Graphene oxide–chloroquine conjugate induces DNA damage in A549 lung cancer cells through autophagy modulation

• Braham Dutt Arya,
• Sandeep Mittal,
• Prachi Joshi,
• Alok Kumar Pandey,
• Jaime E. Ramirez-Vick,
• Govind Gupta and
• Surinder P. Singh

Beilstein J. Nanotechnol. 2025, 16, 316–332, doi:10.3762/bjnano.16.24

• . P4170), Triton X-100 (Cat. No. T8787), monodansylcadaverine (MDC; Cat. No. D4008), anti-SQSTM1 (Cat. No. P0067), anti-MLKL primary antibody (Cat. No. SAB5700808), protein A/G agarose beads (Cat. No. IP10), and hydrogen peroxide (H2O2; Cat. No. H1009) were purchased from Sigma-Aldrich (St. Louis, MO, USA

Unveiling the potential of alginate-based nanomaterials in sensing technology and smart delivery applications

• Shakhzodjon Uzokboev,
• Khojimukhammad Akhmadbekov,
• Ra’no Nuritdinova,
• Salah M. Tawfik and
• Yong-Ill Lee

Beilstein J. Nanotechnol. 2024, 15, 1077–1104, doi:10.3762/bjnano.15.88

• discussed, including drug delivery and environmental sensing applications for humidity, heavy metals, and hydrogen peroxide. Moreover, biomedical sensing applications of alginate-based nanoparticles regarding various analytes such as glucose, cancer cells, pharmaceutical drugs, and human motion will also be

• glyoxal from water. An exceptional formaldehyde adsorption capacity of 58.30 mg/g and an adsorption removal effectiveness of 93.5% was demonstrated for APOF@ZIF-8/CS [15]. Hydrogen peroxide sensing: Hydrogen peroxide (H2O2) sensing is a crucial aspect of various fields, including biomedical research and

• environmental monitoring. Accurate detection and measurement of H2O2 levels is vital for understanding its role in biological processes, diagnosing diseases, and monitoring environmental pollutants [114]. Alginate-based nanoparticles have depicted great potential in hydrogen peroxide sensing. A silver/poly(3

A review on the structural characterization of nanomaterials for nano-QSAR models

• Salvador Moncho,
• Eva Serrano-Candelas,
• Jesús Vicente de Julián-Ortiz and
• Rafael Gozalbes

Beilstein J. Nanotechnol. 2024, 15, 854–866, doi:10.3762/bjnano.15.71

• its interaction with other substances, as for example using the maximum salt concentration in the medium with no significant coagulation or the rate constant of its oxidation by hydrogen peroxide [68]. It should be noted that the use of experimental descriptors can be exclusive, and there are models

Intermixing of MoS₂ and WS₂ photocatalysts toward methylene blue photodegradation

• Maryam Al Qaydi,
• Nitul S. Rajput,
• Michael Lejeune,
• Abdellatif Bouchalkha,
• Mimoun El Marssi,
• Steevy Cordette,
• Chaouki Kasmi and
• Mustapha Jouiad

Beilstein J. Nanotechnol. 2024, 15, 817–829, doi:10.3762/bjnano.15.68

• electrons (e−), leading to the formation of superoxide anions (O2−) [43]. The adsorbed oxygen has the ability to undergo a reaction with two electrons, resulting in the formation of hydrogen peroxide (H2O2). Hydrogen peroxide subsequently reacts with an electron, forming hydroxyl radicals (•OH), which are

Simultaneous electrochemical determination of uric acid and hypoxanthine at a TiO₂/graphene quantum dot-modified electrode

• Vu Ngoc Hoang,
• Dang Thi Ngoc Hoa,
• Nguyen Quang Man,
• Le Vu Truong Son,
• Le Van Thanh Son,
• Vo Thang Nguyen,
• Le Thi Hong Phong,
• Ly Hoang Diem,
• Kieu Chan Ly,
• Ho Sy Thang and
• Dinh Quang Khieu

Beilstein J. Nanotechnol. 2024, 15, 719–732, doi:10.3762/bjnano.15.60

• HYP using a TiO2/GQDs-modified electrode were addressed. Experimental Materials Coffee grounds were collected from the local area. Anatase (98%), hydrogen chloride (39%), hydrogen peroxide (30%), boric acid (99%), phosphoric acid (85%), acetic acid (99%), uric acid (99%), and hypoxanthine (99%) were

