Recent progress on field-effect transistor-based biosensors: device perspective

• Billel Smaani,
• Fares Nafa,
• Mohamed Salah Benlatrech,
• Ismahan Mahdi,
• Hamza Akroum,
• Mohamed walid Azizi,
• Khaled Harrar and
• Sayan Kanungo

Beilstein J. Nanotechnol. 2024, 15, 977–994, doi:10.3762/bjnano.15.80

• to detect a wide range of biomolecules, such as proteins, DNA, and antibodies. This article presents a comprehensive review of advancements in the architectures of FET-based biosensors aiming to enhance device performance in terms of sensitivity, detection time, and selectivity. The review

• [27][28], surface-enhanced Raman spectroscopy [29][30], microfluidic-coupled biochip [31], electrochemical [32], and field-effect transistor (FET)-based biosensors [33]. Biosensors offer several distinct benefits for virus recognition, including higher selectivity through improved target receptors and

• -end biosensing parts are made using gold electrode material and manufactured by a lithography process, liftoff technique, and metal evaporation process. It has been indicated that the proposed EG FET-based biosensors exhibit super selectivity and high sensitivity for a reliable detection of uric acid

Identification of structural features of surface modifiers in engineered nanostructured metal oxides regarding cell uptake through ML-based classification

• Indrasis Dasgupta,
• Totan Das,
• Biplab Das and
• Shovanlal Gayen

Beilstein J. Nanotechnol. 2024, 15, 909–924, doi:10.3762/bjnano.15.75

• and U937. The primary objective is to find the structural fingerprints/features that govern cellular uptake selectivity for each cell line. The selective surface modifications of ENMOs could enhance the affinity of the nanoparticles for certain cell types while reducing the uptake by non-target cells

Facile synthesis of Fe-based metal–organic frameworks from Fe₂O₃ nanoparticles and their application for CO₂/N₂ separation

• Van Nhieu Le,
• Hoai Duc Tran,
• Minh Tien Nguyen,
• Hai Bang Truong,
• Toan Minh Pham and
• Jinsoo Kim

Beilstein J. Nanotechnol. 2024, 15, 897–908, doi:10.3762/bjnano.15.74

• resulting material, resulting in a high yield of 81% and an impressive BET surface area of 1365.4 m2·g−1. At 25 °C and 1 bar, M-100Fe@Fe2O3#1.80 showed a CO2 adsorption capacity of 1.10 mmol·g−1 and an IAST-predicted CO2/N2 selectivity of 18, outperforming conventional adsorbents in CO2/N2 separation

• . Importantly, this route opens a new approach to utilizing Fe2O3-based waste materials from the iron and steel industry in manufacturing Fe-based MIL-100 materials. Keywords: CO2/N2 separation; Fe2O3 nanoparticles; hydrothermal reaction; IAST-predicted CO2/N2 selectivity; MIL-100(Fe); Introduction Metal

• . Estimation of CO2/N2 selectivity via ideal adsorbed solution theory (IAST) The IAST is widely recognized as a predictive means to evaluate the adsorption selectivity of an adsorbent towards a gas mixture without experimental data for the gas mixture. Herein, a binary mixture of CO2 and N2 containing 10 vol

When nanomedicines meet tropical diseases

• Eder Lilia Romero,
• Katrien Van Bocxlaer and
• Fabio Rocha Formiga

Beilstein J. Nanotechnol. 2024, 15, 830–832, doi:10.3762/bjnano.15.69

• oxide nanoparticles (SPIONs) for treating cutaneous lesions caused by Leishmania amazonensis. The selectivity index for intracellular amastigotes was more than 240 times higher compared to that of current prescribed drugs to treat the disease, making SPIONs strong candidates for a new therapeutic

Synthesis of silver–palladium Janus nanoparticles using co-sputtering of independent sources: experimental and theorical study

• Maria J. Martínez-Carreón,
• Francisco Solís-Pomar,
• Abel Fundora,
• Claudio D. Gutiérrez-Lazos,
• Sergio Mejía-Rosales,
• Hector N. Fernández-Escamilla,
• Jonathan Guerrero-Sánchez,
• Manuel F. Meléndrez and
• Eduardo Pérez-Tijerina

