • Rafael Gozalbes

Beilstein J. Nanotechnol. 2024, 15, 854–866, doi:10.3762/bjnano.15.71

Graphical Abstract
  • light scattering (DLS) is another technique that can be used to describe the hydrodynamic size or the aggregation of the nanoforms in larger nanostructures, depending on the medium and other conditions. In some cases, the size values reported in the papers are not measured on purpose, but are the
  • calculated, numerical factors derived from the size of the molecule and other physicochemical properties of its components. For example, a series of size-dependent descriptors, such as the ratio of surface molecules, which involves both the nanoform size and the aggregation size, can be calculated using a
  • of the endpoint. The exposure of the NMs to different conditions could produce structural changes, which could be responsible for changes in their activity. The NM particles are known to be significantly affected by the medium regarding size, aggregation, ligands, and nanostructure. Nevertheless
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Published 11 Jul 2024

Synthesis of silver–palladium Janus nanoparticles using co-sputtering of independent sources: experimental and theorical study

  • Maria J. Martínez-Carreón,
  • Francisco Solís-Pomar,
  • Abel Fundora,
  • Claudio D. Gutiérrez-Lazos,
  • Sergio Mejía-Rosales,
  • Hector N. Fernández-Escamilla,
  • Jonathan Guerrero-Sánchez,
  • Manuel F. Meléndrez and
  • Eduardo Pérez-Tijerina

Beilstein J. Nanotechnol. 2024, 15, 808–816, doi:10.3762/bjnano.15.67

Graphical Abstract
  • evaporated concurrently in the aggregation region, which results in the formation of nanoparticles with a variety of structural motifs, such as randomly alloyed, core–shell, and Janus nanoparticles [2]. The study of bimetallic nanoparticles (BNPs) is highly interesting for the scientific community because of
  • copper grids in an argon flow at 52 sscm for 5 min at room temperature. The size of the BNPs can be modified by varying three parameters, namely, aggregation area, magnetron power, and partial pressure. The chosen parameters for both magnetrons are presented in Table 1. HRTEM micrographs were obtained
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Published 04 Jul 2024

Gold nanomakura: nanoarchitectonics and their photothermal response in association with carrageenan hydrogels

  • Nabojit Das,
  • Vikas,
  • Akash Kumar,
  • Sanjeev Soni and
  • Raja Gopal Rayavarapu

Beilstein J. Nanotechnol. 2024, 15, 678–693, doi:10.3762/bjnano.15.56

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  • do not require aggregation to generate hotspots due to readily obtained tunability of higher aspect ratios during synthesis [13]. Engineering of anisotropic AuNPs with controlled aspect ratio has therefore become an emerging topic for research. Anisotropic gold nanoparticles due to their ability to
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Published 07 Jun 2024

Laser synthesis of nanoparticles in organic solvents – products, reactions, and perspectives

  • Theo Fromme,
  • Sven Reichenberger,
  • Katharine M. Tibbetts and
  • Stephan Barcikowski

Beilstein J. Nanotechnol. 2024, 15, 638–663, doi:10.3762/bjnano.15.54

Graphical Abstract
  • accessibility and, thereby, slowing down oxidation, providing conductivity via carbon shells, or providing steric stability against aggregation. Regardless of the liquid medium, the LSPC variants have process-specific characteristics, mainly classified by the product but also by the starting material. LAL, LFL
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Published 05 Jun 2024

Electron-induced deposition using Fe(CO)4MA and Fe(CO)5 – effect of MA ligand and process conditions

  • Hannah Boeckers,
  • Atul Chaudhary,
  • Petra Martinović,
  • Amy V. Walker,
  • Lisa McElwee-White and
  • Petra Swiderek

Beilstein J. Nanotechnol. 2024, 15, 500–516, doi:10.3762/bjnano.15.45

Graphical Abstract
  • combination with contributions of AG likely leads to aggregation and, thus, to a non-homogeneous thickness. In the extreme case that each aggregate has a thickness that exceeds the escape depth of the TaNNN Auger electrons (referred to herein as scenario B), the attenuation of the TaNNN signal would rather
  • ascribed to contributions of AG on the prior deposit (see also section Evaluation of deposit growth from AES data). The same conclusion can also be derived within scenario B, where the decrease of the TaNNN signal relates to an increasing area covered by Fe-containing aggregates. We recall that aggregation
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Published 08 May 2024

