Durable antimicrobial activity of fabrics functionalized with zeolite ion-exchanged nanomaterials against Staphylococcus aureus and Escherichia coli

• Perla Sánchez-López,
• Kendra Ramirez Acosta,
• Sergio Fuentes Moyado,
• Ruben Dario Cadena-Nava and
• Elena Smolentseva

Beilstein J. Nanotechnol. 2026, 17, 262–274, doi:10.3762/bjnano.17.18

• nanoparticles act against viruses involves the interaction with the surface of the NPs, leading to adhesion and inactivation, thereby preventing the virion from entering the host cell. NPs release ions or transfer them to microorganisms, inducing oxidative stress. Given these possible mechanisms, viral

• antimicrobial activity observed after five washing cycles further supports the strong adhesion and stability of the metal-loaded zeolites on the fabric surface. Based on those experiments, only minimal metal leaching during washing is expected. Conclusion This study successfully demonstrates the

• , consistent with their known antimicrobial properties. Notably, the treated fabrics retained substantial biocidal activity even after multiple washing cycles, indicating the strong adhesion and stability of the zeolite-based nanomaterials. These findings highlight the potential of zeolite-supported metal ions

Micro- and nanoscale effects in biological and bioinspired materials and surfaces

• Thies H. Büscher,
• Rhainer Guillermo Ferreira,
• Manuela Rebora and
• Stanislav N. Gorb

Beilstein J. Nanotechnol. 2026, 17, 214–217, doi:10.3762/bjnano.17.14

• Chimica, Biologia e Biotecnologie, University of Perugia, Via Elce di Sotto 8, 06121 Perugia, Italy 10.3762/bjnano.17.14 Keywords: adhesion; bioengineering; functional morphology; material properties; medical coatings; microstructures; nanostructures; optics; structure–function relationships; Micro- and

• nanostructures play a crucial role in shaping the physical and functional properties of living organisms. They are the basis of key biological phenomena, such as coloration, adhesion, and mechanical stability, and influence the way how organisms interact with light, fluids, and forces at different scales. The

• bioinspired surfaces and their tribological characteristics (friction, wear resistance, and adhesion), as well as self-cleaning and optical properties, underscoring the overarching aim of the symposium to integrate biological phenomena and materials science towards biomimetic approaches. The fruitful

Influence of surface characteristics on the in vitro stability and cell uptake of nanoliposomes for brain delivery

• Dushko Shalabalija,
• Ljubica Mihailova,
• Nikola Geskovski,
• Andreas Zimmer,
• Otmar Geiss,
• Sabrina Gioria,
• Diletta Scaccabarozzi and
• Marija Glavas Dodov

Beilstein J. Nanotechnol. 2026, 17, 139–158, doi:10.3762/bjnano.17.9

• uncompetitive movement of the nanosystems, either directly through membrane phospholipids (simple diffusion) or in combination with membrane proteins (facilitated diffusion) [8][34]. Therefore, endocytosis is a process that occurs through membrane–particle adhesion followed by elastic deformation of the cell

• cell recognition, cell membrane adhesion and interactions, the internalization mechanisms, as well as the intracellular trafficking of nanosystems since it gives them new biological identity [39]. The impact of PC on particle–cell interactions varies based on particle properties and cellular components

• formation. Hence, these results only confirm the statement regarding the opposite dependence between the particle size and hCMEC/D3 liposomal uptake and adhesion as well as the alterations on the internalization promoted by the adsorbed serum proteins onto the surface of NLs [46]. On the other hand, NLb2

Development and in vitro evaluation of liposomes and immunoliposomes containing 5-fluorouracil and R-phycoerythrin as a potential phototheranostic system for colorectal cancer

• Raissa Rodrigues Camelo,
• Vivianne Cortez Sombra Vandesmet,
• Octavio Vital Baccallini,
• José de Brito Vieira Neto,
• Thais da Silva Moreira,
• Luzia Kalyne Almeida Moreira Leal,
• Claudia Pessoa,
• Daniel Giuliano Cerri,
• Maria Vitória Lopes Badra Bentley,
• Josimar O. Eloy,
• Ivanildo José da Silva Júnior and
• Raquel Petrilli