Beilstein J. Nanotechnol. 2024, 15, 808–816, doi:10.3762/bjnano.15.67

• under vacuum. AgPd nanoparticles also exhibit activity in the hydrogenation of acetylene and ethylene. Khan et al. [8] found that the addition of Ag to Pd supported on alumina suppresses the general hydrogenation activity, but it also increases the selectivity towards ethylene avoiding acetylene

Simultaneous electrochemical determination of uric acid and hypoxanthine at a TiO₂/graphene quantum dot-modified electrode

• Vu Ngoc Hoang,
• Dang Thi Ngoc Hoa,
• Nguyen Quang Man,
• Le Vu Truong Son,
• Le Van Thanh Son,
• Vo Thang Nguyen,
• Le Thi Hong Phong,
• Ly Hoang Diem,
• Kieu Chan Ly,
• Ho Sy Thang and
• Dinh Quang Khieu

Beilstein J. Nanotechnol. 2024, 15, 719–732, doi:10.3762/bjnano.15.60

• URI shifts positively as the pulse amplitude increases. This behavior might reduce the selectivity of the analytical method. Therefore, a pulse amplitude of 0.08 V was chosen for further studies. Ustep in differential pulse anodic stripping voltammetry affects the potential scan rate and the stripping

• ) with LODHYP = 0.57 μM (Figure 8d) was found. These results indicate that the determination of URI in the presence of HYP and vice versa at the TiO2/GQDs-GCE can be achieved with acceptable selectivity and sensitivity. A comparison with previously reported data is shown in Table 1. It is noticed that

• stability of the (1:4)TiO2/QGDs-GCE (Figure 9d). In order to study the selectivity of the (1:4)TiO2/GQDs-modified electrode, common co-existing substances, namely, NH4Cl, KCl, Na2SO4, NH4NO3, CaCl2, ZnCl2, glucose (GLC), glutamic acid (GLA), urea (URE), ʟ-cysteine (LCY) and xanthine (XTE), have been added

On the additive artificial intelligence-based discovery of nanoparticle neurodegenerative disease drug delivery systems

• Shan He,
• Julen Segura Abarrategi,
• Harbil Bediaga,
• Sonia Arrasate and
• Humberto González-Díaz

Beilstein J. Nanotechnol. 2024, 15, 535–555, doi:10.3762/bjnano.15.47

• inadequate solubility, limited bioavailability, and inability to effectively penetrate the blood–brain barrier (BBB) [6]. Therefore, there is an urgent need to focus on the advancement of novel neurodegenerative disease drugs (NDDs) [7][8]. The major obstacle encountered by NDDs is the selectivity of the BBB

Electron-induced deposition using Fe(CO)₄MA and Fe(CO)₅ – effect of MA ligand and process conditions

• Hannah Boeckers,
• Atul Chaudhary,
• Petra Martinović,
• Amy V. Walker,
• Lisa McElwee-White and
• Petra Swiderek

Beilstein J. Nanotechnol. 2024, 15, 500–516, doi:10.3762/bjnano.15.45

• electron beam-induced surface activation (EBISA) [24][25], it can compromise spatial control by the electron beam and selectivity when aiming for 3D nanostructures [3][26]. Strategies to suppress autocatalytic deposit growth are thus desirable to devise FEBID processes with optimum performance [27

Potential of a deep eutectic solvent in silver nanoparticle fabrication for antibiotic residue detection

• Le Hong Tho,
• Bui Xuan Khuyen,
• Ngoc Xuan Dat Mai and
• Nhu Hoa Thi Tran

Beilstein J. Nanotechnol. 2024, 15, 426–434, doi:10.3762/bjnano.15.38

• NFT and SDZ, respectively. Besides, the linearity coefficients are extremely close to 1 in the range of 10−8 to 10−3 M of concentration, and the SERS substrate shows remarkable uniformity along with great selectivity. This powerful SERS performance indicates that DESs have tremendous potential in the

• [2], the ability of real-time measurements [3], extremely high sensitivity [4], remarkable selectivity [5], and tremendous versatility [4][6][7]. Many scholars have taken advantage of these properties in cancer diagnosis [8], detection of hazardous chemicals [9], tracing of microorganisms [7][10][11

• distribution indicates good uniformity, that is, satisfactory stability. These results can be explained by the LSPR of the rod-like Ag NPs synthesized in DES, which plays an important role in the high intensity [48] and the uniformity of the Ag NPs-DES coating proven in Figure 3B. SDZ detection and selectivity