Potential of a deep eutectic solvent in silver nanoparticle fabrication for antibiotic residue detection

  • Le Hong Tho,
  • Bui Xuan Khuyen,
  • Ngoc Xuan Dat Mai and
  • Nhu Hoa Thi Tran

Beilstein J. Nanotechnol. 2024, 15, 426–434, doi:10.3762/bjnano.15.38

Graphical Abstract
  • the NPs as well as a high aggregation state (Figure 3A). This is because of the high viscosity of the DES, which directly affected the stirring and yielded nonspherical NP shapes. The aggregated Ag NPs are supported by pure DES in which oxygen and hydrogen atoms of ᴅ-glucose, urea, and glycerol tend
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Published 16 Apr 2024

Nanomedicines against Chagas disease: a critical review

  • Maria Jose Morilla,
  • Kajal Ghosal and
  • Eder Lilia Romero

Beilstein J. Nanotechnol. 2024, 15, 333–349, doi:10.3762/bjnano.15.30

Graphical Abstract
  • , nanomedicines are highly susceptible to aggregation, hygroscopicity, contamination, phase transition, amorphous-to-crystalline transitions, and degradation. It is critical to maintain batch-to-batch reproducibility (in terms of mean size, polydispersity, ζ-potential, and drug loading) not only during large
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Published 27 Mar 2024
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  • stability based on the aggregation phenomenon. This is well observed in MeOx NPs, where an increase in the oxidation number (χox) decreases the zeta potential. In WO3 NPs, the χox value is 6 and the zeta potential value is −23 mV; for NiO NPs, the χox value is 2, and the zeta potential value is 34.4 mV. The
  • hydroxyl radicals, resulting in oxidative damage to proteins. Moreover, they can bind non-specifically to amino acid residues and replace existing metal ions at active sites of enzymes, leading to abnormal protein folding. Protein aggregation diseases are a type of neurodegenerative diseases that occur
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Published 12 Mar 2024

New application of bimetallic Ag/Pt nanoplates in a colorimetric biosensor for specific detection of E. coli in water

  • Azam Bagheri Pebdeni,
  • Mohammad N. AL-Baiati and
  • Morteza Hosseini

Beilstein J. Nanotechnol. 2024, 15, 95–103, doi:10.3762/bjnano.15.9

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  • , and optical traits. The colorimetric method typically depends on the enzymatic properties, aggregation, and dispersion of these nanomaterials, which can be influenced by the presence of aptamers, antibodies, and other agents [4]. Among the various colorimetric test techniques, the enzymatic conversion
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Published 17 Jan 2024

Fluorescent bioinspired albumin/polydopamine nanoparticles and their interactions with Escherichia coli cells

  • Eloïse Equy,
  • Jordana Hirtzel,
  • Sophie Hellé,
  • Béatrice Heurtault,
  • Eric Mathieu,
  • Morgane Rabineau,
  • Vincent Ball and
  • Lydie Ploux

Beilstein J. Nanotechnol. 2023, 14, 1208–1224, doi:10.3762/bjnano.14.100

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  • , the high ionic strength of 150 mM NaCl decreased long-range effect and intensity of electrostatic interactions compared to the other solvents, thus favoring other types of interactions (such as attractive van der Waals interactions) and, therefore, aggregation. Second, the increase in salt
  • increased for both BSA/DA ratios of 3 and 10 after dialysis and freeze-drying (22% and 18%, respectively) (Supporting Information File 1, Figure S1e). During water evaporation, NPs may have been brought closer, leading to the formation of irreversible interactions and slight aggregation. This only slight
  • simultaneous presence of a positive charge and two additional diethylamino groups in RhBITC, which are absent in FITC. These two additional chemical moieties may have induced some weak aggregation between the negatively charged RhBITC-BSA/PDA NPs, in contrast to FITC-BSA/PDA NPs. Ox-BSA/PDA NPs were produced
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Published 22 Dec 2023