Beilstein J. Nanotechnol. 2026, 17, 97–121, doi:10.3762/bjnano.17.7

• ™ 488. 2.7 Cellular uptake Cellular internalization was assessed by confocal microscopy. For confocal microscopy, 1 × 106 cells were seeded onto 6-well plates containing sterile cover slides and 1 mL of culture medium per well. After allowing cell adhesion overnight, the culture medium was removed and 1

• dehydration process and adhesion forces onto the substrate [57][58]. On the other hand, the z-axis and 3D projections for HSPC-IM-R-PE (Figure 3E and Figure 3H, respectively) demonstrated a more irregular nanoparticle surface, with visibly rougher and more heterogeneous topography, a result consistent with

Functional surface engineering for cultural heritage protection: the role of superhydrophobic and superoleophobic coatings – a comprehensive review

• Giuseppe Cesare Lama,
• Marino Lavorgna,
• Letizia Verdolotti,
• Federica Recupido,
• Giovanna Giuliana Buonocore and
• Bharat Bhushan

Beilstein J. Nanotechnol. 2026, 17, 63–96, doi:10.3762/bjnano.17.6

• acrylic resin (B44) or INCRALAC) and waxes (like Carnauba wax) are still widely used, often in combination with each other, being easily commercially available and well-established solutions for quick metal, glass, or stone artwork protection (especially for frescoes). They have good initial adhesion and

• stages of application [51]. For these reasons trend is to use other engineered materials. The tailoring of coating materials must be guided by the nature of the substrate since porosity, roughness, and coating thickness directly affect adhesion, durability, hydrophobicity, and ultimately compliance with

• Penteli) using a simple layer-by-layer spray surface functionalization technique. The authors claimed that the components were water-soluble, easily accessible, and with the possibility to tune properties like adhesion, self-healing, and weathering resistance by optimizing the procedure for their

Subdigital integumentary microstructure in Cyrtodactylus (Squamata: Gekkota): do those lineages with incipiently expressed toepads exclusively exhibit adhesive setae?

• Philipp Ginal,
• Yannick Ecker,
• Timothy Higham,
• L. Lee Grismer,
• Benjamin Wipfler,
• Dennis Rödder,
• Anthony Russell and
• Jendrian Riedel

Beilstein J. Nanotechnol. 2026, 17, 38–56, doi:10.3762/bjnano.17.4

• surfaces, either by employing dry adhesion via microstructures, or wet adhesion, which is additionally supported by secretions [1][2][3][4][5]. In lizards, subdigital adhesive microstructures facilitating dry adhesion evolved independently in anoles, some skinks, and multiple times in geckos [3][6][7][8

• , in association with a long stalk, the resulting low effective bending stiffness could hinder the proper function of the spatulate tips, which depend on van der Waals forces to achieve effective adhesion [74][75][76][77][78][79]. Given that density is calculated as the number of stalks per unit area

• setae are known to enhance adhesion on inclined smooth surfaces [80][81][82], which are more prevalent in arboreal than in saxicoline habitats [31][83]. Conversely, species occupying terrestrial or generalist habitats were expected to lack traits associated with the enhancement of adhesive capabilities

Quantitative estimation of nanoparticle/substrate adhesion by atomic force microscopy

• Aydan Çiçek,
• Markus Kratzer,
• Christian Teichert and
• Christian Mitterer

Beilstein J. Nanotechnol. 2026, 17, 1–14, doi:10.3762/bjnano.17.1

• , Leoben, Austria 10.3762/bjnano.17.1 Abstract Understanding nanoparticle adhesion to substrates is the key for their stability and performance in many applications, including energy systems, nanofabrication, catalysis, and electronic devices. In this study, we present a methodology for examining adhesion