Design, fabrication, and characterization of kinetic-inductive force sensors for scanning probe applications

• August K. Roos,
• Ermes Scarano,
• Elisabet K. Arvidsson,
• Erik Holmgren and
• David B. Haviland

Beilstein J. Nanotechnol. 2024, 15, 242–255, doi:10.3762/bjnano.15.23

• using a wet-etch in potassium hydroxide (KOH). The wet-etch has a high selectivity between silicon and silicon nitride, and KOH etches silicon with different rates in the ⟨100⟩ and ⟨111⟩ crystalline directions. With proper orientation of the cantilever mask to the crystalline axes of the wafer, one can

New application of bimetallic Ag/Pt nanoplates in a colorimetric biosensor for specific detection of E. coli in water

• Azam Bagheri Pebdeni,
• Mohammad N. AL-Baiati and
• Morteza Hosseini

Beilstein J. Nanotechnol. 2024, 15, 95–103, doi:10.3762/bjnano.15.9

• the capacity to do analysis for an extended period of time. Also, this aptasensor can function well on a paper-based platform and, as the cost of the paper is low, the production of this biosensor compared to many similar biosensors is lower. Evaluation of selectivity The selectivity of the Ag/Pt NPLs

• greater than that when E. coli was present (Supporting Information File 1, Figure S4). The NPL selectivity refers to the specificity of the applied aptamer toward the surface structures of the target. The aptamer boosted the NPL selectivity and specificity against E. coli, and it is not prone to adhering

Curcumin-loaded nanostructured systems for treatment of leishmaniasis: a review

• Douglas Dourado,
• Thayse Silva Medeiros,
• Éverton do Nascimento Alencar,
• Edijane Matos Sales and
• Fábio Rocha Formiga

Beilstein J. Nanotechnol. 2024, 15, 37–50, doi:10.3762/bjnano.15.4

• decrease in macrophage cytotoxicity of the nanoencapsulated molecule when compared to its free form. In addition, the uptake of these nanoparticles by macrophages was higher than that by fibroblasts, with an IC50 approximately two times lower than that of the free drug, and a selectivity index 20 times

• against resistant strains of Leishmania donovani, which resulted in a 15-fold improvement in drug activity when into NLC, with a selectivity index for the intracellular model in macrophages almost three times higher than that of the free drug. In vivo studies showed that the suppression of parasite load

• by macrophages, promoting an increase in antileishmanial efficacy, a decrease of toxicity, and, as a result, an increase in the selectivity index of these compounds. The same rationale is applied to the incorporation of curc in nanostructured systems, which will be discussed in the following topics

TEM sample preparation of lithographically patterned permalloy nanostructures on silicon nitride membranes

• Joshua Williams,
• Michael I. Faley,
• Joseph Vimal Vas,
• Peng-Han Lu and
• Rafal E. Dunin-Borkowski

Beilstein J. Nanotechnol. 2024, 15, 1–12, doi:10.3762/bjnano.15.1

• techniques, a one-time exposure is possible with the help of high accelerating voltage during electron beam exposure. In this process, rather than doing one resist deposition and exposure after another, the layer selectivity is controlled by the electron beam dose and the sensitivity of the two layers. Only

Spatial variations of conductivity of self-assembled monolayers of dodecanethiol on Au/mica and Au/Si substrates

• Julian Skolaut,
• Jędrzej Tepper,
• Federica Galli,
• Wulf Wulfhekel and
• Jan M. van Ruitenbeek

Beilstein J. Nanotechnol. 2023, 14, 1169–1177, doi:10.3762/bjnano.14.97

• , including many studies performed recently on SAMs of helical oligopeptides studying chiral-induced spin-selectivity [12][13][14][15]. Here, we re-examine the information that is obtained from CAFM, and we demonstrate that the nature of the metallic substrate is of critical importance. The lateral variation

Spatial mapping of photovoltage and light-induced displacement of on-chip coupled piezo/photodiodes by Kelvin probe force microscopy under modulated illumination

• Zeinab Eftekhari,
• Nasim Rezaei,
• Hidde Stokkel,
• Jian-Yao Zheng,
• Andrea Cerreta,
• Ilka Hermes,
• Minh Nguyen,
• Guus Rijnders and
• Rebecca Saive