Laser synthesis of nanoparticles in organic solvents – products, reactions, and perspectives

• Theo Fromme,
• Sven Reichenberger,
• Katharine M. Tibbetts and
• Stephan Barcikowski

Beilstein J. Nanotechnol. 2024, 15, 638–663, doi:10.3762/bjnano.15.54

• nanoparticle synthesis in water is always accompanied by the production of gases [66][67]. Although gas formation has often been attributed to the vaporization of water, the formation of hydrogen and oxygen also occurs. Additionally, the formation of hydrogen peroxide was observed during LAL [50][51] and LRL

• oxygen species (ROS), for example, hydrogen peroxide, hydroxyl radicals, or dissolved oxygen, react with the particles leading to their surface oxidation. During irradiation of water with intense laser pulses, a weakly ionized plasma forms because of optical breakdown, supercontinuum emission, or both

• added different additives. In the case of gaseous additives (nitrogen, carbon dioxide, and argon), they saturated the solution by bubbling. Further additives were 0.3 vol % hydrogen peroxide and 0.2 vol % water (for ethanol only). Depending on the chosen additive, they found a different degree of

Classification and application of metal-based nanoantioxidants in medicine and healthcare

• Nguyen Nhat Nam,
• Nguyen Khoi Song Tran,
• Tan Tai Nguyen,
• Nguyen Ngoc Trai,
• Nguyen Phuong Thuy,
• Hoang Dang Khoa Do,
• Nhu Hoa Thi Tran and
• Kieu The Loan Trinh

Beilstein J. Nanotechnol. 2024, 15, 396–415, doi:10.3762/bjnano.15.36

• peroxide or organic hydroperoxide (ROOH) to produce ROS. In nature, biological systems commonly use catalase (CAT) and glutathione peroxidase (GPx) as preventive antioxidants to degrade hydrogen peroxide, which is a precursor of ROS. CAT, containing a heme active site, and GPx, containing a selenium active

• radicals through several pathways such as chelating transition metals, quenching singlet oxygens, decomposing hydrogen peroxides, and deactivating superoxides without generating active radicals [17][18][19]. Transition metals such as Fe2+ and Cu2+ initiate a Fenton reaction in the presence of hydrogen

Exploring the relationships between physiochemical properties of nanoparticles and cell damage to combat cancer growth using simple periodic table-based descriptors

• Joyita Roy and
• Kunal Roy

Beilstein J. Nanotechnol. 2024, 15, 297–309, doi:10.3762/bjnano.15.27

• are involved in the Fenton reaction, which generates hydroxyl radicals from hydrogen peroxide. Similarly, the Haber–Weiss reaction involves the oxidized forms of redox-active metal ions and superoxide anions, which generate the reduced form of the metal ion. This reduced form can then be coupled to

Nanoarchitectonics of photothermal materials to enhance the sensitivity of lateral flow assays

• Elangovan Sarathkumar,
• Rajasekharan S. Anjana and
• Ramapurath S. Jayasree

Beilstein J. Nanotechnol. 2023, 14, 988–1003, doi:10.3762/bjnano.14.82

• , bleaching, and degradation. Gold nanoparticles possess intrinsic peroxidase-like activity, which converts particular peroxidase substrates into coloured products in the presence of hydrogen peroxide. The enzyme-like properties of nanomaterials have been utilized in various LFA formats. The inclusion of

Silver-based SERS substrates fabricated using a 3D printed microfluidic device

• Phommachith Sonexai,
• Minh Van Nguyen,
• Bui The Huy and
• Yong-Ill Lee

Beilstein J. Nanotechnol. 2023, 14, 793–803, doi:10.3762/bjnano.14.65

• from Krackeler Scientific (USA). Methyl alcohol, hydrogen peroxide (35%), sodium hydroxide (<97%), ammonia water (25–29%), acetone (99.5%), ethyl alcohol (95%), and 2-propanol (99.5%) were bought from Daejung (Republic of Korea). The Formlabs 3D printer and clear V4 resin were purchased from Formlabs

