Search results

Search for "dose" in Full Text gives 296 result(s) in Beilstein Journal of Nanotechnology. Showing first 200.

Single-step process to improve the mechanical properties of carbon nanotube yarn

  • Maria Cecilia Evora,
  • Xinyi Lu,
  • Nitilaksha Hiremath,
  • Nam-Goo Kang,
  • Kunlun Hong,
  • Roberto Uribe,
  • Gajanan Bhat and
  • Jimmy Mays

Beilstein J. Nanotechnol. 2018, 9, 545–554, doi:10.3762/bjnano.9.52

Graphical Abstract
  • , Acros Organics, 99+%). All chemical reagents were used as received. The irradiation process was carried out in an industrial accelerator operated by NEO Beam – Mercury Plastics, Inc – Middlefield-OH, 3.8 MeV beam energy, pulse current 38.3 mA, 27 kGy/pass with dose rate of 5 kGy/s. Sample preparation A
  • a dose of 27 kGy. The low dose of 27 kGy was chosen for this preliminary investigation because only functionalization on the MWNT powder surface was desired. The aim of this preliminary study was to verify the conversion of AN to PAN on the MWNT powder surface under e-beam irradiation. An aqueous
  • electronic band structure of the graphitic material. There was a decrease of the G′ peak FWHM from 117.51 cm−1 (untreated sample) to 109.51 cm−1 (treated with 80% AN and irradiated with a dose of 108 kGy) and 105 cm−1 (treated with 80% AA and irradiated with a dose of 108 kGy) (Figure 3). This happens
PDF
Album
Full Research Paper
Published 13 Feb 2018

Gas-assisted silver deposition with a focused electron beam

  • Luisa Berger,
  • Katarzyna Madajska,
  • Iwona B. Szymanska,
  • Katja Höflich,
  • Mikhail N. Polyakov,
  • Jakub Jurczyk,
  • Carlos Guerra-Nuñez and
  • Ivo Utke

Beilstein J. Nanotechnol. 2018, 9, 224–232, doi:10.3762/bjnano.9.24

Graphical Abstract
  • , silver crystal growth presents a strong dependency on electron dose and precursor refreshment. Keywords: focused electron beam induced deposition; low volatility precursor; silver; Introduction The fabrication of defined patterns in the nanometer regime demands techniques with high lateral resolution
  • irradiates it again, thus the FEBID can continue with fresh adsorbates and less co-deposition of carbon. For further studies, box deposits were written with the same electron dose of 7.44 nC/µm2 but different dwell and refreshment times. On first sight it is visible that for short refreshment times as in
  • evidence that the crystals seen in the scanning electron micrographs (Figure 1) are made of silver. Figure 3a depicts a line written on a carbon membrane of a TEM grid in our SEM with 25 kV and 0.5 nA and an electron dose of 0.79 pC/µm. Figure 3b displays a bright field scanning transmission electron
PDF
Album
Supp Info
Full Research Paper
Published 19 Jan 2018

Comparative study of post-growth annealing of Cu(hfac)2, Co2(CO)8 and Me2Au(acac) metal precursors deposited by FEBID

  • Marcos V. Puydinger dos Santos,
  • Aleksandra Szkudlarek,
  • Artur Rydosz,
  • Carlos Guerra-Nuñez,
  • Fanny Béron,
  • Kleber R. Pirota,
  • Stanislav Moshkalev,
  • José Alexandre Diniz and
  • Ivo Utke

Beilstein J. Nanotechnol. 2018, 9, 91–101, doi:10.3762/bjnano.9.11

Graphical Abstract
  • here we studied 50 nm thick thin films while the previous material was much thicker and received a higher dose during post-growth irradiation of the already deposited underlying material. The same mechanism could also be responsible for the lower copper content found in the present study. Raman
PDF
Album
Supp Info
Full Research Paper
Published 09 Jan 2018

Response under low-energy electron irradiation of a thin film of a potential copper precursor for focused electron beam induced deposition (FEBID)

  • Leo Sala,
  • Iwona B. Szymańska,
  • Céline Dablemont,
  • Anne Lafosse and
  • Lionel Amiaud