Curcumin-loaded albumin submicron particles with potential as a cancer therapy: an in vitro study

  • Nittiya Suwannasom,
  • Netsai Sriaksorn,
  • Chutamas Thepmalee,
  • Krissana Khoothiam,
  • Ausanai Prapan,
  • Hans Bäumler and
  • Chonthida Thephinlap

Beilstein J. Nanotechnol. 2023, 14, 1127–1140, doi:10.3762/bjnano.14.93

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  • mixed with 20 mL of 0.25 M Na2CO3 under constant vigorous stirring for 30 s at room temperature (RT). HSA solution (0.1%) was subsequently added to the mixture under stirring for 5 min to avoid particle aggregation. The obtained particle suspension was separated by centrifugation (6,000g for 3 min
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Published 21 Nov 2023

Sulfur nanocomposites with insecticidal effect for the control of Bactericera cockerelli

  • Lany S. Araujo-Yépez,
  • Juan O. Tigrero-Salas,
  • Vicente A. Delgado-Rodríguez,
  • Vladimir A. Aguirre-Yela and
  • Josué N. Villota-Méndez

Beilstein J. Nanotechnol. 2023, 14, 1106–1115, doi:10.3762/bjnano.14.91

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  • processes that involve classical nucleation, aggregation, and/or Ostwald ripening [38]. Figure 6 shows a STEM micrograph of the nanomicellar structure of a rosemary NCMP composed of two immiscible phases, that is, (a) the aqueous phase formed by the sulfur nanoparticles and (b) the oily phase formed by
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Published 17 Nov 2023

Recognition mechanisms of hemoglobin particles by monocytes – CD163 may just be one

  • Jonathan-Gabriel Nimz,
  • Pichayut Rerkshanandana,
  • Chiraphat Kloypan,
  • Ulrich Kalus,
  • Saranya Chaiwaree,
  • Axel Pruß,
  • Radostina Georgieva,
  • Yu Xiong and
  • Hans Bäumler

Beilstein J. Nanotechnol. 2023, 14, 1028–1040, doi:10.3762/bjnano.14.85

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  • a washing solution of 0.9% NaCl containing 0.2% HSA, particles were resuspended in 0.9% NaCl, checked via light microscopy for aggregation, and stored at 4 °C. Particle characterization To ensure that the subsequent experiments would be carried out on particles that also met the quality requirements
  • showed no aggregation within the particle suspension. Exclusion of confounders, indirect phagocytosis test HbMPs showed a low autofluorescence in the FITC channel in FACS analysis, which did not influence the fluorescence of DAPI in the PI channel. Whole blood (wb) generated a very low FITC signal as
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Published 19 Oct 2023

Exploring internal structures and properties of terpolymer fibers via real-space characterizations

  • Michael R. Roenbeck and
  • Kenneth E. Strawhecker

Beilstein J. Nanotechnol. 2023, 14, 1004–1017, doi:10.3762/bjnano.14.83

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  • single peak, but rather an aggregation of many individual peaks [3]. Ferreira et al. made similar observations from XRD and concluded that this broad peak reflected an “ordered but not crystalline” fiber structure [6]. In addition, analytical modeling of XRD spectra suggested that the three principal
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Published 05 Oct 2023

Nanoarchitectonics of photothermal materials to enhance the sensitivity of lateral flow assays

  • Elangovan Sarathkumar,
  • Rajasekharan S. Anjana and
  • Ramapurath S. Jayasree

Beilstein J. Nanotechnol. 2023, 14, 988–1003, doi:10.3762/bjnano.14.82

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  • the aggregation pattern of nanomaterials, and extrinsic factors, including surrounding medium, medium viscosity, and concentration of the nanomaterial. Most often, nanomaterials with complex three-dimensional structures have better optical and physicochemical properties for the use in colorimetry
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Published 04 Oct 2023
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