Bismuth-based nanostructured photocatalysts for the remediation of antibiotics and organic dyes

• Akeem Adeyemi Oladipo and
• Faisal Suleiman Mustafa

Beilstein J. Nanotechnol. 2023, 14, 291–321, doi:10.3762/bjnano.14.26

• reaction, along with other species such as oxygen, hydrogen peroxide, and persulfate. This excited electron reduces an acceptor, and the acceptor's hole oxidises donor molecules. What happens to the excited electron and hole depends on the relative positions of conduction band and valence band of the

A novel approach to pulsed laser deposition of platinum catalyst on carbon particles for use in polymer electrolyte membrane fuel cells

• Bogusław Budner,
• Wojciech Tokarz,
• Sławomir Dyjak,
• Andrzej Czerwiński,
• Bartosz Bartosewicz and
• Bartłomiej Jankiewicz

Beilstein J. Nanotechnol. 2023, 14, 190–204, doi:10.3762/bjnano.14.19

• properties of the investigated catalysts. The number of electrons obtained in the oxygen reduction reaction (the number of electrons per O2 molecule) on electrodes made of the tested catalytic materials, and the resulting amount of hydrogen peroxide produced were determined based on polarization curves

• recorded using a rotating electrode with an RRDE ring [42]. The number of electron was calculated as: while the amount of hydrogen peroxide was calculated from the equation: where ID is the disc current, IR is the ring current, and η is the electrode collection coefficient. The results of RRDE measurements

• electrode. The oxygen reduction efficiency of both commercial catalysts is similar (Figure 5a, Table 2), but the catalyst HiSpec 3000 has a small advantage due to the lower percentage of hydrogen peroxide in the oxygen reduction products (Figure 5d). The fabricated catalysts of series A, B, C, and D also

Electrocatalytic oxygen reduction activity of AgCoCu oxides on reduced graphene oxide in alkaline media

• Iyyappan Madakannu,
• Indrajit Patil,
• Bhalchandra Kakade and
• Kasibhatta Kumara Ramanatha Datta

Beilstein J. Nanotechnol. 2022, 13, 1020–1029, doi:10.3762/bjnano.13.89

• (K–L) method using Equation S1, Supporting Information File 1. The K–L plot (I−1 vs ω−1/2) obtained from the LSV curves in Figure 3b shows the linearity at different potentials (Figure 3c). Moreover, RRDE studies were carried out to measure the hydrogen peroxide generated during the electroreduction

Solar-light-driven LaFe_xNi_1−xO₃ perovskite oxides for photocatalytic Fenton-like reaction to degrade organic pollutants

• Chao-Wei Huang,
• Shu-Yu Hsu,
• Jun-Han Lin,
• Yun Jhou,
• Wei-Yu Chen,
• Kun-Yi Andrew Lin,
• Yu-Tang Lin and
• Van-Huy Nguyen

Beilstein J. Nanotechnol. 2022, 13, 882–895, doi:10.3762/bjnano.13.79

• substances in wastewater [16]. Among these procedures, the Fenton method causes numerous interests due to its convenience and effectiveness. Notably, the Fenton method can produce many hydroxyl radicals (∙OH) by introducing divalent iron solution and hydrogen peroxide, as shown in Equation 1 below. The

• hydrogen peroxide can be remarkably transformed into redox radicals, followed by destroying the organic pollutants. Meanwhile, the remaining divalent iron complexes in the system can return to the circulation of hydrogen peroxide reaction and continuously form new hydroxide radicals [20]. Therefore, based

• within 105 min. Based on the 1st order kinetic analysis, the reaction rate constants (k) at pH 1.5, 3.5, and 5.5 were 0.0254, 0.0506, and 0.002, respectively. While the pH value was too high, the hydrogen peroxide in the solution was easily decomposed into oxygen and water [55]. On the other hand, when

Stimuli-responsive polypeptide nanogels for trypsin inhibition

• Petr Šálek,
• Jana Dvořáková,
• Sviatoslav Hladysh,
• Diana Oleshchuk,
• Ewa Pavlova,
• Jan Kučka and
• Vladimír Proks