Beilstein J. Nanotechnol. 2018, 9, 57–65, doi:10.3762/bjnano.9.8

Graphical Abstract
  • for 210 min. Regular off-beam measurements are taken to remove the background contribution from the desorption signal. The evolution with the cumulated dose of the CF3 signal, normalized to transmitted current, is plotted in Figure 4. The signal is decreasing with time as the available quantities on
  • corresponding colour. Evolution of CF3 neutral fragment detection with the cumulated dose (fluence) under irradiation at 1.5 eV. Squares: measurement, line: adjusted model. HREELS vibrational signature attributions. Acknowledgements This work was conducted within the framework of the COST action CM1301 (CELINA
PDF
Album
Full Research Paper
Published 05 Jan 2018

Hyperthermic intracavitary nanoaerosol therapy (HINAT) as an improved approach for pressurised intraperitoneal aerosol chemotherapy (PIPAC): Technical description, experimental validation and first proof of concept

  • Daniel Göhler,
  • Stephan Große,
  • Alexander Bellendorf,
  • Thomas Albert Falkenstein,
  • Mehdi Ouaissi,
  • Jürgen Zieren,
  • Michael Stintz and
  • Urs Giger-Pabst

Beilstein J. Nanotechnol. 2017, 8, 2729–2740, doi:10.3762/bjnano.8.272

Graphical Abstract
  • 1.4 bar that led to an effective dose of the 99mTc pertechnetate-containing solution of 0.28 mL. PIPAC-MIP was performed at a volumetric flow rate of 30 mL/min for 5 min that led to a dose of 150 mL. Short after 99mTc pertechnetate exposure, scintigraphic analyses (i.e., planar scintigraphy as well as
  • projections with a resolution of 128 × 128 px were recorded with an acquisition time of 8 s per projection. Anterior (i.e., LDR = left–dorsal–right) as well posterior (i.e., RVL = right–ventral–left) planar images were acquired with an acquisition time of 3 min per position. Finally, a low-dose computer
  • doxorubicin dose of 0.88 mL (i.e., 1.76 mg doxorubicin hydrochloride). PIPAC-MIP was performed with diluted doxorubicin (1 mL doxorubicin in 50 mL aqueous 0.9 wt % sodium chloride solution) at a volumetric flow rate of 30 mL/min for 100 s that led to an effective doxorubicin dose of 2.9 mL (i.e., 5.8 mg
PDF
Album
Full Research Paper
Published 18 Dec 2017

Localized growth of carbon nanotubes via lithographic fabrication of metallic deposits

  • Fan Tu,
  • Martin Drost,
  • Imre Szenti,
  • Janos Kiss,
  • Zoltan Kónya and
  • Hubertus Marbach

Beilstein J. Nanotechnol. 2017, 8, 2592–2605, doi:10.3762/bjnano.8.260

Graphical Abstract
  • contain high amounts of carbon as contamination. For example, Sharma et al. [20] presented the possibility to control the deposited particle size by varying the EBID parameters (i.e., electron dose and beam current) but no further CNTs were shown to grow on these as-deposited Fe-containing nanoparticles
  • catalysts to synthesize well-defined CNTs with controllable morphology via CVD. The influence of the chemical composition and, in particular, of the fabrication parameters (i.e., electron dose and AG time) of Fe deposits were investigated with respect to their suitability and properties as seeds for
  • subsequent AG (≈60 min autocatalytic growth time) in our UHV instrument. Here, the EBID process was performed as a point irradiation, that is, the electron beam rests at a fixed position for a certain amount of time and thus provides a controlled local electron dose. The enlargement of the deposits with
PDF
Album
Supp Info
Full Research Paper
Published 05 Dec 2017

Amplified cross-linking efficiency of self-assembled monolayers through targeted dissociative electron attachment for the production of carbon nanomembranes

  • Sascha Koch,
  • Christopher D. Kaiser,
  • Paul Penner,
  • Michael Barclay,
  • Lena Frommeyer,
  • Daniel Emmrich,
  • Patrick Stohmann,
  • Tarek Abu-Husein,
  • Andreas Terfort,
  • D. Howard Fairbrother,
  • Oddur Ingólfsson and
  • Armin Gölzhäuser

