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Search for "transition metal catalysis" in Full Text gives 90 result(s) in Beilstein Journal of Organic Chemistry.

Post-Ugi gold-catalyzed diastereoselective domino cyclization for the synthesis of diversely substituted spiroindolines

  • Amit Kumar,
  • Dipak D. Vachhani,
  • Sachin G. Modha,
  • Sunil K. Sharma,
  • Virinder S. Parmar and
  • Erik V. Van der Eycken

Beilstein J. Org. Chem. 2013, 9, 2097–2102, doi:10.3762/bjoc.9.246

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  • materials. Based on this work and our continuous interest in transition metal catalysis [45][46][47][48][49][50][51][52][53][54], multicomponent reactions [55][56][57] and the chemistry of the indole core [58][59][60], we herein report a post-Ugi gold-catalyzed intramolecular domino cyclization sequence for
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Published 14 Oct 2013

Homolytic substitution at phosphorus for C–P bond formation in organic synthesis

  • Hideki Yorimitsu

Beilstein J. Org. Chem. 2013, 9, 1269–1277, doi:10.3762/bjoc.9.143

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  • reactions such as nucleophilic substitution of P–X compounds with organometallic reagents, nucleophilic substitution of alkyl halides with phosphorus nucleophiles, and nucleophilic addition to polar unsaturated bonds. Recent advances in transition-metal catalysis have realized catalytic cross-coupling
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Review
Published 28 Jun 2013

Efficient Cu-catalyzed base-free C–S coupling under conventional and microwave heating. A simple access to S-heterocycles and sulfides

  • Silvia M. Soria-Castro and
  • Alicia B. Peñéñory

Beilstein J. Org. Chem. 2013, 9, 467–475, doi:10.3762/bjoc.9.50

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  • compounds. The formation of C–S bonds can also be accomplished in good to excellent yields by transition-metal catalysis [10][11], mainly using palladium [12], copper [13][14][15][16], nickel [17][18] and iron [19][20] salts. Aryl coupling reactions employing different palladium species as catalysts
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Published 04 Mar 2013

Recent advances in direct C–H arylation: Methodology, selectivity and mechanism in oxazole series

  • Cécile Verrier,
  • Pierrik Lassalas,
  • Laure Théveau,
  • Guy Quéguiner,
  • François Trécourt,
  • Francis Marsais and
  • Christophe Hoarau

Beilstein J. Org. Chem. 2011, 7, 1584–1601, doi:10.3762/bjoc.7.187

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  • in this article. Methodologies, selectivity, mechanism and future aspects are presented. Keywords: ate complex; catalytic direct arylation; mechanism; oxazole; selectivity; transition-metal catalysis; Introduction Deprotonative metalation of aromatics is widely used as a powerful method for
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Review
Published 29 Nov 2011

One-pot four-component synthesis of pyrimidyl and pyrazolyl substituted azulenes by glyoxylation–decarbonylative alkynylation–cyclocondensation sequences

  • Charlotte F. Gers,
  • Julia Rosellen,
  • Eugen Merkul and
  • Thomas J. J. Müller

Beilstein J. Org. Chem. 2011, 7, 1173–1181, doi:10.3762/bjoc.7.136

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  • traditional multistep syntheses. Thus, they can be considered to be economically and ecologically efficient [9][10]. In particular, multicomponent syntheses of heterocycles initiated by transition metal catalysis received increasing attention in the past decade [11]. As a one-pot synthetic methodology, this
  • novel concept combines the unique reactivity patterns of transition metal catalysis with fundamental organic reactivity, in a sequential or consecutive fashion. Over the years, we have contributed to this concept through Pd/Cu-catalyzed accesses to enones and ynones and the in situ transformation of
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Published 26 Aug 2011

Multicomponent reactions

  • Thomas J. J. Müller

Beilstein J. Org. Chem. 2011, 7, 960–961, doi:10.3762/bjoc.7.107

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  • lead structures of active agents, catalysts and even novel molecule-based materials. This Thematic Series on multicomponent reactions represents a snapshot of a highly dynamic field and spans a broad range, from recent advances in isonitrile-based MCR to transition metal catalysis in MCR; from peptidic
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Editorial
Published 13 Jul 2011

Highly efficient gold(I)-catalyzed Overman rearrangement in water

  • Dong Xing and
  • Dan Yang

Beilstein J. Org. Chem. 2011, 7, 781–785, doi:10.3762/bjoc.7.88

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  • allylic trichloroacetimidates to allylic trichloroacetamides (Overman rearrangement) is a powerful and attractive strategy for the synthesis of allylic amines from readily available allylic alcohols [1][2]. This transformation can be conducted thermally at high temperatures or by transition metal
  • catalysis under very mild conditions [3][4][5][6][7]. Asymmetric induction has been achieved with certain types of transition metal catalysts (e.g., palladium complexes) in combination with chiral ancillary ligands [8][9][10][11][12][13]. However, although a large number of late transition metal catalysts
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Letter
Published 08 Jun 2011

Continuous flow hydrogenation using polysilane-supported palladium/alumina hybrid catalysts