Beilstein J. Nanotechnol. 2023, 14, 1059–1067, doi:10.3762/bjnano.14.87

• . It can also be related to the backside etching of the substrate with poor selectivity, which can form undercuts, causing thinner edges than the central part of the membrane and restricting the movement of the membrane on top. From the simulations, we expected that the maximum displacement increases

Metal-organic framework-based nanomaterials for CO₂ storage: A review

• Ha Huu Do,
• Iqra Rabani and
• Hai Bang Truong

Beilstein J. Nanotechnol. 2023, 14, 964–970, doi:10.3762/bjnano.14.79

• gas storage. For instance, Zhang et al. used ethylenediamine to functionalize ZIF-8, resulting in enhanced CO2 adsorption and selectivity [36]. A benefit of this approach is that the surface area was improved (nearly 40%), while ED-ZIF-8 yielded a two-fold higher amount of adsorbed CO2 than pure ZIF-8

• global warming. However, despite the considerable research efforts dedicated to MOFs in the context of CO2 adsorption, certain drawbacks still need to be addressed. Primarily, a large number of MOFs have poor CO2 selectivity in the presence of water and acid gases. These species have higher polarities

Antibody-conjugated nanoparticles for target-specific drug delivery of chemotherapeutics

• Mamta Kumari,
• Amitabha Acharya and
• Praveen Thaggikuppe Krishnamurthy

Beilstein J. Nanotechnol. 2023, 14, 912–926, doi:10.3762/bjnano.14.75

• chemotherapeutics specifically to the targeted cancer cells. ACNPs combine the benefits of NPs and mAbs to provide high drug loads at the tumor site with better selectivity and delivery efficiency. The mAbs on the NP surfaces recognize their specific receptors expressed on the target cells and release the

• receptors and, therefore, provide more selectivity for diseased cells. The available evidence suggest that NPs increase the targeting efficacy by providing multiple copies of targeting ligand on the NP surface. This enhances multiple bindings between receptor–ligand pairs [74][75]. Hence, the multivalent

• lack of tumor specificity and selectivity, antibody selection issues, immune reactions against ACNPs, stability of ACNPs, heterogeneity of tumors, regulatory approvals, scale-up and production, and cost considerations. Advantages of antibody-conjugated NPs. Schematic representation of (a) an antibody

Ni, Co, Zn, and Cu metal-organic framework-based nanomaterials for electrochemical reduction of CO₂: A review

• Ha Huu Do and
• Hai Bang Truong

Beilstein J. Nanotechnol. 2023, 14, 904–911, doi:10.3762/bjnano.14.74

• . Subsequently, multiple electron transfers occur, leading to the generation of diverse products such as ethanol, methanol, and methane [5][6][7]. Therefore, to reduce the activation energy and to improve selectivity, the meticulous consideration of catalysts becomes imperative [8][9][10][11][12][13][14][15][16

• ]. The first work on electrocatalytic CO2 reduction was published in 1870 using a Zn material to produce HCOOH [17][18]. Subsequent investigations have yielded numerous studies focusing on the development of electrocatalysts for CO2RR. In 1994, Hori et al. highlighted that the selectivity of products

Green SPIONs as a novel highly selective treatment for leishmaniasis: an in vitro study against Leishmania amazonensis intracellular amastigotes

• Brunno R. F. Verçoza,
• Robson R. Bernardo,
• Luiz Augusto S. de Oliveira and
• Juliany C. F. Rodrigues

Beilstein J. Nanotechnol. 2023, 14, 893–903, doi:10.3762/bjnano.14.73

• effects on cell proliferation, infectivity percentage, and ultrastructure. SPIONs were internalized by both parasite stages, randomly distributed in the cytosol and located mainly in membrane-bound compartments. The selectivity index for intracellular amastigotes was more than 240 times higher compared to

• for L. amazonensis intracellular amastigotes (Table 1), presenting values significantly higher when compared with other compounds and drugs used to treat Leishmania sp. (Table 2) [22][23][24][25][26][27]. These data indicate a high selectivity index for SPIONs compared with current treatments

• of drug conjugation with magnetic nanoparticles for treating leishmaniasis. Conclusion The use of SPIONs synthesized with coconut water to treat macrophages infected with Leishmania amazonensis intracellular amastigotes revealed a significant anti-Leishmania effect with a selectivity index more than