Beilstein J. Nanotechnol. 2017, 8, 2562–2571, doi:10.3762/bjnano.8.256

Graphical Abstract
  • spectroscopy (XPS), to determine whether the high relative DEA cross section for iodide loss from 2-I-BPT as compared to 2-Br-BP and 2-Cl-BP is reflected in the cross-linking efficiency of SAMs made from these materials. Such sensitization could reduce the electron dose needed for the cross-linking process and
  • ) verified the existence of a mechanically stable CNM created from 2-I-BPT after exposure to an electron dose as low as 1.8 mC/cm2. In contrast, SAMs made from BPT, 2-Cl-BPT and 2-Br-BPT did not form stable CNMs after a significantly higher electron dose of 9 mC/cm2. Keywords: 2D materials; carbon
  • determination of the required dose for the respective CNM formation also by directly testing the mechanical strength and microscope images of the cross-linked SAMs. Figure 2a shows the XP spectra of the respective halogen atoms of 2-Cl-BPT, 2-Br-BPT and 2-I-BPT, recorded for nine different stages of irradiation
PDF
Album
Full Research Paper
Published 30 Nov 2017

Direct writing of gold nanostructures with an electron beam: On the way to pure nanostructures by combining optimized deposition with oxygen-plasma treatment

  • Domagoj Belić,
  • Mostafa M. Shawrav,
  • Emmerich Bertagnolli and
  • Heinz D. Wanzenboeck

Beilstein J. Nanotechnol. 2017, 8, 2530–2543, doi:10.3762/bjnano.8.253

Graphical Abstract
  • atom %, depending on the sustained electron beam dose. As a second step, oxygen-plasma treatment is established to further enhance the Au content in the structures, while preserving their morphology to a high degree. This two-step process represents a simple, feasible and high-throughput method for
  • samples were produced using the same HT and I values, the electron dose that the material sustained during deposition was approximately two times higher in the case of planar structure (2.3 × 10−7 C·μm−2 vs ≈1 × 10-7 C·μm−2). It was the first clear evidence that a change of electron beam parameters could
  • , the full experimental parameter space of a typical FEBID system is multidimensional – it encompasses electron beam parameters (such as acceleration voltage, i.e., high tension, electron beam current, electron dose, i.e., deposition time), precursor parameters (such as precursor type, flux, and
PDF
Album
Supp Info
Full Research Paper
Published 29 Nov 2017

Comparing postdeposition reactions of electrons and radicals with Pt nanostructures created by focused electron beam induced deposition

  • Julie A. Spencer,
  • Michael Barclay,
  • Miranda J. Gallagher,
  • Robert Winkler,
  • Ilyas Unlu,
  • Yung-Chien Wu,
  • Harald Plank,
  • Lisa McElwee-White and
  • D. Howard Fairbrother

Beilstein J. Nanotechnol. 2017, 8, 2410–2424, doi:10.3762/bjnano.8.240

Graphical Abstract
  • ) and was invariant to further increases in electron dose. In related studies, EDS of PtCl2 deposits exposed to 20 h of electron irradiation in the AES revealed only a small decrease (≈5%) in the Cl EDS signal (see Figure 1d). Similarly, electron beam irradiation of PtCl2 deposits in the SEM for 2 h at
  • , under precursor limited deposition conditions. In such a scenario, each PtCl2 moiety deposited at the surface of the growing nanostructure could be exposed to a sufficiently large electron dose to effect Cl loss. Atomic hydrogen (AH) As shown in Figures 2–5, exposure of PtCl2 deposits to AH using the
PDF
Album
Supp Info
Full Research Paper
Published 15 Nov 2017

Involvement of two uptake mechanisms of gold and iron oxide nanoparticles in a co-exposure scenario using mouse macrophages

  • Dimitri Vanhecke,
  • Dagmar A. Kuhn,
  • Dorleta Jimenez de Aberasturi,
  • Sandor Balog,
  • Ana Milosevic,
  • Dominic Urban,
  • Diana Peckys,
  • Niels de Jonge,
  • Wolfgang J. Parak,
  • Alke Petri-Fink and
  • Barbara Rothen-Rutishauser