  • Hidekazu Oyamada,
  • Takeshi Naito and
  • Shū Kobayashi

Beilstein J. Org. Chem. 2011, 7, 735–739, doi:10.3762/bjoc.7.83

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  • and substantially increase production. We also recently reported novel transition metal catalysis involving the immobilization of Pd or Pt onto polysilane supports by the microencapsulation method [12]. The Pd catalyst (Pd/PSi) had high activity with no or very little leaching of Pd, and it could be
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Letter
Published 31 May 2011
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  • , arylsulfonyl chlorides and arenediazonium salts with arylboronic acids that gave biaryls in good to excellent yields [28][31][32]. As part of our ongoing investigations aimed at the development of transition metal catalysis, we report here that the Suzuki–Miyaura cross-couplings of 1-aryltriazenes with
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Published 28 Jun 2010

A thermally-induced, tandem [3,3]-sigmatropic rearrangement/[2 + 2] cycloaddition approach to carbocyclic spirooxindoles

  • Kay M. Brummond and
  • Joshua M. Osbourn

Beilstein J. Org. Chem. 2010, 6, No. 33, doi:10.3762/bjoc.6.33

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  • rearrangement of the propargyl acetate 9a using transition metal catalysis (AuCl3 10 mol %, toluene, 1 h, rt) led to hydrolysis of the allenyl acetate functionality. This densely functionalized alkylidene cyclobutene 10a is postulated to arise via the [2 + 2] cycloaddition reaction between the alkyne and the
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Preliminary Communication
Published 08 Apr 2010

A review of new developments in the Friedel–Crafts alkylation – From green chemistry to asymmetric catalysis

  • Magnus Rueping and
  • Boris J. Nachtsheim

Beilstein J. Org. Chem. 2010, 6, No. 6, doi:10.3762/bjoc.6.6

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  • simultaneously, an acid-catalyzed ortho-arylation of aniline employing the strong Brønsted acid PhNH3B(C6F5)4•Et2O was developed by Bergman et al. indicating the close relationship between strong Brønsted acid- and transition-metal catalysis [70]. A double ortho-hydroarylation of anilines with styrenes was
  • optical active ligands for enantioselective transition-metal catalysis (Scheme 22) [71]. To the best of our knowledge, efficient ortho-benzylations of anilines with benzyl alcohols as alkylating reagents have yet to be described [15]. Catalytic Friedel–Crafts allylations Allylated arenes represent
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Review
Published 20 Jan 2010

Can we measure catalyst efficiency in asymmetric chemical reactions? A theoretical approach

  • Shaimaa El-Fayyoumy,
  • Matthew H. Todd and
  • Christopher J. Richards

Beilstein J. Org. Chem. 2009, 5, No. 67, doi:10.3762/bjoc.5.67

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  • chemistry [1]. Enormous progress has been made in recent years, most notably in homogenous transition metal catalysis, organocatalysis and enzyme-catalysed reactions. It is therefore surprising that there is no generally accepted measure for the effectiveness of a catalytic reaction. That is to say when we
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Commentary
Published 19 Nov 2009

Expedient syntheses of the N-heterocyclic carbene precursor imidazolium salts IPr·HCl, IMes·HCl and IXy·HCl

  • Lukas Hintermann

Beilstein J. Org. Chem. 2007, 3, No. 22, doi:10.1186/1860-5397-3-22

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  • involving a 1,5-dipolar electrocyclization is proposed. Background Imidazolylidene carbenes have been investigated as ligands in coordination chemistry, as powerful steering/controlling elements in transition-metal catalysis,[1][2] and more recently as metal-free catalysts for organic reactions[3][4]. Some
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Published 28 Aug 2007

An exceptional P-H phosphonite: Biphenyl- 2,2'-bisfenchylchlorophosphite and derived ligands (BIFOPs) in enantioselective copper- catalyzed 1,4-additions

  • T. Kop-Weiershausen,
  • J. Lex,
  • J.-M. Neudörfl and
  • B. Goldfuss

Beilstein J. Org. Chem. 2005, 1, No. 6, doi:10.1186/1860-5397-1-6

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  • the phosphorus atoms in biphenyl-2,2'-bisfenchylphosphites (BIFOPs) founds the special suitability for BIFOP-H (3) as P-H phosphonite ligand in transition metal catalysis. This points to promising applications of 3 or analogue P-H ligands in enantioselective catalysis. X-ray crystal structure of BIFOP
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Published 26 Aug 2005

Mixtures of monodentate P-ligands as a means to control the diastereoselectivity in Rh-catalyzed hydrogenation of chiral alkenes

  • Manfred T. Reetz and
  • Hongchao Guo

Beilstein J. Org. Chem. 2005, 1, No. 3, doi:10.1186/1860-5397-1-3

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  • new approach in the area of combinatorial asymmetric transition metal catalysis:[19][20] The use of mixtures of two chiral monodentate ligands La and Lb in metal catalysts of the type ML2, leading to two so-called homo-combinations and one hetero-combination which are in equilibrium with one another
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Preliminary Communication
Published 26 Aug 2005
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