Current-induced mechanical torque in chiral molecular rotors

• Richard Korytár and
• Ferdinand Evers

Beilstein J. Nanotechnol. 2023, 14, 711–721, doi:10.3762/bjnano.14.57

• crossover between both regimes. To exemplify our results, we employ a helical geometry. Helical molecular wires have sparked a lot of attention because of reports of spin-selective transport [16][17][18]. This phenomenon falls under the umbrella term “chirality-induced spin selectivity (CISS)”. The full

A graphene quantum dots–glassy carbon electrode-based electrochemical sensor for monitoring malathion

• Sanju Tanwar,
• Aditi Sharma and
• Dhirendra Mathur

Beilstein J. Nanotechnol. 2023, 14, 701–710, doi:10.3762/bjnano.14.56

• working electrode has an increased surface area to volume ratio due to the small size of GQDs. In addition, the different functional groups present on the GQDs surfaces provide additional active sites, which increase sensitivity and lower the limit of detection. Interference study The selectivity of the

• to 30 µM, a linear relationship was observed between the peak current and the malathion concentration. A detection limit of 0.62 nM was determined, and an interference study showed that the developed electrochemical sensor is selective for malathion. The sensor’s selectivity for malathion can be

• attributed to its surface composition of different functional groups providing specific sites for pesticide molecules. These results demonstrate that the GQDs/GCE electrochemical sensor is capable of detecting malathion over a wide linear range with low detection limits and high selectivity. The graphene

Metal-organic framework-based nanomaterials as opto-electrochemical sensors for the detection of antibiotics and hormones: A review

• Akeem Adeyemi Oladipo,
• Saba Derakhshan Oskouei and
• Mustafa Gazi

Beilstein J. Nanotechnol. 2023, 14, 631–673, doi:10.3762/bjnano.14.52

• spectrometry (LC–MS), high-performance liquid chromatography (HPLC), and gas chromatography coupled with mass spectrometry (GC–MS) have demonstrated greater selectivity and lower variability when compared to immunoassays for the measurement of antibiotics and steroid hormones in various complex samples [22][23

• as the necessity for technical experts with the necessary training, the limited selectivity and reusability of substrates, and the degradation of substrates with time, which reduces the signal. Several portable electrochemical and optical (chemiluminescence, fluorescence, and electrochemiluminescence

• and challenges It is crucial to assess the performance of sensors during development using standard metrics such as selectivity, sensitivity, the limit of detection (LOD), and response time. Selectivity refers to a sensor’s capacity to respond to a narrow range of target analytes while resisting

Observation of multiple bulk bound states in the continuum modes in a photonic crystal cavity

• Rui Chen,
• Yi Zheng,
• Xingyu Huang,
• Qiaoling Lin,
• Chaochao Ye,
• Meng Xiong,
• Martijn Wubs,
• Yungui Ma,
• Minhao Pu and
• Sanshui Xiao

Beilstein J. Nanotechnol. 2023, 14, 544–551, doi:10.3762/bjnano.14.45

• simulations. Our findings have potential applications regarding the mode selectivity in BIC devices to manipulate the lasing mode in photonic-crystal surface-emitting lasers or the radiation pattern in nonlinear optics. Keywords: bound states in the continuum; bulk modes analysis; photonic crystal

• with the same polarization were analyzed. The existence of multiple bulk modes in our confined BIC cavities and the strong position dependence of the excitation efficiency of those modes provide an efficient way to control radiation pattern and mode selectivity in the BIC devices. Design of the unit

Molecular nanoarchitectonics: unification of nanotechnology and molecular/materials science

• Katsuhiko Ariga

Beilstein J. Nanotechnol. 2023, 14, 434–453, doi:10.3762/bjnano.14.35

• induce site-specific organic synthesis and alter selectivity, as seen in the example of local probe chemistry. Indeed, it is now possible to pick up specific substrate molecules and make them react at desired molecular sites. This could be the starting point for assembling functional materials from the

Plasmonic nanotechnology for photothermal applications – an evaluation

• A. R. Indhu,
• L. Keerthana and
• Gnanaprakash Dharmalingam

Beilstein J. Nanotechnol. 2023, 14, 380–419, doi:10.3762/bjnano.14.33

• that have been discussed in preceding sections [85]. PPT heating has subwavelength spatial selectivity, implying that changes to absorption and, hence, heating can be affected by means of changing the lasing power density and/or the wavelength. Indeed, NP morphologies have even been shown to be