Beilstein J. Nanotechnol. 2017, 8, 2396–2409, doi:10.3762/bjnano.8.239

Graphical Abstract
  • monitored by dynamic light scattering and the dose deposited onto the cell surface was determined by a modelling approach. The murine macrophage cell line J774A.1 was then used to study uptake and intracellular fate by means of laser scanning microscopy (LSM), environmental scanning electron microscopy
  • characterization. Given that the particles were polydisperse and were functionalized with a polymer, the dose delivered near the cell was estimated by approaches reported elsewhere, taking into account the geometrical parameters of the cell culture wells, such as overall fluid volume and well diameter [28][29
  • NPs adhere to it, and the delivered dose is expressed as the fraction of the administered dose (Figure 1). AuNPs deposited faster than FeOxNPs, and hence a higher fraction of AuNPs was in contact with the cells throughout the experiment. After 5 min, more than 5% of the administered dose arrived at
PDF
Album
Supp Info
Full Research Paper
Published 14 Nov 2017

Bi-layer sandwich film for antibacterial catheters

  • Gerhard Franz,
  • Florian Schamberger,
  • Hamideh Heidari Zare,
  • Sara Felicitas Bröskamp and
  • Dieter Jocham

Beilstein J. Nanotechnol. 2017, 8, 1982–2001, doi:10.3762/bjnano.8.199

Graphical Abstract
  • drug. However, its toxic behavior is also well known. Unfortunately, systematic investigations referring to toxicity and long-term exposition are rare. In 1996, the U.S. Environmental Protection Agency (EPA) published values for the long-term oral reference dose (RfD) [20][21]. These values are based
PDF
Album
Full Research Paper
Published 22 Sep 2017

Application of visible-light photosensitization to form alkyl-radical-derived thin films on gold

  • Rashanique D. Quarels,
  • Xianglin Zhai,
  • Neepa Kuruppu,
  • Jenny K. Hedlund,
  • Ashley A. Ellsworth,
  • Amy V. Walker,
  • Jayne C. Garno and
  • Justin R. Ragains

Beilstein J. Nanotechnol. 2017, 8, 1863–1877, doi:10.3762/bjnano.8.187

Graphical Abstract
  • × 10−9 mbar. The primary Bi+ ions had a kinetic energy of 25 keV, were contained within a ≈ 100 nm diameter probe beam, and were rastered over a (100 × 100) μm2 area. All spectra were obtained in the static regime using a total ion dose of less than 1010 ions·cm−2. The secondary ions were extracted
PDF
Album
Supp Info
Full Research Paper
Published 06 Sep 2017

Synthesis and functionalization of NaGdF4:Yb,Er@NaGdF4 core–shell nanoparticles for possible application as multimodal contrast agents

  • Dovile Baziulyte-Paulaviciene,
  • Vitalijus Karabanovas,
  • Marius Stasys,
  • Greta Jarockyte,
  • Vilius Poderys,
  • Simas Sakirzanovas and
  • Ricardas Rotomskis

Beilstein J. Nanotechnol. 2017, 8, 1815–1824, doi:10.3762/bjnano.8.183

Graphical Abstract
  • . Our results showed that Tween 80-coated UCNPs exhibited low cytotoxicity even at a high-dose concentration. Results and Discussion The SEM images of the NaGdF4:Yb,Er core and NaGdF4:Yb,Er@NaGdF4 core–shell nanoparticles are shown in Figure 1. Core nanoparticles are monodisperse, and have a spherical
PDF
Album
Supp Info
Full Research Paper
Published 01 Sep 2017

A nanocomplex of C60 fullerene with cisplatin: design, characterization and toxicity

  • Svitlana Prylutska,
  • Svitlana Politenkova,
  • Kateryna Afanasieva,
  • Volodymyr Korolovych,
  • Kateryna Bogutska,
  • Andriy Sivolob,
  • Larysa Skivka,
  • Maxim Evstigneev,
  • Viktor Kostjukov,
  • Yuriy Prylutskyy and
  • Uwe Ritter