Beilstein J. Nanotechnol. 2022, 13, 538–548, doi:10.3762/bjnano.13.45

• obtained from Lach-Ner (Czech Republic). The solvents were purified and dried by a standard procedure before use. Aminopropan-2-ol (purified by vacuum distillation) was purchased from Alfa Aesar (Kandel, Germany). 1,6-Diaminohexane, HBr 33 wt % in acetic acid, 30% hydrogen peroxide solution (w/w) in water

A non-enzymatic electrochemical hydrogen peroxide sensor based on copper oxide nanostructures

• Irena Mihailova,
• Vjaceslavs Gerbreders,
• Marina Krasovska,
• Eriks Sledevskis,
• Valdis Mizers,
• Andrejs Bulanovs and
• Andrejs Ogurcovs

Beilstein J. Nanotechnol. 2022, 13, 424–436, doi:10.3762/bjnano.13.35

• , Latvia Institute of Solid State Physics, University of Latvia, Kengaraga street 8, Riga, LV-1063, Latvia 10.3762/bjnano.13.35 Abstract This article describes the synthesis of nanostructured copper oxide on copper wires and its application for the detection of hydrogen peroxide. Copper oxide petal

• qualitative detection of H2O2 in real samples, as well as for the quantitative determination of its concentration. Keywords: copper oxide; electrochemical sensor; hydrogen peroxide; nanostructures; Introduction Hydrogen peroxide, a strong oxidant and an essential intermediate product in many biomedical

• milk and mouthwash samples. Materials and Methods Materials Ammonium persulfate ((NH4)2S2O8, CAS number: 7727-54-0), sodium hydroxide (NaOH, CAS number: 1310-73-2), and hydrogen peroxide solution (H2O2, 30%, CAS number: 7722-84-1) were purchased from Merck. Ascorbic acid (C6H8O6, CAS number: 50-81-7

Thermal oxidation process on Si(113)-(3 × 2) investigated using high-temperature scanning tunneling microscopy

• Hiroya Tanaka,
• Shinya Ohno,
• Kazushi Miki and
• Masatoshi Tanaka

Beilstein J. Nanotechnol. 2022, 13, 172–181, doi:10.3762/bjnano.13.12

• remove the oily materials, and rinsed with a mixture of sulfuric acid and hydrogen peroxide to remove the organic materials. It was then etched with a mixture of hydrochloride and hydrogen peroxide to form an ultrathin oxide layer before it was introduced to an ultrahigh-vacuum (UHV) chamber. The sample

Morphology-driven gas sensing by fabricated fractals: A review

• Vishal Kamathe and
• Rupali Nagar

Beilstein J. Nanotechnol. 2021, 12, 1187–1208, doi:10.3762/bjnano.12.88

• 2–3 µm length) by a hydrothermal method and calcined the fabricated nanostructure precursors in air [84]. Figure 23a–f shows SEM and TEM micrographs with selected-area electron diffraction (SAED) patterns of the Co3O4 nanostructures. Hydrogen peroxide (H2O2) was detected by an electrochemical sensor

Modification of a SERS-active Ag surface to promote adsorption of charged analytes: effect of Cu²⁺ ions

• Bahdan V. Ranishenka,
• Andrei Yu. Panarin,
• Irina A. Chelnokova,
• Sergei N. Terekhov,
• Peter Mojzes and
• Vadim V. Shmanai

Beilstein J. Nanotechnol. 2021, 12, 902–912, doi:10.3762/bjnano.12.67

• ]. The same modification protocol was applied as for glass and the silicon supports. The substrates were treated with a 1:1 (by mass) mixture of concentrated H2SO4 and 30% hydrogen peroxide water solution for 2 h, rinsed with distilled water, and dried. The cleaned substrates were treated with a solution

Comprehensive review on ultrasound-responsive theranostic nanomaterials: mechanisms, structures and medical applications

• Sepand Tehrani Fateh,
• Lida Moradi,
• Elmira Kohan,
• Michael R. Hamblin and
• Amin Shiralizadeh Dezfuli

Beilstein J. Nanotechnol. 2021, 12, 808–862, doi:10.3762/bjnano.12.64

• concentration supports this conclusion [202]. Dong and colleagues prepared plasma MBs by mixing plasma gas and surfactant using an emulsification process. These MBs released the loaded drug and also generated active free radicals (including nitric oxide and hydrogen peroxide) in response to US irradiation [205