• calibration achieved through wedge and diamagnetic lateral force calibrator methods. The work of adhesion was quantified by integrating the obtained lateral forces over the distance moved during manipulation, revealing a non-monotonic dependency on nanoparticle size with maximum adhesion observed for

• particles between 6 and 12 nm. In addition, an applied positive substrate bias voltage led to more energetic landing conditions and thus to increased adhesion forces. This study underscores the suitability of atomic force microscopy in characterizing adhesion on the nanoscale and offers insights into future

Multifrequency AFM integrating PeakForce tapping and higher eigenmodes for heterogeneous surface characterization

• Yanping Wei,
• Jiafeng Shen,
• Yirong Yao,
• Xuke Li,
• Ming Li and
• Peiling Ke

Beilstein J. Nanotechnol. 2025, 16, 2077–2085, doi:10.3762/bjnano.16.142

• environments such as liquids [18][19]. As demonstrated by force–distance curve analyses [19], PFT enables direct extraction of quantitative mechanical properties (e.g., Young’s modulus and adhesion) for material discrimination. However, this capability is constrained by the requirement for precise probe

• stiffness, insufficient sample deformation led to significant variability in modulus measurements (Figure 3b), indicating the ScanAsyst-Air probe was unsuitable for reliable Young’s modulus quantification. Comparative analysis revealed a high degree of similarity in the topography, modulus, and adhesion

• phase images compared to adhesion maps. Notably, the third eigenmode phase image provided the highest contrast, enabling clear distinction between thinner and thicker nanosheet regions. For the NSC15/Al BS probe (Figure 4), the lock-in amplifier detected the first two eigenmodes. Measurements were

Molecular and mechanical insights into gecko seta adhesion: multiscale simulations combining molecular dynamics and the finite element method

• Yash Jain,
• Saeed Norouzi,
• Tobias Materzok,
• Stanislav N. Gorb and
• Florian Müller-Plathe

Beilstein J. Nanotechnol. 2025, 16, 2055–2076, doi:10.3762/bjnano.16.141

• University, Am Botanischen Garten 1–9, D-24118 Kiel, Germany 10.3762/bjnano.16.141 Abstract Gecko adhesion, enabled by micro- and nanoscale structures known as setae and spatulae, has prompted extensive research. We present a concurrent multiscale computational model of a seta that integrates molecular

• . The model reproduces key aspects of spatula behavior during adhesion and detachment, showing that spatula–substrate contact evolves through a combination of bending, sliding, and peeling, depending on the spatula’s initial orientation. Our results further demonstrate that lateral sliding can delay

• detachment, thereby enhancing adhesion strength. The computed pull-off forces and observed mechanisms are consistent with atomic force microscopy measurements and previous simulations. These results align with existing experimental and computational studies. They also overcome scale and resolution

Beyond the shell: exploring polymer–lipid interfaces in core–shell nanofibers to carry hyaluronic acid and β-caryophyllene

• Aline Tavares da Silva Barreto,
• Francisco Alexandrino-Júnior,
• Bráulio Soares Arcanjo,
• Paulo Henrique de Souza Picciani and
• Kattya Gyselle de Holanda e Silva

Beilstein J. Nanotechnol. 2025, 16, 2015–2033, doi:10.3762/bjnano.16.139

• an interconnected nanoarchitecture, forming a membrane with porosity that enhances surface hydrophobicity and promotes strong adhesion forces with water [61]. In core–shell nanofibers, the use of PLA as the shell inherently implies that the nanofibers will exhibit a hydrophobic surface due to the

• hydrophobicity, indicating strong anti-bioadhesive properties. This feature is particularly advantageous for preventing membrane adhesion to tissues, such as in tendon and abdominal surgeries [78], and can also reduce bacterial adhesion [79], enhance resistance to moisture, and protect the hydrophilic core from

• of the core, suggests a viable mechanism for the controlled release of active ingredients through diffusion. The high surface hydrophobicity of the nanofibers, confirmed by contact angle measurements, reinforces their potential use in applications that require low tissue adhesion, such as non