Beilstein J. Nanotechnol. 2017, 8, 1494–1501, doi:10.3762/bjnano.8.149

Graphical Abstract
  • % Tween 80 aqueous solution no positive mutagenic response was observed up to the dose of 1 mg/plate with any tester strain in the bacterial genotoxicity tests in vitro and in vivo [28]. The aqueous suspension of C60 fullerenes caused positive responses in two bacterial genotoxicity tests, namely the
  • concentration in biomedium, dose administration, type of cells and time of exposure. Since the biological action of C60 fullerene significantly differs from the action of traditional drugs by the mechanism of penetration inside cells and biodistribution [23][24][25][32][33][34][35], the conjugation of С60
PDF
Album
Full Research Paper
Published 20 Jul 2017

Development of polycationic amphiphilic cyclodextrin nanoparticles for anticancer drug delivery

  • Gamze Varan,
  • Juan M. Benito,
  • Carmen Ortiz Mellet and
  • Erem Bilensoy

Beilstein J. Nanotechnol. 2017, 8, 1457–1468, doi:10.3762/bjnano.8.145

Graphical Abstract
  • of chemotherapy with PCX. A promising step was taken with the FDA approval of albumin nanoparticle bound PCX (Abraxane®) in 2005 for breast cancer treatment with a significantly lower dose [8]. This was considered a breakthrough in PCX formulation development as it avoided the use of solubilizers
  • , delivering the drug bound to the nanocarriers in a considerably lower dose to target tissue. Cyclodextrins (CDs) are cyclic oligosaccharides obtained through enzymatic degradation of starch. The most frequently used CDs in the pharmaceutical field are α-CD, β-CD and γ-CD having 6, 7 and 8 subunits
  • presence of PF68 in CD nanoparticle formulations on cytotoxicity on L929, a healthy mouse fibroblast cell line. According to these results, it was suggested that PF68 has no significant effect on size and drug loading capacity of nanoparticles but dose-dependent toxicity could occur on L929 fibroblast
PDF
Album
Full Research Paper
Published 13 Jul 2017

Cationic PEGylated polycaprolactone nanoparticles carrying post-operation docetaxel for glioma treatment

  • Cem Varan and
  • Erem Bilensoy

Beilstein J. Nanotechnol. 2017, 8, 1446–1456, doi:10.3762/bjnano.8.144

Graphical Abstract
  • that all formulations are safe for in vivo application, regardless of dose or time. Anticancer efficacy of docetaxel-loaded nanoparticles The anticancer efficacy of drug-loaded nanoparticle dispersions were determined on rat glioma cell line RG2. As seen in Figure 7, anticancer efficiency is enhanced
  • prolonged by up to 2 days due to the implantable film formulation. This result could be a solution to the premature drug release and dose dumping known to occur with the use of nanoparticles. In the light of the cell culture data, all nanoparticle formulations increased the anticancer effects of DOC in free
PDF
Album
Full Research Paper
Published 12 Jul 2017

Low uptake of silica nanoparticles in Caco-2 intestinal epithelial barriers

  • Dong Ye,
  • Mattia Bramini,
  • Delyan R. Hristov,
  • Sha Wan,
  • Anna Salvati,
  • Christoffer Åberg and
  • Kenneth A. Dawson

Beilstein J. Nanotechnol. 2017, 8, 1396–1406, doi:10.3762/bjnano.8.141

Graphical Abstract
  • whether the low amount of internalised nanoparticles observed by the different microscopy methods was due to low uptake or fast passage through the barrier. We found that the amount of SiO2-NPs in the basolateral chamber was less than 1 wt % of the applied apical dose, regardless of serum concentration or
  • ) may have exaggerated effects which will not be present for real barriers, where a lower dose is accumulated. On the other hand, lower internalised doses have also been found to activate different cellular pathways compared to those observed at higher nanoparticle loads [53]. Thus the use of cellular
PDF
Album
Supp Info
Full Research Paper
Published 07 Jul 2017

Carbon nanomaterials sensitize prostate cancer cells to docetaxel and mitomycin C via induction of apoptosis and inhibition of proliferation

  • Kati Erdmann,
  • Jessica Ringel,
  • Silke Hampel,
  • Manfred P. Wirth and
  • Susanne Fuessel