Recent progress in magnetic applications for micro- and nanorobots

• Ke Xu,
• Shuang Xu and
• Fanan Wei

Beilstein J. Nanotechnol. 2021, 12, 744–755, doi:10.3762/bjnano.12.58

• enabled actuation, control, and observation of the FMSM. In most mobile sensing applications, microrobots are driven by chemical fuels such as hydrogen peroxide (H2O2) and surfactants. In contrast, magnetic drives have good biocompatibility and external power supply. For example, a porous microelectrode

Impact of GaAs(100) surface preparation on EQE of AZO/Al₂O₃/p-GaAs photovoltaic structures

• Piotr Caban,
• Rafał Pietruszka,
• Jarosław Kaszewski,
• Monika Ożga,
• Bartłomiej S. Witkowski,
• Krzysztof Kopalko,
• Piotr Kuźmiuk,
• Katarzyna Gwóźdź,
• Ewa Płaczek-Popko,
• Krystyna Lawniczak-Jablonska and
• Marek Godlewski

Beilstein J. Nanotechnol. 2021, 12, 578–592, doi:10.3762/bjnano.12.48

• aqueous solutions are used with the addition of an oxidizer – usually hydrogen peroxide (H2O2). Such an etchant is able to turn GaAs into oxide and dissolve the created oxides “at the same time”. The popular etchants are H2SO4/H2O2/H2O, NH4OH/H2O2/H2O, and citric acid (CA)-based etchants – CA/H2O2/H2O [17

• minutes raised it to room temperature (RT). Just before the etching process, the dissolved CA in DIW was mixed (1:1, v:v) with hydrogen peroxide (30%). The solution temperature was set to 24 °C and kept at this value during the etching process for 2 min in a USC. The etching rate of such a solution, with

A review on nanostructured silver as a basic ingredient in medicine: physicochemical parameters and characterization

• Gabriel M. Misirli,
• Kishore Sridharan and
• Shirley M. P. Abrantes

Beilstein J. Nanotechnol. 2021, 12, 440–461, doi:10.3762/bjnano.12.36

• from the damaged respiratory chain since they depend on thiol groups which are occupied by silver ions. The increase in superoxide and hydrogen peroxide anions in the reaction with iron (Fenton reaction), according to Equation 2 [104] and as described in Figure 6, are indicative of the deleterious

Nanocasting synthesis of BiFeO₃ nanoparticles with enhanced visible-light photocatalytic activity

• Thomas Cadenbach,
• Maria J. Benitez,
• A. Lucia Morales,
• Cesar Costa Vera,
• Luis Lascano,
• Francisco Quiroz,
• Alexis Debut and
• Karla Vizuete

Beilstein J. Nanotechnol. 2020, 11, 1822–1833, doi:10.3762/bjnano.11.164

• radicals (•O2−) and hydrogen peroxide (H2O2), while the photogenerated electron hole h+ reacts with H2O to form hydroxyl radicals (•OH). The latter species can additionally be formed by disproportionation of •O2− radicals and a subsequent chain reaction. It has been reported previously that hydroxyl

Antimicrobial metal-based nanoparticles: a review on their synthesis, types and antimicrobial action

• Matías Guerrero Correa,
• Fernanda B. Martínez,
• Cristian Patiño Vidal,
• Camilo Streitt,
• Juan Escrig and
• Carol Lopez de Dicastillo

Beilstein J. Nanotechnol. 2020, 11, 1450–1469, doi:10.3762/bjnano.11.129

• microorganisms [151]. Superoxide radicals (O2−), hydroxyl radicals (•OH), hydrogen peroxide (H2O2), and singlet oxygen (1O2) are the most well-known ROS. The mechanism that better explains the synthesis of ROS from NPs is based on their photocatalytic activity (Figure 5). Metal compounds receive enough energy

• , genes related to the general stress response were upregulated. Genes protecting against hydrogen peroxide oxidative damage, catalase/hydroperoxidase, superoxide radicals degradation genes, superoxide dismutase, and superoxide removal transcriptional activator, were upregulated in a range varying from