The cement of the tube-dwelling polychaete Sabellaria alveolata: a complex composite adhesive material

• Emilie Duthoo,
• Aurélie Lambert,
• Pierre Becker,
• Carla Pugliese,
• Jean-Marc Baele,
• Arnaud Delfairière,
• Matthew J. Harrington and
• Patrick Flammang

Beilstein J. Nanotechnol. 2025, 16, 1998–2014, doi:10.3762/bjnano.16.138

• underwater adhesive materials for various applications, particularly in the industrial and biomedical fields [3][4]. Polychaetes of the family Sabellariidae are one of the model organisms that have been studied extensively for their adhesion and have fascinated researchers since the 18th century [5]. Two

• occurrence of protein phosphorylation in biological adhesion has been reported in various organisms such as sandcastle worms, sea cucumbers, and mussels, and proposed to be an important component for their adhesion [19][44]. For example, mfp-5, an adhesive protein found in the mussel foot, has been shown to

• acids in adhesion, the enzymes involved in phosphorylation are not fully understood. In a previous study, researchers attempted to identify and locate a serine kinase responsible for phosphorylating the serine residues of the Pc-3 adhesive proteins in P. californica, but the sequence could not be found

Laser ablation in liquids for shape-tailored synthesis of nanomaterials: status and challenges

• Natalie Tarasenka

Beilstein J. Nanotechnol. 2025, 16, 1963–1997, doi:10.3762/bjnano.16.137

• nanostructures for both wavelengths used. Therefore, the authors attribute the formation of sheet-shaped particles to the adhesion of the spherical NPs. The increase of the laser pulse energy favoured the formation of spherical particles and hindered the growth of sheet-shaped structures, which the authors

• explained by the decrease of the adhesion of NPs. The variation of the NP shape can be more significant in organic liquids. For example, Singh et al. [33] produced drop-shaped ZnO quantum dots by laser ablation of Zn in methanol, which were prone to spontaneous self-assembly after the end of the synthesis

Mechanical property measurements enabled by short-term Fourier-transform of atomic force microscopy thermal deflection analysis

• Thomas Mathias,
• Roland Bennewitz and
• Philip Egberts

Beilstein J. Nanotechnol. 2025, 16, 1952–1962, doi:10.3762/bjnano.16.136

• of adhesion, which can be calculated from the pull-off force in experiments. We calculated the Tabor parameter, μT, and the transition parameter, λ, for each material pair, which are given in Table 2. Rather than fitting data with Tabor parameters smaller than 0.1 with the DMT model and greater than

Evaluating metal-organic precursors for focused ion beam-induced deposition through solid-layer decomposition analysis

• Benedykt R. Jany,
• Katarzyna Madajska,
• Aleksandra Butrymowicz-Kubiak,
• Franciszek Krok and
• Iwona B. Szymańska

Beilstein J. Nanotechnol. 2025, 16, 1942–1951, doi:10.3762/bjnano.16.135

• significant beam-induced substrate defects (e.g., Ga atom implantation). Additionally, material growth is required to compete with the FIB milling process [4][9]. The use of ions instead of electrons, like in FEBID, offers several benefits, including enhanced film quality and adhesion, better control over the

Self-assembly and adhesive properties of Pollicipes pollicipes barnacle cement protein cp19k: influence of pH and ionic strength

• Shrutika Sawant,
• Anne Marie Power and
• J. Gerard Wall

Beilstein J. Nanotechnol. 2025, 16, 1863–1872, doi:10.3762/bjnano.16.129

• under low pH/low salt concentration conditions, while pre-formed fibrils retained their adhesion ability upon switching to a high pH/high salt concentration environment, which was designed to mimic the change in the protein environment upon secretion in vivo. These findings support the hypothesis that

• fibril formation occurs in the acidic, iso-osmotic gland of the barnacle, with delayed cement curing enabling fibril secretion for sustained adhesion of the organism. The study provides insight into the environmental sensitivity of cp19k structure–function dynamics and may support the design of