Beilstein J. Nanotechnol. 2017, 8, 1307–1317, doi:10.3762/bjnano.8.132

Graphical Abstract
  • contrast, the dose of platinum-based chemotherapeutics could only be reduced by up to 3-fold by combination with carbon nanomaterials. Furthermore, combinatory treatments with CNFs led mostly to an additive inhibition of short- and long-term proliferation compared to the individual treatments. Also, higher
  • survival as well as earlier treatment of micrometastases [3][4]. Potential disadvantages include delay of surgery, over-treatment of low-risk patients and systemic side effects from chemotherapy [3]. For instance, the systemic application of DTX leads to severe dose-limiting toxicities manifested as
  • usefulness and safety [5][6][7]. However, systemic chemotherapy is associated with severe side effects limiting the maximum drug dose and resulting in a diminished quality of life for the patients. Furthermore, the effective delivery and homogenous distribution of small molecules such as chemotherapeutics at
PDF
Album
Supp Info
Full Research Paper
Published 23 Jun 2017

Needs and challenges for assessing the environmental impacts of engineered nanomaterials (ENMs)

  • Michelle Romero-Franco,
  • Hilary A. Godwin,
  • Muhammad Bilal and
  • Yoram Cohen

Beilstein J. Nanotechnol. 2017, 8, 989–1014, doi:10.3762/bjnano.8.101

Graphical Abstract
  • human health related risks in a systematic manner based on toxicity, dose response curves and quantitative exposure assessment. These frameworks (i.e., EIA and RA) have also been incorporated into ecological risk assessment (ERA) [13], which is used to evaluate the likelihood of adverse environmental
  • , (ii) ENMs dose-response and dosimetry metrics, (ii) production volume and emission rates (including modes of release) of ENMs, (iii) environmental transformations, and (iv) distribution of ENMs in the environment and associated multimedia exposure levels [15][16]. Due to data gaps, RA of ENMs that
  • quantify the relevant ENM absorbed and/or effective doses and complicate the development of dose–response relationships. As defined by the United States Environmental Protection Agency (US EPA), “Risk characterization is an integral component of the risk assessment process for both ecological and health
PDF
Album
Supp Info
Review
Published 05 May 2017

Ion beam profiling from the interaction with a freestanding 2D layer

  • Ivan Shorubalko,
  • Kyoungjun Choi,
  • Michael Stiefel and
  • Hyung Gyu Park

Beilstein J. Nanotechnol. 2017, 8, 682–687, doi:10.3762/bjnano.8.73

Graphical Abstract
  • resultant pore diameter. In return, the pore dimension as a function of the exposure dose brings out the ion beam profiles. Using this method of determining an ion-beam point spread function, we verify a Gaussian profile of focused gallium ion beams. Graphene sputtering yield is extracted from the
  • source. Our method of profiling ion beams with 2D-layer perforation provides more information on ion beam profiles than the conventional sharp-edge scan method does. Keywords: exposure dose; focused ion beam; freestanding 2D layer; graphene; ion beam diameter; ion beam point spread function
  • strategy to measure FIB profiles is to exploit the milling effect of a bulk substrate by ion beams with a controlled beam dose. This method was actually used to estimate the focus spot size of one of the first Ga-FIBs [8]. In order to extract the ion beam profiles from such experiments more precisely, one
PDF
Album
Full Research Paper
Published 23 Mar 2017

Uptake of the proteins HTRA1 and HTRA2 by cells mediated by calcium phosphate nanoparticles

  • Olga Rotan,
  • Katharina N. Severin,
  • Simon Pöpsel,
  • Alexander Peetsch,
  • Melisa Merdanovic,
  • Michael Ehrmann and
  • Matthias Epple

Beilstein J. Nanotechnol. 2017, 8, 381–393, doi:10.3762/bjnano.8.40

Graphical Abstract
  • cell membrane with the help of calcium phosphate nanoparticles [8]. The presence of calcium phosphate in human hard tissue renders them inherently biocompatible [22] unless the nanoparticle dose is very high when it may cause an intracellular disturbance of the calcium level [23][24][25][26][27]. After
PDF
Album
Full Research Paper
Published 07 Feb 2017

Association of aescin with β- and γ-cyclodextrins studied by DFT calculations and spectroscopic methods