• , ship hulls, and even other organisms [1]. These bioadhesives function under challenging aquatic conditions, including high and fluctuating salinity, and constant turbulence. Unlocking the molecular mechanisms behind their ability to achieve robust, long-term adhesion under wet and dynamic conditions

Exploring the potential of polymers: advancements in oral nanocarrier technology

• Rousilândia de Araujo Silva,
• Igor Eduardo Silva Arruda,
• Luise Lopes Chaves,
• Mônica Felts de La Roca Soares and
• Jose Lamartine Soares Sobrinho

Beilstein J. Nanotechnol. 2025, 16, 1751–1793, doi:10.3762/bjnano.16.122

• macromolecules composed of repeating monomers linked by covalent bonds [90]. These materials are highly attractive as vehicles for oral drug delivery systems due to their strong mucosal adhesion properties and their ability to enhance paracellular transport of drug molecules. Additionally, they are easy to

Advances of aptamers in esophageal cancer diagnosis, treatment and drug delivery

• Yang Fei,
• Hui Xu,
• Chunwei Zhang,
• Jingjing Wang and
• Yong Jin

Beilstein J. Nanotechnol. 2025, 16, 1734–1750, doi:10.3762/bjnano.16.121

• domains, including RGD [94], and participates in cell adhesion, migration, proliferation, and signal transduction [95]. Five subtypes of OPN are co-upregulated in primary EAC, among which OPNc expression was relatively low, inducing cell separation via an integrin-independent binding mode, probably due to

Multifunctional anionic nanoemulsion with linseed oil and lecithin: a preliminary approach for dry eye disease

• Niédja Fittipaldi Vasconcelos,
• Almerinda Agrelli,
• Rayane Cristine Santos da Silva,
• Carina Lucena Mendes-Marques,
• Isabel Renata de Souza Arruda,
• Priscilla Stela Santana de Oliveira,
• Mércia Liane de Oliveira and
• Giovanna Machado

Beilstein J. Nanotechnol. 2025, 16, 1711–1733, doi:10.3762/bjnano.16.120

• metalloproteinase-9, intercellular adhesion molecule 1, and tumor necrosis factor [34][35][36]. Downie et al. reported strong clinical evidence supporting the efficacy of nanolipid carrier eye drops infused with omega–3 fatty acids in stabilizing the tear film in patients with meibomian gland dysfunction [31]. In

Nanotechnology-based approaches for the removal of microplastics from wastewater: a comprehensive review

• Nayanathara O Sanjeev,
• Manjunath Singanodi Vallabha and
• Rebekah Rubidha Lisha Rabi

Beilstein J. Nanotechnol. 2025, 16, 1607–1632, doi:10.3762/bjnano.16.114

• contact angle decreasing from 84.6° ± 1° to 64.2° ± 1.2°), work of adhesion, wetting energy, porosity, and pore dimensions. Among various loadings, the membrane with 0.5 wt % MIL-100 (Fe) (M0.5) showed the best overall performance. It delivered a pure water flux over ten times higher than M0 and achieved

Bioinspired polypropylene-based functionally graded materials and metamaterials modeling the mistletoe–host interface

• Lina M. Rojas González,
• Naeim Ghavidelnia,
• Christoph Eberl and
• Max D. Mylo

Beilstein J. Nanotechnol. 2025, 16, 1592–1606, doi:10.3762/bjnano.16.113

• demonstrated the potential for creating functionally graded structures using multimaterial 3D printing [18][19][20]. However, these methods mainly focus on structural gradients [21] and face significant challenges in part integrity due to the layer-by-layer fabrication process, which results in poor adhesion

Laser processing in liquids: insights into nanocolloid generation and thin film integration for energy, photonic, and sensing applications

• Akshana Parameswaran Sreekala,
• Pooja Raveendran Nair,
• Jithin Kundalam Kadavath,
• Bindu Krishnan,
• David Avellaneda Avellaneda,
• M. R. Anantharaman and
• Sadasivan Shaji