  • Ana I. Ramos,
  • Pedro D. Vaz,
  • Susana S. Braga and
  • Artur M. S. Silva

Beilstein J. Nanotechnol. 2017, 8, 348–357, doi:10.3762/bjnano.8.37

Graphical Abstract
  • ]. In vitro incubation with cells of the C6 (glioma) and A549 (lung adenocarcinoma) tumoural lines showed that aescin has potent dose- and time-dependent antiproliferative effects [8]. Studies with human castration-resistant prostate cancer, both in vitro, using the cell lines PC-3 and DU-145, and in
PDF
Album
Supp Info
Full Research Paper
Published 03 Feb 2017

Chitosan-based nanoparticles for improved anticancer efficacy and bioavailability of mifepristone

  • Huijuan Zhang,
  • Fuqiang Wu,
  • Yazhen Li,
  • Xiping Yang,
  • Jiamei Huang,
  • Tingting Lv,
  • Yingying Zhang,
  • Jianzhong Chen,
  • Haijun Chen,
  • Yu Gao,
  • Guannan Liu and
  • Lee Jia

Beilstein J. Nanotechnol. 2016, 7, 1861–1870, doi:10.3762/bjnano.7.178

Graphical Abstract
  • hepatocellular carcinoma) cells (Figure 7). CNs demonstrated no obvious toxicity to the four cancer cells under all the tested concentrations, indicating that Cs could be used as a safe drug carrier. However, MCNs could inhibit cell growth in a dose-dependant manner. In this experiment, we found that MIF had no
  • Care and Use Committee to reduce the suffering and use of animals. Oral administration Eight male SD rats were randomly divided into two groups (n = 4). Group 1 was given a single 30 mg/kg dose of MIF (in soybean oil solution) and Group 2 was given a single dose of MCNs equivalent to the same dosage of
  • for 48 h at 37 °C before subjecting them to MTT assay. *p < 0.05 and **p < 0.01 compared with the MIF group by the Student’s t-test. In vivo plasma concentration vs time of different MIF formulations. Male SD rats were given a single 30 mg/kg dose of MIF (in soybean oil solution) or a single dose of
PDF
Album
Full Research Paper
Published 28 Nov 2016

Active and fast charge-state switching of single NV centres in diamond by in-plane Al-Schottky junctions

  • Christoph Schreyvogel,
  • Vladimir Polyakov,
  • Sina Burk,
  • Helmut Fedder,
  • Andrej Denisenko,
  • Felipe Fávaro de Oliveira,
  • Ralf Wunderlich,
  • Jan Meijer,
  • Verena Zuerbig,
  • Jörg Wrachtrup and
  • Christoph E. Nebel

Beilstein J. Nanotechnol. 2016, 7, 1727–1735, doi:10.3762/bjnano.7.165

Graphical Abstract
  • according to a SRIM (stopping and range of ions in matter) simulation [24]. The implanted dose of nitrogen was 108 ions/cm2 covering homogenously the surface. The sample was annealed for 2 h at 800 °C in vacuum to create NV centres. The formation efficiency is about 1–10% [25][26] which leads to an NV
PDF
Album
Letter
Published 16 Nov 2016

Antitumor magnetic hyperthermia induced by RGD-functionalized Fe3O4 nanoparticles, in an experimental model of colorectal liver metastases

  • Oihane K. Arriortua,
  • Eneko Garaio,
  • Borja Herrero de la Parte,
  • Maite Insausti,
  • Luis Lezama,
  • Fernando Plazaola,
  • Jose Angel García,
  • Jesús M. Aizpurua,
  • Maialen Sagartzazu,
  • Mireia Irazola,
  • Nestor Etxebarria,
  • Ignacio García-Alonso,
  • Alberto Saiz-López and
  • José Javier Echevarria-Uraga

Beilstein J. Nanotechnol. 2016, 7, 1532–1542, doi:10.3762/bjnano.7.147

Graphical Abstract
  • microscope (Leika M651), a microcannula (0.014 in OD) was inserted through the splenic artery into the hepatic artery, and a Yasargil clip was placed to stabilize it. Using an infusion pump, 1 mL of saline or magnetic NP fluid (PBS with Fe3O4@PMAO_RGD, to be administered at a dose of 5 mg Fe/kg) was infused
PDF
Album
Supp Info
Full Research Paper
Published 28 Oct 2016
Other Beilstein-Institut Open Science Activities