Beilstein J. Nanotechnol. 2025, 16, 1428–1498, doi:10.3762/bjnano.16.104

• deposited by doctor blade exhibit higher porosity and distinct clustering compared to those made by laser ablation. This increased porosity in the doctor blade films is likely responsible for the better dye absorption observed. However, a disadvantage of the doctor blade method is the poor adhesion of the

• substrates kept on a temperature-controlled hotplate. The resulting films were stable and uniform with good adhesion to the substrates. The average thickness of films by spraying one liter of nanocolloid was around 1 mm as evaluated by SEM and profilometry. The morphology of as-deposited and annealed SnS

Synthesis and antibacterial properties of nanosilver-modified cellulose triacetate membranes for seawater desalination

• Lei Wang,
• Shizhe Li,
• Kexin Xu,
• Wenjun Li,
• Ying Li and
• Gang Liu

Beilstein J. Nanotechnol. 2025, 16, 1380–1391, doi:10.3762/bjnano.16.100

• the Ag@PCTA membrane illustrate a well-defined PDA layer that maintains its uniformity and adhesion to the underlying CTA substrate (Figure 4f). Notably, Ag nanoparticles are not discernible in the cross-sectional view, indicating their confinement within the PDA layer. The underlying CTA layer

Enhancing the therapeutical potential of metalloantibiotics using nano-based delivery systems

• Alejandro Llamedo,
• Marina Cano,
• Raquel G. Soengas and
• Francisco J. García-Alonso

Beilstein J. Nanotechnol. 2025, 16, 1350–1366, doi:10.3762/bjnano.16.98

• activity was attributed to the synergistic effect of the bismuth complex and tobramycin, as well as the ability of liposomes to facilitate intracellular delivery. Furthermore, LipoBiEDT-TOB effectively inhibited bacterial adhesion of B. cenocepacia to lung cells, supporting its potential to interfere with

Hydrogels and nanogels: effectiveness in dermal applications

• Jéssica da Cruz Ludwig,
• Diana Fortkamp Grigoletto,
• Daniele Fernanda Renzi,
• Wolf-Rainer Abraham,
• Daniel de Paula and
• Najeh Maissar Khalil

Beilstein J. Nanotechnol. 2025, 16, 1216–1233, doi:10.3762/bjnano.16.90

• . (2017), the authors developed an innovative hydrogel that can be directly injected into the injured skin. The benefits associated with wound healing stand out: self-regeneration potential, antibacterial activity, neutralization of free radicals, high adhesion to the skin, and biocompatibility. These

Mechanical stability of individual bacterial cells under different osmotic pressure conditions: a nanoindentation study of Pseudomonas aeruginosa

• Lizeth García-Torres,
• Idania De Alba Montero,
• Eleazar Samuel Kolosovas-Machuca,
• Facundo Ruiz,
• Sumati Bhatia,
• Jose Luis Cuellar Camacho and
• Jaime Ruiz-García

Beilstein J. Nanotechnol. 2025, 16, 1171–1183, doi:10.3762/bjnano.16.86

• . Therefore, the pre-programed grid in FV defines the amount of information (number of nanoindentations per scanned line) taken from the sample surface and also its resolution. Typical parameters obtained using the FV mode are the height, stiffness, adhesion, elasticity modulus, and dissipation of the sample

• conditions. Of particular interest was the extraction and comparison of nanomechanical maps obtained in the low range of loading forces to quantify its morphology, membrane stiffness, Young’s modulus of elasticity and adhesion when PA was tested in hypotonic (Milli-Q water), isotonic (0.1 M phosphate

• bacterial adhesion through short-range electrostatic and hydrophobic interactions. Before deposition on the PLL-coated substrate, the bacterial suspension was centrifuged at 2500 rpm for 3 min, and the resulting supernatant was removed. The bacteria were then resuspended in 150 μL of PBS to increase their